<h3>Introduction</h3>MOSH and MOAH analysis remains one of the most challenging and closely scrutinized areas in food and packaging safety testing. With evolving regulations, updated standards such as ISO 20122:2024, and increasing expectations for data quality and throughput, laboratories are under constant pressure to deliver accurate, reproducible, and compliant results.To help laboratories navigate this complexity, Thermo Fisher Scientific and SampleQ hosted an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5817">Ask the Experts</a> session focused entirely on MOSH/MOAH analysis using LC-GC-FID and GC×GC-FID/MS workflows. Analytical specialists addressed real-world questions from scientists and lab managers—covering sample preparation, quality control, internal standards, data processing, and system selection.This blog brings together the most important expert insights and practical guidance from that session, providing a valuable reference for anyone responsible for MOSH/MOAH testing.<h3>Why MOSH/MOAH analysis is so challenging</h3>Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) are complex mixtures rather than single compounds. Their broad carbon number distribution, co-elution with natural matrix components, and sensitivity to sample preparation steps make analysis technically demanding.At the same time, regulatory scrutiny continues to increase, particularly for MOAH due to potential carcinogenicity. Laboratories must therefore balance:<ul><li>Regulatory compliance</li><li>Robust quantification</li><li>Reliable identification of markers</li><li>High sample throughput</li></ul>The Ask the Experts session focused on how modern, integrated workflows can help labs meet all these demands.<h3>Are MOSH/MOAH sample preparation steps matrix dependent?</h3>One of the most common questions from laboratories is whether MOSH/MOAH sample preparation can be standardized across all matrices.The expert answer: it depends on the matrix—and validation is essential.For fats and oils, certain steps are always required:<ul><li>Saponification</li><li>Epoxidation</li></ul>However, alumina (Alox) clean-up is matrix dependent. Practical comparisons show that:<ul><li>Some matrices benefit from Alox clean-up</li><li>Others may suffer from analyte loss if Alox is applied unnecessarily</li></ul>For non-fat matrices, sample preparation must be carefully selected, and method validation is critical to ensure accuracy and recovery.Key takeaway: There is no universal sample prep recipe for MOSH/MOAH. Laboratories must adapt workflows to their matrices while staying aligned with ISO 20122 guidance.<h3>Managing multiple sample prep options in a busy lab</h3>Many labs analyze a wide variety of matrices daily. Running different sample prep workflows manually can be time-consuming and error-prone.Experts highlighted how software-driven workflows help solve this challenge:<ul><li>Multiple sample prep methods can run in the same sequence</li><li>Optional steps (such as Alox clean-up) can be toggled per sample</li><li>Overlapping methods maximize instrument utilization</li><li>Analysts only need to weigh samples and load reagents—automation handles the rest</li></ul>E-workflows simplify method selection and ensure the correct prep is applied every time, reducing training requirements and minimizing human error.For lab managers, this translates into:<ul><li>Higher throughput</li><li>More consistent results</li><li>Less hands-on time for skilled analysts</li></ul><h3>Which internal standard is best for MOAH quantification?</h3>Internal standard selection is critical for reliable MOAH quantification. The experts addressed this directly, referencing extensive comparative studies.Three candidates were evaluated:<ul><li>1-Methylnaphthalene (1-MN)</li><li>2-Methylnaphthalene (2-MN)</li><li>Tert-butylbenzene (TBB)</li></ul>Based on repeatability, reproducibility, recovery, and accuracy, TBB emerged as the clear winner and is now specified in ISO 20122.<h3>Why TBB?</h3><ul><li>More stable behavior across sample prep steps</li><li>Better overall performance in routine analysis</li><li>Improved consistency between laboratories</li></ul>For labs updating or validating MOSH/MOAH methods, aligning internal standards with ISO recommendations is strongly advised.<h3>How should ISO criteria for internal standard recovery be interpreted?</h3>A frequent point of confusion is how to interpret internal standard recovery limits defined in ISO methods.The experts clarified an important distinction:<ul><li>Recovery criteria apply to direct injections of internal standards</li><li>All components should fall within 90–110% of the quantification standard</li><li>Perylene is allowed a slightly broader range (80–100%)</li></ul>In real samples, internal standard recoveries can vary due to legitimate chemical effects:<ul><li>Epoxidation may reduce perylene</li><li>Alox clean-up can reduce cholestane</li><li>Saponification may affect methylnaphthalenes</li><li>Some hydrocarbons may be naturally present in the matrix</li></ul>Bottom line: Deviations in sample recoveries do not automatically indicate method failure. Understanding the chemistry behind each step is key to correct interpretation.<h3>Do you still need LC-GC-FID if you have GC×GC-MS?</h3>As GC×GC-MS becomes more accessible, many labs ask whether it can replace LC-GC-FID entirely.According to current EURL guidance:<ul><li>GC×GC is primarily intended for identification, not quantification</li><li>Quantification using GC×GC-FID is technically possible but not yet recommended</li><li>LC-GC-FID remains the reference technique for MOSH/MOAH quantification</li></ul>GC×GC-MS plays a complementary role by:<ul><li>Confirming the presence of aromatic markers and MOSH markers like hopanes, steranes and particular naphthenes</li><li>Differentiating mineral oil components from biogenic interferences</li><li>Supporting risk assessment and regulatory discussions</li></ul>For now, the most robust approach is a combined workflow:<ul><li>LC-GC-FID for quantification</li><li>GC×GC-FID/MS for confirmation and identification</li></ul><h3>Using specific ion masses for marker identification in GC×GC</h3>GC×GC-MS offers powerful identification capabilities when used correctly.Experts highlighted that:<ul><li>The EURL provides recommended ion masses for key MOAH subgroups</li><li>Selective ion chromatograms (SICs) can be generated for markers such as:<ul><li>Naphthalenes</li><li>Hopanes</li><li>Steranes</li><li>DIPNs</li></ul></li></ul>Using multiple SIC views alongside total ion chromatograms (TICs) allows:<ul><li>Faster confirmation of markers</li><li>Clear differentiation from interferences</li><li>More confident reporting of MOAH presence</li></ul>This approach significantly improves interpretability compared to relying on TICs alone.<h3>How is GC×GC-MS data processed efficiently?</h3>One concern with GC×GC-MS is the perceived complexity of data handling.The experts demonstrated a streamlined workflow:<ul><li>Instrument control and acquisition remain in <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76">Chromeleon S/W</a></li><li>Raw data are automatically exported for GC×GC processing</li><li>Templates are applied to identify known marker regions</li><li>Results are organized by vial, run, and detector channel</li></ul>This structured approach ensures:<ul><li>Consistent marker identification</li><li>Reduced manual data handling</li><li>Faster reporting despite large data volumes</li></ul>For labs new to GC×GC, standardized templates and automated processing significantly reduce the learning curve.<h3>Comparing FID and MS chromatograms: why it matters</h3>Accurate comparison between FID and MS data is critical when combining quantification and identification.Thanks to synchronized acquisition:<ul><li>FID and MS chromatograms are recorded simultaneously</li><li>First-dimension retention times are identical</li><li>Second-dimension alignment is highly accurate</li></ul>This enables:<ul><li>Direct correlation of quantified FID regions with identified MS markers</li><li>Greater confidence in results</li><li>Stronger defensibility during audits and regulatory review</li></ul><h3>Why use a single quadrupole MS instead of TOF-MS?</h3>Time-of-flight MS is often associated with GC×GC due to its high scan speed. However, experts explained why <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products?category=19&amp;manufacturerItems=3">single quadrupole MS </a>can be a practical alternative.By optimizing scan speed:<ul><li>Single quadrupole MS can capture sufficient data points</li><li>Complexity and cost are reduced</li><li>Compliance with EURL guidance is maintained</li></ul>For many routine MOSH/MOAH applications, this offers an excellent balance between performance and operational efficiency.<h3>Is offline sample preparation better for GC×GC?</h3>There is no universal answer—workflow design depends on laboratory needs.Integrated systems offer:<ul><li>Minimal user intervention</li><li>Reduced risk of contamination</li><li>Streamlined operation</li></ul>Separate systems allow:<ul><li>Parallel operation</li><li>Higher overall throughput in some labs</li></ul>The best choice depends on sample volume, staffing, and analytical priorities.<h3>Final thoughts: Building a future-proof MOSH/MOAH workflow</h3>MOSH/MOAH analysis is evolving rapidly, but some principles remain constant:<ul><li>Robust quantification still relies on LC-GC-FID</li><li>GC×GC-FID/MS adds critical confirmation power</li><li>Automation and software workflows reduce complexity</li><li>Alignment with ISO and EURL guidance ensures defensibility</li></ul>By combining expert knowledge with integrated technology, laboratories can confidently meet today’s regulatory requirements—while preparing for what comes next.If you’re looking to optimize or future-proof your MOSH/MOAH analysis, the insights from this Ask the Experts session provide a strong foundation for success.<ul><li>Watch the free webinar on demand: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5817">Talk to an expert about our barrier-free analysis of MOSH/MOAH</a></li><li>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#automation #MOSH/MOAH</li></ul><blockquote><h4>Petra Gerhards</h4>Petra Gerhards, Dipl-Ing, is Regional Marketing Manager of GC and GC-MS for EMEA at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS. She works with KOL's on data for regional specific marketing campaigns, organizes in-house seminars and works on customer specific solutions. Her main expertise is in the field of doping and drugs-of-abuse analysis.</blockquote>

Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions

Researchers planning to present their work at ISC 2026 now have additional time to submit oral presentation abstracts. The deadline has been officially extended to 18 March 2026, providing authors with a valuable opportunity to refine their submissions and secure a place in the scientific programme. Abstracts must be submitted via the online portal and will undergo evaluation by the Scientific Committee based on formal criteria and scientific merit. Poster and late-breaking submission deadlines remain unchanged.<h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a>Submit your abstract by 18 March 2026.&nbsp;</blockquote><h4>GENERAL INFORMATION &amp; DEADLINES&nbsp;</h4><ul><li>Abstracts must be submitted electronically via the Online Portal.</li><li>The abstract submission deadlines depend on the authors’ presentation preference and are as follows:<ul><li>Oral Presentation: 18 March 2026 (extended)</li><li>Poster Presentation: 1 June 2026</li><li>Late-Breaking Poster: 30 July 2026</li></ul></li></ul>The submitted abstracts can be modified until 18 March 2026 for oral presentations and 1 June 2026 for poster presentations to be included in the preliminary program. After the submission deadlines, all abstracts will automatically be considered final.Abstracts received by e-mail or after the deadlines will not be considered for the ISC 2026 Symposium.<ul><li>Abstracts must be submitted under one of the designated scientific topics, categorized into three parallel program tracks.</li><li>The abstracts with oral presentation preference will be reviewed by the ISC 2026 Scientific Committee, which will assess both their formal aspects and scientific content. The abstracts with poster preference will be reviewed by the Local Organising Committee, which will decide which abstracts are accepted and may reconsider the final presentation type if necessary.</li><li>All presenting authors who selected the oral presentation preference will receive an acceptance or rejection notification via e-mail by 21 April 2026. Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.&nbsp; All the other abstracts with poster preference submitted after 5 May 2026 will be notified of the outcome by 16 June 2026, and by 11 August 2026 for late-breaking poster presentations.</li><li>Accepted and registered abstracts will be published in the Abstract Book. Please ensure that your abstract has been carefully checked for correct spelling, punctuation, grammar, and formal structure. Authors are fully responsible for the abstract content. The organizer reserves the right to edit the accepted abstracts prior to publication if necessary. Please note that late-breaking posters will not be included in the electronic Abstract Book.</li><li>All oral presenting authors are required to register by 15 May 2026. Any oral presentation whose presenting author is not registered by this date will be withdrawn from the program. The author registration deadline is 30 June 2026 for accepted poster authors and 18 August 2026 for accepted late-breaking poster authors.</li><li>The number of abstracts submitted per presenting author is limited to one. Once the submission is completed, the system will not allow additional abstracts to be submitted. You may be listed as a co-author on other abstracts but not as the presenting author.</li><li>Submission of an abstract constitutes a commitment to attend the symposium or to send a qualified substitute who is capable of presenting the work and answering related questions.</li><li>An invitation to submit an abstract does not constitute an offer to cover travel, accommodation, or registration expenses associated with the symposium.</li></ul><h4>ABSTRACT FORMATTING GUIDELINES</h4><ul><li>All abstracts must be written in English.</li><li>A preferred presentation type must be selected during submission from the following options:<ul><li>Oral Presentation</li><li>Oral Presentation or Poster Presentation</li><li>Poster Presentation</li></ul></li><li>The abstract title is limited to 180 characters and must use Sentence case – capitalizing only the first word and any proper nouns, while keeping all other words in lowercase (e.g., This is the title of my abstract).</li><li>Up to 16 authors may be listed for one abstract (including the presenting author).</li><li>The first author listed is considered the main author.</li><li>The abstract text must not exceed 400 words.</li><li>Figures or images are not permitted in the abstract text.</li><li>Adding references is optional. If you wish to include references in your abstract, please note that they count toward the abstract word limit, and you are requested to use the following citation style (see example):<ul><li>[1] J. van der Geer, T. Handgraaf, R.A. Lupton, J. Sci. Commun. 163 (2020) 51 – 59.</li></ul></li></ul>

ISC 2026 Deadline for abstract submission extended to 18 March 2026

Dear business partner,Analytica 2026 is the world’s leading trade fair for laboratory technology, analysis and biotechnology, bringing together global experts, innovative technologies, and the latest solutions shaping the future of scientific research and laboratories.This international event is fast approaching at the Munich Exhibition Center, and we would be delighted to meet you in person in Munich.Our sales representatives will be available to discuss current challenges, opportunities, and new developments related to <a target="_blank" rel="noopener noreferrer" href="https://www.analytika.net/reference-materials-en/">Reference Materials</a> on the market.<blockquote>Hall A2, Booth 326</blockquote>Our portfolio includes a wide range of Certified Reference Materials and Reference Materials for laboratories analyzing various elements and molecules across fields such as petrochemistry, cosmetics, pharmaceuticals, toxicology, water management, and metallurgy. All standards comply with EN ISO 17034 and are suitable for laboratories accredited under EN ISO/IEC 17025. We also offer custom-made reference materials that can be configured using our solution configurator.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ANALYTIKA_Astasol_21eb1781d0.jpg" alt="ANALYTIKA: Certified Reference Materials" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ANALYTIKA_Astasol_21eb1781d0.jpg 156w," sizes="100vw" width="1200" height="1200">The pHanal™ Certified Reference Materials are designed for the calibration of pH measuring instruments and for the validation and verification of analytical methods for pH determination. They are produced using accredited procedures within the scope of accreditation according to EN ISO 17034. The pH value and its associated uncertainty are assigned based on gravimetric preparation. The solutions are also available in a color-coded version for easier identification and handling.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ANALYTIKA_p_Hanal_28a25799f7.jpg" alt="ANALYTIKA: pHanal™ Certified Reference Materials" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ANALYTIKA_p_Hanal_28a25799f7.jpg 233w," sizes="100vw" width="1199" height="800">Our portfolio also includes Matrix Certified Reference Materials with inorganic or organic content, such as strawberry leaves, green tea, soils, and sewage sludge. In addition, we offer Matrix Reference Materials for quality control, education, and experimental purposes, combining high quality with cost-effective pricing.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ANALYTIKA_CRM_8b91d9984a.jpg" alt="ANALYTIKA: Matrix Certified Reference Materials" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ANALYTIKA_CRM_8b91d9984a.jpg 245w," sizes="100vw" width="1199" height="674"><h4>We will be delighted to discuss how to:</h4><ul><li>Strengthen our partnership through personal exchange and open communication</li><li>Share insights on market developments and customer feedback</li><li>Discuss ongoing cooperation and identifying areas for mutual improvement</li><li>Explore new opportunities to support each other more effectively</li></ul>If you plan to attend and would like to schedule a meeting, <a href="sales@analytika.net">please let us know</a>. We will be happy to arrange a suitable time and provide you with a complimentary free single‑day ticket.We're looking forward to your visit!

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

New Food magazine

Agilent Technologies

Technology Networks

Bruker

SelectScience

SCIEX

Waters Corporation

Reversed-phase high-performance liquid chromatography (RP-HPLC) is a cornerstone technique for peptide analysis due to its exceptional resolving power. In this webinar, we will explore how to optimize RP-HPLC parameters for effective separation of peptides derived from protein digests and analysis of PTMs analysis. Key topics include the role of stationary phase chemistry in influencing selectivity, and how column physical characteristics affect separation performance. We will also examine how mobile phase modifiers—such as trifluoroacetic acid (TFA), formic acid, and pH—impact chromatographic outcomes and compatibility with mass spectrometry (MS). Attendees will gain practical insights into method development strategies that enhance both resolution and detection sensitivity.<blockquote>Presenter: Mohit Patel (Application Engineer, Agilent Technologies, Inc.)Mohit Patel is part of the CSD Online AE Team. His primary focus is to support SMLC, Bio-Columns, and consumables.Before joining Agilent, Mohit was an Assistant Professor of Chemistry at Temple University. Mohit developed his passion for science through his experiences as a faculty researcher and a mentor. Mohit actively taught, developed curriculum, and served as senior personnel, with a leadership position, on funded grants, mentored research projects, and co-coordinator of STEAM related outreach services.Mohit has earned a Doctorate degree in Chemistry from Temple University in 2016.</blockquote>

Agilent Technologies: Advanced RP-HPLC Techniques for Peptide Analysis: From Column Chemistry to Mobile Phase Modifiers

Advanced RP-HPLC Techniques for Peptide Analysis: From Column Chemistry to Mobile Phase Modifiers

We will explore how to optimize RP-HPLC parameters for effective separation of peptides derived from protein digests and analysis of PTMs analysis.

Advanced RP-HPLC Techniques for Peptide Analysis

Discover how modern Listeria monitoring solutions can support faster, more reliable food and environmental testing, and help elevate your laboratory’s efficiency and confidence in results.Listeria remains one of the most challenging pathogens for the food industry due to its ability to persist in production environments and survive under conditions that inhibit many other bacteria, including refrigeration and high-salt processing. Its association with severe illness and food recalls places ongoing pressure on manufacturers and laboratories to detect contamination quickly and reliably across both food and environmental samples.This webinar will explore how Listeria monitoring solutions are evolving to meet these demands, particularly for laboratories balancing speed, cost and operational complexity. Traditional culture methods can delay critical decisions, while PCR and ELISA often require significant capital investment, infrastructure changes and specialist training, creating barriers for low to medium-throughput operations.Using Solus NanoFast™ Listeria as a practical example, the session will demonstrate how alternatives to culture, PCR, and ELISA can support next-day detection through simplified workflows that reduce training requirements and infrastructure changes. The discussion will also highlight how automated result interpretation and digital data management can improve consistency, traceability and audit readiness.<h4>During the session, you will learn how to:</h4><ul><li>Address common challenges in food and environmental Listeria monitoring</li><li>Evaluate cost-effective alternatives to culture, PCR, and ELISA for low to medium-throughput testing (up to ~50 samples/day)</li><li>Improve turnaround times without increasing workflow complexity</li><li>Support audit readiness through objective results and digital traceability</li><li>Align Listeria testing strategies with operational and regulatory requirements</li></ul>Whether you’re overseeing environmental monitoring or finished product testing, this session will deliver practical insights to optimise Listeria testing workflows for efficiency, consistency and confidence in results. Don’t miss this opportunity to streamline your approach to food and environmental Listeria monitoring.<blockquote>Presenter: Nathan Welch, Product Manager at PerkinElmer (Solus)Nathan Welch brings over 25 years of expertise in food safety and quality assurance to the stage. His career spans diverse roles that have shaped his deep understanding of the industry. Starting with two years in a food testing contract laboratory, Nathan advanced into nine years specializing in culture media testing at Oxoid/Thermo Fisher, where he honed his technical and analytical skills.He later transitioned into technical support at Thermo Fisher, providing critical guidance to clients and teams, before moving into product management, a role he has been in for the past 13 years, including nine years at Thermo Fisher and four years at Solus.Presenter: Jean-Paul Anthony, Application Scientist at PerkinElmer (Solus)J-P Anthony is the Applications Scientist for Solus/PerkinElmer contributing to training in the techniques and equipment for food pathogen testing. Prior to this he was a Senior Developmental Scientist and created many aspects of the enzyme and luminescent-based immunoassays including bacterial broth development from the time of the company’s inception in 2009. He trained in Immunology and Pharmacology at the University of Strathclyde before obtaining a PhD in novel drug discovery to combat protozoan parasitical infections at Queen Margaret University, Edinburgh.&nbsp;</blockquote>

New Food Magazine: Rethinking Listeria monitoring: faster, simpler solutions for food safety & environmental testing

Rethinking Listeria monitoring: faster, simpler solutions for food safety & environmental testing

How Listeria monitoring solutions are evolving to meet these demands, particularly for laboratories balancing speed, cost and operational complexity.

Listeria monitoring for food safety & environmental testing

<h4>Designing Robust Metabolomics Studies: From Biological Questions to Analytical Success</h4>Designing a robust metabolomics study requires balancing biological questions with analytical constraints. This webinar guides researchers through the critical decisions that shape successful outcomes - from sample collection and experimental design to choosing targeted or untargeted methods and the right analytical platforms.Attendees will learn practical strategies to minimize bias, enhance data quality, and align methodological choices with study goals. Ideal for scientists seeking clearer pathways through the complexity of metabolomics workflows.<h4>Who should attend?</h4>This webinar is tailored for professionals who want to strengthen their metabolomics study design, including:<ul><li>Academic researchers in biomedical sciences, exposomics, nutrition, and food research</li><li>Pharmaceutical scientists involved in early discovery and translational research</li><li>Anyone seeking practical strategies to reduce bias, improve data quality, and navigate complex metabolomics workflows</li></ul><h4>Key Learning Objectives</h4><ul><li>Understand the core components of metabolomics study design, including biological question definition, cohort selection, and strategies to reduce variability.</li><li>Learn how to choose between targeted, untargeted, and hybrid metabolomics approaches, and know when each method is most appropriate.</li><li>Identify best practices for sample collection, preparation, and QC workflows to ensure high-quality, reproducible data.</li><li>Recognize common pitfalls in metabolomics studies and apply practical strategies to improve robustness, interpretation, and downstream analysis.</li></ul>Ready to elevate your metabolomics research? Register now to secure your spot!<blockquote>Presenter: Dr. Elizabeth Want (Associate Professor in Clinical Mass Spectrometry, Imperial College London)Dr. Elizabeth Want is a Senior Lecturer in the Department of Metabolism, Digestion and Reproduction. She joined Imperial College in 2006 after working as a postdoctoral researcher at the Scripps Research Institute in La Jolla, CA. Prior to that, Elizabeth obtained her PhD in Clinical Biochemistry from King’s College London. At Imperial College, she became a Lecturer in 2007, Senior Lecturer in 2014 and Head of the Section of Bioanalytical Chemistry in 2022. She is also the Director of the Imperial International Phenome Training Centre which runs several hands-on courses in Metabolomics every year.Elizabeth has &gt;25 yrs of experience in mass spectrometry and chromatographic techniques and has spent the past 20 years working in the field of mass spectrometry-based metabolite profiling. Her research focuses primarily on the development and application of novel mass spectrometry (MS) assays for metabolic profiling and on the fusion of mass spectrometric methods with chemometric analysis.Her research at Imperial College has involved the development, optimisation and application of UPLC-MS methodologies for the analysis of biological samples. She applies these methods to biomedical research areas including cardiovascular disease, glioblastoma, neurodegenerative disorders and burn injury.Presenter:&nbsp;David Heywood (Senior Manager Biomedical Research Marketing, Waters Corporation)David has more than 28 years of experience in the mass spectrometry business and has performed many roles - both in the UK and the Americas,including technical hardware and software support, sales, marketing and business development.Now based at Waters’ Mass Spectrometry Head Quarters in Wilmslow UK,David has helped commercialize many of Waters successful high-resolution mass spectrometrybasedsolutions for discovery omics and is now responsible for global marketing strategies of these platforms.</blockquote>

Waters Corporation: Navigating Metabolomics Study Design and Method Choices

Navigating Metabolomics Study Design and Method Choices

Learn how to design robust metabolomics studies—from defining biological questions to selecting targeted or untargeted methods

<div>Discover new perspectives on the complexity of high‑grade serous ovarian cancer in our upcoming webinar, where cutting‑edge spatial multiomics meets real clinical impact. Learn how MALDI Imaging, combined with LMD‑based proteomics, spatial transcriptomics, and MALDI HiPLEX-IHC, is revealing previously unseen cellular subpopulations linked to treatment response and patient survival. This integrated strategy uncovers critical interactions between tumor and microenvironment that may drive chemoresistance and could pave the way for improved patient stratification and more personalized therapy. Join us to explore these groundbreaking results and see how spatial biology is transforming the future of cancer research.<h4>Key Learning Objectives</h4><ul><li>Learn how combining multimodal technologies can accelerate advanced biomarker discovery in oncology research</li><li>Understand how MALDI Imaging adds valuable, untargeted spatial context to existing transcriptomics, proteomics, or imaging workflows</li><li>Identify molecular subtypes and chemoresistance‑related interactions using spatial multiomics</li></ul><h4>Who Should Attend</h4><ul><li>Researchers in oncology, spatial biology, and multiomics</li><li>Clinical and translational scientists seeking new approaches for biomarker discovery and therapy prediction.</li><li>Pharma and biotech professionals developing targeted therapies or exploring tumor–microenvironment interactions.</li><li>Biologists working with transcriptomics, single‑cell, or microscopy methods who want to expand their capabilities into spatial and discover what MALDI Imaging can add</li><li>Anyone interested in cutting‑edge imaging mass spectrometry and its applications in cancer research</li></ul><blockquote>Presenter: Dr. Oliver Klein, Group Leader, Berlin Institute of Health at Charité, Berlin, GermanyDr. Oliver Klein received his master degree in Pharmaceutical/Chemical Engineering at the Beuth University of Applied Sciences and was subsequently focusing on the expression of protein domains to structure elucidation via NMR and mass spectrometry at the Leibniz Institute for Molecular Pharmacology (FMP) Berlin. Since 2007 he is working at the Charité, leading the Proteomics Unit at Berlin-Brandenburg Center for Regenerative Therapies (today BIH Center for Regenerative Therapies) since 2009. 2015 Dr. Klein earned his doctorate in the field of regenerative medicine, focusing on the detection of pathophysiological processes in tissue following cell therapy using Imaging MS and LC MS. From 2022 until today Dr. Oliver Klein leads the “Imaging mass spectrometry Unit at BIH” and is involved in several clinically driven projects including BMBFTR, DFG, EU and industry cooperations.</blockquote></div>

Bruker: Making the Invisible Visible: Unlocking the Potential of Imaging Mass Spectrometry in Ovarian Carcinoma and Beyond

Making the Invisible Visible: Unlocking the Potential of Imaging Mass Spectrometry in Ovarian Carcinoma and Beyond

Spatial multiomics in ovarian cancer showing how MALDI Imaging uncovers tumor heterogeneity, chemoresistance mechanisms, and clinically relevant biomarkers.

Imaging Mass Spectrometry in Ovarian Carcinoma

The microbiology laboratory plays a vital role in selecting antimicrobial susceptibility testing (AST) methods to guide treatment of severe infections in critically ill patients. Delayed or inaccurate results, especially in multi-drug-resistant cases, can lead to poor outcomes and higher mortality.In this SelectScience webinar Dr. James A. McKinnell, M.D. an infectious disease specialist, will describe how accurate minimum inhibitory concentration (MIC) data can improve turnaround times, optimize therapeutic decisions, and support the use of new treatments. The session will explore how reliable broth microdilution-based MICs for novel antibiotics enhance patient outcomes while reducing length of stay, adverse effects, and costs.Join the webinar to learn how antimicrobial stewardship efforts are most effective when supported by timely diagnostics and collaboration among microbiologists, clinicians, stewardship teams, and policymakers, helping to address the global challenge of antibiotic resistance in the post-Covid era.<h4>Key learning objectives:</h4><ul><li>Describe the role of the microbiology laboratory in guiding AST for critically ill patients.</li><li>Recognize the value of accurate MIC data in improving turnaround times, optimizing therapy, and supporting new antibiotic use.</li><li>Identify how antimicrobial stewardship programs rely on timely diagnostic data and collaboration to improve patient outcomes.</li><li>Discuss the importance of multidisciplinary collaboration among microbiologists, clinicians, stewardship teams, and policymakers to combat antibiotic resistance in a post-Covid world.</li></ul><h4>Who should attend?</h4><ul><li>Clinical microbiologists, laboratory technicians, lab managers, lab directors, infectious disease specialists, and infectious disease clinicians.</li></ul><h4>Accreditation statement</h4>SelectScience® is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. Attendees of these webinars may be entitled to 1.0 ACCENT Continuing Education Credits from the ADLM. This activity was planned in accordance with ACCENT® Standards and Policies. Verification of Participation certificates are provided to registered participants based on completion of the activity, in its entirety, and the activity evaluation. For questions regarding continuing education, please email education@myadlm.org.<blockquote>Presenter: Dr. James A. McKinnell (M.D. and Infectious Disease Specialist, Milefchik-Rand Medical Group, Torrance and Memorial Medical Center, Torrance CA)Dr. James A. McKinnell is an infectious disease specialist whose research focuses on healthcare-associated infections, particularly VRE, MRSA, and carbapenem-resistant organisms. He has authored over 40 publications on antibiotic optimization and antimicrobial resistance. Dr. McKinnell works closely with skilled nursing facilities in Los Angeles and Orange County (USA) to develop practical infection prevention and stewardship strategies. He also contributes as an invited speaker for the Infectious Disease Association of California and as a committee member for Los Angeles County’s HAI and antimicrobial resistance initiatives.Moderator: Sarah Thomas (Associate Editor, SelectScience)</blockquote>

SelectScience: Critical antimicrobial susceptibility testing results for critical patients: A 2025 perspective

Critical antimicrobial susceptibility testing results for critical patients: A 2025 perspective

Antimicrobial susceptibility testing highlighting role of accurate MIC data in optimizing therapy, stewardship, patient outcomes in critical infections.

Antimicrobial susceptibility testing results

<div>As biopharmaceutical manufacturers move toward continuous bioprocessing, downstream purification must evolve to keep pace with demands for efficiency, flexibility, and scalability. Multi-column chromatography is central to this shift, yet implementation challenges around consistency, changeover, and operational readiness remain.This webinar examines how advances in column design are helping teams overcome these barriers and accelerate adoption of continuous and semi-continuous purification strategies.Through real-world examples, attendees will gain insight into practical approaches that support robust processes, streamlined facilities, and faster deployment while advancing industry efforts to expand patient access to critical therapies.<h4>Attend this webinar to:</h4><ul><li>Understand the industry drivers accelerating the transition from batch to continuous bioprocessing</li><li>Explore the role of multi-column chromatography in integrated continuous manufacturing</li><li>Learn how pre-packed chromatography columns enable consistency, flexibility, and rapid implementation</li><li>Identify practical considerations for adopting pre-packed columns in continuous downstream operations</li></ul><blockquote>Presenter: Adam Nelson (Senior Product Manager at Repligen Corporation)Adam Nelson has 16 years of experience in pre-packed chromatography column manufacturing and product development. In his current role, as product manager for OPUS, large scale pre-packed chromatography columns, he is responsible for new product development, product line extensions and product innovation. In prior roles, Adam developed packing protocols that enable OPUS pre-packed chromatography column packing technology. Additionally, Adam led the team responsible for materials management, process control, and process development for OPUS large scale chromatography column manufacturing. He has a passion for customer service and leveraging his technical expertise to deliver an optimal customer experience. Adam holds a bachelor's in chemical engineering from the University of Massachusetts Amherst and a graduate's certificate in innovation management from Northeastern University.</blockquote></div>

Technology Networks: Enabling Continuous Bioprocessing With Multi-Column Chromatography

Enabling Continuous Bioprocessing With Multi-Column Chromatography

Webinar on multi-column chromatography and pre-packed columns for efficient, scalable continuous bioprocessing.

Continuous Bioprocessing With Multi-Column Chromatography

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><h4>Optimizing ion analysis: Ion chromatography with mass spectrometry</h4>Ion Chromatography–Mass Spectrometry (IC-MS) offers powerful analytical capabilities, but optimal sensitivity and long-term performance require thoughtful system setup. This webinar covers practical strategies for optimizing IC-MS, focusing on the components and decisions that most strongly impact routine analysis.<h5>Topics that will be covered include:</h5><ul><li>The importance of high-quality eluent</li><li>How the suppressor can affect instrument lifetime</li><li>How to select the right mass spectrometer for your sensitivity needs</li><li>Eluent management strategies to minimize stress on the MS, avoid contamination, and maintain stable performance</li></ul>Designed for both new and experienced users, this webinar delivers actionable tips to improve data quality, instrument reliability, and overall workflow efficiency.<blockquote>Presenter: Wai-Chi Man (Product Marketing Manager, Thermo Fisher Scientific)Wai-Chi has been with Thermo Fisher Scientific for more than eight years working with a wide range of customers in various industries. She provides ion chromatography (IC) support in method development, troubleshooting, sample preparation, training, seminars, events, and workshops. During this time, she has gained deep knowledge, skill, and understanding in areas such as IC-MS, IC-ICP-MS, carbohydrate analysis, metabolomics, and polar pesticides. Prior to joining the company, she worked for Wellcome Research and GlaxoSmithKline. Wai is passionate about promoting STEM to future scientists by encouraging, nurturing, and supporting them.Moderator: David Moore (Senior Product Manager, Ion Chromatography and Sample Preparation, Thermo Fisher Scientific)David Moore is a Senior Product Manager at Thermo Fisher Scientific, responsible for the company’s high-end ion chromatography systems portfolio. With more than 20 years of experience in scientific instrumentation, he focuses on translating complex customer needs into practical, high-performance solutions for advanced analytical laboratories worldwide.He holds an MChem in Medicinal Chemistry and works closely with global customers, applications teams, and R&amp;D to shape solutions for demanding workflows, including IC-MS and other hyphenated techniques.</blockquote></div></div></div>

Thermo Fisher Scientific: Optimizing ion analysis: Ion chromatography with mass spectrometry

Optimizing ion analysis: Ion chromatography with mass spectrometry

Webinar on optimizing IC-MS workflows: learn how eluent quality, suppressors, and MS selection impact sensitivity, stability, and long-term performance.

Ion chromatography with mass spectrometry

<div>The majority of human proteins are decorated with complex polysaccharides, called glycans, that play key roles in protein biology. Seemingly subtle changes in the structural configuration of glycans can severely impact protein functionality and biological processes. The non-template driven enzymatic glycan synthesis pathway is capable of producing a myriad of unique glycans. Already in healthy individuals, the diversity and stoichiometry of glycans on proteins can vastly differ in a tissue-, protein-, and site-specific manner. Protein glycosylation is also very dynamic since many different factors can influence glycan synthesis steps, as is painfully demonstrated in congenital disorders of glycosylation. For both genetic and acquired human disease, glycobiology offers unique clinical utility for biomarker applications, drug target discovery, and design of rational treatment strategies.The key to unlock the true potential of glycobiology for healthcare innovations lies within analytical capabilities to decipher the sugar code on glycoproteins. At present, analysis of glycopeptides from enzymatic protein digests is increasingly used to define glycan repertoire changes on proteins at glycosylation site resolution between conditions. It enabled biomarker discovery, diagnostic applications, and novel insights in protein glycobiology. Nevertheless, glycopeptide profiling is typically unable to resolve the fine structural or even topological features of glycan-moieties. This limitation makes the interpretation of results challenging and may lead to incorrect conclusions since glycan trees are typically inferred from just sugar compositions. It is therefore paramount to move towards structural glycoproteomics by resolving this bottleneck through combined hardware, software, and method development.<h4>Key Learning Objectives</h4><ul><li>Updated glycoproteomics workflows</li><li>Glycoproteomics for translational research</li><li>From glycopeptide profiling to structural insights</li><li>How real-tims bioinformatics can be used there</li><li>timsOmni™, Glyco-PASEF® &amp; Myriad</li></ul><h4>Who Should Attend</h4><ul><li>Translational biology researchers</li><li>Proteomics researchers and core facility managers</li><li>Structural (glyco) protein researchers</li><li>Proteomics bioinformaticians</li><li>Biomarker discovery researchers</li></ul><blockquote>Presenter: Hans Wessels, Ph.D., Glycoproteomics Scientist, Radboudumc, Nijmegen, NetherlandsDr. Hans Wessels has been working in the field of MS-based proteomics since more than 20 years now. He got his Ph.D. in mitochondrial proteomics from Radboud University Nijmegen and has developed deep expertise in analytical biochemistry, glycobiology, and translational research.He is now is a Proteomics Scientist and Director of the Radboud Technology Center for Mass Spectrometry at the Radboud University Medical Center (RUMC) in Nijmegen, The Netherlands. His work is embedded within the Translational Metabolic Laboratory, Department of Human Genetics, where he focuses on disease-specific proteoforms, glycoproteomics, and advanced mass spectrometry workflows.He has developed deep expertise in analytical biochemistry, glycobiology, and translational research. His research combines cutting-edge PASEF-based mass spectrometry, real-time search strategies, and bioinformatics to advance biomarker discovery and clinical applications.Dr. Wessels is an active contributor to collaborative initiatives including the Radboud Consortium for Glycoscience, the X-omics Initiative, and the EnFORCE project, and frequently engages in scientific dissemination through webinars and international collaborations.</blockquote></div>

Bruker: Towards structural glycoproteomics

Towards structural glycoproteomics

Webinar on advanced glycoproteomics workflows using PASEF-based MS and bioinformatics to reveal structural glycan features for biomarker discovery.

Join us for a live webinar on next-generation authentication of spices, honey, and meat using the SCIEX QTRAP and HRMS platforms. Food adulteration and mislabeling pose serious challenges to quality, safety, and regulatory compliance. In this session, our experts will demonstrate how advanced mass spectrometry solutions from SCIEX enable accurate, sensitive, and reliable authentication of complex food matrices. This webinar is ideal for professionals involved in food testing, quality control, regulatory compliance, and analytical research. Register now to gain practical insights into next-generation food authentication workflows.<h4>Key highlights:</h4><ul><li>Determination of aconitum alkaloids in adulterated spice powders using QTRAP system.</li><li>Honey authenticity using SCIEX QTRAP and HRMS platform.</li><li>Multiple meat speciation and authentication on the QTRAP System.</li></ul><blockquote>Speaker: Kankan Jana, Application Support Specialist</blockquote>

SCIEX: Next-generation authentication of spices, honey, and meat using SCIEX QTRAP and HRMS system

Next-generation authentication of spices, honey, and meat using SCIEX QTRAP and HRMS system

Join us for a live webinar on next-generation authentication of spices, honey, and meat using the SCIEX QTRAP and HRMS platforms. 

Authentication of spices, honey, meat by SCIEX QTRAP

The growing prevalence of fentanyl analogues and nitazene derivatives presents a significant challenge for forensic and toxicology laboratories. With over 250 analogues to optimize—each associated with low sample volumes, high toxicity, and high cost—traditional workflows can be time-consuming and resource-intensive.&nbsp;In this webinar, we will demonstrate how the Xevo TQ-S micro combined with QuanOptimize streamlines method development, offering practical tips and tricks for efficient optimization. We’ll also explore how PIC Scan enhances confidence in compound identification, with additional best practices to maximize reliability. Finally, discover how this approach delivers a ready-to-implement package featuring pre-configured methods and comprehensive reference data for 250 fentanyl analogues and nitazene derivatives—empowering laboratories to accelerate analysis and improve safety.<blockquote>Presenter: Marco Rentsch (Principal Clinical Support Specialist, Waters Corporation)Marco brings nearly two decades of expertise in chromatography and mass spectrometry. Since joining Waters in 2012, he has held roles focused on application support and scientific enablement. Since 2022, Marco has been a Principal Clinical Support Specialist in the European Clinical Support Team. In this capacity, Marco designs and delivers clinical solutions providing tailored training and ensures ongoing support to help customers achieve success.</blockquote>

Waters Corporation: Development of a Targeted Multiple Reaction Monitoring (MRM) Method for Fentalogues and Nitazene Derivatives

Development of a Targeted Multiple Reaction Monitoring (MRM) Method for Fentalogues and Nitazene Derivatives

We will demonstrate how Xevo TQ-S micro combined with QuanOptimize streamlines method development, offering practical tips and tricks for optimization.

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