Keeping Up with Evolving Regulatory Requirements: Addressing Analytical Challenges for Known and Unknown Nitrosamines

Regulatory expectations around nitrosamines continue to evolve, placing increasing pressure on analytical workflows to deliver both accuracy and flexibility. Join our upcoming webinar with AbbVie to see how advanced LC-MS tools can help you confidently quantify known nitrosamines and uncover unknown impurities, saving valuable time and resources.

What you’ll learn:

• Confident annotation & accurate quantification: Leverage the SQUAD approach to precisely identify and quantify targeted nitrosamines using authentic standards and calibration curves.
• Simultaneous targeted & untargeted analysis: Perform comprehensive screening in a single run—detect known compounds while uncovering unexpected impurities without additional injections.
• Overcoming unknown nitrosamine challenges: Optimize your LC-MS methods to improve confidence in identifying unknown nitrosamines and meet regulatory expectations.

Presenter: Jessica Hoskins, PhD (Principal Research Scientist I, Predictive Stability and Structure Elucidation)

Jessica is a Principal Research Scientist at AbbVie where she and her team focus on Predictive Stability and Structure Elucidation to understand degradation pathways and other potential stability limiting attributes for new synthetic molecule drug substances and drug products. She has a PhD in Organic Chemistry from Tulane University with Scott Grayson, where she first became interested in mass spectrometry for polymers. Prior to joining AbbVie, she was an Adolf Martens Postdoctoral Fellow at the Federal Institute for Materials Research and Testing (BAM) in Berlin, Germany, and worked as an analytical chemist at Stepan Company in the surfactant and polymer industry.

Presenter: Sebastien Morin (Sr Manager, Business Development, Thermo Scientific)

Sebastien is a Senior Manager, Business Development at Thermo Fisher Scientific where he partners closely with Pharma and Biopharma Companies to address analytical challenges. He holds a M. SC. in Organic Chemistry from Universite de Montreal. Prior to joining Thermo Fisher Scientific, he was a Research Associate, Medicinal Chemistry for Boehringer Ingelheim, advancing virology research.