<p><strong>Wastewater treatment plants struggle every day with substances that don’t simply disappear from the water. The removal of nitrogen compounds is very important at these plants. If too much of these substances remains in the water, they harm rivers and the life within them. </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5403"><strong>Karel Havlíček </strong></a><strong>from CXI TUL was a co-investigator on the HYMNA project, which combined two well-known treatment technologies into a single system. And he added something to them that isn’t commonly used at treatment plants: nanofibers.</strong></p><p>The full name of the project is <strong>“Hybrid MBR-MBBR System Using Nanomaterials for Advanced Wastewater Treatment.” </strong>The acronym is <strong>HYMNA</strong>. “<i>It sounds a bit grand</i>,” laughs co-investigator <strong>Karel Havlíček from the Department of Environmental Protection Technology</strong>. But the goal was indeed grand. The water that flows out of a treatment plant isn’t always as clean as it could be. And that’s a problem worth solving.</p><h4><strong>A Screen and Beads</strong></h4><p>Behind the acronyms <strong>MBR and MBBR</strong> lie two technologies that treatment plants typically deploy separately. But Karel combined them into a single process and demonstrated that together they can work significantly better. He validated the combination in practice and used it to design a technology with a clear procedure, measurable results, and the potential for real-world application.</p><p>The <strong>MBR </strong>functions as a fine screen. The membranes trap impurities, organic matter, and undissolved particles. But even then, the process isn’t complete—nitrogenous compounds still remain in the clarified water.</p><p>To address this, Karel Havlíček and his partners implemented the second part of the technology: <strong>MBBR</strong>. Small plastic beads with holes and nanofibers inside move freely in the tank with the help of aeration. Microorganisms grow and live on the surface of the nanofibers, converting ammonia nitrogen into nitrates.</p><p><strong>Why does this matter? </strong>Ammoniacal nitrogen is toxic to fish; it damages their gills and, at higher concentrations, kills them. An excess of nitrogen triggers algae blooms, causing the water to turn green, depleting oxygen levels, and suffocating aquatic life.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg 117w," sizes="100vw" width="768" height="1024"></p><h4><strong>Beads with a Nanofiber Core</strong></h4><p>The beads are no accident. Karel inserted nanofiber carriers—a fine fibrous material to which microorganisms quickly and firmly attach—into plastic bodies with holes. He had already proposed this concept in his dissertation.</p><p>The path to the final design was not straightforward. Originally, it was a nanofiber layer. However, it gradually washed off the beads. They replaced it with yarn, which holds its shape. The result is a utility model for new biomass carriers.</p><p>The main advantage is the speed of colonization. On conventional materials, colonization takes much longer. Microorganisms colonize the nanofibers quickly. This is crucial, especially where the water is hostile or toxic to them.</p><p>Industrial wastewater is often so polluted that bacteria cannot survive on conventional carriers. On a nanofiber surface, however, they manage to attach themselves before the environment destroys them. The system then works even where other technologies would fail.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg 117w," sizes="100vw" width="768" height="1024"></p><h4><strong>A Surprising Number</strong></h4><p>The most important factor was how the system would handle ammonia nitrogen. The team even tested extreme concentrations of <strong>up to eighty milligrams per liter</strong>. And that’s not just fine-tuning. That’s a stress test pushing the limits—one that could cripple or completely halt the activity of the purifying microorganisms.</p><p><strong>The system handled it</strong>. At the outflow, they measured<strong> less than one milligram per liter</strong>.</p><p>“<i>We achieved a level that even a conventional treatment plant often can’t handle</i>,” Karel said, expressing his surprise.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg 117w," sizes="100vw" width="768" height="1024"></p><h4><strong>Container-Based Treatment Plant</strong></h4><p>Combining the two technologies brought an added benefit. The system can function not only as a post-treatment unit following a standard treatment plant but also as a standalone modular treatment plant. No construction is needed; the system can be delivered, connected, and put into operation.</p><p>“<i>Industrial facilities will especially appreciate this. Companies that currently transport contaminated water in barrels as hazardous waste could handle part of the treatment themselves</i>,” explains Karel. According to him, this would mean less waste, less logistics, and lower costs for companies.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg 117w," sizes="100vw" width="768" height="1024"></p><h4><strong>A Myth That Didn’t Pan Out</strong></h4><p>Apart from the main project, Karel’s team asked themselves another question: Can microorganisms in a standard wastewater treatment plant biofilm on carriers break down micropollutants—that is, traces of medications or pesticides that end up in the water?</p><p>Some studies suggested that this might be possible.</p><p>But the enthusiasm quickly faded. <i>“No degradation occurs. The micropollutants simply accumulate in the system</i>,” Karel states. The system captures them but does not destroy them. That requires more powerful methods, such as ozone or UV radiation.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg 110w," sizes="100vw" width="724" height="1024"></p><blockquote><p>The HYMNA project, part of the TREND program of the Technology Agency of the Czech Republic, in collaboration with ENVI-PUR, s.r.o. (principal investigator) and Pražské vodovody a kanalizace, a.s.</p></blockquote>

Beads with a nanofiber core. This is a better way to purify water.

<p><strong>In the weeks of August 3 and 10, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Agilent Technologies: Characterising Advanced Materials with the Agilent UV-Vis-NIR: From Thin Films and Solar Cells to Glass and Optical Coatings</strong></h5><ul><li>Th, 6.8.2026 07:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6396">Registration</a></li></ul><p>Discover how Agilent UV-Vis-NIR spectrophotometers support the characterization of thin films, solar cells, glass, optical coatings, and other advanced materials.</p><h5><strong>2. Waters Corporation: LC Coffee Breaks: Mastering Overpressure - Prevention and Solutions that Work</strong></h5><ul><li>Th, 6.8.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6410">Registration</a></li></ul><p>Take a practical LC coffee break and learn how to identify the causes of excessive system pressure, prevent overpressure, and resolve common problems efficiently.</p><h5><strong>3. US HUPO: Spatial Imaging Series: More Than Mass Spec</strong></h5><ul><li>Tu, 11.8.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6362">Registration</a></li></ul><p>Explore advances in mass spectrometry imaging and discover innovative spatial analysis approaches that extend beyond conventional MS techniques.</p><h5><strong>4. SCIEX: PFAS Asia Summit 2026</strong></h5><ul><li>We, 12.8.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6355">Registration</a></li></ul><p>Explore evolving PFAS regulations, major industry trends, and LC-MS/MS sample preparation workflows for robust and reliable PFAS detection.</p><h5><strong>5. Technology Networks: Unlocking New Insights Into PFAS Distribution and Biological Impact</strong></h5><ul><li>We, 12.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6397">Registration</a></li></ul><p>Learn how MALDI-TIMS-MS maps PFAS distribution in tissues, differentiates isomers, and reveals associated changes in the hepatic lipidome.</p><h5><strong>6. Agilent Technologies: Why Your Column Isn’t Always the Culprit: Smarter HPLC Troubleshooting</strong></h5><ul><li>We, 12.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6349">Registration</a></li></ul><p>Learn practical diagnostic steps to identify the true causes of retention shifts, pressure spikes, and poor peak shapes without automatically blaming the LC column.</p>

Webinars LabRulezLCMS Weeks 32-33/2026

New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products

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The Institute for Nanomaterials, Advanced Technologies and Innovations of the Technical University of Liberec, also known as CXI TUL, was founded in 2009. Our mission is to support TUL's long-term vision of collaboration with industry and innovation.

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<p><strong>Unexpected changes to our chromatography often lead us to suspect the column first. &nbsp; But, in many cases, the true source of the problem is somewhere else in the system. &nbsp;In this webinar, we’ll explore some of the common chromatography issues we most often hear about as technical support specialists. Whether you’re dealing with shifts in retention time, pressure fluctuations, unexpected peaks, ghost peaks, missing peaks, or your peak shapes just don’t look right, we’ll walk through practical steps for diagnosing and resolving the problem. Having an understanding for where issues typically occur can help us to quickly identify the problem, implement the right corrective action, and prevent the problem from recurring in the future.</strong></p><blockquote><p><strong>Speaker:</strong> Jean Lane (Application Engineer, Agilent Technologies, Inc.)</p><p>Jean has been employed with Agilent since Nov 2010 in technical and applications support and has a primary role supporting Agilent’s full line of LC columns and consumables, which also includes support for Agilent’s GPC/SEC product line. She came to Agilent thru acquisition of Varian and the former Polymer Laboratories. Jean has 20 plus years of technical and applications support for both HPLC and GPC consumable products. In addition to practical chromatography experience in the laboratory, she has had many, many years in her technical role involving customer support providing assistance and troubleshooting for customer chromatography issues.</p></blockquote>

Agilent Technologies: Becoming A Better Chromatographer Webinar Series

Why Your Column Isn’t Always the Culprit: Smarter HPLC Troubleshooting

Master HPLC troubleshooting with Agilent. Learn to diagnose retention shifts, pressure issues, and ghost peaks outside of the column environment

Smarter HPLC Troubleshooting: Beyond the Column Issues

<h4><strong>What’s trending across Asia and what you should know next</strong></h4><p><strong>PFAS Asia Summit is back in 2026! Join us with leading experts across science and industry to explore the latest PFAS developments shaping Asia. From evolving regulatory frameworks to cutting-edge research and analytical innovation, this summit offers a focused platform to understand emerging risks, industry responses - helping you stay informed and prepared in a rapidly changing PFAS landscape.</strong></p><h4><strong>What you will learn:</strong></h4><ul><li>Latest PFAS regulatory updates across global and Asian markets</li><li>Emerging PFAS trends in key industries, including agriculture, electronics, and pharmaceuticals</li><li>Advances in sample preparation and integrated LC-MS/MS technologies for PFAS detection and analysis</li></ul><h4><strong>Agenda</strong></h4><h5><strong>09:00 - 09:05 a.m. Welcome &amp; Introduction</strong></h5><h5><strong>09:05 - 09:35 a.m. PFAS around the world - Regulatory and analytical trends</strong></h5><ul><li>Holly Lee (SCIEX)</li></ul><h5><strong>09:35 - 10:05 a.m. Utilizing LC-MS for proactive PFAS detection in Pharma</strong></h5><ul><li>Eshani Galermo (SCIEX)</li></ul><h5><strong>10:05 - 10:35 a.m. Advanced strategies in LC-MS/MS for clean-up and analysis of PFAS compounds in various sample matrices</strong></h5><ul><li>Namrata Saxena (Phenomenex)</li></ul><h5><strong>10:35 - 11:00 a.m. Behavior and metabolic effects of PFAS in wheat</strong></h5><ul><li>Yanwei Zhang (China)<ul><li><i>*Speaking language: Chinese</i></li></ul></li></ul><h5><strong>11:00 - 11:25 a.m. Standardization of IEC test methods for PFAS regulation compliance in the electrical, electronics, and automotive plastic industries</strong></h5><ul><li>Jaehak Jung (Korea)<ul><li><i>*Speaking language: Korean</i></li></ul></li></ul><h5><strong>11:25 - 11:55 a.m. Nontarget screening of PFAS transformation products during photoelectrochemical degradation of PFAS in water</strong></h5><ul><li>Jheng-Sian, Yang (Taiwan)<ul><li><i>*Speaking language: Chinese</i></li></ul></li></ul><h5><strong>11:55 a.m. - 12:10 p.m. Q&amp;A</strong></h5><p><i>*Sessions delivered in non-English languages will be supported with English subtitles.</i></p><blockquote><p><strong>Speaker: </strong>Yanwei Zhang, Ph.D. (Associate Researcher, Agro-Environmental Protection Institute, Ministry of Agriculture and Rural Affairs, China)</p><p><strong>Speaker:</strong>&nbsp;Jaehak Jung, Ph.D. (Chief Technology Officer (CTO), Korea Institute of Analytical Science and Technology (KAIST), Republic of Korea)</p><p><strong>Speaker:</strong> Jheng-Sian Yang, Ph.D. (Assistant Professor, Department of Safety, Health and Environmental Engineering, National United University, Taiwan)</p><p><strong>Speaker:</strong> Holly Lee (Staff Scientist, Global Technical Marketing, Food, SCIEX)</p><p><strong>Speaker:</strong> Eshani Galermo (Staff Scientist, Pharma/Biopharma Quant Lead, SCIEX)</p><p><strong>Speaker:</strong> Namrata Saxena (Technical Manager, Asia/Pacific, Phenomenex)</p><p><strong>Speaker:</strong> See Chung Yip (Field Application Manager, SCIEX)</p></blockquote>

PFAS Asia Summit 2026

Stay ahead of the changing PFAS landscape in Asia. Learn about evolving regulations, industry impacts, and cutting-edge LC-MS/MS analytical methods

PFAS Asia Summit 2026: Trends, Regulations & LC-MS/MS  

<div><h4><strong>Minimizing QC Release Risk Through Molecule‑Specific Analytics in Empower™ CDS</strong></h4><p><strong>As MALS gains adoption in QC, many biopharmaceutical labs face a disconnect between absolute molecular measurements and confident lot‑release decisions. Reliance on relative SEC methods, manual calculations, and subjective interpretation can obscure risks related to aggregation, recovery, and molecular distribution - often emerging only during method transfer or regulatory review.</strong></p><p>In this webinar, we show how integrating QC‑ready MALS into an Empower™ workflow enables labs to quantify and manage release risk. Standardized calculations convert raw MALS data into objective, reviewable metrics - reducing analyst‑dependent interpretation and supporting defensible release decisions before risks become compliance issues.</p><h4><strong>What will you learn?</strong></h4><ul><li>Transition MALS from characterization to routine QC testing</li><li>Automate critical molecular metrics tied to release specifications</li><li>Improve consistency, traceability, and confidence in release decisions</li></ul><h4><strong>Who should attend</strong></h4><ul><li>QC Managers and Directors responsible for release testing</li><li>MSAT and Method Transfer teams moving methods into QC</li><li>Analytical Development scientists supporting late stage programs</li><li>Regulatory Affairs and Compliance professionals focused on audit readiness</li><li>Organizations working with proteins, peptides, biologics, or complex modalities where aggregation and heterogeneity impact release decisions</li></ul><blockquote><p><strong>Presenter:</strong> Colette Quinn, Ph.D. (Light Scattering Portfolio Owner, Waters Corporation)</p><p>Colette Quinn is a Sr. business development manager in the biopharmaceutical group at Waters Corporation. Her focus is around biophysical solutions and how to integrate biophysical and biochemical approaches to enable a “totality of evidence” based approach to problems.</p></blockquote><blockquote><p><strong>Presenter:</strong> Neil Lander (Senior Principal Product Manager, Waters Corporation)</p><p>Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Senior Principal Product Manager focusing on Informatics solutions.</p><p>He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives.</p></blockquote></div>

Waters Corporation: Reduce QC Release Risk with Molecule Specific Analytics: QC Ready MALS in Empower™ CDS

Reduce QC Release Risk with Molecule Specific Analytics: QC Ready MALS in Empower™ CDS

Reduce biopharma release risks by integrating MALS into Empower CDS. Automate molecular metrics, eliminate manual math, and secure audit readiness

Reduce QC Release Risk with Empower Integrated MALS

<p><strong>Discover how mass spectrometry imaging is expanding beyond molecular detection in this US HUPO webinar featuring experts discussing innovative imaging approaches and emerging biomedical applications.</strong></p><blockquote><p><strong>Presenter: </strong>Dr. Angela Kruse (Assistant Professor, The Ohio State University)</p><p><strong>Presenter: </strong>Dr. Yasmin Shanneik (Postdoctoral Associate Baylor College of Medicine)</p><p><strong>Moderator: </strong>Dr. Jessica Moore</p><p><strong>Moderator: </strong>Dr. Colleen Crouch</p></blockquote>

US HUPO: Spatial Imaging Series: More Than Mass Spec

Spatial Imaging Series: More Than Mass Spec

Join the US HUPO webinar to explore advances in mass spectrometry imaging and innovative approaches beyond conventional MS analysis.

<p><strong>As materials become increasingly sophisticated, understanding their optical properties is essential for driving innovation, improving product performance, and ensuring quality. Whether developing anti-reflective coatings, optimising solar cell efficiency, designing specialty glass, or researching next-generation materials, accurate optical characterisation is a critical part of the workflow.</strong></p><p>Join us for this webinar to discover how the Agilent UV-Vis-NIR spectrophotometer enables researchers and industry professionals to measure and characterise a broad range of optical properties across diverse sample types and applications.</p><p>The webinar will showcase measurement techniques for transmission, reflectance, diffuse reflectance, and angular measurements, highlighting how the Agilent UV-Vis-NIR platform delivers reliable and reproducible data for both research and industrial applications.</p><h4><strong>Why Attend?</strong></h4><p><strong>In this session, you will learn:</strong></p><ul><li>How the Agilent UV-Vis-NIR can be used to characterise thin films, coatings, solar materials, and glass.</li><li>Techniques for measuring transmission, reflectance, and diffuse reflectance with confidence.</li><li>Methods for determining film thickness and evaluating optical performance.</li><li>How specialised accessories expand measurement capabilities for challenging samples.</li><li>Best practices for obtaining accurate, reproducible results across a variety of applications.</li><li>Real-world examples demonstrating how optical measurements can accelerate research and product development.</li></ul><h4><strong>Who Should Attend?</strong></h4><p><strong>This webinar is designed for:</strong></p><ul><li><strong>Academic Researchers and Students</strong><ul><li>Researchers in materials science, physics, chemistry, and engineering.</li><li>Scientists investigating thin films, nanomaterials, optical materials, and photonic devices.</li><li>Graduate students and postdoctoral researchers seeking advanced optical characterisation techniques.</li></ul></li><li><strong>Solar and Photovoltaics</strong><ul><li>Scientists and engineers developing solar cells and photovoltaic materials.</li><li>Researchers evaluating anti-reflective coatings and light management strategies.</li><li>Teams working to improve solar cell efficiency through optical optimisation.</li></ul></li><li><strong>Glass and Coatings Industries</strong><ul><li>Manufacturers of architectural, automotive, and specialty glass.</li><li>Researchers developing low-emissivity and anti-reflective coatings.</li><li>Quality control and R&amp;D professionals responsible for optical performance testing.</li></ul></li><li><strong>Advanced Materials and Industrial R&amp;D</strong><ul><li>Thin film and semiconductor researchers.</li><li>Optical coating manufacturers.</li><li>Scientists working with displays, sensors, filters, and advanced functional materials.</li><li>Analytical laboratories requiring precise optical characterisation.</li></ul></li></ul><h5><strong>Featured Applications</strong></h5><ul><li>Thin film and multilayer coating analysis</li><li>Anti-reflective and optical coating characterisation</li><li>Solar cell and photovoltaic material evaluation</li><li>Optical filter transmission and blocking measurements</li><li>Architectural and specialty glass analysis</li><li>Reflectance measurements at varying angles of incidence</li><li>Film thickness determination</li><li>Diffuse reflectance measurements of scattering materials</li><li>Optical characterisation of emerging materials in academia and industry</li></ul><p>Discover how the Agilent UV-Vis-NIR platform combines exceptional optical performance, flexible sampling accessories, and intuitive workflows to provide the insights needed to advance research, optimise products, and solve challenging analytical problems.</p><blockquote><p><strong>Presenter: </strong>Mr. Rajwar Chandra (Product Specialist - Spectroscopy, Agilent Technologies)</p><p>Chandra Rajwar is a Product &amp; Market Specialist with over 20 years of experience in Molecular Spectroscopy products and analytical instrumentation. He specializes in UV-Vis, FTIR, Raman, and related spectroscopy solutions, supporting customers with application development, workflow optimization, and analytical excellence across pharmaceutical, chemical, environmental, and research industries.</p></blockquote><blockquote><p><strong>Presenter: </strong>Ms. Vijaya Jyothi (Product Specialist - Spectroscopy, Agilent Technologies India Pvt. Ltd.)</p><p>Vijaya Jyothi is a seasoned product specialist at Agilent Technologies. She manages the spectroscopy division, having extensive expertise in spectroscopy applications across diverse industries, offering deep insights and solutions tailored to varied analytical needs.</p></blockquote>

Agilent Technologies: Characterising Advanced Materials with the Agilent UV-Vis-NIR - From Thin Films and Solar Cells to Glass and Optical Coatings

Characterising Advanced Materials with the Agilent UV-Vis-NIR: From Thin Films and Solar Cells to Glass and Optical Coatings

Characterize thin films, solar cells, and coatings with Agilent UV-Vis-NIR. Master reflectance, transmission, and angular measurement workflows

Materials Characterization with Agilent UV-Vis-NIR

<div><p><strong>Per- and polyfluoroalkyl substances (PFAS) are a diverse class of persistent environmental contaminants that can accumulate in biological systems and pose potential risks to human and environmental health. Understanding how different PFAS structures behave within living organisms, including the distribution of individual isomers and their biological effects, remains a significant analytical challenge.</strong></p><p>In this webinar, researchers will demonstrate how matrix-assisted laser desorption/ionization trapped ion mobility spectrometry mass spectrometry was used to differentiate PFAS isomers, analyze PFAS-exposed bacterial biomass, and investigate tissue-specific PFAS distribution in a mouse model.</p><p>The session will also explore PFAS-associated changes to the hepatic lipidome, highlighting the potential of advanced mass spectrometry approaches for PFAS research.</p><h4><strong>Attend this webinar to:</strong></h4><ul><li>Understand advanced mass spectrometry approaches for PFAS detection, characterization, and isomer differentiation</li><li>Learn how spatial imaging techniques reveal the biological impact and tissue distribution of environmental contaminants</li><li>Explore emerging applications of spatial mass spectrometry for studying microplastics and other environmental pollutants</li></ul><blockquote><p><strong>Presenter:</strong> &nbsp;Elizabeth Neumann, PhD &nbsp;( Assistant Professor, University of California, Davis)</p><p>&nbsp;Elizabeth Neumann is an assistant professor in the chemistry department at UC Davis. Her research focuses on understanding the molecular and cellular architecture behind complex human disorders, such as renal cell carcinoma, spina bifida and Alzheimer's Disease.&nbsp;</p></blockquote><blockquote><p><strong>Presenter: </strong>Autumn Qiu, PhD ( Assistant Professor, Michigan State University)</p><p>&nbsp;Prof. Tian (Autumn) Qiu earned her Bachelor of Science in chemistry from Peking University and her PhD from the University of Minnesota. Autumn’s PhD studies focused on nanotoxicity mechanisms in environmental bacteria at the Center for Sustainable Nanotechnology. She was a Beckman Postdoctoral Fellow at the University of Illinois at Urbana-Champaign and worked on D-amino acids in the microbiome-gut-brain axis. She joined Michigan State University as an Assistant Professor in 2022. Her lab investigates interactions among environmental contaminants, microbial metabolism, and host responses using mass spectrometry, particularly MALDI-MS, integrated with animal models and toxicological analyses.&nbsp;</p></blockquote></div>

Bruker: Unlocking New Insights Into PFAS Distribution and Biological Impact

Unlocking New Insights Into PFAS Distribution and Biological Impact

Explore advanced PFAS analysis with MALDI-TIMS-MS imaging. Discover how to differentiate isomers and investigate tissue-specific lipidome changes

Spatial PFAS Analysis: MALDI-TIMS-MS

<h4><strong>By attending this presentation you will:</strong></h4><ul><li>Explore a range of chromatographic separation modes for Bicycle® molecules and their impurities.</li><li>Gain practical insights into the identification and characterization of impurities and degradation products.</li><li>Learn a systematic approach to developing effective separation methods.</li><li>Recognize best practices for optimizing separations to support analytical development and stability studies.</li></ul><h4><strong>Event Overview</strong></h4><p>Bicycle® molecules are novel medium molecules and provide a unique set of challenges to separate and identify impurities and degradants. They are fully synthetic, short peptides that loop together into two constrained rings. This unique bicyclic shape allows them to mimic the target-binding capabilities of large antibodies while retaining the rapid tissue penetration and manufacturing advantages of small molecules.</p><p>The presentation covers a broad approach to achieving separation with Bicycle® molecules and will touch on a large range of separation modes.</p><blockquote><p><strong>Speaker: </strong>Andrew Feilden (Senior Director, Analytical Sciences, Bicycle Therapeutics)</p><p>Dr Feilden joined Bicycle in October 2022 where he leads the CMC analytical science team. &nbsp;He has over 25 years' experience in the pharmaceutical industry having worked for both CROs and large pharma. &nbsp;His area of work has been around trace analysis and he is an expert in extractables and leachables. &nbsp;He completed his degree and DPhil at the University of York.</p></blockquote>

Agilent Technologies: Analysis of Bicycle® Molecules - Novel Medium Molecules

Analysis of Bicycle® Molecules: Novel Medium Molecules

Explore chromatographic separation modes for Bicycle® peptides. Learn systematic method development to analyze impurities and degradants

Analyzing Bicycle® Molecules: Separation & Impurities

<h4><strong>LC Coffee Breaks Free Webinar Series</strong></h4><p>Each episode focuses on answering a specific challenge faced by chromatographers, helping you improve efficiency, solve problems faster, and stay up to date with the latest trends in Liquid Chromatography.</p><h4><strong>Episode 1</strong></h4><h5><strong>Mastering Overpressure - Prevention and Solutions that Work</strong></h5><h4><strong>What will you learn</strong></h4><ul><li>Overpressure is a common LC challenge that can lead to downtime and unreliable results. Learn or review how to:</li><li>Identify key causes and solve them</li><li>Prevent issues in practical ways</li></ul><h4><strong>Why you should attend</strong></h4><p>Get practical, users insights you can immediately apply in your daily LC laboratory work.&nbsp;<br>In just a short coffee-break session, you'll gain valuable tips on troubleshooting, method development, method transfer, technology updates, column chemistries, and real-world applications.</p><blockquote><p><strong>Speaker: </strong>Walter Migliaccio (Sales Application Chemist, Waters)</p></blockquote>

LC Coffee Breaks: Mastering Overpressure - Prevention and Solutions that Work

Learn how to identify, solve, and prevent LC system overpressure. Join Waters' short webinar to eliminate downtime and keep your analysis running

Mastering Overpressure - Prevention and Solutions

<h4><strong>Key Learning Points</strong></h4><ul><li>Understand how to improve resolution with different stationary phases and mobile phase selectivity.&nbsp;</li><li>Learn key method development strategies for unknowns and complex mixtures.</li><li>Build LC methods that are reproducible, rugged, and transferable.</li><li>Review real examples of how to separate difficult compound classes.</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Any LC users who want practical strategies for method development and optimization, or scientists who struggle with method reproducibility, ruggedness, or robustness.</li></ul><h4><strong>One webinar, two viewing options</strong></h4><p>We know you're busy, select a viewing session that works best for you.</p><h5><strong>Viewing Options</strong></h5><p><strong>Session 1</strong></p><ul><li><strong>Tuesday, August 11, 2026</strong></li><li>Los Angeles: 10:00 AM PT | New York: 1:00 PM EST</li><li>Mexico City: 12:00 PM CDT</li></ul><p><strong>Session 2</strong></p><ul><li><strong>Wednesday, &nbsp;August 12, 2026</strong></li><li>London: 9:00 AM BST | Berlin: 10:00 AM CEST&nbsp;</li><li>Mumbai: 1:30 PM IST</li></ul><blockquote><p><strong>Speaker:</strong> Grace Guo (Senior Technical Specialist, Phenomenex)</p><p>&nbsp;Grace Guo graduated from Johns Hopkins University with a Master’s degree in Material Science and Engineering. She joined Phenomenex Technical Team in 2017 providing technical support globally. With more than 9 years of experience in SPE, HPLC and GC, she delivered 90+ seminars and webinars globally covering food and environmental, clinical, pharma and biopharma industry.&nbsp;</p></blockquote>

Phenomenex: Unknowns Uncovered - Smart LC Strategies That Work

Unknowns Uncovered: Smart LC Strategies That Work

Master smart LC method development for unknown compounds. Learn Phenomenex strategies for better resolution, stationary phase selectivity, and ruggedness

Smart LC Strategies That Work

<p><strong>Therapeutic peptides are a fast-growing pharmaceutical drug class, but they present unique analytical challenges due to closely related process impurities, degradation products, and higher-order aggregate species. This webinar shows how complementary chromatographic workflows can be used to address those challenges, with examples spanning assay, related substances, stability-indicating analysis, and aggregate assessment. Real-world applications will cover aggregation profiles of key GLP-1 receptor agonists, including semaglutide, liraglutide, and tirzepatide.</strong></p><h4><strong>Key Learning Points</strong></h4><ul><li>Understand the main analytical challenges involved in therapeutic peptide characterization, including closely related impurities, degradation products, and aggregate species.</li><li>Describe where reversed-phase chromatography and size exclusion chromatography fit across therapeutic peptide development workflows.&nbsp;</li><li>Learn how different reversed-phase selectivities were used for semaglutide assay, related substances, and stability/degradant studies, and understand how similar workflows can be adapted for other GLP-1 analogs, including tirzepatide.</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Any liquid chromatography users working with, or interested in analyzing peptide therapeutics by HPLC. &nbsp;</li></ul><blockquote><p><strong>Speaker:</strong> Sean Orlowicz (Principal Market Development Manager, Phenomenex)</p><p>Sean Orlowicz has been working in the field of analytical chemistry for over 23yrs. After receiving his degree in Chemistry from the University of Illinois at Chicago, he started his career in large scale synthesis, using HPLC and GC techniques in reaction monitoring and purification. Sean took this experience to Phenomenex in 2003, working on site with clients worldwide on method development, troubleshooting and method transfer. Sean explored instrumentation for a few years, growing to specialize in LCMS, before returning to Phenomenex to help build and manage Phenomenex’s new applications laboratory. Since then, Sean has been driving innovation and growth though Business Development efforts, and most recently, in 2025 Sean has taken a Market Development Management role, spearheading our global efforts in Pharmaceuticals.&nbsp;</p></blockquote>

GLP-1: Assay to Aggregates

Master GLP-1 peptide analysis (semaglutide, tirzepatide). Discover RP-HPLC and SEC workflows for assay, related substances, degradation, and aggregates

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