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Optimize Your Polymer Analysis by Selecting the Ideal GPC/SEC Column

RECORD | Already taken place We, 20.11.2024
GPC & SEC are separation techniques often used for polymers to determine the molecular weight and molecular weight distribution.
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Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series
Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series

Choosing the appropriate column for your polymer analysis can be a challenge. Gel Permeation Chromatography (GPC) and Size Exclusion Chromatography (SEC) are separation techniques often used for polymers to determine the molecular weight and molecular weight distribution.  Whether working with organic or aqueous mobile phase conditions, there are numerous factors and criteria to consider beyond the MW range when selecting the ideal GPC or SEC column.

These include:

  • individual pore, MIXED, and multiporous packing features and benefits
  • particle and pore size considerations 
  • column chemistries and polymer sample types


Additionally, we will cover best practices for selecting solvents, choosing calibration standards, and for using columns together in series. Application examples will be given. With a diverse range of column options available, we will demonstrate how to maximize performance through your GPC/SEC column selection

Presenter: Jean Lane (Application Engineer, Agilent Technologies, Inc.)

Jean has been employed with Agilent since Nov 2010 in technical and applications support and has a primary role supporting Agilent’s full line of LC columns and consumables, which also includes support for Agilent’s GPC/SEC product line. She came to Agilent thru acquisition of Varian and the former Polymer Laboratories. Jean has 20 plus years of technical and applications support for both HPLC and GPC consumable products. In addition to practical chromatography experience in the laboratory, she has had many, many years in her technical role involving customer support providing assistance and troubleshooting for customer chromatography issues.

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