Development of a Targeted Multiple Reaction Monitoring (MRM) Method for Fentalogues and Nitazene Derivatives
The growing prevalence of fentanyl analogues and nitazene derivatives presents a significant challenge for forensic and toxicology laboratories. With over 250 analogues to optimize—each associated with low sample volumes, high toxicity, and high cost—traditional workflows can be time-consuming and resource-intensive.
In this webinar, we will demonstrate how the Xevo TQ-S micro combined with QuanOptimize streamlines method development, offering practical tips and tricks for efficient optimization. We’ll also explore how PIC Scan enhances confidence in compound identification, with additional best practices to maximize reliability. Finally, discover how this approach delivers a ready-to-implement package featuring pre-configured methods and comprehensive reference data for 250 fentanyl analogues and nitazene derivatives—empowering laboratories to accelerate analysis and improve safety.
Presenter: Marco Rentsch (Principal Clinical Support Specialist, Waters Corporation)
Marco brings nearly two decades of expertise in chromatography and mass spectrometry. Since joining Waters in 2012, he has held roles focused on application support and scientific enablement. Since 2022, Marco has been a Principal Clinical Support Specialist in the European Clinical Support Team. In this capacity, Marco designs and delivers clinical solutions providing tailored training and ensures ongoing support to help customers achieve success.
