From Downtime to Data: How Long‑Life Endrix Columns Transform High‑Throughput Labs
High‑throughput LC‑MS/MS workflows using complex matrices are often limited by column degradation, leading to poor peak shape, rising backpressure, and unplanned downtime that impact productivity and cost. Endrix LC columns address these challenges through a hardware‑driven approach, combining proven Kinetex and Luna Omega chemistries with proprietary design to extend usable column lifetime without compromising performance. Real‑world results from a 75‑analyte pain management panel demonstrate significantly increased column lifetime while maintaining consistent chromatographic integrity. By reducing column replacement frequency and minimizing troubleshooting, Endrix enables greater instrument uptime, improved efficiency, and lower cost per injection in demanding, high‑throughput workflows.
Key Learning Points
- Identify key factors that limit LC column lifetime in high‑throughput and complex‑matrix workflows
- Understand how hardware design impacts column durability, beyond stationary‑phase chemistry
- Implement strategies to extend column lifetime, reduce downtime, and lower cost per injection
- Assess when guard columns are optional and how to simplify workflows without sacrificing performance
Who Should Attend
- Any LC-MS/MS scientists in clinical, toxicology, and pharmaceutical laboratories, as well as analytical chemists working with complex or “dirty” matrices such as urine, plasma, and tissue samples.
Viewing Options
Session 1
Tuesday, July 21, 2026
- Los Angeles: 10:00 AM PT | New York: 1:00 PM EST
Mexico City: 12:00 PM CDT
Session 2
Wednesday, July 22, 2026
- London: 9:00 AM BST | Berlin: 10:00 AM CEST
Mumbai: 1:30 PM IST
Presenter: Grace Guo (Senior Technical Specialist, Phenomenex)
Grace Guo graduated from Johns Hopkins University with a Master’s degree in Material Science and Engineering. She joined Phenomenex Technical Team in 2017 providing technical support globally. With more than 9 years of experience in SPE, HPLC and GC, she delivered 90+ seminars and webinars globally covering food and environmental, clinical, pharma and biopharma industry.
