eChalk Talk: Routine Accurate Mass Detection for Forced Degradation Studies

The best way to avoid costly surprises down the road during drug manufacturing is to apply the right methodologies from the beginning, to accurately identify and control impurities during drug development. Part of this process takes place at the formulation stage, where forced degradation studies are carried out to develop analytical procedures that will be implemented in a regulated environment during manufacturing.

What are the traditional methods and techniques, both in screening and characterization? How can routine accurate mass detection with streamlined software applications be used to collect more insightful data at this stage, to shape control strategies for QC analyses, and support regulatory filings?

Presenter: Christopher Henry

Chris Henry is a Senior Scientist at Waters Corporation. For the past eight years, Chris has been working in the area of small molecule pharma solutions using LC-MS. Prior to joining Waters, Chris worked in industry for over 20 years focusing on late-stage development and QC. Chris received a degree in Biochemistry from the University of Paisley.