Plasma Proteomics in translational medicine

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BENCHMARK OF ENRICHMENT AND DEPLETION METHODS FOR QUANTITATIVE PLASMA PROTEOMICS AND THEIR CORRELATION TO CLINICAL ROUTINE MEASUREMENT.

• Talk by Anders H. Kverneland, PhD., MD at Department of Oncology, Herlev and Gentofte Hospital, Copenhagen University Hospital

In recent years several preparatory techniques for enrichment or depletion for MS proteomics have been developed to overcome the extreme dynamic range in plasma. In this study we test and benchmark several workflows with intra- and inter-sample comparisons. In addition we test the correlaton to clinical routine protein analyte measurements performed at the hospital laboratory.