News from LabRulezLCMS Library - Week 14, 2026

<h3>We're excited to announce that <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity Chromatography Software</a> version 10.1.2 is now available!</h3>This minor update expands Clarity’s portfolio with new control modules.<h4>Newly added Instrument control modules</h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4>Updated Instrument control modules</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168">Ecom</a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328">Knauer</a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">Changelog</a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622">Clarity 10.1 release highlights</a>.Clarity can control 1000+ instruments; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls">list can be previewed here</a>.</blockquote><h4>Supported Instruments in Clarity (DataApex) — Quick Guide</h4>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via digital control (DD) and analog acquisition (A/D) using the Colibrick module.<h5>Gas Chromatographs (GC)</h5>Digital integration over LAN/RS232 (many via ICF):<ul><li>Agilent: 5890, 6890, 7890, 8860, 8890, Intuvo 9000</li><li>Shimadzu: GC-2010/2014, Nexis GC-2030</li><li>Thermo Fisher: TRACE 1300/1310</li><li>PerkinElmer: Clarus 400–690</li><li>Also supported: Dani, Ellutia, Young In Chromass, Apix, Fuli, GOW-MAC (selected models)</li></ul><blockquote>Note: Most Agilent 6890–8890 and Intuvo use LAN – ICF.</blockquote><h5>HPLC Systems</h5>Full system/module control:<ul><li>Agilent 1100–1290 Infinity II (ICF)</li><li>Shimadzu LC-10/20 and Nexera LC-40</li><li>PerkinElmer Flexar / NexSAR</li><li>Knauer Azura / BlueShadow / Smartline</li><li>Hitachi Chromaster / Primaide</li><li>Young In Chromass ChroZen series</li><li>Sykam S500–S600, Watrex Streamline, Hanon LC7000–7300</li></ul><h5>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</h5><ul><li>Pumps: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li>Detectors: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li>Column Ovens: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li>Fraction Collectors: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5>Autosamplers</h5><ul><li>Agilent GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li>Shimadzu AOC-20 / AOC-5000+, SIL-10 / SIL-20 / SIL-40 series</li><li>CTC Analytics PAL, HTA autosamplers, Spark Alias/UHPLC, Knauer AS 6.1L</li><li>PerkinElmer Flexar / NexSAR AS</li></ul><h5>Other Devices</h5><ul><li>GC×GC modulators (e.g., Charles University GC×GC Modulator)</li><li>Valves &amp; switch modules (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li>Degassers, flow monitors, managers, interfaces</li><li>LC-MS / GC-MS: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li>Balances (EA extension): Mettler Toledo, Sartorius</li></ul><h5>Analog Acquisition (Colibrick)</h5>A/D support for legacy or analog-output devices:<ul><li>GC: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li>HPLC Detectors: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li>Elemental &amp; Amino Acid Analyzers: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul>If you are interested in a DEMO VERSION, contact us!

DataApex Clarity Chromatography software 10.1.2 just released!

🎤Dan Reddy (PhD candidate in the Department of Chemistry at Queen's University and a recipient of the NSERC Vanier Canada Graduate Scholarship. He was recently named one of the top 35 early-career scientists globally in the 2025 CAS Future Leaders program.)In this episode, we interview Daniel Reddy, 2025 CAS Future Leader and PhD candidate at Queen's University, about his groundbreaking research on automated mass spectrometry and dried matrix spots (DMS).Dan's work combines computer vision, 3D printer automation, and laser micromachining to revolutionize sample preparation—reducing CO₂ emissions by 28-fold and organic solvent use by 21-fold compared to traditional methods.<h4>What You'll Learn:</h4><ul><li>How to give a mass spectrometer "sight" and "taste" using computer vision and the LMJ-SSP (Liquid Microjunction Surface Sampling Probe)</li><li>The breakthrough technology behind Surface Energy Traps (SETs) for confining liquid droplets on paper substrates</li><li>Why dried matrix spots eliminate the need for cold-chain shipping and enable analysis of blood, urine, and saliva samples via standard mail</li><li>How DIY chemists are hacking 3D printers to build cost-effective autosamplers (replacing $10K+ systems)</li><li>The role of green chemistry and systems thinking in modernizing analytical methods</li><li>Why interdisciplinary collaboration (chemistry + computer science) is critical to innovation</li></ul><h4>Key Topics:</h4><ul><li>Dried Matrix Spots (DMS) for automated sample prep</li><li>Laser-micromachined Surface Energy Traps</li><li>Direct surface sampling mass spectrometry</li><li>Sustainability in analytical chemistry</li><li>3D printer customization for laboratory automation</li><li>The importance of science communication and community outreach</li></ul><h3>Video Transcription</h3><h4>Introduction</h4>Recent advances in analytical chemistry increasingly focus on simplifying workflows, improving sustainability, and enabling automation. In this context, the work of Dan Reddy centers on the concept of “bringing mass spectrometry to life” through the integration of automated sampling, computer vision, and dried matrix spot (DMS) methodologies.The primary objective is to enable efficient and reproducible analysis of biological and liquid samples—such as blood, urine, saliva, or other solutions—by depositing them onto substrates, drying them, and extracting meaningful analytical information directly via mass spectrometry.<h4>Conceptual Framework: Enabling “Sight” and “Taste” in Mass Spectrometry</h4>A central innovation in this work is the conceptual transformation of mass spectrometry from a passive analytical tool into an active, semi-autonomous system.<ul><li>“Sight” is introduced through camera-based computer vision, allowing the system to identify predefined patterns on a substrate.</li><li>“Taste” is implemented via a liquid microjunction surface sampling probe (LMJSSP), which enables direct extraction of analytes from surfaces.</li></ul>The LMJSSP consists of two concentric capillaries forming a continuously flowing microdroplet. When brought into contact with the sample surface, this droplet facilitates localized extraction, effectively enabling direct surface analysis without traditional chromatographic separation.Combined with an automated positioning system (adapted from 3D printer mechanics), the platform can autonomously locate sampling sites and perform reproducible measurements.<h4>Dried Matrix Spots as an Analytical Platform</h4><h5>Principle and Advantages</h5>Dried matrix spots involve depositing a small volume of liquid sample onto a substrate (commonly paper), followed by drying. This approach offers several advantages:<ul><li>Reduced need for cold-chain transport</li><li>Simplified sample handling and storage</li><li>Compatibility with remote or decentralized sampling</li><li>Lower solvent consumption</li></ul>These features contribute significantly to greener analytical workflows and improved logistical efficiency.<h5>Sustainability Impact</h5>The implementation of DMS-based workflows has demonstrated:<ul><li>Up to 28-fold reduction in CO₂ emissions</li><li>Up to 21-fold reduction in organic solvent use</li></ul>These improvements arise from eliminating cold-chain logistics and minimizing solvent-intensive preparation steps.<h4>Surface Energy Traps (SCTs): Controlled Micro-Sampling Environments</h4><h5>Definition and Fabrication</h5>Surface Energy Traps (SCTs) are microstructured regions on a substrate designed to confine liquid droplets within defined boundaries.The fabrication process involves:<ol><li>Coating paper with a hydrophobic layer</li><li>Using laser ablation to selectively remove the coating in defined patterns</li><li>Creating hydrophilic circular regions (typically ~0.5 mm diameter)</li></ol>These patterned regions act as micro-wells that confine droplets spatially and prevent lateral diffusion.<h5>Analytical Benefits</h5>SCTs address key limitations of traditional dried matrix spots:<ul><li>Improved spatial confinement of analytes</li><li>Reduced diffusion variability</li><li>Enhanced reproducibility</li><li>Preconcentration effects due to controlled drying</li></ul>Additionally, the SCT diameter is smaller than the sampling probe, enabling near-complete analyte collection during surface extraction.<h4>Drying Dynamics and Analyte Distribution</h4>Traditional dried matrix spots often suffer from the “coffee-ring effect”, where analytes redistribute unevenly during drying. This leads to variability depending on sampling location.The SCT approach mitigates these effects by:<ul><li>Limiting diffusion area</li><li>Maintaining analytes near the surface</li><li>Producing more uniform analyte distribution</li></ul>Preliminary investigations (e.g., via SEM imaging) indicate improved homogeneity, although further studies are needed to fully characterize drying kinetics and their influence on signal intensity.<h4>Integration with Automated Sampling Systems</h4><h5>3D Printer-Based Positioning</h5>A key engineering innovation is the repurposing of 3D printer hardware for automated sample positioning:<ul><li>Provides cost-effective XYZ motion control</li><li>Enables programmable sampling routines</li><li>Supports integration with analytical instrumentation</li></ul>Custom software—developed in collaboration with computer engineers—allows users to define coordinates, dwell times, and sampling parameters.<h5>Computer Vision Integration</h5>The addition of computer vision enables:<ul><li>Pattern recognition (e.g., alignment markers near SCTs)</li><li>Autonomous targeting of sampling locations</li><li>Reduced operator intervention</li></ul>This transforms the system into a semi-autonomous analytical platform.<h4>Comparison with Conventional Workflows</h4>Compared to traditional LC-MS or GC-MS workflows, the presented approach offers:<div><div><figure class="table"><table><thead><tr><th>Aspect</th><th>Conventional Methods</th><th>SCT + LMJSSP Approach</th></tr></thead><tbody><tr><td>Sample prep</td><td>Multi-step, solvent-intensive</td><td>Minimal, direct surface sampling</td></tr><tr><td>Chromatography</td><td>Required</td><td>Potentially bypassed</td></tr><tr><td>Throughput</td><td>Moderate</td><td>High (automated)</td></tr><tr><td>Sustainability</td><td>Limited</td><td>Significantly improved</td></tr></tbody></table></figure></div></div>While chromatographic methods remain essential for many applications, this approach provides a complementary pathway for rapid screening and targeted analyses.<h4>Green Chemistry and Systems Thinking</h4>A notable aspect of this work is the integration of systems thinking into analytical chemistry. Inspired by engagement with organizations such as the American Chemical Society and green chemistry initiatives, the research emphasizes:<ul><li>Environmental impact reduction</li><li>Resource efficiency</li><li>Lifecycle considerations</li></ul>This perspective expands the role of analytical chemists beyond method performance to broader societal and environmental implications.<h4>Future Outlook and Applications</h4>The research is currently at an early stage but shows strong potential for:<ul><li>Decentralized diagnostics (e.g., remote blood sampling)</li><li>Environmental monitoring</li><li>High-throughput screening workflows</li><li>Field-deployable analytical systems</li></ul>Further advancements are expected in:<ul><li>Substrate engineering</li><li>Automation robustness</li><li>Integration with advanced MS platforms (e.g., triple quadrupole systems)</li></ul><h4>Conclusion</h4>The integration of dried matrix spots, surface energy traps, and automated surface sampling represents a significant step toward more sustainable, efficient, and accessible analytical workflows.By combining innovations in microfabrication, computer vision, and mass spectrometry, the work of Dan Reddy demonstrates how analytical chemistry can evolve toward smarter, greener, and more autonomous systems.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

Article

Product

Application

Video

Scientists

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

New Food magazine

Agilent Technologies

Technology Networks

SelectScience

Waters Corporation

TBD
<blockquote>
Presenter: Mark Sartain, Ph.D. (LC/MS Applications Scientist, Agilent Technologies, Inc.)
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Mark has developed a diverse array of targeted and nontargeted mass-spectrometry based metabolomics and lipidomics applications since joining Agilent in 2012, with a focus on complete hardware/software workflows. Mark began utilizing mass spectrometry in his graduate work to characterize glycoproteins, and later established a novel LC/MS strategy to comprehensively profile and identify complex lipids of Mycobacterium tuberculosis in his postdoctoral fellowship at Colorado State University. He continued designing a wide range of MS-based techniques to measure metabolites and lipids for diverse projects as a Research Scientist at the Institute of Systems Biology (Seattle, WA) prior to joining Agilent.
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Agilent Technologies: Elucidating Cellular Metabolism with a Full Suite of Next-Generation Omics Tools

Elucidating Cellular Metabolism with a Full Suite of Next-Generation Omics Tools

Cellular Metabolism with a Next-Generation Omics Tools

Focus will be given to the safety, authenticity and quality of food and beverages as well as the future of food products such as meat substitutes and alternative proteins.
This online symposium will cover:
<ul>
<li>Untargeted food analysis using different MS platforms</li>
<li>Applications of near-infrared hyperspectral imaging in food quality control</li>
<li>Applications of behavioral science in food research</li>
<li>Solid phase micro-extraction for beverage analysis</li>
<li>Challenges and opportunities in fermentation for production of alternative proteins</li>
<li>ELNs to support data management in food and beverage labs</li>
<li>Key strategies for pesticide analysis using GC-MS</li>
<li>Nutritional and toxic plant-based elemental analysis using ICP-MS</li>
</ul>
<blockquote>
Presenter: Brian Quinn, PhD (Head of Mass Spectrometry, Queen&#39;s University Belfast)
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Presenter: Vincent Baeten, PhD (Scientific Director, Walloon Agricultural Research Centre)
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Presenter: Michelle Niedziela, PhD (VP of Research &amp; Innovation, HCD Research)
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<blockquote>
Presenter: Erich Leitner, PhD (Professor, Graz University of Technology)
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Presenter: Stefan Cretnik, PhD (Product Manager, PAL System)
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<blockquote>
Presenter: Theresa Liao (Content Specialist, SciNote)
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Presenter: Wade Opperman (Manager of the Americas, SciNote)
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Presenter: Moran Farhi, PhD (VP of Research, The Better Meat Co.)
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Presenter: Liyan Xing, PhD (Senior Application Scientist, PerkinElmer)
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Presenter: Anastasia Andrianova, PhD (GC/MS Applications Scientist, Agilent Technologies)
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Technology Networks: Advances in Food & Beverage Analysis 2023

Advances in Food & Beverage Analysis 2023

The third edition of this online symposium will provide industry and academic scientists with the opportunity to hear from experts from across the field.

High resolution mass spectrometry (HRMS) has gained importance for broad screening in forensic toxicology laboratories with the emergence and constant evolution of novel psychoactive substances.
The Xevo G3 QTof from Waters is the latest generation of high performance QTof technology and includes many enhancements that improve performance and system robustness. 
Among others, ion optics have been improved to enhance the detection of labile drugs such as amphetamines resulting in significantly higher sensitivity. This presentation aims to highlight some of the developments and enhancements that have been made to the recently launched Xevo G3 QTof.
Also detailed in the presentation will be a comparison study conducted between the outgoing Xevo G2-XS QTof with the Xevo G3 QTof, by means of system setup, data generated e.g., richness of information e.g., detection accuracy and analytical sensitivity.
Learning objectives – what you will learn: 
<ul>
<li>Fundamentals of high resolution mass spectrometry</li>
<li>Enhancements made to the recently launched Xevo G3</li>
<li>QTof Comparison data discussion</li>
</ul>
<blockquote>
Presenter: Nayan. S. Mistry (Senior Application Scientist, Forensics, Research &amp; Development, Waters Corporation, Waters Corporation)
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Nayan Mistry is a Senior Application Scientist at Waters Corporation. Nayan joined Waters in 2009 and is part of a global team dedicated to performing research and development of applications and analytical solutions for Forensic Toxicology. 
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Nayan’s key focus is on toxicology screening and he has expertise with both nominal mass and accurate mass-based screening using UNIFI and Waters_Connect application software. Nayan plays a key role in the development of these solutions and in the expansion of associated libraries. Currently Nayan is playing a key role in the development and support of the recently launched Xevo G3 QTof mass spectrometer in addition to other responsibilities for the nominal mass applications. His favourite aspect of the role is customer support - Nayan is greatly involved in global on-site customer support and training and has presented his work at conferences worldwide.
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Waters Corporation: High Resolution MSE Toxicology Screening using the Waters Xevo G3 QTof

High Resolution MSE Toxicology Screening using the Waters Xevo G3 QTof

This presentation aims to highlight some of the developments and enhancements that have been made to the recently launched Xevo G3 QTof.

HR MSE Toxicology Screening using the Waters Xevo G3 QTof

Human shelterin is a six-subunit complex that binds telomeres, protects them from the DNA-damage response, and regulates the maintenance of telomeric DNA.
Although high-resolution structures have been generated for individual structured domains of shelterin subunits, the structure and stoichiometry of the full complex is unknown.
In this webinar, Dr. John Zinder, a Senior Scientist in the Structural Biology group at Odyssey Therapeutics, will discuss the purification of shelterin subcomplexes and reconstitution of the entire complex using full-length, recombinant subunits. By combining mass photometry, negative-stain electron microscopy (EM), crosslinking mass spectrometry (XLMS), AlphaFold modelling, and native mass spectrometry (MS), stoichiometries were obtained, as well as domain-scale architectures of shelterin subcomplexes.
In addition, Dr. Zinder will present data on shelterin complexes which feature extensive conformational heterogeneity, regardless of the presence of DNA substrates. He will also explain how shelterin adopts a multitude of conformations and its unusually high structural variability can be beneficial for its many functions at telomeres.
Key learning objectives
<ul>
<li>Learn how to study conformational heterogeneity using single-particle mass analysis, including mass photometry</li>
<li>Understand how modelling can aid in the characterization of highly flexible assemblies, such as shelterin</li>
<li>Discover how mass photometry, especially when combined with complementary techniques, can be a powerful tool for determining the stoichiometry of a complex as well as its compositional heterogeneity at low concentrations</li>
</ul>
Who should attend?
<ul>
<li>Anyone interested in mass photometry, the architecture of shelterin, protein complexes, protein-DNA interactions, telomere stability, structure determination, molecule prediction, homology modeling, and mass spectrometry.</li>
</ul>
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Presenter: Davide Zinder PhD (Odyssey Therapeutics)
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Dr. John Zinder is a Senior Scientist in the Structural Biology group at Odyssey Therapeutics and works in the development of novel therapeutics. He has an undergraduate degree in Chemistry from Cornell University, and a masters degree in Biochemistry from the University of Colorado. He was awarded a PhD in Chemical Biology from his research in Chris Lima’s lab at the Sloan Kettering Institute. Zinder subsequently became a Damon Runyon Postdoctoral Fellow in the de Lange and Walz labs at the Rockefeller University.
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Presenter: Lawrence Howes (SelectScience)
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Lawrence studied biological sciences at Swansea University, UK, before completing a master’s in epidemiology at the University of Bristol. As a member of the Editorial team, he now plays an integral role in shaping the content on SelectScience
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SelectScience: Architecture and Stoichiometry of Human Shelterin Using Single-Particle EM and Mass Analysis

Architecture and Stoichiometry of Human Shelterin Using Single-Particle EM and Mass Analysis

Purification of shelterin subcomplexes and reconstitution of the entire complex using full-length, recombinant subunits.

Architecture and Stoichiometry of Human Shelterin

Join our panel of PFAS experts from across the food and environmental testing arena as we discuss challenges, best practices, solutions, and the future of analyzing these “forever” chemicals. Exploring the global implications of PFAS testing and ever updating regulatory requirements, hear our experts share their experiences and insights. Be sure to engage in the discussion and overcome your analytical challenges by posting your questions to our panel.
Key learning objectives
<ul>
<li>Key considerations in uncovering the right workflow- from sample preparation, detection and quantification- to achieve quality data you can trust now, and into the future.
</li>
<li>Best practices and tips in maintaining reliable and repeatable analysis in the routine laboratory workspace.
</li>
<li>Comprehensive analytical solutions to meet your laboratory’s demands, increase capacity and outperform even the most stringent of PFAS limits currently in place, US EPA Health Advisory Limits.
</li>
</ul>
Who should attend?
Lab Managers, Quality Managers, Technical Managers, Chief Scientific Officers, Lead Scientists who wish to improve their confidence, capabilities and capacity in PFAS testing.
<blockquote>
Presenter: Dr. Kari Organtini (Waters Corporation)
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Dr. Kari Organtini is part of the food and environmental applications team at Waters, developing applications on LC- and GC- MS/MS for a variety of applications ranging from pesticides to persistent organic pollutants. She is currently the scientific lead for developing PFAS applications. She received her PhD from Penn State University in 2015 where she studied the occurrence of dioxins and furans in fire debris and their implications to first responder health.
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Presenter: Dr. Stuart Adams (Waters Corporation)
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Dr. Stuart Adams has been developing methods for the determination of contaminants in food and the environment for over 17 years. Before he moved to Waters in 2018 to focus on application development, he previously worked as a senior analytical chemist at Fera. He now works with customers to understand and help address their analytical challenges with Waters technologies, with a particular interest in PFAS.
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Presenter: Stuart Oehrle (Waters Corporation)
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Stuart Oehrle is a field chemist with over 30 years of tenure at Waters and an adjunct instructor for 25+ years at Northern Kentucky University. Stuart obtained his chemistry degree from Northern Kentucky University and did his graduate work at the University of Alabama-Huntsville and University of Cincinnati. Stuart’s primary area of focus is the application of LC and LC-MS/MS. He has worked extensively in the analyses of toxins from cyanobacteria, explosives, and chemical warfare agents. He has published or presented over 70 papers as well as been awarded several patents.
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Presenter: Dr. Nicole Riddell (Wellington)
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Nicole is the Quality Manager at Wellington Laboratories Inc. She obtained a PhD in Analytical Chemistry from Orebro University (Sweden) under the supervision of Dr. Bert van Bavel and a Master’s degree in Synthetic Organic Chemistry from the University of Guelph (Canada). Her main responsibilities include Quality Management in support of Wellington’s three ISO accreditations, provision of technical support relating to the use of Wellington’s certified reference standards, and general research project co-ordination. Her multi-disciplinary background allows her to execute these tasks with a unique perspective. Although Nicole provides support for all Wellington product lines she has worked heavily with per- and polyfluoroalkyl substances (PFAS), in both a synthetic and analytical capacity, since she started at Wellington nearly 18 years ago.
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Presenter: Ken Rosnack (Waters Corporation)
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Ken Rosnack is a Principal Market Development Manager in the Testing &amp; Lab Services Group for Waters Corporation. His primary focus is within regulated and routine LC-MS/MS environmental market where he is responsible for world-wide strategy implementation and performance. He maintains collaborations within regulatory agencies as well as with global industrial partners. Over his career, Ken has been primary author on numerous publications, been an invited speaker multi-nationally, and has presented at many conferences. He has been involved with MS for the past 40 years.
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<blockquote>
Presenter: Blake Forman (SelectScience)
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Blake studied chemistry at the University of Surrey, UK, and further went on to study a master’s in chemistry at the University of Southampton, UK. Blake has previously worked in the Medicines and Healthcare Products Regulatory Agency (MHRA) lab at LGC and as a technical sales specialist for Waters. As a member of the Editorial team, he now plays an integral role in shaping the content on SelectScience.
</blockquote>

Waters Corporation: The highs and lows PFAS testing: An expert panel discussion

The highs and lows PFAS testing: An expert panel discussion

Exploring the global implications of PFAS testing and ever updating regulatory requirements, hear our experts share their experiences and insights.

Adsorption, distribution, metabolism and excretion (ADME) profiling is used to determine the properties of drug candidates. Modern drug discovery environments depend on the accuracy and precision of results from ADME studies to select new targets with a high potential for clinical success.
However, as technology advances, the size of compound libraries increases. Once a compound shows an affinity for a target, understanding the ADME profile of a drug in vitro can reduce attrition rates in the drug development process.
Acoustic ejection mass spectrometry (AEMS) has a significantly higher throughput than traditional LC-MS approaches due to the rapid sampling and flow injection analysis enabled by a high-sensitivity mass spectrometer.
In the webinar, we discuss a suite of metabolic stability assays developed using an AEMS system.
Attend this webinar to: 
Learn about how the Echo® MS system can be used in drug discovery 
Hear about the advantages of AEMS 
Discover the fundamentals of Echo® MS operation and how it can benefit your research
<blockquote>
Presenter: Dr. Jacob W. McCabe (Senior Scientist Echo® MS Center of Excellence, SCIEX)
</blockquote>

Technology Networks: Discover New Ways To Increase Your Throughput for Metabolic Stability Assays

Discover New Ways To Increase Your Throughput for Metabolic Stability Assays

In the webinar, we discuss a suite of metabolic stability assays developed using an AEMS system.

Increase Your Throughput for Metabolic Stability Assays

Are strong solvent effects after QuEChERS a challenge in your LC or LC/MS analysis? Agilent Feed Injection offers a solution. Learn more about this technology and application examples from food safety in this webinar.
In recent years, QuEChERS has greatly simplified sample preparation in food safety analysis. However, downstream of QuEChERS, a strong solvent sample can cause strong solvent effects in LC and LC/MS analysis, leading to peak breakthrough and poor peak shapes, especially as the injection volume increases.
Agilent Feed Injection offers a solution to this challenge. The technique mediates the strong solvent effects by infusing the sample into the mobile phase stream. This allows you to achieve perfect peak shapes and easy peak integration without the need for additional sample preparation.
Join this webinar for a comprehensive introduction to Agilent Feed Injection from Dr. Juan Liang-Schenkelberg, Product Manager, and Dr. Edgar Naegele, Application Scientist, from Agilent. The presentation will be complemented by application examples from the field of food safety analysis.
Learning points:
<ul>
<li>Learn about common challenges in LC and LC/MS analysis following QuEChERS.
</li>
<li>Learn about Agilent Feed Injection technology and how it helps overcome these challenges.
</li>
<li>Discuss application examples from the field of food safety analysis with our expert speakers.
</li>
</ul>
<blockquote>
Presenter: Dr. Juan Liang-Schenkelberg (Strategic Product Manager at Agilent Technologies)
</blockquote>
<blockquote>
Juan Liang-Schenkelberg holds a PhD in biochemical engineering from the Hamburg University of Technology (TUHH) in Germany. Juan joined Agilent Technologies in 2016 as Product Manager of analytical HPLC. She is currently responsible for high-end UHPLC systems and for the food segment.
</blockquote>
<blockquote>
Presenter: Dr. Edgar Naegele (Application Scientist at Agilent Technologies)
</blockquote>
<blockquote>
Edgar Naegele holds a PhD in organic chemistry from the Karlsruhe Institute of Technology (KIT) in Germany. Edgar joined Agilent Technologies in 2001 as an Application Scientist for LC and MS. Edgar is currently focused on the application of online LC and the new Agilent 1260 Infinity II Hybrid Multisampler in the pharmaceutical and food industries.
</blockquote>

Less work, better peaks

Are strong solvent effects after QuEChERS a challenge in your LC or LC/MS analysis? Agilent Feed Injection offers a solution.

Per- and polyfluoroalkyl substances (PFAS) are the subject of significant regulatory action around the world. PFOA and PFOS are both set to be designated as a hazardous substances and needs analytical testing’s for identification and quantitation in food, water and environment. For the purpose of developing and improving the testing of the PFAS for a wide range of monitoring and improved data quality in different matrices.
This Agilent PFAS Seminar brings basics of PFAS, regulatory overview, agilent solutions and support to establish and improve PFAS testing facility for wide scale monitoring and improved data quality in different matrices.
<ul>
<li>Regulatory Overview</li>
<li>Infrastructure requirement for critical and highly sensitive analysis (Instruments)</li>
<li>Consumables needed for reliable results (Columns &amp; Consumables)</li>
<li>Agilent Expertise and LC-TQ based workflow solutions</li>
<li>Developing and accreditation of routine and regulatory PFAS methods</li>
</ul>
<blockquote>
Presenter: Dr. Ramaprasad Ganni (Technical Support Specialist, Agilent Technologies)
</blockquote>
<blockquote>
He has 21 years of experience in the field of Chromatography and Column chemistries. Worked for Elsevier GmbH; Germany, and Millipore India Pvt, Ltd. Presently working with Agilent technologies; India, since 2008 in Chemistries and Supplies division. Responsible for Workflow solutions development, providing technical support, and trainings for various industries of Food, Pharma, Petroleum, Bio-technology. Experienced in developing applications, LC and GC column chemistries and technologies, Sample preparation techniques, method developments and troubleshooting the problems of various chromatography technologies such as LC, GC, Mass Spectrometry, GPC/SEC, and Preparative LC.
</blockquote>
<blockquote>
Presenter: Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies)
</blockquote>
<blockquote>
Prasanth joined in Agilent in 2015 as application Engineer for LC-MS/MS and has 19 years of experience in the analytical instrumentation industry, specializes in small molecule applications.Prasanth received his PhD in Environmental Science from Bharathiar University, India. He also has master’s degree in business administration from the University of Buckingham, UK. Prasanth developed many analytical methods in LC-MS/MS to quantify genotoxic impurities in drug substance and products, analysis of extractables and leachables in pharma and food packaging &amp; medical devices and Bioavailability and Bioequivalence (BA/BE) studies in clinical trials. He provided guidance in developing LC-MS workflows for impurity profiling of pharmaceuticals and metabolite identification (MetID) and quantification as a part of ADME/DMPK related studies.
</blockquote>

Agilent Technologies: PFAs Analysis - No more a challenge

PFAs Analysis - No more a challenge

This Agilent PFAS Seminar brings basics of PFAS, regulatory overview, agilent solutions and support to establish and improve PFAS testing facility.

Polar pesticides are the talk of the town.
And we are here to encounter them and provide a breakthrough LC/MS/MS solution to address the challenges associated with them. Attend this The Lab Central premiere to find out more.
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Presenter: Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies)
</blockquote>

Agilent Technologies: The Encounter: Polar Pesticides and LC/MS

The Encounter: Polar Pesticides and LC/MS

We are here to encounter them and provide a breakthrough LC/MS/MS solution to address the challenges associated with polar Pesticides.

Polar Pesticides and LC/MS

What&#39;s the connection between nirosamine impurities and mass spectrometry?
How do you ensure your lab is ready to handle and analyze any API or formulation sample at any time?
Get answers to these questions in this The Lab Central premiere.
<blockquote>
Presenter: Preeti Bharatiya (Application Engineer LC-MS/MS, Agilent Technologies)
</blockquote>
<blockquote>
Presenter: Dr. Soma Dasgupta (Application Engineer GC/MS, Agilent Technologies)
</blockquote>

LCMS webinars focusing on LC/MS - page 83