Expanded Screening with a Nominal Mass Tandem Quadrupole System
Expansion of the MRM Toxicology Screening Methodology for Use With Waters Xevo TQ-S micro Tandem mass spectrometry has gained popularity over the years owing to its analytical sensitivity and selectivity, especially when used in MRM mode.
MRM can be used for quantitative analysis as well as targeted qualitative screening. Broad screening techniques that can detect a wide variety of toxicants in complex biological matrices are very much in demand in forensic toxicology laboratories.
At Waters, we have provided and supported, ready-to-implement MRM based toxicology screening solutions for almost two decades.
This session will detail the further development of the popular Xevo TQ-S micro method and the expansion of the MRM Toxicology Screening Methodology which includes the addition of novel psychoactive substances (NPS) and other new drug classes.
Learning objectives – what you will learn:
- Expansion of the MRM nominal mass screening method
- How the samples were prepared and data utilized
- Total number of substances added and their drug classes
Presenter: Nayan. S. Mistry (Senior Application Scientist, Forensics, Research & Development, Waters Corporation, Waters Corporation)
Nayan Mistry is a Senior Application Scientist at Waters Corporation. Nayan joined Waters in 2009 and is part of a global team dedicated to performing research and development of applications and analytical solutions for Forensic Toxicology.
Nayan’s key focus is on toxicology screening and he has expertise with both nominal mass and accurate mass-based screening using UNIFI and Waters_Connect application software. Nayan plays a key role in the development of these solutions and in the expansion of associated libraries. Currently Nayan is playing a key role in the development and support of the recently launched Xevo G3 QTof mass spectrometer in addition to other responsibilities for the nominal mass applications. His favourite aspect of the role is customer support - Nayan is greatly involved in global on-site customer support and training and has presented his work at conferences worldwide.
