Glycan Analysis in Biopharma: Challenges & Future Directions

Glycosylation – the addition of sugar molecules to proteins – is a post-translational modification that can profoundly influence protein structure and function. Historically, glycan analysis (or glycomics) has lagged behind genomics and proteomics in terms of prominence and technology development. This is beginning to change as a growing audience becomes aware of the criticality of protein glycosylation. With this change, biopharmaceutical researchers who understand robust and reproducible ways to analyze glycosylation in their samples can increase confidence in their results, and potentially reduce costly efforts later in the development cycle.

In this event we bring together industry leaders who will present their approaches to the challenges of glycosylation analysis, focused on biotherapeutics and biomarkers. This will include an introductory scene-setting presentation followed by an expert discussion with participants providing their insights into current trends in glycan analysis, key analytical challenges facing the industry, and future directions in the field.

By attending this educational event you will:

• hear from leading scientists on current approaches to N-glycan and sialic acid analysis
• learn about current methods for glycan analysis of biotherapeutics by liquid chromatography/ mass spectrometry (LC/MS)
• understand the challenges facing biopharmaceutical scientists in terms of both analytical quality and regulatory issues
• hear about some of the unmet needs and what is required to move this key field forwards

Why not participate in this expert discussion with industry leaders – air or submit your questions, and learn from others, on other areas of glycan analysis. You can submit your questions in advance using the registration form to the right.

Presenter: Arnaud Delobel (R&D and Innovation Director, Quality Assistance S.A.)

Presenter: Pauline Rudd (Professor at BTI AStar Singapore, GCon consultancy)

Presenter: Gordan Lauc (Founder and CEO of Genos & CSO at GlycanAge)

Presenter: Michael Butler (Principal Investigator in Cell Technology at NIBRT)

Presenter: James Duffy (Assay Development Manager - MS, LabCorp)

Moderator: Mike Claybourn (Independent Pharmaceutical Consultant)