Improving Sample Preparation Efficiency - The Power of Nitrogen Blowdown Evaporation
In the world of analytical chemistry, efficiency is key. As laboratories strive to enhance their sample preparation processes for GC-MS and LC-MS analyses, one technique stands out: nitrogen blowdown evaporation. This method, which uses a stream of nitrogen gas to dry down liquid samples, has revolutionized the way we concentrate samples post-extraction. Let's dive into how this process can dramatically improve your lab's efficiency, with insights from real-world case studies.
The Organomation Legacy
For 65 years, Organomation has been at the forefront of nitrogen evaporator manufacturing. The company's founder, Dr. Neal McNiven, a chemist with a mechanical bent, invented the first commercially successful multiple sample evaporator while working as a researcher at the Worcester Foundation. This innovation set the stage for the advancements we see today.
Case Studies: Real-World Impact
University of Cincinnati: From Hours to Minutes
- The Challenge: The Department of Chemical & Environmental Engineering needed to dry 10 samples at a time, each with a 5ml starting volume of methanol or acetonitrile, to complete dryness.
- The Solution: A 12-position N-EVAP nitrogen evaporator.
- The Results:
- Time reduction: From over 2 hours per sample to just 1 hour for all 10 samples
- Precision improvement: Better control of gas flow to each sample
- Enhanced sensitivity: Ability to evaporate to complete dryness with ease
University of Chicago: Longevity and Adaptability
Dr. Poorna Yalagala's research on DHA's role in brain function showcases the longevity and adaptability of Organomation's equipment:
- Used an N-EVAP for over 15 years
- Recently upgraded to a 24-sample capacity dry bath N-EVAP
- Appreciates the flexibility to fit various test tube sizes
Microbac Laboratories: Scaling Up for PFAS Analysis
- The Challenge: Need for higher sample capacity within limited benchtop space.
- The Solution: Transition from N-EVAPs to a MULTIVAP batch evaporator.
- The Benefits:
- Doubled sample capacity in the same space
- Digital features like thermostat and timer
- 400% increase in efficiency for PFAS analysis
Choosing the Right Evaporator
When selecting an evaporator, consider:
- Batch size and total sample volume
- Variety of vial sizes used
- Specific application needs
For academic settings with diverse protocols, the N-EVAP's flexibility shines. Commercial labs running consistent applications might benefit more from high-capacity batch evaporators like the MULTIVAP.
Why Partner with Organomation?
- Lifetime support at no cost
- Free virtual training for new users
- Money-back performance guarantee
- Some of the longest standard warranties in the industry
- Trusted by industry leaders like Agilent and Waters
Nitrogen blowdown evaporation is more than just a technique; it's a game-changer for laboratories seeking to optimize their sample preparation processes. Whether you're in academic research or commercial testing, the right evaporator can significantly boost your efficiency, precision, and overall productivity. As we continue to push the boundaries of analytical chemistry, tools like those provided by Organomation will undoubtedly play a crucial role in shaping the future of laboratory science.
Presenter: David Oliva (General Manager of Organomation)
One of Oliva’s favorite responsibilities is visiting academic institutions and environmental laboratories around the world. He was named to the 40 Under Forty Class of 2022 from the Worcester Business Journal and is a winner of a B2B Innovator Award from Demand Gen Report.
