LC-MS/MS Analysis of PFAS in Bovine Serum for Clinical Research Using Microelution SPE
Per- and Polyfluoroalkyl Substances (PFAS) are exceptionally versatile chemicals and have seemingly endless applications that include more than 12,000 different compounds.
Due to the persistent nature of these compounds, as well as their ability to be easily transported through the environment, there is a significant concern for the presence of PFAS in the human body. A LC-MS/MS method utilizing microelution SPE for sample cleanup, presented for analysis of seven PFAS, identified significant by National Academies of Sciences, Engineering, and Medicine for clinical research and biomonitoring in public health labs.
Who Should Attend:
- Any scientists interested in LC-MS/MS and sample preparation or anyone curious about PFAS from biological samples
Key Learning Points:
- Learn key steps to LC-MS/MS and sample preparation of biological samples
- Understand potential Challenges when extracting PFAS from biological samples
- Find advantages of using Micro elution SPE sorbent technology
Presenter: Shahana W. Huq (Senior Application Scientist, Phenomenex)
Shahana is a Senior Application Scientist focusing on emerging technologies and solutions within Clinical Research and Sample Preparation, at the Phenomenex Applications Laboratory since the year 2000. She holds an MS in Biochemistry from California State University, Los Angeles. Her work involves experimental design, analytical method development, optimization, and troubleshooting. Furthermore, she has extensive expertise in R&D product innovation and application development, as well as hands-on experience in sample preparation and LC-MS/MS. Shahana’s drive, and vision of the clinical field has motivated her to participate in various scientific publications and even as a coauthor of Phenomenex patent on sample preparation products. Currently, Shahana works closely with global customers in the applied market, providing technical support and consultation services as well as onsite seminars and webinars to promote peer development.
Presenter: Richard Jack, PhD (Global Market Development Manager, Phenomenex)
Richard is the global market development manager for the environmental and food markets at Phenomenex. He has over 18 years of experience with chromatography and mass spectrometry for the environmental, food, cannabis, semiconductor, chemical, and pharmaceutical industries. Jack has collaborated with global regulatory agencies to develop validated methods through new applications, instrumentation, column chemistries, and software. He is a former EPA scientific advisor for the EPA’s panel on hydraulic fracturing and a coauthor for EPA 557 and 557.1, ASTM D8001, and updates to D4327 and D6919 methods. He is currently the second vice chairman for the ASTM D19 subcommittee on water analysis. Previously, Jack was a vertical marketing manager with Thermo Fisher Scientific, Dionex, and Hitachi High Technologies, where he designed analytical instrumentation, including IC and HPLC systems, pumps, autosamplers, and a variety of detectors. He received his PhD in biochemistry and anaerobic microbiology from Virginia Tech in Blacksburg, Virginia. He received his master’s degree in ecology from the University of Tennessee in Knoxville.
