Introduction Non-target Screening (NTS)
The Waters 2024 Virtual Summer School - An Educational Journey to Master Food & Environmental Analysis
Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.
Why attend?
- Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.
- Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.
- Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.
Episode #3: Introduction Non-target Screening (NTS) | F&E Summer School - Day 1 - Module 3
Suspect and non-target screening (NTS) are crucial techniques used in various fields, including food analysis, environmental studies, toxicology, and doping analysis. In this overview, we’ll discuss a holistic approach and introduce high-resolution mass spectrometry methods for both Suspect and NTS screening. Topics covered include resolution, accurate mass data, and ion mobility.
In an ideal scenario, Suspect screening and non-Target screening are closely interconnected. Prior knowledge about a potential analyte (Suspect) can expedite the non-Target screening process. We’ll briefly explore Suspect screening and how high-resolution mass spectrometry offers identification criteria for confidently identifying suspect compounds.
Further, we examine the data gathered for non-target compounds through high-resolution mass spectrometry. In this module we give a concise introduction to the valuable data that can be compiled for assigning structures. In the forthcoming module 4b we will delve into how this data, in conjunction with the tools offered by the waters_connect software, can be conveniently accessed by the user and provide more comprehensive insights.
What you'll learn:
- What is Screening? (Target/ Suspect & Non-Target Screening)
- Basics of HRMS (Resolution and accurate mass)
- Identification criteria for Targets /Suspects & UNIFI Scientific Library
- Tools for Non-Target Screening
- Short introduction of exemplary instrument types
- Xevo G3 QToF for Routine Screening
- Xevo MRT for Screening with very high-resolution and very high mass accuracy
- Select Series Cyclic IMS for Screening with ion-mobility utilizing CCS-values
Presenter: Christoph Thomas (Principal Sales Applications Chemist, Waters Corporation)
Christoph Thomas is a Principal Sales Applications Chemist from the Central Europe Customer Success Team based in Eschborn, Germany. He has more than 25 years’ experience in the field of Chromatography and Mass Spectrometry and is familiar with several application areas using Quadrupole and Tof instruments. Within the last decade his projects were mainly focused on the waters_connect Screening Solution in food and environmental screening, toxicology screening, metabolite identification and in the field of extractables and leacheables.
Presenter: Gunnar Weibchen (Principal MS Sales Dev Specialist, Waters Corporation)
Gunnar studied Chemistry and obtained a PhD in Organic and Analytical Chemistry in Hamburg. After working as an Application Chemist in the demo laboratory at Varian, has been with Waters in Sales and Marketing since 2010
