Translational Proteomics
Explore how LC-MS workflows are advancing immunology research, clinical proteomics, and biomarker discovery. Learn how streamlined sample preparation and robust methods can accelerate the path from complex immune profiling to actionable insights.
Mapping immune Regulation using Mass Spectrometry-based proteomics
- David Ezra Gordon, Assistant professor and principal investigator at gordon laboratory, emory university school of medicine
The immune system operates through an interconnected network of molecular pathways, and systematically deciphering these processes is essential for advancing treatments for immune-mediated diseases and cancer. The Gordon Lab uses cutting-edge mass spectrometry–based proteomics to systematically map these molecular pathways, integrating these approaches with experimental genetics to pinpoint key nodes within the biochemical networks that govern immunity. Through scalable, high-sensitivity proteomics pipelines applied to primary immune cells both in vitro and ex vivo, our recent work has captured detailed biochemical snapshots of how immune cells respond to stimuli and adapt in pathological environments such as T cell exhaustion. Building on this foundation, we are applying genetic perturbations to dissect these signaling networks, defining the molecular nodes and pathways that drive specific immune functions. In this webinar, we will highlight studies on cytokine signaling and T cell exhaustion, and discuss how our systems-level approach to immune regulation bridges fundamental discovery with translational potential.
More SPEAKERS and talks to be announced
