If you have been following my <a target="_blank" rel="noopener noreferrer" href="https://concentratingonchromatography.com/">Concentrating on Chromatography podcast</a>, you know that I am constantly searching for the cutting edge of separation science. After years of interviewing the brightest minds in the field, it has become clear to me that the <a target="_blank" rel="noopener noreferrer" href="https://www.multidimensionalchromatography.com/">Multidimensional Chromatography Workshop (MDCW)</a> is undeniably the best up-and-coming event in our industry.While I was unfortunately traveling in Asia during the most recent session, I was able to catch every detail thanks to the incredible work of <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLg-M6fM-05MrGrDggkl_UKzzcHPWPmssh">LabRulez</a>. A huge thank you to Ivo Novotný and the LabRulez team for providing Open Access video presentations of the event. Their <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">portal </a>is an invaluable resource for anyone who needs to find technical information quickly and efficiently.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_2_65b378bf01.jpg" alt="Organomation: MDCW: The Premier Up-and-Coming Event in Chromatography" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_2_65b378bf01.jpg 245w," sizes="100vw" width="1044" height="455"><h3>The Minds Behind the Magic</h3>I have had the privilege of featuring the core organizers of MDCW on my podcast, including Katelynn Perrault Uptmor, Dwight Stoll, and Petr Vozka. Their dedication to creating a space where forensic chemistry, environmental analysis, and metabolomics intersect is what makes this workshop so unique. The event is a perfect showcase for how multidimensional techniques—like GC×GC and 2D-LC—are essential for tackling the world's most complex samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_265c9ec21e.jpg" alt="Organomation: MDCW: The Premier Up-and-Coming Event in Chromatography" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_265c9ec21e.jpg 245w," sizes="100vw" width="792" height="230"><h3>Where Sample Prep Meets High-Resolution Analysis</h3>As we often discuss at Organomation, even the most advanced chromatographic systems depend on meticulous sample preparation. Two presentations highlighted in the LabRulez playlist perfectly illustrate the critical role of <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-solvent-evaporation">solvent evaporation</a> and <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-sample-concentration">sample concentration</a>.<h3>Chemical Fingerprints: Emma Macturk’s Quest for Hidden Data</h3><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=1W5197sp6IY">Emma Macturk</a>, working in Dr. Katelynn Perrault Uptmor’s lab, is redefining how we look at one of the oldest forms of forensic evidence: the fingerprint. While traditional forensics relies on the physical patterns of ridges and whorls, these are often incomplete or smudged in real-world scenarios. Emma’s research shifts the focus to the chemical residue left behind, which can provide vital "class characteristics" like the biological sex and relative age of a suspect.Her optimized workflow is a masterclass in handling complex biological matrices. Using a cotton swab to extract residue from surfaces, the samples are centrifuged and then "<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">blown down</a>" (a critical concentration step for any trace analysis) before <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-reconstitution">being reconstituted for GC×GC-TOFMS</a>.What makes her work truly fascinating—and highly relevant for our readers at Organomation—is the discovery of anthropogenic compounds. Emma identified UVB blockers like octocrylene and various moisturizers hidden within the natural sterols and fatty acids of the skin. The power of multidimensional chromatography allows forensic scientists to resolve these external "lifestyle" markers from endogenous skin compounds, potentially providing a much more detailed profile of a suspect than a physical print ever could.<h3>The "Green" Revolution: Grace Saunders and the Future of Ballistics</h3><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=ClD4fjZMNtA">Grace Saunders</a> addressed a looming crisis in forensic ballistics: the shift toward "green ammunition." For decades, the gold standard for detecting gunshot residue (GSR) has been SEM-EDS, which looks for heavy metals like lead, barium, and antimony. However, modern environmental and health standards are leading manufacturers to omit these metals. This means that traditional standards are failing to identify GSR in cases involving green rounds.Grace’s research proposes a dual-pronged approach, using GC×GC to target Organic Gunshot Residue (OGSR). Her liquid extraction protocol is meticulous: samples are extracted in methanol, "<a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-evaporation-to-dryness">evaporated to dryness under nitrogen</a>," and then reconstituted. This ensures that volatile and semi-volatile nitroaromatic compounds, such as nitroglycerin and diphenylamine, are concentrated enough for detection.By optimizing parameters like the modulation period (2.5 seconds) and switching to hydrogen carrier gas, Grace was able to resolve these critical markers from the complex background "noise" of human skin. Her work isn't just about better chemistry; it’s about legal survival. As she noted, forensic methods must meet Federal Rule 702 for admissibility in court. Without the organic profiling Grace is developing, evidence from a "green" firearm discharge might never make it past a judge.<h3>The Future of Chromatography</h3>The workshop also featured brilliant presenters like <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=YJm_JwHbArE">Ryland Giebelhaus</a>, whose work on the metabolomics of cannabis exposure during pregnancy shows the real-world impact of these technologies.The MDCW isn't just another conference; it is a community-driven powerhouse that bridges the gap between proof-of-concept and field-ready applications. Whether you are looking for advanced data reduction strategies or the latest in high-resolution mass spectrometry, this is the event to watch.<blockquote>If you missed it this year like I did, I highly recommend visiting the <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLg-M6fM-05MrGrDggkl_UKzzcHPWPmssh">LabRulez portal</a> to see the full breadth of research presented!</blockquote>

MDCW: The Premier Up-and-Coming Event in Chromatography

Visit the LabRulez booth at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/871">analytica 2026</a> in Munich, 24. - 27. March 2026! You can find us in Hall A1, Booth A1.506. At the booth, you will be able to explore live demonstrations of how the LabRulez portals work and see selected analytical instruments from our pre-owned marketplace section.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg" alt="LabRulez at Analytica 2026: Hall A1 Floor Plan and Booth Location" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg 245w," sizes="100vw" width="1516" height="881"><h3>Would you like to learn how the LabRulez portals work?</h3>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">LabRulezLCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/">LabRulezGCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/">LabRulezICPMS</a><ul><li>A unique online solution for your marketing</li><li>A targeted audience from the analytical chemistry community</li><li>Modern technologies and a unique concept</li><li>Design optimized for most smart devices – PC, mobile, and tablet</li><li>Advanced statistical tools fully available to users</li></ul><h3>Services Offered</h3><h4>News + Company Updates</h4><ul><li>Publish news related to your instrumentation, applications, services, events, job openings, and more</li><li>News is shared both on our portals and across our social media channels</li></ul><h4>Library – All Documents in One Place</h4><ul><li>Applications, posters, presentations, technical articles, brochures, specifications</li><li>Fast and advanced search capabilities</li><li>Over 32,000 documents currently available in our database</li></ul><h4>Webinars</h4><ul><li>Upcoming and on-demand webinars from the field of analytical chemistry</li><li>More than 5,500 webinars covering chromatography, mass spectrometry, and spectroscopy</li></ul><h4>Careers</h4><ul><li>Targeted job listings in analytical chemistry</li><li>Clear filtering by specialization or location</li><li>Increased visibility for job postings</li></ul><h4>Companies</h4><ul><li>Company profile with key information and contacts</li><li>Integration of all your activities on our portal: News, Library documents, Webinars, Upcoming Events, Careers, and mentions by partners or customers</li><li>Connection to your Products listed on LabRulez portals</li></ul><h4>Products and Services</h4><ul><li>Comprehensive overview of instrumental techniques and services</li><li>Targeting the analytical chemistry community and customers in the growing online environment</li></ul><h4>Marketplace</h4><ul><li>Buying and selling pre-owned analytical equipment</li><li>We purchase analytical instrumentation of all brands and ages</li><li>Sell your equipment through LabRulez</li><li>Request and purchase complete systems, modules, or spare parts with warranty and service</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg" alt="LabRulez at analytica 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg 88w," sizes="100vw" width="1600" height="2844"><h3>What Will Be on Display at Our Booth?</h3>Come and explore selected spare parts and modules from our marketplace section. These include both new, tested, and pre-owned items.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar">LabRulezLCMS Marketplace</a></h4>Spare parts for LC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=378">Vacuum turbo pumps for LC/MS</a></li></ul>Spare parts for HPLC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=397">Degassers for HPLC/UHPLC</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=368&amp;search=valve">Automatic valves for HPLC</a></li><li>HPLC components for Agilent 1100, 1200, and 1260 Infinity II series</li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=377">HPLC lamps</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=48">HPLC columns</a></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar">LabRulezGCMS Marketplace</a></h4>Spare parts for GC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=367&amp;search=turbo">Turbo pumps for GC/MS</a></li></ul>Spare parts for GC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366&amp;search=EPC">EPC modules</a></li></ul>Sample injection<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/432">Autosampler 7693A for GC</a></li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=7">GC columns </a>and selected accessories</li></ul>

LabRulez at analytica 2026

Anna Vanluchene&nbsp;from UCT Prague’s&nbsp;Department of Chemical Engineering has received a&nbsp;prestigious start-up grant from the Dagmar Procházková Fund. However, she did not receive funding right away. In this interview, she describes how she developed ten versions of her&nbsp;Illuminating Flow&nbsp;project idea (combining photocatalysis with flow reactors for pharmaceutical synthesis). She explains why she considers perseverance to be crucial when applying for grants, how international experience has influenced her approach to team management, and how her research can reduce the chemical industry’s&nbsp;dependence on fossil fuels and imports from China.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg 127w," sizes="100vw" width="1128" height="1387"><h5>What did the Dagmar Procházková Fund grant mean to you?</h5>I&nbsp;consider it to be a&nbsp;great success. It is the first injection of funding that will allow me to ensure full independence for my research endeavour, to start my own research group, and to fund students so I&nbsp;can get started properly.<h5>What have been your previous experiences with grants?</h5>During my doctorate, a cotutelle (international doctorate under dual supervision), I&nbsp;was funded by a&nbsp;grant from the French government. Then I&nbsp;worked at the Academy of Sciences of the Czech Republic (CAS) and received a&nbsp;Marie Skłodowska-Curie Action (MSCA) Postdoctoral Fellowship to go abroad. The idea for my now-funded project was developed about two years ago and, since then, I&nbsp;have gradually developed and adapted the idea for various grant calls. I&nbsp;submitted about ten different versions of the proposal. I&nbsp;did not receive a&nbsp;grant from the Dagmar Procházková Fund last year, but this year, my application was successful.<h5>This probably requires a&nbsp;great deal of patience and perseverance.</h5>Certainly, because the success rates for most grants have been declining for some time. But as a&nbsp;motivational example, I&nbsp;will tell the story of Timothy Noel, a&nbsp;Belgian professor of chemistry living in the Netherlands. He applied for the prestigious European Research Council (ERC) grant, which is among the most sought-after in Europe, seven times. But no failure deterred him and eventually he succeeded and opened the door to potentially massive grant funding. He was already one of the world’s&nbsp;top scientists in the field at that time and openly described his journey on his blog <a target="_blank" rel="noopener noreferrer" href="https://www.noelresearchgroup.com/2022/03/17/my-personal-story-to-obtain-an-erc-grant-7-submissions-4-interviews-and-6-heartbreaks/">blog</a>.<h5>What advice does this convey to other grant applicants and early career researchers?</h5>Start early, read a&nbsp;lot, don’t&nbsp;give up, and—most importantly—apply repeatedly. Learn from rejections and overcome possible frustration from failures. Read blogs and books by successful people, where you will find not only the glorious results of their work, but also the hardships they faced over their entire journeys. Of course, building your team and laboratory is impossible without finances. I&nbsp;myself still hope that I&nbsp;will be able to receive even bigger grants in the future.<h5>How has your international experience influenced your scientific approach?</h5>A&nbsp;lot and on several levels. Different laboratories teach you how to do&nbsp;things differently. You gain varied experience about how different institutions function. You see other people’s&nbsp;positive motivations, their ability to be ambitious without negativity, their involvement in institutional matters, their openness to cooperation with companies (e.g., tech transfers, spin-offs). The most important thing is to broaden your horizons. I&nbsp;see going abroad as a&nbsp;necessity. What I&nbsp;have taken away the most is drive, great support, and the idea that scientific output is not just about metrics, but also about dedication to one’s&nbsp;topic.<h5>What is your Illuminating Flow: Transport Phenomena in Photocatalysis about, in layperson’s&nbsp;terms, and how is it unique?</h5>Most of today’s&nbsp;chemical industry is still based on thermal processes and fossil fuels. Photochemistry enables electrification, where the energy source is photons delivered by LEDs, which can generate electricity from renewable sources. Current research focuses mainly on chemical reactions and their mechanisms, but as a&nbsp;chemical engineer, I&nbsp;focus on designing processes and reactors suitable for industrial use. In batch reactors, light fades rapidly with distance from a&nbsp;source, so much of a&nbsp;reaction mixture is not illuminated. Flow reactors solve this problem, but they bring new challenges such as working with solid catalysts and subsequently scaling up production and achieving higher production rates of the desired chemicals at a&nbsp;given scale.One can imagine a&nbsp;transparent tube with a&nbsp;catalyst on the walls, upon which light shines and through which reactants flow. This project has a&nbsp;unique emphasis on engineering solutions and overall process efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg 241w," sizes="100vw" width="1228" height="799"><h5>So, were you inspired by a&nbsp;gap in the market to connect photocatalysis with transport phenomena?</h5>Exactly. I&nbsp;combine my areas of expertise: microfluidics, photocatalytic degradation of organic substances (CAS), and synthesis (MSCA Postdoctoral Fellowship). The idea itself is not new, and pharmaceutical companies are very interested in “greener” photochemistry, but in practice, there is often a&nbsp;lack of appropriate engineering solutions and apparatus for industrial use.<h5>What are the practical applications of your work and what substances are you focusing on?</h5>Mainly on pharmaceuticals and on the synthesis of so-called fine chemicals, which are often the building blocks for the production of pharmaceuticals. There is also a&nbsp;geopolitical dimension to this, i.e. less dependence on imports from China and sustainable synthesis in Europe where it makes economic sense.<h5>And what chemicals are you specifically talking about?</h5>For example, building blocks for advanced synthesis, compounds prepared by trifluoromethylation reactions, or products of oxidation reactions with singlet oxygen. At the same time, we focus on reactions that are, in the classical design process, less safe or technologically demanding, where new approaches, such as photochemistry in flow reactors, could be safer and have better process control. Of course, this is not a&nbsp;universal solution for all types of reactions.<h5>The goal of this project?</h5>I&nbsp;plan to start a&nbsp;fully functional laboratory and research team, create high-quality experimental data on selected molecules and based on them, try to build cooperation with industrial partners. Without data, it is impossible to come to companies with just an idea. Within three years, I&nbsp;would like to have results that can be realistically presented and further developed.<h5>What are the main challenges in transport phenomena during photocatalysis?</h5>The methodology for repeatability of experiments in photochemistry is relatively demanding and there are unforeseen obstacles in building apparatus. Also, the scale-up from microliters to a&nbsp;larger scale.<h5>What methodology will you use, and how big are the microreactors and their flow rates?</h5>I&nbsp;have two different directions in methodological design. The first direction involves microreactors the size of a&nbsp;laboratory slide. You make a&nbsp;structure using a&nbsp;laser, and then you have to cast it and make a&nbsp;microreactor. This allows you to quickly adjust the geometry of the reactor. This method is, of course, not applicable in the commercial setting, but it is ideal for studying transport phenomena and precise measurements.The second direction involves reactors that are flow cells. These are already larger, approximately 15 x 15 centimetres, and their flow rates are in the order of millilitres per hour. This is the initial scale that we will further increase during the project.<h5>There is a&nbsp;big difference between a&nbsp;flow rate of microlitres per hour and industrial needs. Will it not work differently in reality?</h5>Our research will focus on studying the phenomena themselves for now, and scaling will be addressed later. In addition, we will combine the experimental data obtained with computer simulations that will help design suitable conditions for a&nbsp;larger scale. For some high-value fine chemicals, these scales, combined with continuous operation or parallelization of reactors, may already be practically usable.<h5>What catalysts will you use and how will you attach them to the reactor walls?</h5>I&nbsp;am focusing on heterogeneous photocatalysis, and we will mainly use graphitic carbon nitride and its more advanced modifications. These are semiconductor materials that can be synthesized relatively easily and are suitable for immobilization on glass reactor walls. A&nbsp;key part of this project is the creation of a&nbsp;stable catalytic layer for long-term flow-through operations. To increase the contact of reactants with the catalyst, we will also consider multiphase modes, for example, gas bubbling, in order to disrupt the otherwise laminar flow.<h5>Why did you choose this field and the Department of Chemical Engineering?</h5>During my postdoc in Belgium, the department had an opening for an Assistant Professor position that caught my attention and I&nbsp;applied for it. I&nbsp;did my undergraduate, graduate, and initial doctoral studies here, and I&nbsp;love the department. I&nbsp;have a&nbsp;Bachelor’s&nbsp;degree in Chemistry.<h5>Are you collaborating with anyone?</h5>We collaborate with BUT Brno focusing on creating layers and immobilizing catalysts on glass, as well as with the Institute of Chemical Process Fundamentals of the Academy of Sciences of the Czech Republic. And as for organic synthesis, we are connected with Ghent University via postdoc internships. At the same time, my colleague Viola Tokárová and I&nbsp;received a&nbsp;Czech Science Foundation grant in cooperation with BUT Brno and Masaryk University, with our part of the project focusing on the use of flow reactors for photochemical reactions and testing the antibacterial properties of photocatalytic materials. And I&nbsp;am writing other grant proposals in which I&nbsp;am trying to build new collaborations.<h5>What does the creation of an independent research group at UCT Prague look like?</h5>I&nbsp;started by renovating the premises that were assigned to me and gradually building my team. It is important for research work to have Ph.D. students; I&nbsp;have already hired one and we will recruit more. In addition to building the group, I&nbsp;will engage in securing further funding for the group, so I&nbsp;will be writing more grant proposals. It is important to think far enough in advance when it comes to prospective funding for a&nbsp;research group.<h5>What type of students are you looking for?</h5>The laboratory and team I&nbsp;are building will be very multidisciplinary, just like the area I&nbsp;am working on. That is why I&nbsp;am looking for students who are attracted to true multidisciplinary research, those who, for example, have knowledge of engineering, but who don’t&nbsp;mind a&nbsp;little bit of pure chemistry. One student in their own right does not have to (and cannot) know every subject, so I&nbsp;will ideally have a&nbsp;team consisting of different people with different research backgrounds. Motivated, DIY-type students who would rather enthusiastically build or invent something themselves than conduct repetitive measurements. Organic or analytical chemists will also find their place here. If this topic is interesting to students in any way, they can definitely contact me. I&nbsp;am also open to interdepartmental cooperation with other UCT Prague Faculties.<h5>How would you describe your path to photocatalysis/chemical engineering?</h5>Studying Chemistry as an undergrad gave me a&nbsp;broad perspective, but I&nbsp;was gradually narrowing my focus and eventually chose engineering. Chemical engineering intrigued me with its logic and was the easiest for me to grasp at the time. But I&nbsp;have always enjoyed working on projects more than the studies themselves. Even during my Bachelor studies, I&nbsp;really enjoyed and was interested in the Professor Štěpánek Group’s&nbsp;projects, where I&nbsp;was doing something completely different than I&nbsp;do&nbsp;now. I&nbsp;only got into photochemistry during my time at CAS and then, during my postdoctoral fellowship, I&nbsp;devoted myself to electrochemistry. My current focus is, thus, a&nbsp;natural interlinking of all these areas. Consequentially, I&nbsp;developed an awareness of the necessity to become independent and return to the department with my own, different research agenda, which, in my opinion, is an important and correct basis for establishing my own research group.<h5>What is the biggest challenge of this project for you?</h5>The transition from being a&nbsp;postdoc to a&nbsp;leadership position is a&nbsp;big change for me and I&nbsp;think it is not talked about enough. It means a&nbsp;shift from my own experimental work to leading a&nbsp;team, planning and delegating tasks, and motivating students. From a&nbsp;practical point of view, one of the main challenges is the transfer of reactions from the microscale to functional systems, the construction of reactors, the immobilization of catalysts, and generally confirming that this direction makes sense in the long term and that it has future potential.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg 155w," sizes="100vw" width="830" height="839">

I waited two years for a start-up grant and wrote ten versions of my project idea

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The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Hydrophilic Polar Selectivity and Performance!The Kinetex C8 HPLC column is a core-shell-based particle with a bonded silica phase ideal for the analysis of very hydrophobic compounds. This versatile column can easily upgrade existing fully porous 5 µm and 3 µm methods to shorten run-time, increase sensitivity, and even provide greater resolution with much higher efﬁciency levels.<ul><li>Compatible with All Analytical HPLC/UHPLC Systems*</li><li>Balancing Performance &amp; Retention</li><li>USP:L7</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Kinetex_Core_Shell_C8_HPLC_Column_eb663e39df.webp" alt="Phenomenex: Kinetex Core-Shell C8 HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Kinetex_Core_Shell_C8_HPLC_Column_eb663e39df.webp 245w," sizes="100vw" width="500" height="150"><ul><li>Carbon Load: 8 (effective), 8 (effective) %</li><li>Surface Area (m²/g): 200</li><li>Particle Size (μm): 1.7, 2.6, 5</li><li>Recommended Use: Minimized hydrophobic retention for highly hydrophobic compounds</li></ul><h4>Balancing Speed and Retention</h4>The Kinetex core-shell C8 provides the same Kinetex performance but with a little less hydrophobic retention in comparison to the Kinetex C18 column. This C8 column is ideal for extremely hydrophobic compounds that might be too strongly retained on a traditional C18 phase column.<blockquote>Stationary phase Kinetex Core-Shell C8 is provided in these column types: analytical and preparative</blockquote><h3>Kinetex Core-Shell Technology Columns</h3>Kinetex Core-Shell Technology delivers dramatic improvements in efficiency over conventional fully porous media, which can be leveraged to increase resolution, significantly improve productivity, reduce solvent consumption, and decrease costs. Whether you are running high-performance liquid chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC) methods, the Kinetex core-shell family can deliver shockingly improved performance over the current column you are using. Phenomenex designs, manufactures, and sells its very own silica and organo-silica core-shell particles.Advantages of Kinetex HPLC Columns<ul><li>Performance gains on ANY liquid chromatography system</li><li>System-to-system and lab-to-lab method portability</li><li>Improve the productivity of older, established methods.</li></ul><h4>How Does Core-Shell Technology Work?</h4>Core-shell technology in chromatography is a revolutionary approach that enhances the efficiency of HPLC systems while minimizing costs. Core-shell particles are designed with a solid, non-porous silica core surrounded by a porous outer layer. This unique structure allows for faster analyte mass transfer between the mobile and stationary phases, as diffusion occurs only through the thin, porous shell rather than the entire particle. This minimizes band broadening, leading to higher separation efficiency and sharper peaks.The consistency in size and shape of core-shell particles further enhances separation efficiency by reducing variability in analyte movement. As a result, core-shell HPLC columns provide high efficiency and resolution at lower backpressures, making them an ideal choice for labs looking to improve their existing HPLC systems without the need for costly UHPLC equipment.Core-shell technology thus offers a cost-effective alternative to upgrading to UHPLC systems, enabling labs to maximize the efficiency of their current HPLC setups. The formation of these particles through advanced sol-gel processing techniques ensures uniformity and reliability, making them a valuable tool in modern chromatography. By using the Kinetex HPLC column, laboratories can achieve faster analysis times and higher productivity while maintaining excellent separation performance.<h3>Kinetex Core-Shell Performance on Any LC System</h3>The 5 versatile particle sizes allow you to select the best fit for your instrument.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_5_particle_sizes_bbed75c36f.jpg" alt="Phenomenex: Five versatile particle sizes of Kinetex Core-Shell Technology Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_5_particle_sizes_bbed75c36f.jpg 245w," sizes="100vw" width="1341" height="333"><h3>Particle Chemistry</h3>Using sol-gel processing techniques that incorporate nano-structuring technology, a durable, homogeneous porous shell is grown on a solid silica core to create a Kinetex Core-Shell particle. This particle morphology results in less band broadening for all four sources of UHPLC band broadening compared to fully porous particles and thus delivers extremely high efficiencies.<ul><li>Optimized for Ultra-High Performance</li><li>Superior Core-Shell Quality</li><li>Core-Shell Scalability and Portability</li></ul>Kinetex particles are characterized by an exceptionally consistent size distribution, with particles being nearly monodispersed, meaning they are uniform in size. This precise uniformity plays a crucial role in minimizing variability within the column, leading to enhanced separation efficiency and sharper peaks.The nearly monodispersed nature of these particles ensures that the flow of the mobile phase remains consistent, reducing the likelihood of irregularities that can impact results. As a result, Kinetex columns deliver highly reliable and reproducible performance, making them ideal for achieving consistent analytical outcomes acrLC Kinetex Core-Shell Technolooss various applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_Kinetex_Polar_C18_vs_Fully_Porous_phase_a2729b64e5.jpg" alt="Phenomenex: Kinetex Polar C18 vs Fully Porous phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_Kinetex_Polar_C18_vs_Fully_Porous_phase_a2729b64e5.jpg 245w," sizes="100vw" width="1376" height="581"><h3>Core-shell vs Fully Porous</h3><h4>High-Efficiency‚ High-Density Particle</h4>The combination of a consistent, solid, high-density core along with proprietary column packing technologies in the Kinetex HPLC column ensures optimum bed structure and high column performance. This carefully designed core structure promotes uniform packing of the particles, which is essential for minimizing band-broadening effects that can arise from Eddy Diffusion.The manufacturing process of Kinetex columns is tightly controlled, focusing on factors such as particle size distribution, surface and bonding homogeneity, and packing quality. This meticulous engineering leads to uniform packing and minimized band-broadening, resulting in superior separation efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Core_shell_vs_Fully_Porous_60601b6fa3.jpg" alt="Phenomenex: Core-shell vs Fully Porous.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Core_shell_vs_Fully_Porous_60601b6fa3.jpg 245w," sizes="100vw" width="904" height="506"><h3>Expand Your Core-Shell Selectivity Toolbox</h3>Kinetex core-shell particle LC columns deliver exceptional performance enhancements across any LC system, offering unmatched efficiency and resolution. With a choice of 11 diverse stationary phases, these columns cater to a wide range of chromatographic applications, ensuring optimal separation for various analytes.Additionally, the availability of five versatile particle sizes allows for precise method tailoring, enabling both high-speed and high-resolution separations. Whether you're using HPLC or UHPLC systems, Kinetex columns provide the flexibility and performance needed to achieve superior analytical results.<h3>Top 5 Pros of Kinetex Core-Shell Technology</h3><ul><li>Productivity: Kinetex Core-Shell Technology significantly enhances method productivity with minimal effort. By simply replacing traditional, fully porous columns with Kinetex HPLC columns, users can achieve better resolution, sensitivity, and overall productivity without extensive method redevelopment. This easy switch allows for immediate improvements in chromatographic performance, making it a cost-effective upgrade to existing methods.</li><li>Portability The Kinetex Core-Shell columns are available in a range of particle sizes (1.3 µm to 5 µm), which ensures method portability across different HPLC and UHPLC systems. This scalability allows for consistent retention and selectivity across various particle sizes while accommodating different backpressure levels, making it easier to transfer methods between instruments.</li><li>Performance Kinetex Core-Shell Technology delivers superior chromatographic efficiency compared to fully porous particles. This efficiency boost enables chromatographers to maximize the performance of their HPLC/UHPLC systems, ensuring optimal results with higher resolution and sharper peaks, even under similar method conditions.</li><li>Phases With 11 unique phase selectivities available, Kinetex Core-Shell Technology offers unmatched versatility for method development. This wide selection of phase chemistries allows for tailored separations and simplified optimization, ensuring the best possible results for a wide range of applications.</li><li>Pressure Kinetex Core-Shell columns provide higher efficiency at lower system backpressures compared to fully porous columns. This allows users to achieve superior chromatographic performance on conventional LC instruments without the need for ultra-high-pressure systems, making it a practical choice for routine analyses.</li></ul>

Phenomenex Luna C8(2) HPLC Columns

The C8 column provides less hydrophobic retention than our C18 columns, but the density of the ligand bonding creates more steric based selectivity.

The C8 column provides less hydrophobic retention than our C18 columns, but the density of the ligand bonding creates more steric based selectivity.<ul><li>Extensive line of rugged particle sizes</li><li>Easy method scalability from HPLC to preparative and bulk purification LC</li><li>C8(2) Ultra-pure, metal-free silica (99.99% purity) (USP:L7)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Luna_C8_2_HPLC_Column_6479cab908.webp" alt="Phenomenex: Luna C8(2) HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Luna_C8_2_HPLC_Column_6479cab908.webp 245w," sizes="100vw" width="500" height="150"><ul><li>Carbon Load: 13.5, 13.5 %</li><li>Surface Area (m²/g): 400</li><li>Particle Size: 3, 5, 10, 15</li><li>Recommended Use: Separation of very hydrophobic compounds</li></ul><h4>Long Column Lifetimes and Excellent Performance</h4>Ultra-pure, metal-free silica (99.99 % purity) is the back bone of all Luna material. The resulting high quality particles have a surface smoothness, pore structure, and pore consistency to ensure a more uniform particle shape and greater reproducibility.<h4>Common Applications:</h4><ul><li>Doxepine, Doxylamine succinate, Fluoxetine, Glyburide, Ibuprofen Oral Suspension, Propranolol, Levonorgestrel, Ethinyl estradiol, Melengestrol acetate, Glucosamine</li></ul><blockquote>Stationary phase Luna C8(2) is provided in these column types: analytical, microbore, minibore, midbore, semi-preparative and preparative</blockquote><h5>Luna C8(2) HPLC Microbore, Minibore, MidBore, Analytical and Semi-preparative Columns are available with these parameters:</h5>Microbore Columns<ul><li>Column length (mm): 50, 150</li><li>Column ID (mm): 1</li><li>Particle size (µm): 3, 5</li></ul>Minibore Columns<ul><li>Column length (mm): 30, 50, 100, 150, 250</li><li>Column ID (mm): 2</li><li>Particle size (µm): 3, 5</li></ul>MidBore Columns<ul><li>Column length (mm): 30, 50, 150, 250</li><li>Column ID (mm): 3</li><li>Particle size (µm): 3, 5</li></ul>Analytical Columns<ul><li>Column length (mm): 30, 50, 75, 100, 150, 250</li><li>Column ID (mm): 4.6</li><li>Particle size (µm): 3, 5</li></ul>Semi-Prep Columns<ul><li>Column length (mm): 250</li><li>Column ID (mm): 10</li><li>Particle size (µm): 5</li></ul><h3>Phenomenex Luna HPLC Columns</h3>Luna HPLC columns are renowned for their outstanding reliability and adaptability in high-performance liquid chromatography (HPLC). Manufactured by Phenomenex, Luna HPLC columns are made from 99.999% ultra-pure, metal-free silica, with meticulous attention given to quality control across all aspects of its structure and chemistry. This guarantees that Luna columns consistently deliver reliable performance, ensuring dependable method reproducibility. The Luna series offers diverse selectivity, making it suitable for a broad range of chromatographic applications, from microbore and fast LC to preparative and bulk purification scales.All Luna products uphold the high standards our customers depend on. Featuring high surface area particles, Luna columns deliver improved resolution and performance, meeting the stringent requirements of HPLC users. Designed for longevity and consistent results, these columns are the trusted choice for both routine analyses and specialized separations, ensuring top-tier chromatographic outcomes.<h4>Explore Luna Columns</h4><ul><li>Proven Performance: Extensive line of rugged USP and Ph.Eur. phases</li><li>Maximum Reproducibility: Each column has both a certificate of analysis and a certificate of quality assurance</li><li>Ultra-High Purity: Metal free silica (99.99% purity) &nbsp;ensures a low activity surface and less secondary interactions</li><li>Scalable: Phases available in 3,5, 10 and 15 µm particle size for scaling from analytical to prep and bulk purification</li></ul>Explore resolution with 10 unique Luna selectivities and find your next selectivity tool. Combined with high surface area the Luna family of columns offers an excellent HPLC performance for a wide range of chromatographic applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phases_of_Luna_Columns_5b3ae06cee.jpg" alt="Phenomenex - Phases of Luna Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phases_of_Luna_Columns_5b3ae06cee.jpg 180w," sizes="100vw" width="565" height="490">

Phenomenex Intact XB-C8 LC columns

Biozen Intact XB-C8 column contains skillfully manufactured large pore core shell particles that provide narrower, taller peaks in conjunction with higher resolution.

Impurity profiling and characterization of intact biologic fragments is a challenging undertaking because of the need to identify very small differences between variants. Both bioZen Intact columns contain skillfully manufactured large pore core-shell particles that provide narrower, taller peaks in conjunction with higher resolution between the target HC/LC, Fc/Fab, or isoforms.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_Intact_XB_C8_HPLC_Column_c2159e0847.webp" alt="Phenomenex: Biozen Intact XB-C8 HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_Intact_XB_C8_HPLC_Column_c2159e0847.webp 245w," sizes="100vw" width="500" height="150"><ul><li>Separation Mode: Reversed Phase</li><li>Particle size: 3.6</li><li>Recommended Use: Fast separation of intact and subunit separation with hydrophobic selectivity</li></ul><h3>Phenomenex Biozen Biologics LC Columns</h3>With a new titanium BioTi™ biocompatible hardware to minimize priming, four particle platforms for optimal versatility and nine particle chemistries to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for protein analysis are seamlessly designed to bring peace of mind to your analysis of biologics through:<ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3>Biocompatible Flow Path with BioTi™ Hardware</h3>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"><h3>4 Advanced Particle Platforms</h3>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868">

Phenomenex Luna C8(2) HPLC Preparative Columns

The C8 column provides less hydrophobic retention than our C18 columns, but the density of the ligand bonding creates more steric based selectivity.<ul><li>Extensive line of rugged particle sizes</li><li>Easy method scalability from HPLC to preparative and bulk purification LC</li><li>C8(2) Ultra-pure, metal-free silica (99.99% purity) (USP:L7)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Luna_C8_2_HPLC_Column_6479cab908.webp" alt="Phenomenex: Luna C8(2) HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Luna_C8_2_HPLC_Column_6479cab908.webp 245w," sizes="100vw" width="500" height="150"><ul><li>Carbon Load: 13.5, 13.5 %</li><li>Surface Area (m²/g): 400</li><li>Particle Size: 3, 5, 10, 15</li><li>Recommended Use: Separation of very hydrophobic compounds</li></ul><h4>Long Column Lifetimes and Excellent Performance</h4>Ultra-pure, metal-free silica (99.99 % purity) is the back bone of all Luna material. The resulting high quality particles have a surface smoothness, pore structure, and pore consistency to ensure a more uniform particle shape and greater reproducibility.<h4>Common Applications:</h4><ul><li>Doxepine, Doxylamine succinate, Fluoxetine, Glyburide, Ibuprofen Oral Suspension, Propranolol, Levonorgestrel, Ethinyl estradiol, Melengestrol acetate, Glucosamine</li></ul><blockquote>Stationary phase Luna C8(2) is provided in these column types: analytical, microbore, minibore, midbore, semi-preparative and preparative</blockquote><h5>Luna C8(2) HPLC Axia™ Packed Preparative Columns are available with these parameters:</h5><ul><li>Column length (mm): 50, 100, 150, 250</li><li>Column ID (mm): 21.2; 30</li><li>Particle size (µm): 5, 10</li></ul><h3>Phenomenex Luna HPLC Columns</h3>Luna HPLC columns are renowned for their outstanding reliability and adaptability in high-performance liquid chromatography (HPLC). Manufactured by Phenomenex, Luna HPLC columns are made from 99.999% ultra-pure, metal-free silica, with meticulous attention given to quality control across all aspects of its structure and chemistry. This guarantees that Luna columns consistently deliver reliable performance, ensuring dependable method reproducibility. The Luna series offers diverse selectivity, making it suitable for a broad range of chromatographic applications, from microbore and fast LC to preparative and bulk purification scales.All Luna products uphold the high standards our customers depend on. Featuring high surface area particles, Luna columns deliver improved resolution and performance, meeting the stringent requirements of HPLC users. Designed for longevity and consistent results, these columns are the trusted choice for both routine analyses and specialized separations, ensuring top-tier chromatographic outcomes.<h4>Explore Luna Columns</h4><ul><li>Proven Performance: Extensive line of rugged USP and Ph.Eur. phases</li><li>Maximum Reproducibility: Each column has both a certificate of analysis and a certificate of quality assurance</li><li>Ultra-High Purity: Metal free silica (99.99% purity) &nbsp;ensures a low activity surface and less secondary interactions</li><li>Scalable: Phases available in 3,5, 10 and 15 µm particle size for scaling from analytical to prep and bulk purification</li></ul>Explore resolution with 10 unique Luna selectivities and find your next selectivity tool. Combined with high surface area the Luna family of columns offers an excellent HPLC performance for a wide range of chromatographic applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phases_of_Luna_Columns_5b3ae06cee.jpg" alt="Phenomenex - Phases of Luna Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phases_of_Luna_Columns_5b3ae06cee.jpg 180w," sizes="100vw" width="565" height="490">

Phenomenex Kinetex Core-Shell C8 Preparative HPLC Columns

Hydrophilic Polar Selectivity and Performance!The Kinetex C8 HPLC column is a core-shell-based particle with a bonded silica phase ideal for the analysis of very hydrophobic compounds. This versatile column can easily upgrade existing fully porous 5 µm and 3 µm methods to shorten run-time, increase sensitivity, and even provide greater resolution with much higher efﬁciency levels.<ul><li>Compatible with All Analytical HPLC/UHPLC Systems*</li><li>Balancing Performance &amp; Retention</li><li>USP:L7</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Kinetex_Core_Shell_C8_HPLC_Column_eb663e39df.webp" alt="Phenomenex: Kinetex Core-Shell C8 HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Kinetex_Core_Shell_C8_HPLC_Column_eb663e39df.webp 245w," sizes="100vw" width="500" height="150"><ul><li>Carbon Load: 8 (effective), 8 (effective) %</li><li>Surface Area (m²/g): 200</li><li>Particle Size (μm): 5</li><li>Recommended Use: Minimized hydrophobic retention for highly hydrophobic compounds</li></ul><h4>Balancing Speed and Retention</h4>The Kinetex core-shell C8 provides the same Kinetex performance but with a little less hydrophobic retention in comparison to the Kinetex C18 column. This C8 column is ideal for extremely hydrophobic compounds that might be too strongly retained on a traditional C18 phase column.<blockquote>Stationary phase Kinetex Core-Shell C8 is provided in these column types: analytical and preparative</blockquote>Axia Packed Preparative Columns<ul><li>Column length (mm): 50, 100, 150, 250</li><li>Column ID (mm): 21.2; 30</li><li>Particle size (µm): 5</li></ul><h3>Kinetex Core-Shell Technology Columns</h3>Kinetex Core-Shell Technology delivers dramatic improvements in efficiency over conventional fully porous media, which can be leveraged to increase resolution, significantly improve productivity, reduce solvent consumption, and decrease costs. Whether you are running high-performance liquid chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC) methods, the Kinetex core-shell family can deliver shockingly improved performance over the current column you are using. Phenomenex designs, manufactures, and sells its very own silica and organo-silica core-shell particles.Advantages of Kinetex HPLC Columns<ul><li>Performance gains on ANY liquid chromatography system</li><li>System-to-system and lab-to-lab method portability</li><li>Improve the productivity of older, established methods.</li></ul><h4>How Does Core-Shell Technology Work?</h4>Core-shell technology in chromatography is a revolutionary approach that enhances the efficiency of HPLC systems while minimizing costs. Core-shell particles are designed with a solid, non-porous silica core surrounded by a porous outer layer. This unique structure allows for faster analyte mass transfer between the mobile and stationary phases, as diffusion occurs only through the thin, porous shell rather than the entire particle. This minimizes band broadening, leading to higher separation efficiency and sharper peaks.The consistency in size and shape of core-shell particles further enhances separation efficiency by reducing variability in analyte movement. As a result, core-shell HPLC columns provide high efficiency and resolution at lower backpressures, making them an ideal choice for labs looking to improve their existing HPLC systems without the need for costly UHPLC equipment.Core-shell technology thus offers a cost-effective alternative to upgrading to UHPLC systems, enabling labs to maximize the efficiency of their current HPLC setups. The formation of these particles through advanced sol-gel processing techniques ensures uniformity and reliability, making them a valuable tool in modern chromatography. By using the Kinetex HPLC column, laboratories can achieve faster analysis times and higher productivity while maintaining excellent separation performance.<h3>Kinetex Core-Shell Performance on Any LC System</h3>The 5 versatile particle sizes allow you to select the best fit for your instrument.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_5_particle_sizes_bbed75c36f.jpg" alt="Phenomenex: Five versatile particle sizes of Kinetex Core-Shell Technology Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_5_particle_sizes_bbed75c36f.jpg 245w," sizes="100vw" width="1341" height="333"><h3>Particle Chemistry</h3>Using sol-gel processing techniques that incorporate nano-structuring technology, a durable, homogeneous porous shell is grown on a solid silica core to create a Kinetex Core-Shell particle. This particle morphology results in less band broadening for all four sources of UHPLC band broadening compared to fully porous particles and thus delivers extremely high efficiencies.<ul><li>Optimized for Ultra-High Performance</li><li>Superior Core-Shell Quality</li><li>Core-Shell Scalability and Portability</li></ul>Kinetex particles are characterized by an exceptionally consistent size distribution, with particles being nearly monodispersed, meaning they are uniform in size. This precise uniformity plays a crucial role in minimizing variability within the column, leading to enhanced separation efficiency and sharper peaks.The nearly monodispersed nature of these particles ensures that the flow of the mobile phase remains consistent, reducing the likelihood of irregularities that can impact results. As a result, Kinetex columns deliver highly reliable and reproducible performance, making them ideal for achieving consistent analytical outcomes acrLC Kinetex Core-Shell Technolooss various applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_Kinetex_Polar_C18_vs_Fully_Porous_phase_a2729b64e5.jpg" alt="Phenomenex: Kinetex Polar C18 vs Fully Porous phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_HPLC_and_UHPLC_Kinetex_Core_Shell_Technology_Columns_Kinetex_Polar_C18_vs_Fully_Porous_phase_a2729b64e5.jpg 245w," sizes="100vw" width="1376" height="581"><h3>Core-shell vs Fully Porous</h3><h4>High-Efficiency‚ High-Density Particle</h4>The combination of a consistent, solid, high-density core along with proprietary column packing technologies in the Kinetex HPLC column ensures optimum bed structure and high column performance. This carefully designed core structure promotes uniform packing of the particles, which is essential for minimizing band-broadening effects that can arise from Eddy Diffusion.The manufacturing process of Kinetex columns is tightly controlled, focusing on factors such as particle size distribution, surface and bonding homogeneity, and packing quality. This meticulous engineering leads to uniform packing and minimized band-broadening, resulting in superior separation efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Core_shell_vs_Fully_Porous_60601b6fa3.jpg" alt="Phenomenex: Core-shell vs Fully Porous.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Core_shell_vs_Fully_Porous_60601b6fa3.jpg 245w," sizes="100vw" width="904" height="506"><h3>Expand Your Core-Shell Selectivity Toolbox</h3>Kinetex core-shell particle LC columns deliver exceptional performance enhancements across any LC system, offering unmatched efficiency and resolution. With a choice of 11 diverse stationary phases, these columns cater to a wide range of chromatographic applications, ensuring optimal separation for various analytes.Additionally, the availability of five versatile particle sizes allows for precise method tailoring, enabling both high-speed and high-resolution separations. Whether you're using HPLC or UHPLC systems, Kinetex columns provide the flexibility and performance needed to achieve superior analytical results.<h3>Top 5 Pros of Kinetex Core-Shell Technology</h3><ul><li>Productivity: Kinetex Core-Shell Technology significantly enhances method productivity with minimal effort. By simply replacing traditional, fully porous columns with Kinetex HPLC columns, users can achieve better resolution, sensitivity, and overall productivity without extensive method redevelopment. This easy switch allows for immediate improvements in chromatographic performance, making it a cost-effective upgrade to existing methods.</li><li>Portability The Kinetex Core-Shell columns are available in a range of particle sizes (1.3 µm to 5 µm), which ensures method portability across different HPLC and UHPLC systems. This scalability allows for consistent retention and selectivity across various particle sizes while accommodating different backpressure levels, making it easier to transfer methods between instruments.</li><li>Performance Kinetex Core-Shell Technology delivers superior chromatographic efficiency compared to fully porous particles. This efficiency boost enables chromatographers to maximize the performance of their HPLC/UHPLC systems, ensuring optimal results with higher resolution and sharper peaks, even under similar method conditions.</li><li>Phases With 11 unique phase selectivities available, Kinetex Core-Shell Technology offers unmatched versatility for method development. This wide selection of phase chemistries allows for tailored separations and simplified optimization, ensuring the best possible results for a wide range of applications.</li><li>Pressure Kinetex Core-Shell columns provide higher efficiency at lower system backpressures compared to fully porous columns. This allows users to achieve superior chromatographic performance on conventional LC instruments without the need for ultra-high-pressure systems, making it a practical choice for routine analyses.</li></ul>

Phenomenex Gemini C8(3) HPLC Columns

Gemini C8(3) purification media is optimized for human insulin and its analogues, offering exceptional mechanical strength, high packing efficiency, and enhanced resistance to caustic regeneration conditions.

<h4>Optimized Purification Media for Human Insulin and It's Analogues</h4><ul><li>Enhanced Robustness Against Caustic Regeneration Conditions</li><li>High Packing Efficiencies</li><li>Incredible Mechanical Strength</li></ul>Typically insulin purification methodologies include vital steps for column efficiency tests, equilibration, loading, and multiple caustic washes. In particular, the high pH caustic washes are very important for the removal aggregate build up, however these wash steps typical diminish column lifetime quite substantially. With the improved chemical robustness and performance of Gemini C8(3) customers can now switch their focus to higher yields and purities and minimize operational down-time due to less frequent need to replace contaminated media.<h4>QC Tested to ensure consistent selectivity for Insulin and Impurity</h4>In conjunction with a media designed specifically for insulin purification, the Quality team at Phenomenex strives to ensure high reproducibility of Gemini 10µm C8(3) through numerous quality control steps throughout the manufacturing process, including a fit for purpose human insulin QC test. This elevated level of focus on quality ultimately results in a model product for large scale insulin purification.<h5>Key features:</h5><ul><li>Carbon Load: -</li><li>Surface Area (m²/g): -</li><li>Particle Size: 10</li><li>Recommended Use: Separation of very hydrophobic compounds</li></ul><h3>Gemini HPLC Columns</h3><h4>Twin-NX technology HPLC columns. Extend your column lifetime</h4>Gemini columns are rugged reversed-phase HPLC and PREP LC columns that offer extended lifetime at pH 1-12 conditions and excellent stability for reproducible, high-efficiency separations. The Gemini family contains a variety of useful alkyl and phenyl phases bonded to fully porous organo-silica particles.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Gemini_HPLC_Columns_936267c483.jpg" alt="Phenomenex: Gemini Twin Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Gemini_HPLC_Columns_936267c483.jpg 134w," sizes="100vw" width="349" height="405"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Gemini_HPLC_Columns_2_e67e00cc54.jpg" alt="Phenomenex: Gemini-NX Twin Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Gemini_HPLC_Columns_2_e67e00cc54.jpg 134w," sizes="100vw" width="349" height="405">Each Gemini column is supplied with a Certificate of Quality Assurance (CQA) indicating testing conditions, operating parameters, and column details.

Products from category C8 HPLC columns distributed by Phenomenex - page 1

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