Optimizing N-Nitrosamine Detection: Automated Microextraction & Machine Learning

This is the second webinar of a two-part series.

This webinar will showcase new advancements in the analysis of N-nitrosamines in pharmaceutical products. This session will emphasize the importance of sensitive analytical techniques to ensure product safety.

Key Highlights:

• Automated microextraction methods: Discover how automated microextraction methods can streamline your analytical processes
• Machine learning approaches: Learn about the integration of machine learning techniques to enhance analytical accuracy and efficiency
• Bayesian optimization: See how Bayesian optimization can significantly reduce the time and number of experiments needed for method development

With these innovations, analytical workflows become faster, more efficient, and more sustainable. Don't miss this opportunity to stay ahead in the field of pharmaceutical analysis.

Presenter: Giorgio Blom (Associate Principal Scientist, AstraZeneca)

Giorgio Blom is an Associate Principal Scientist in Trace Analysis at AstraZeneca in the UK, working in Pharmaceutical Technology and Development. He leads AstraZeneca's global Trace Analysis Expert Working Group. His work encompasses the development of novel methods to enable accurate and reliable quantitation of nitrosamines and their precursors to low parts per billion levels in drug substance, drug product, and excipients, with a focus on automation and QBD principles. As part of his role, Giorgio works with various industry groups to define best-practice procedures for trace analysis within the pharmaceutical industry and influence future practices. Giorgio obtained his degree in Chemistry with a major in Forensic Science from Avans University in the Netherlands and obtained his PhD in the field of Forensic Taphonomy.

Presenter: Amy Moore (Analytical Scientist, AstraZeneca)

Amy Moore is an Analytical Scientist at AstraZeneca, contributing to drug development projects through automated workflows, chromatography, mass spectrometry, and ICP techniques. She began with a placement year at AstraZeneca Macclesfield, where she focused on LC and GC method development, 2D NMR characterization, trace analysis, and laboratory automation. After joining Chemical Development as a graduate, Amy progressed to the Trace and Mass Spectrometry Team, expanding her expertise in robotic automation and advanced analytical technologies to improve the efficiency and accuracy of pharmaceutical analysis to low parts per billion levels across AstraZeneca's drug portfolio. Amy completed her MSci in Chemistry with a year in industry at the University of Liverpool.

Moderator: Jon Bardsley (Market Development Manager, Thermo Fisher Scientific)