Optimization of Sample Preparation for Analysis of PFAS in Serum for Clinical Research

Overview
During this presentation you will review:
- Current trends and challenges in PFAS testing for clinical research
- Key considerations for developing robust LC-MS/MS methods in biofluids
- Strategies for tailoring sample preparation to specific analyte panels
- Benefits of microelution-based sample preparation
- Comparative assessment of different sample preparation approaches
- Method optimization for handling extended, structurally diverse PFAS panels
Key Learning Points
- Identify critical factors for successful LC-MS/MS method development for PFAS analysis
- Recognize common challenges in extracting PFAS from biological matrices
- Understand the benefits and applications of microelution sorbent technology
- Evaluate how sample preparation techniques impact selectivity across diverse PFAS structures
Who Should Attend
- Any clinical, HPLC, or Sample prep users looking to learn more about PFAS testing for clinical research
Speaker: Shahana W. Huq (Senior Application Scientist)
Shahana W. Huq is a Senior Application Scientist at Phenomenex Applications Laboratory, specializing in emerging technologies and solutions for Clinical Research and Sample Preparation since 2000. She holds an M.S. in Biochemistry from California State University, Los Angeles. Shahana’s work focuses on experimental design, analytical method development, optimization, and troubleshooting. She has extensive expertise in R&D product innovation, application development, and hands-on experience in sample preparation and LC-MS/MS techniques. Her drive and vision for advancing the clinical research field have led her to contribute to many scientific publications and coauthor a Phenomenex patent on sample preparation products (2006). Currently, Shahana collaborates closely with global clinical research customers, providing technical support, consultation services, and delivering onsite seminars and webinars to foster peer development and innovation.
