From Liquid to Ions…. Eliminate your Fears switching from Electrospray ionization (ESI) to Atmospheric Pressure chemical Ionization (APCI)
Wait what?! Who knew!? There are so many things that a mass spec can do.
I've used it for years, yes this may be true.
I've processed some samples, more than a few.
But between me and you, I had no idea all the things it could do!
From sample prep to separation, you just won't believe…
All of the tips and tricks we have up our sleeve.
So, take a few minutes, about 15 should do.
And learn all the things your mass spec can do.
Electrospray ionization (ESI) is the most common ionization technique used in LC-MS, however not all samples are best analyzed by ESI. Atmospheric Pressure Chemical Ionization (APCI) is a complementary technique that can work well with small molecules that are more non-polar or neutral. Considerations for solvent and mobile phase additives to optimize APCI performance will be discussed.
Presenter: Emily Parry, PhD (LC/MS Applications Scientist, Agilent Technologies, Inc.)
Emily has been with Agilent for four years. Prior to joining Agilent, Emily developed methods for environmental contaminants in a variety of human and environmental matrices using both targeted and untargeted mass spectrometry techniques. She worked as a researcher at the Environmental Protection Agency (EPA) and Public Health Institute. She received her Ph.D. degree in Environmental Chemistry from the University of California, Davis.
