From biomarker discovery to targeted assays with Stellar MS
The presentation delves into the latest advancements in mass spectrometry-based proteomics, focusing on its application in clinical settings. It outlines a workflow transitioning from proteins to peptides and back to proteins through mass spectrometry, emphasizing the importance of automated sample preparation and advanced data analysis. The speaker highlights the goal of integrating mass spectrometry into clinical practice to enable precise health assessments and personalized treatments. Case studies, such as liver disease analysis, demonstrate the superior predictive performance of proteomics over standard care tests. The presentation also discusses the development of high-throughput, targeted proteomics assays with rapid setup times, showcasing the potential of these technologies to revolutionize clinical diagnostics by providing actionable insights from biofluid samples.
Learning points :
- Clinical Application of Proteomics: Understand how mass spectrometry-based proteomics can be integrated into clinical practice for precise health assessments and personalized treatments.
- High-Throughput Assay Development: Learn about the development and rapid setup of high-throughput, targeted proteomics assays that enhance the speed and accuracy of clinical diagnostics.
- Predictive Performance in Disease Analysis: Discover the superior predictive performance of proteomics in disease analysis, exemplified by case studies such as liver disease, and how it outperforms standard care tests.
Who should attend?
- Clinical Researchers: Those focusing on integrating advanced proteomics into clinical diagnostics.
- Healthcare Professionals: Individuals interested in personalized treatments and precise health assessments.
- Biomarker Discovery Experts: Professionals involved in developing high-throughput assays for better disease prediction and analysis.
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Presenter: Maria Wahle (PhD Student, Max Planck Institute of Biochemistry)
Maria Wahle is a fourth year PhD student in the Lab of Matthias Mann in Munich. Her PhD focuses on immunopeptidomics and targeted Proteomics.
