Native fluorescence detection for high-throughput CE-SDS and AAV characterization in drug development
Advancing protein and viral vector characterization requires detection strategies that deliver higher sensitivity without adding complexity to established workflows. Traditional UV detection can introduce challenges such as labelling steps, baseline drift, and lower signal‑to‑noise ratios, making it harder to resolve critical quality attributes in capillary electrophoresis–sodium dodecyl sulfate (CE‑SDS) as workflows scale and regulatory expectations increase.
In this SelectScience® TechTalk, Staff Application Scientist, Peter Holper, with 15+ years of biopharma industry experience, will demonstrate how native fluorescence detection (NFD) on the BioPhase 8800 system is raising the bar for CE-SDS analysis. By harnessing the natural fluorescence of aromatic amino acids, NFD eliminates protein labeling while delivering improved signal-to-noise ratios and cleaner baselines.
You will also discover how 8‑capillary parallel processing accelerates throughput across workflows such as CE‑SDS purity analysis and AAV capsid protein characterization, supported by real data showing accuracy and repeatability across detection modes. With streamlined sample preparation and stable baselines, your lab can get to answers faster and with greater confidence.
Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand TechTalk, you can request a certificate of attendance by emailing [email protected].
TechTalk details
- Cost: Free to attend
- Location: Online
- Duration: 20 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
This event is perfect for:
- Analytical development scientists
- Process development scientists
- CMC Directors
Speaker: Peter Holper (Staff Application Scientist, SCIEX)
Peter Holper earned his degree in Biochemistry and Cell Biology from the University of California, San Diego. He has over 15 years of experience in biopharma, including as an analytical chemist at Eli Lilly and Company where he was responsible for developing the analytical control strategy for bioproducts. Holper currently works at SCIEX where he is responsible for developing and optimizing CE applications and providing customer demo sample analysis support.
