Chromatographic System Troubleshooting: A Systematic Approach
System troubleshooting can be a difficult process with a major impact on productivity. Getting a system diagnosed and repaired quickly can improve system usage and allow for work to be completed on-time with minimal out of spec results. In order to perform troubleshooting effectively, certain protocols need to be in place which can better facilitate those activities.
In this webinar, a simple and easy to follow protocol for troubleshooting LC systems will be proposed. Included will be how to set up a system performance benchmark, which will be used as a part of routine qualification checks to ensure system performance is not declining. As a part of this webinar several examples of failed chromatography and poorly performing systems will be examined and the issues therein troubleshooted.
Who Should Attend:
- People who routinely run liquid chromatography systems and need to potentially troubleshoot failed chromatograms.
- Lab managers who want to better understand how to troubleshoot LC systems to reduce system downtime and improve productivity
Learning objectives
- Implement a system monitoring protocol
- Use a system monitoring protocol to troubleshoot a failed injection
- Quickly identify failure causes and troubleshoot minor system failures
Presenter: Kenneth Berthelette (Senior Scientist, Waters Corporation Chemistry and Consumables Group)
Ken earned his Bachelor's of Science degree in Professional Chemistry from Bridgewater State University, Bridgewater Massachusetts, in 2010. He has been with Waters Corporation since March 2012 and has worked on several product launches including CORTECS columns, UPC2 Torus and Trefoil columns, and the Atlantis Premier BEH Z-HILIC column. He changed job functions in 2021 and now supports Chemistry Aftermarket initiatives. His focus on applications and customer education has led to several seminars and webinars on topics including method development, method modernization and transfer, HILIC separation techniques, and LC system troubleshooting.