LC-MS User Meeting 2020 - Clinical Toxicology - Plenary Session

The Clinical and Forensic Toxicology laboratories are rapidly evolving as an increasing number of assays are moved to LC-MS. Toxicological screening is starving for reliable, comprehensive and always up-to-date databases to cope with the continuous appearance on the market of new psychoactive substances. Reducing the number of false positives and false negatives can significantly reduce the laboratory workload as well as improving its reputation. The opportunity to putatively identify unreported substances is also becoming a topic of increasing interest for the user. Multi-channel systems, with multiple LCs working in parallel on the same mass spectrometer taking advantage of its idle times, can dramatically improve the daily throughput. TurboFlow technology for online sample extraction can also help to overcome the bottleneck of extensive offline sample preparation. This part of the EMEA LC-MS users' meeting will interest those involved in Clinical and Forensic laboratories, focusing on target and unknown toxicological screening, quantitative confirmation and are interested in increased throughput analytical approaches.

You will learn about how high-resolution Thermo Scientific Orbitrap mass spectrometry can support both screening and quantitative approaches. You will also have a flavour of how multi-channel and TurboFlow technologies can speed up routine work in your lab.

9:00 BST (10:00 CEST - Prague) | Plenary 1 | Your fast-track to confident results in clinical toxicology: Thermo Scientific™ Orbitrap Exploris™ product family expanded

• Speaker: Thomas Moehring, Sr Director Marketing LSMS, Thermo Fisher Scientific

9:30 BST (10:30 CEST - Prague) | Plenary 2 | Novel approach for drugs of abuse screening leveraging Orbitrap Technology

• Speaker: Dr. rer. Nat Michael Boettcher, Head of toxicology department of MVZ Labor Dessau GmbH (Limbach Gruppe). , MVZ Labor Dessau

Presenter: Thomas Moehring (Sr Director Marketing LSMS, Thermo Fisher Scientific)

Dr. Thomas Moehring studied Chemistry and Environmental Science at the Carl von Ossietzky University Oldenburg, Germany, and completed his Ph.D. project at the Institute of Chemistry and Biology of Marine Environment (ICBM) Oldenburg, Germany.

He then became the Team Leader Peptidomics technology at BioVisioN (Hannover, Germany). In 2004 he joined Thermo Fisher Scientific as application/demo chemist, followed by various roles in Product Management.

Thomas is currently leading global Product Management efforts for Life Science Mass Spectrometry as Senior Director of Hardware Platform Management.

Presenter: Dr. rer. Nat Michael Boettcher (Head of toxicology department of MVZ Labor Dessau GmbH (Limbach Gruppe). , MVZ Labor Dessau)

Michael Böttcher received his diploma in zoophysiology and biochemistry at the Zoological Institute at University of Hamburg in 1987. He earned his PhD degree in 2004 at University Duisburg/Essen for lymphocyte micro-chimerism studies after liver transplantation using flow cytometry. Since 1988 he is working in private labs in the field of chromatography with special focus on drugs of abuse. Michael Böttcher is the head of toxicology department of MVZ Labor Dessau GmbH (Limbach Gruppe) which is one of the biggest drug testing labs today in Germany. The department is working in all kinds of drug and alcohol testing eg.: employee and pre-employment screening, clinical drug screening, intoxications, therapeutic drug monitoring etc. They are also performing confirmation and specialized analysis in different body fluids and hair for other labs and forensic institutes in Germany, Europe and the U.S.A. and are accredited for forensic drug testing.