Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis

Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.“Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials,” said the article’s first author, David Panáček from CATRIN, who worked on the study during his internship at Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration,” said one of the corresponding authors, Michal Otyepka.The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"> CEITEC – VUT</a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.“This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,” added another corresponding author, Nuria De Diego.

Current sensors are not good enough. Scientists propose a new way to monitor plant health

In this episode of the Concentrating on Chromatography podcast, host David Oliva interviews Ainslie Chen about her cutting-edge research on hemoglobin variant testing using liquid chromatography-high resolution mass spectrometry (LC-HR-MS). Ainslie discusses her novel method for separating and identifying hemoglobin subunits with mass shifts less than 1 Da, overcoming critical limitations in conventional clinical assays.Hear firsthand how her team developed an LC-HR-MS workflow using a C4 reversed-phase column, tackled technical challenges (including why C18 columns fell short), and achieved unprecedented sensitivity for variant detection in both adult and neonatal samples. The conversation touches on the potential of mass spectrometry to revolutionize clinical diagnostics, the importance of reproducibility, barriers to adoption in routine labs, and how teamwork drives scientific innovation.Perfect for analytical chemists, clinical laboratorians, and anyone interested in the future of protein variant analysis, this episode also features Ainslie’s advice for early-career scientists and insights from her first ACS poster presentation.<h4>Key Highlights:</h4><ul><li>Motivation behind improving hemoglobinopathy testing &nbsp;</li><li>Technical advantages of LC-HR-MS over gene sequencing and CE &nbsp;</li><li>The crucial role of the C4 column in resolving challenging samples &nbsp;</li><li>Critical parameters for reproducible LC-HR-MS workflows &nbsp;</li><li>Barriers and outlook for clinical adoption of advanced mass spectrometry &nbsp;</li><li>The value of teamwork and mentorship in scientific research &nbsp;</li><li>Direct insights from recent ACS conference experiences</li></ul><h3>Video transcription</h3>In this interview, Ainslie Chen discusses her research on improving the detection and identification of hemoglobin variants using liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS). The work addresses limitations of conventional hemoglobinopathy testing, which often struggles to resolve very small mass differences between closely related hemoglobin subunits. Because even a single amino-acid substitution can significantly alter hemoglobin structure and function, high analytical resolution is essential for accurate diagnosis of conditions such as anemia and sickle cell disease.Chen explains why her team selected LC-HRMS over established clinical techniques like capillary electrophoresis and gene sequencing. While sequencing offers excellent accuracy, it is time-consuming, costly, and requires extensive sample preparation, making it impractical for routine clinical workflows. Capillary electrophoresis enables subunit separation but lacks the resolving power needed to distinguish variants differing by less than one Dalton. In contrast, high-resolution mass spectrometry provides both structural specificity and sensitivity, enabling confident identification of subtle hemoglobin variants with minimal sample preparation.A key methodological insight from the project was the use of a C4 reversed-phase LC column instead of the more common C18 column. Chen describes how the shorter carbon chain and larger pore size of C4 columns improved protein elution and reduced denaturation, leading to more reproducible separations. Critical parameters for reproducibility included consistent mobile-phase composition (0.1% formic acid in water and acetonitrile), controlled temperature (60 °C for LC, ~320 °C capillary temperature), and stable chromatographic conditions.Beyond hemoglobin analysis, Chen highlights the broader potential of high-resolution mass spectrometry in proteoform analysis and clinical diagnostics, including emerging applications in cancer detection. She acknowledges current barriers to clinical adoption—such as energy demands and instrument infrastructure—but points to advances like miniaturized mass spectrometers as promising steps toward wider use. The interview concludes with advice for young scientists: don’t hesitate to reach out to mentors, embrace collaboration, and view analytical chemistry as a versatile tool that bridges medicine, biology, environmental science, and beyond.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Unlocking Hemoglobin Variant Detection: LC-HR-MS Breakthrough with Ainslie Chen

Article

Video

Environment

Scientific article

Interview

Science and research

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

New Food magazine

Agilent Technologies

Technology Networks

Thermo Fisher Scientific

Waters Corporation

<ul>
<li>Wait what?! Who knew!? There are so many things that a mass spec can do.
</li>
<li>I&#39;ve used it for years, yes this may be true.
</li>
<li>I&#39;ve processed some samples, more than a few.
</li>
<li>But between me and you, I had no idea all the things it could do!
</li>
<li>From sample prep to separation, you just won&#39;t believe…
</li>
<li>All of the tips and tricks we have up our sleeve.
</li>
<li>So, take a few minutes, about 15 should do.
</li>
<li>And learn all the things your mass spec can do.
</li>
</ul>
In this webinar, there will be a discussion on ways to reduce the instrument background level and how to minimize compound carryover using autosampler’s cleaning parameters options. For the instrument background, step by step instructions will be provided how to clean the entire LC/MS system. For the carryover reduction, suggestions for selecting washing solvents as well as instrument settings for the autosampler settings to minimize compound carrover.
<blockquote>
Presenter: Andre Szczesniewski (Applications Chemist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Andre graduated from University of Illinois in Urbana-Champaign with a master’s degree in Food Science. Working for over 30 years in the instrumentation industry as an applications chemist, Andre has specialized in the development and implementation of LC-MS applications for various industries including clinical research. He has expert knowledge of chromatography (from nano- to preparative-scale) and mass spectrometry with extensive practical knowledge in areas of small and large molecules, quantitation, proteomics, metabolites identification, forensics, clinical, toxicology, food and environmental analysis.
</blockquote>

Agilent Technologies: Reduction of the background level and compound carryover for LC/MS applications

Reduction of the background level and compound carryover for LC/MS applications

Ways to reduce the instrument background level and how to minimize compound carryover using autosampler’s cleaning parameters options.

The background level and carryover for LC/MS applications

TBD
<blockquote>
Presenter: Mark Sartain, Ph.D. (LC/MS Applications Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mark has developed a diverse array of targeted and nontargeted mass-spectrometry based metabolomics and lipidomics applications since joining Agilent in 2012, with a focus on complete hardware/software workflows. Mark began utilizing mass spectrometry in his graduate work to characterize glycoproteins, and later established a novel LC/MS strategy to comprehensively profile and identify complex lipids of Mycobacterium tuberculosis in his postdoctoral fellowship at Colorado State University. He continued designing a wide range of MS-based techniques to measure metabolites and lipids for diverse projects as a Research Scientist at the Institute of Systems Biology (Seattle, WA) prior to joining Agilent.
</blockquote>

Agilent Technologies: Elucidating Cellular Metabolism with a Full Suite of Next-Generation Omics Tools

Elucidating Cellular Metabolism with a Full Suite of Next-Generation Omics Tools

Cellular Metabolism with a Next-Generation Omics Tools

Per- and polyfluoroalkyl substances (PFAS) pose an increasing threat to the environment, animals, and human beings due to extreme chemical stability and bioaccumulation potential. PFAS analysis is a complex problem that is best addressed with complementary targeted and non-targeted approaches. A comprehensive workflow was developed for the PFAS analysis in wastewater based on the existing EPA draft Method 1633 with additional PFAS of varying size and functional group. Strategies for sensitivity will also be discussed.
However targeted assays only cover a small fraction of PFAS. Therefore non-targeted methods and software are very important to understand the health risks of PFAS. We introduce our comprehensive software, FluoroMatch suite, which covers peak picking, annotation, homologous series detection, assigning confidence, and PFAS data visualization. We show different workflows which take advantage of Agilent&#39;s iterative exclusion approach, as well as integrate Profinder non-targeted peak picking.
<blockquote>
Presenter: Tarun Anumol, PhD (Director, Global Environment Market, Agilent Technologies, Inc.)
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<blockquote>
Tarun Anumol is the Director for Global Environment Market at for Agilent Technologies. Previously, he was an LC-MS applications scientist at Agilent, focused on developing analytical methods for trace contaminants on LC-MS/MS and LC-Q/TOF in food and environmental matrices. Tarun has a strong history of working in the environmental &amp; food testing industry, with a background in technical and applied science, with over 30 peer-reviewed journal publications in this area.
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Prior to joining Agilent, Tarun graduated with a Ph.D. in Chemical &amp; Environmental Engineering from the University of Arizona with a focus on emerging contaminant attenuation including PPCPs, PFAS and DBPs in water reuse schemes.
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Presenter: Emily Parry, PhD (LC/MS Applications Scientist, Agilent Technologies, Inc.)
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<blockquote>
Emily has been with Agilent for four years. Prior to joining Agilent, Emily developed methods for environmental contaminants in a variety of human and environmental matrices using both targeted and untargeted mass spectrometry techniques. She worked as a researcher at the Environmental Protection Agency (EPA) and Public Health Institute. She received her Ph.D. degree in Environmental Chemistry from the University of California, Davis.
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<blockquote>
Presenter: Jeremy Koelmel, PhD (Researcher at Yale University and CEO of Innovative Omics, Innovative Omics and Krystal Pollitt Laboratory, Yale University)
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Unravelling the PFAS puzzle with Comprehensive Targeted & Untargeted Workflows

PFAS analysis is a complex problem that is best addressed with complementary targeted and non-targeted approaches.

PFAS with Comprehensive Targeted & Untargeted Workflows

Focus will be given to the safety, authenticity and quality of food and beverages as well as the future of food products such as meat substitutes and alternative proteins.
This online symposium will cover:
<ul>
<li>Untargeted food analysis using different MS platforms</li>
<li>Applications of near-infrared hyperspectral imaging in food quality control</li>
<li>Applications of behavioral science in food research</li>
<li>Solid phase micro-extraction for beverage analysis</li>
<li>Challenges and opportunities in fermentation for production of alternative proteins</li>
<li>ELNs to support data management in food and beverage labs</li>
<li>Key strategies for pesticide analysis using GC-MS</li>
<li>Nutritional and toxic plant-based elemental analysis using ICP-MS</li>
</ul>
<blockquote>
Presenter: Brian Quinn, PhD (Head of Mass Spectrometry, Queen&#39;s University Belfast)
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<blockquote>
Presenter: Vincent Baeten, PhD (Scientific Director, Walloon Agricultural Research Centre)
</blockquote>
<blockquote>
Presenter: Michelle Niedziela, PhD (VP of Research &amp; Innovation, HCD Research)
</blockquote>
<blockquote>
Presenter: Erich Leitner, PhD (Professor, Graz University of Technology)
</blockquote>
<blockquote>
Presenter: Stefan Cretnik, PhD (Product Manager, PAL System)
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<blockquote>
Presenter: Theresa Liao (Content Specialist, SciNote)
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<blockquote>
Presenter: Wade Opperman (Manager of the Americas, SciNote)
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<blockquote>
Presenter: Moran Farhi, PhD (VP of Research, The Better Meat Co.)
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<blockquote>
Presenter: Liyan Xing, PhD (Senior Application Scientist, PerkinElmer)
</blockquote>
<blockquote>
Presenter: Anastasia Andrianova, PhD (GC/MS Applications Scientist, Agilent Technologies)
</blockquote>

Technology Networks: Advances in Food & Beverage Analysis 2023

Advances in Food & Beverage Analysis 2023

The third edition of this online symposium will provide industry and academic scientists with the opportunity to hear from experts from across the field.

Are strong solvent effects after QuEChERS a challenge in your LC or LC/MS analysis? Agilent Feed Injection offers a solution. Learn more about this technology and application examples from food safety in this webinar.
In recent years, QuEChERS has greatly simplified sample preparation in food safety analysis. However, downstream of QuEChERS, a strong solvent sample can cause strong solvent effects in LC and LC/MS analysis, leading to peak breakthrough and poor peak shapes, especially as the injection volume increases.
Agilent Feed Injection offers a solution to this challenge. The technique mediates the strong solvent effects by infusing the sample into the mobile phase stream. This allows you to achieve perfect peak shapes and easy peak integration without the need for additional sample preparation.
Join this webinar for a comprehensive introduction to Agilent Feed Injection from Dr. Juan Liang-Schenkelberg, Product Manager, and Dr. Edgar Naegele, Application Scientist, from Agilent. The presentation will be complemented by application examples from the field of food safety analysis.
Learning points:
<ul>
<li>Learn about common challenges in LC and LC/MS analysis following QuEChERS.
</li>
<li>Learn about Agilent Feed Injection technology and how it helps overcome these challenges.
</li>
<li>Discuss application examples from the field of food safety analysis with our expert speakers.
</li>
</ul>
<blockquote>
Presenter: Dr. Juan Liang-Schenkelberg (Strategic Product Manager at Agilent Technologies)
</blockquote>
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Juan Liang-Schenkelberg holds a PhD in biochemical engineering from the Hamburg University of Technology (TUHH) in Germany. Juan joined Agilent Technologies in 2016 as Product Manager of analytical HPLC. She is currently responsible for high-end UHPLC systems and for the food segment.
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<blockquote>
Presenter: Dr. Edgar Naegele (Application Scientist at Agilent Technologies)
</blockquote>
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Edgar Naegele holds a PhD in organic chemistry from the Karlsruhe Institute of Technology (KIT) in Germany. Edgar joined Agilent Technologies in 2001 as an Application Scientist for LC and MS. Edgar is currently focused on the application of online LC and the new Agilent 1260 Infinity II Hybrid Multisampler in the pharmaceutical and food industries.
</blockquote>

Less work, better peaks

Are strong solvent effects after QuEChERS a challenge in your LC or LC/MS analysis? Agilent Feed Injection offers a solution.

Xylazine is a non-opioid sedative, analgesic and muscle relaxant which is used in veterinary medicine and not approved for human use.
Recently there has been an increase in the number of reports of Xylazine being abused in combination with other drugs of abuse, specifically fentanyl. 
Moreover, criminal drug networks are mass-producing fake pills and falsely marketing them as prescription pills. 
It is important to be able to accurately screen these materials for commonly abused and emerging drugs and confirm the identity of the materials found. 
<ul>
<li>The first part of the webinar will describe two different techniques that can be used for screening and confirmatory analysis of a counterfeit M-30 pill; one using direct ionization MS, and the other using high resolution ToF.
</li>
<li>The second portion of the webinar will describe an alternative comprehensive confirmatory method using triple quadruple mass spectrometry to quantify each compound found in the pill.
</li>
</ul>
<blockquote>
Presenter: Emily Lee (Application Scientist, Forensics, Research &amp; Development, Waters Corporation)
</blockquote>
<blockquote>
Emily Lee is an Application Scientist at Waters Corporation. Emily is part of a global team dedicated to the development of applications and analytical solutions for Forensics and Toxicology. Emily has gained experience in the use of various Waters mass spectrometry technologies for the analysis of forensic and toxicologically relevant analytes. Prior to working at Waters, Emily has experience working in forensic toxicology laboratories, with high sample turnover and fast turnaround times. Emily was involved in many aspects of day-to-day laboratory operations including sample extraction, analysis, method development and validation, analytical troubleshooting, and reporting. Emily also gained a MSc in Forensic Science (Toxicology) at the University of Huddersfield.
</blockquote>
<blockquote>
Presenter: Jane A. Cooper (Principal Application Scientist, Forensics, Research &amp; Development, Waters Corporation)
</blockquote>
<blockquote>
Principal Application Scientist in the Forensic Toxicology section at Waters Corporation, experienced in the generation of technical marketing material to support Waters Field Marketing and Sales activities. Involved in both the preparation and delivery of presentation, illustrating developed applications using Waters technologies at seminars and conferences. Experienced in the use of Waters chromatographic and mass spectrometry technologies, associated data handling, and reporting software.
</blockquote>

Waters Corporation: Xylazine Emergence: Screening and Confirmation of an Extract from a Counterfeit M-30 Pill

Xylazine Emergence: Screening and Confirmation of an Extract from a Counterfeit M-30 Pill

Two different techniques that can be used for screening and confirmatory analysis of a counterfeit M-30 pill.

Xylazine Emergence: Screening and Confirmation of an Extract

Per- and polyfluoroalkyl substances (PFAS) are the subject of significant regulatory action around the world. PFOA and PFOS are both set to be designated as a hazardous substances and needs analytical testing’s for identification and quantitation in food, water and environment. For the purpose of developing and improving the testing of the PFAS for a wide range of monitoring and improved data quality in different matrices.
This Agilent PFAS Seminar brings basics of PFAS, regulatory overview, agilent solutions and support to establish and improve PFAS testing facility for wide scale monitoring and improved data quality in different matrices.
<ul>
<li>Regulatory Overview</li>
<li>Infrastructure requirement for critical and highly sensitive analysis (Instruments)</li>
<li>Consumables needed for reliable results (Columns &amp; Consumables)</li>
<li>Agilent Expertise and LC-TQ based workflow solutions</li>
<li>Developing and accreditation of routine and regulatory PFAS methods</li>
</ul>
<blockquote>
Presenter: Dr. Ramaprasad Ganni (Technical Support Specialist, Agilent Technologies)
</blockquote>
<blockquote>
He has 21 years of experience in the field of Chromatography and Column chemistries. Worked for Elsevier GmbH; Germany, and Millipore India Pvt, Ltd. Presently working with Agilent technologies; India, since 2008 in Chemistries and Supplies division. Responsible for Workflow solutions development, providing technical support, and trainings for various industries of Food, Pharma, Petroleum, Bio-technology. Experienced in developing applications, LC and GC column chemistries and technologies, Sample preparation techniques, method developments and troubleshooting the problems of various chromatography technologies such as LC, GC, Mass Spectrometry, GPC/SEC, and Preparative LC.
</blockquote>
<blockquote>
Presenter: Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies)
</blockquote>
<blockquote>
Prasanth joined in Agilent in 2015 as application Engineer for LC-MS/MS and has 19 years of experience in the analytical instrumentation industry, specializes in small molecule applications.Prasanth received his PhD in Environmental Science from Bharathiar University, India. He also has master’s degree in business administration from the University of Buckingham, UK. Prasanth developed many analytical methods in LC-MS/MS to quantify genotoxic impurities in drug substance and products, analysis of extractables and leachables in pharma and food packaging &amp; medical devices and Bioavailability and Bioequivalence (BA/BE) studies in clinical trials. He provided guidance in developing LC-MS workflows for impurity profiling of pharmaceuticals and metabolite identification (MetID) and quantification as a part of ADME/DMPK related studies.
</blockquote>

Agilent Technologies: PFAs Analysis - No more a challenge

PFAs Analysis - No more a challenge

This Agilent PFAS Seminar brings basics of PFAS, regulatory overview, agilent solutions and support to establish and improve PFAS testing facility.

Unlock the power of data integrity in the pharmaceutical industry for accurate results, regulatory compliance, and drug safety. Join the &quot;Nitrosamines-The LC/MS Edge&quot; webinar series, Episode 3: &quot;The Compliance Code: Cracking the Data Integrity Formula.
Gain exclusive insights from a renowned industry expert, learn real-life strategies, and discover software solutions to overcome data integrity challenges. Stay ahead in quality and compliance, optimize your data management processes, and ensure your organization&#39;s success. Don&#39;t miss this invaluable opportunity to elevate your knowledge, drive success, and become a leader in data integrity and compliance!
Secure your spot now!
What You&#39;ll Gain from the Webinar?
<ul>
<li>Master the art of data integrity to guarantee accurate and reliable results in the pharmaceutical industry.</li>
<li>Learn from real-life experiences and gain expert insights on navigating data integrity challenges and their impact.</li>
<li>Discover key strategies, best practices, and considerations to ensure data integrity and compliance in your organization.</li>
<li>Harness the power of software solutions to enhance data integrity, security, and streamline data management processes.</li>
<li>Stay updated on regulatory guidelines (USFDA 21 CFR Part 11) and best practices for effective documentation management and compliance in data integrity.</li>
</ul>
Register now to elevate your knowledge, drive success, and become a leader in data integrity and compliance!
<blockquote>
Presenter: Dr. Srinivas Reddy Maram (Chief Executive Officer, Actimus Biosciences Private Limited)
</blockquote>
<blockquote>
Dr. Srinivas Reddy Maram is a distinguished leader in the pharmaceutical industry with a rich and diverse experience spanning over two decades. Currently serving as the Chief Executive Officer of Actimus Biosciences Private Limited, he has successfully held various leadership positions, including Managing Director at Elmira Laboratories Private Limited and General Manager at Zydus Group. With a strong background in Analytical R&amp;D and Quality Assurance, Dr. Maram has made significant contributions to renowned organizations such as Suven Life Sciences Ltd., Strides, Torrent Pharmaceuticals Ltd, Biocon, and Dr. Reddy&#39;s Laboratories. His deep expertise and profound understanding of the industry make him an invaluable speaker, sharing valuable insights and knowledge in the field of pharmaceutical sciences.
</blockquote>
<blockquote>
Presenter: Venkatesh Vecham (Application Specialist - Lab Informatics, Agilent Technologies)
</blockquote>
<blockquote>
Vecham Venkatesh is an experienced professional in the analytical and pharmaceutical industry. With over 19 years of expertise, he has held various roles, including Lab Informatics Application Specialist at the Centre of Excellence in Bangalore since 2018. His extensive knowledge includes being an instructor for Agilent Chromatography Software products, such as Chemstation edition software, Ezchrom edition software, and OpenLab CDS 2.x, for a period of 4 years. Additionally, Vecham has worked closely with Informatics, CSVC, R&amp;D, and Quality Control departments as a Manager in the pharmaceutical industry. Vecham&#39;s experience includes handling audits from regulatory bodies like USFDA, MHRA, ANVISA, and TGA.
</blockquote>
<blockquote>
Presenter: Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies)
</blockquote>
<blockquote>
Prasanth is an experienced analytical instrumentation professional with a specialization in small molecule applications. Joining Agilent in 2015 as an Application Engineer for LC-MS/MS, he has 19 years of expertise in the field. Prasanth holds a Ph.D. in Environmental Science from Bharathiar University, India, and a master&#39;s degree in Business Administration from the University of Buckingham, UK. His extensive knowledge includes developing analytical methods for quantifying genotoxic impurities, analyzing extractables and leachables in pharma and food packaging, conducting bioavailability and bioequivalence studies, and more. Prasanth&#39;s proficiency extends to the analysis of phytochemicals, food residue screening, and environmental sample contaminants.
</blockquote>

Agilent Technology: Nitrosamines-The LC/MS Edge - The Compliance Code: Cracking the Data Integrity Formula

Nitrosamines-The LC/MS Edge - The Compliance Code: Cracking the Data Integrity Formula

Join the "Nitrosamines-The LC/MS Edge" webinar series, Episode 3: "The Compliance Code: Cracking the Data Integrity Formula.

Nitrosamines-The LC/MS Edge - The Compliance Code

What&#39;s the connection between nirosamine impurities and mass spectrometry?
How do you ensure your lab is ready to handle and analyze any API or formulation sample at any time?
Get answers to these questions in this The Lab Central premiere.
<blockquote>
Presenter: Preeti Bharatiya (Application Engineer LC-MS/MS, Agilent Technologies)
</blockquote>
<blockquote>
Presenter: Dr. Soma Dasgupta (Application Engineer GC/MS, Agilent Technologies)
</blockquote>

Agilent Technologies: The Nitrosamines Connection

The Nitrosamines Connection

Connection between nirosamine impurities and mass spectrometry.

The recently unveiled ultra-fast scanning <a href="https://lcms.cz/products/836">Thermo Scientific Orbitrap Astral mass spectrometer</a> is a game-changer for comprehensive proteome coverage and high-throughput biomedical applications.
In this webcast, Dr. Jesper V. Olsen of the University of Copenhagen will describe the capabilities in data-independent acquisition (DIA) mode with narrow quadrupole isolation windows in combination with short LC gradients.
<h5>Register to learn:</h5>
<ul>
<li>Benefits of narrow-window data-independent acquisition (DIA)</li>
<li>How to acquire comprehensive human proteomes within hours</li>
<li>Optimize methods for low input samples, including single cells</li>
</ul>
<blockquote>
Presenter: Jesper V. Olsen Ph.D (Novo Nordisk Foundation, Center for Protein Research, University of Copenhagen)
</blockquote>
<blockquote>
Prof. Jesper Olsen studied analytical chemistry and obtained his Ph.D. in biochemistry and molecular biology at University of Southern Denmark. He was involved in developing high-resolution MS-based proteomics. In 2012, he was promoted to vice director of Novo Nordisk Foundation for Protein Research at University of Copenhagen, and in 2014 full professor.
</blockquote>

Anatech Instruments: Faster Analysis of Human Proteomes Enabled by Narrow-Window Data-Independent Acquisition

Faster Analysis of Human Proteomes Enabled by Narrow-Window Data-Independent Acquisition

The capabilities in data-independent acquisition (DIA) mode with narrow quadrupole isolation windows in combination with short LC gradients.

LCMS webinars focusing on LC/MS - page 79