Routine and Robust Peptide Separations Workshop
The ongoing analytical requirements of producing today's new peptide and protein therapeutics have laboratories continually pressed to attain increasing levels of performance and productivity. The development of sensitive methods that are robust, reliable and reproducible is challenging.
Non-specific adsorption of analytes when using conventional LC systems configured with stainless-steel hardware can lead to reduced sample recovery and poor peak shape.
From a regulatory perspective, method modernization and lifecycle management initiatives are aimed at facilitating industry adoption of these new technologies.
The benefits of ACQUITY PREMIER with MaxPeak HPS technology enable scientists to increase productivity in the lab and mitigate risk through increased reproducibility, recovery, and robustness of assays performed in the development and manufacturing of biopharmaceutical drug products will be demonstrated.
When peptide mass information is obtained from a simple mass spectrometer, it becomes easy and affordable to utilize mass information as part of routine peptide monitoring studies. This additional capability enables an analyst to:
- Rapidly confirm the expected mass of a peptide
- Easily monitor multiple quality attributes
- Track individual peptides over the course of peptide mapping method development
