Advanced mAb Characterization With LCMS-9050 QTOF And Byos
Discover the latest innovations in biopharma with a focus on monoclonal antibody (mAb) characterization. This session highlights how Shimadzu’s advanced LCMS-9050 Q-TOF and Protein Metrics software deliver precise analysis of complex biomolecules. Learn how high-resolution mass spectrometry (HRMS) paired with optimized data processing can effectively deliver identification and quantification of Critical Quality Attributes (CQAs) including intact mass and post-translational modifications (PTMs).
Gain actionable insights into our end-to-end workflow solution—from best practices in sample preparation to selecting the right columns and consumables—designed to optimize analytical accuracy and reproducibility. Whether in early discovery or late-stage processes, this session provides essential strategies to meet the evolving demands of mAb analysis to advance your biopharmaceutical analysis.
Learning Objectives:
- Understand the principles and applications of monoclonal antibody (mAb) characterization using Shimadzu’s Q-TOF LCMS-9050
- Explore how Protein Metrics software streamlines data processing in biopharmaceutical analysis
- Gain insights into an end-to-end workflow, covering sample preparation, column selection, and consumables to ensure reproducibility and high-quality results across all development stages
Presenter: Sheldon Gao (Customer Success Scientist, Protein Metrics)
Sheldon Gao, who holds a master’s degree from China Pharmaceutical University specializing in pharmaceutical analysis and protein racemization, has been a Customer Success Scientist at Protein Metrics since 2022. In this role, he provides technical expertise and support to customers across China and the APAC region. Prior to this, Sheldon worked at Merck, where he focused on developing LC-MS/MS methods and protein characterization. Today, he will introduce Byos, highlighting its core features and showcasing its ability to streamline protein characterization data processing efficiently.
Presenter: Shannie Tay (Senior Application Specialist (LCMS) Shimadzu (Asia Pacific) Pte Ltd)
Shannie Tay is a Senior Application Specialist at Shimadzu (Asia Pacific) Pte Ltd, bringing a wealth of experience in LCMS platforms and a strong background in the biopharmaceutical industry. Her expertise in mAb characterization, quality control, and method development has been honed through positions at leading organizations such as Nestlé NQAC, CellVec Pte Ltd, and Tychan Pte Ltd. At Nestlé R&D, she served as a subject master coach for LCMS triple quad systems, conducting ISO 17025-compliant QC tests. Later, at CellVec and Tychan, Shannie led the QC team, establishing workflows and achieving GMP certification. She authored application notes on mAb characterization, developing an end-to-end workflow with the LCMS-9050 Q-TOF, encompassing sample preparation to data analysis. Widely respected for her ability to create effective analytical workflows and deliver advanced training, Shannie has earned a solid industry reputation for her contributions to QC processes and solutions to complex issues. She will offer valuable insights in today’s discussion.
Presenter: Derrick Tan (Senior Application Chemist (Consumables) Shimadzu (Asia Pacific) Pte Ltd)
Dr Derrick obtained his PhD in Chemistry from Nanyang Technological University, Singapore.With over 7 years of extensive research experience, Dr Derrick has specialized in various areas, including small molecules, nucleic acids, peptides, and protein synthesis, as well as separation and purification techniques. He joined Shimadzu (Asia Pacific) Pte Ltd in 2021 as an Application Chemist (Consumables).In this role, he is responsible for providing technical support and application expertise for consumables in chromatography and spectroscopy. Portfolio under his care includes a wide range of products, such as LC and GC columns, UV/Vis cuvettes, sample preparation products, sample vials, and other accessories.
