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Separation Science
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Separation Science is the leading online resource for methods, applications, troubleshooting and training in chromatography and mass spectrometry.
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Expert Answers: LC Troubleshooting and Best Practices

We, 21.1.2026 16:00 CET
Tap into expert LC guidance as Jim Grinias answers your questions on troubleshooting, method choices, and performance across workflows.
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SeparationScience: Expert Answers: LC Troubleshooting and Best Practices
SeparationScience: Expert Answers: LC Troubleshooting and Best Practices

Working with liquid chromatography (LC) brings the constant challenge to deliver clean separations and defensible data. Labs face column variability, drifting retention times, pressure spikes, ion-pairing issues, and the ongoing challenge of designing methods that hold up across instruments, sites, and sample types.

Join us for our next 'Expert Answers' session in which Jim Grinias, Professor of Chemistry at Rowan University, will tackle your LC questions. Whether you work in research, QC, or regulated environments, this session gives you space to raise the topics that matter most to your lab.

By attending this webinar, you will learn:
  • Practical ways to think through LC troubleshooting
  • Factors that influence LC performance across instruments and workflows
  • Guidance to strengthen everyday method decisions
  • Resources that help elevate routine LC work

Presenter: Dr. James Grinias (Professor, Department of Chemistry & Biochemistry, Rowan University)

James Grinias is a Professor in the Department of Chemistry & Biochemistry at Rowan University in Glassboro, New Jersey, USA. Dr. Grinias has a number of research interests focused on chemical separations and microfluidics, both at the fundamental level and for the analysis of biological systems. He is the recipient of the 2021 American Chemical Society Satinder Ahuja Award for Young Investigators in Separation Science and the 2022 LCGC Emerging Leader in Chromatography. At Rowan, he teaches courses in general, analytical, and bioanalytical chemistry while also conducting research on UHPLC column performance and instrument miniaturization.

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