Instrumentation Mini Symposium: Latest Updates in Preparative Chromatography & Amino Acid Analysis

Webinar 1: An introduction to Centrifugal Partition Chromatography (CPC): a scalable, cost effective solution for natural compounds research and production

Scientists purifying natural compounds are fast adopting Centrifugal Partition Chromatography (CPC) as a highly efficient complementary technique to HPLC and flash chromatography. With its larger injection volumes, faster flow rates, combined with high yields and purity, CPC provides a scalable, efficient and cost effective solution for purification and extraction from bench to industrial scale.

This webinar explains the basics of the technique and how it is the ideal choice for fragile molecule extraction. We will show 'real life' examples of natural product purification from milligrams to kilograms scale. With its unique properties and selectivity of liquid/liquid extraction, you’ll discover how it uses significantly less solvent than traditional methods, and eliminates column replacement and silica recycling.

Gregoire Audo is an Engineer in natural product chemistry in charge of the Centrifugal Partition Chromatography (CPC) application team and road map at Gilson. Gregoire benefits from 20 years experience developing CPC methods in all aspects, including extraction / purification of natural products, and holds a master’s degree from the University of Reims.

Webinar 2: Robust and reproducible chromatographic analysis of ammino acids using a dedicated amino acid analyser

Amino acid analysis can be used in several different fields, for example, food and beverage testing, feedstuff analysis, purity control of raw materials according to Ph. Eur. and in diagnostics. However, amino acids are demanding analytes, especially for routine analysis. The VWR Hitachi LA8080 amino acid analyser is a dedicated instrument with superior reproducibility and robustness for amino acid analysis in comparison to a normal HPLC instrument. We will show how the LA8080 works and how it differs from a standard HPLC. If you are experienced in chromatography, but not familiar with amino acid analysers, you will be surprised how complex and highly optimised methods can be. We will also have a look at official applications where amino acid analysers are applied, including Ph. Eur. monographies.

Andreas Loebers is an Application Scientist with Avantor responsible for the development and optimisation of applications relating to our VWR Hitachi HPLC instruments and amino acid analysers. Prior to his current role, Andreas was a Chromatography Sales Specialist with VWR in Germany for several years. A PhD in pharmaceutical biology from the University of Erlangen-Nuremberg, Andreas has also worked in the field of enzymatic reactions and natural products of crops. Andreas is central to supporting our Avantor customers with all aspects of their chromatography applications, and is experienced in delivering product training in many different formats including 'hands on' and virtual training.