<p><strong>We are pleased to invite you to our upcoming free online webinar on June 11, 2026 focused on one of the most pressing challenges in environmental monitoring and water quality management — PFAS (Per- and Polyfluoroalkyl Substances).</strong></p><p>As regulatory frameworks continue to evolve and compliance deadlines approach, laboratories, water utilities, and environmental professionals need robust, reliable, and cutting-edge analytical solutions to stay ahead.</p><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://events.teams.microsoft.com/event/91d97003-fe33-4dca-b80b-160d9f8a5655@485ca04e-6f74-4050-9764-cdb4bfa89c25"><strong>Registration HERE</strong></a></p></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_analyzy_PFAS_a9e4a87fbc.jpg" alt="ALS: Advanced PFAS Analytical Services " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_analyzy_PFAS_a9e4a87fbc.jpg 245w," sizes="100vw" width="600" height="336"></p><h4><strong>🎤 Our Speaker</strong></h4><p>The webinar will be hosted by <strong>Jana Kováčová, Ph.D., PFAS Regional Lead for Continental Europe Environmental Division</strong>, who has dedicated the last several years to the field of PFAS analysis and determination in ALS laboratories. Jana is a recognized expert in PFAS environmental analytics and will share practical insights and the latest developments in analytical strategies to help your organization achieve and maintain compliance.</p><h4><strong>🎯 What You Will Learn</strong></h4><ul><li>Latest <strong>regulatory developments</strong> and compliance requirements for PFAS in water, including <strong>EU Drinking Water Directive 2020/2184</strong> and its implications for water suppliers and laboratories.</li><li><strong>Regulatory updates for surface water and groundwater</strong> — what's new and what to expect next.</li><li>Overview of <strong>advanced analytical strategies</strong> for PFAS detection and quantification in water matrices and how we analyse PFAS samples.</li><li>Key <strong>analytical challenges</strong> associated with PFAS testing — from ultra-trace detection to matrix interferences and contamination control.</li><li>The critical importance of using tested <strong>sampling containers</strong> and sample preservation to ensure reliable results.</li><li>Illustrative <strong>examples of results</strong> from real-world PFAS water analyses.</li><li>How ALS can support your needs with <strong>accredited PFAS testing services</strong>.</li></ul><h4><strong>👥 Who Should Attend</strong></h4><p>This webinar is designed for our clients, professionals, laboratory and technical staff, scientists, as well as anyone with an interest in analytical chemistry who wants to better understand the occurrence of these "forever chemicals" in the environment. &nbsp;</p><h4><strong>💬 Q&amp;A Session</strong></h4><p>There will be a live Q&amp;A session at the end of the webinar. You are welcome to submit your questions in advance during registration or ask them live on the day.</p><h4><strong>📅 Additional Webinar Info:</strong></h4><ul><li><strong>Platform: </strong>Microsoft Teams (online)</li><li><strong>Time: </strong>10:00 CEST</li><li><strong>Language: </strong>English</li><li><strong>Duration:</strong> approx. 45 - 60 minutes (incl. Q&amp;A)<br>Extras: If you are unable to attend on the day, please register and we will provide you with the recording of the webinar.</li></ul><h4><strong>🔬 About ALS Environmental</strong></h4><p>ALS is a global leader in environmental testing and analytical services, providing accredited PFAS analysis to clients across Europe and beyond. Our dedicated PFAS experts help clients navigate the complex regulatory landscape with confidence.</p><blockquote><p>For further information, please contact us on: <strong>marketing.cz@alsglobal.com</strong></p></blockquote><p>We look forward to welcoming you to this important discussion on PFAS compliance in water.</p>

Invitation to the ALS Webinar PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

News from LabRulezLCMS Library - Week 23, 2026

<p><strong>Solvent switching is the process of changing the solvent contained within a liquid chromatography (LC) column. This procedure must be performed carefully to avoid irreversible damage to the column.</strong></p><p>The topic originates from a common customer question:</p><blockquote><p>“My column arrived in hexane, but I need to use it with water and acetonitrile. How do I switch the solvents in the column?”</p></blockquote><p>This article explains the solvent switching process, how to determine the solvent currently inside a column, how to select an appropriate transition solvent, and why proper solvent switching is essential.</p><h2><strong>Step 1: Determine the Shipping Solvent</strong></h2><p>Before changing solvents, it is important to know which solvent or mobile phase is already present in the column.</p><p>This information can typically be found in:</p><ul><li>The column care guide</li><li>The Certificate of Quality Assurance (CQA)</li></ul><h4><strong>Using the Column Care Guide</strong></h4><p>The column care guide is usually available on the manufacturer's website under the specific column brand.</p><ul><li>In the <strong>Shipping Solvent</strong> section, users can identify the solvent in which each phase is supplied.</li><li>The <strong>Mobile Phase Compatibility</strong> section can be used to determine whether the phase has any mobile-phase limitations beyond pH restrictions.</li></ul><h4><strong>Using the Certificate of Quality Assurance (CQA)</strong></h4><p>The CQA also provides useful information.</p><p>Under the <strong>Test Conditions</strong> section, the mobile phases used to test the column are listed.</p><ul><li>In the example shown in the video, a Luna column was tested using:<ul><li>75% acetonitrile</li><li>25% water</li></ul></li></ul><p>The testing conditions are often the same as the shipping solvent conditions, although this is not always the case.</p><p>If uncertainty remains, the recommendation is to contact the column manufacturer directly.</p><h3><strong>Step 2: Check Solvent Miscibility</strong></h3><p>Once the shipping solvent is known, the next step is to verify whether it is miscible with the mobile phases used in the analytical method.</p><p>A solvent miscibility chart can be used for this purpose.</p><h4><strong>Water and Immiscible Solvents</strong></h4><p>The video highlights that water is immiscible with several commonly used LC solvents, including:</p><ul><li>Hexane</li><li>Dichloromethane (DCM)</li><li>Heptane</li></ul><p>These solvents are commonly used under normal-phase conditions.</p><h4><strong>Isopropanol as a Transition Solvent</strong></h4><p>The video identifies <strong>isopropanol (IPA)</strong> as a solvent that is miscible with all LC solvents shown in the chart.</p><p>Because of this property, IPA is commonly used as an intermediate or transition solvent when switching between:</p><ul><li>Water and hexane</li><li>Water and heptane</li></ul><h3><strong>Step 3: Perform the Solvent Switching Procedure</strong></h3><p>After selecting an appropriate transition solvent, the solvent exchange can begin.</p><p>The procedure described in the video consists of the following steps:</p><h4><strong>1. Flush with the Transition Solvent</strong></h4><p>Flush the column with the selected transition solvent for:</p><ul><li>30–60 column volumes</li></ul><h4><strong>2. Flush with the Pure Starting Solvent</strong></h4><p>After the transition solvent, flush the column with:</p><ul><li>10 column volumes of the pure starting solvent</li></ul><h4><strong>3. Equilibrate with the Method Mobile Phase</strong></h4><p>Finally, equilibrate the column using the mobile phases required for the analytical method.</p><h3><strong>Example Solvent Switching Protocol</strong></h3><p>The video provides the following example.</p><h5><strong>Initial Column Solvent</strong></h5><ul><li><strong>The column arrives packed in:</strong><ul><li>99% hexane</li><li>1% acetonitrile</li></ul></li></ul><h5><strong>Transition Solvent</strong></h5><ul><li><strong>Use:</strong><ul><li>Isopropanol (IPA)</li></ul></li><li><strong>Flush the column with IPA for:</strong><ul><li>30–60 column volumes</li></ul></li></ul><h5><strong>Intermediate Step</strong></h5><ul><li><strong>Flush with:</strong><ul><li>10 column volumes of acetonitrile</li></ul></li></ul><h5><strong>Final Equilibration</strong></h5><ul><li><strong>Equilibrate with one of the following:</strong><ul><li>50% acetonitrile / 50% water</li><li>50% acetonitrile / 50% buffered water</li></ul></li></ul><h3><strong>Why Proper Solvent Switching Is Important</strong></h3><p>The video emphasizes that improper solvent switching can cause irreversible column damage.</p><p>Potential issues include:</p><h4><strong>Formation of Voids and Pockets</strong></h4><p>Immiscible solvent transitions can create:</p><ul><li>Pockets within the packed bed</li><li>Voids at the column inlet</li></ul><p>These defects can permanently damage column performance.</p><h4><strong>Salt Precipitation</strong></h4><p>If buffered mobile phases are involved and pure solvents are not used appropriately during the transition, salts may precipitate from solution.</p><h4><strong>Damage to Pressure-Sensitive Polymer Media</strong></h4><p>Pressure-sensitive polymer-based media may burst during improper solvent transitions.</p><h4><strong>Stripping of Coated Phases</strong></h4><p>Columns containing coated stationary phases or coated ligands may experience removal of these coatings during unsuitable solvent changes.</p><h3><strong>Irreversibility of Column Damage</strong></h3><p>According to the video, once damage caused by immiscible solvent exposure occurs, it is extremely difficult—if not impossible—to reverse.</p><p>For this reason, solvent changes should always be performed through an appropriate intermediate solvent whenever required.</p><h3><strong>Conclusion</strong></h3><p>Successful solvent switching begins with identifying the solvent in which the column was shipped. The miscibility between the shipping solvent and the intended mobile phases must then be evaluated. When immiscible solvents are involved, an appropriate transition solvent such as isopropanol should be used.</p><p>Following a controlled sequence of flushing, intermediate solvent exchange, and equilibration helps prevent permanent column damage and ensures safe operation of the chromatographic column.</p>

Solvent Switching in Liquid Chromatography Columns: How to Change Column Solvents Safely

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<h3><strong>Pharma and biopharma fundamentals masterclasses</strong></h3><h5><strong>Build confidence in your analytical decisions across pharma and biopharma workflows</strong></h5><p>The pharma and biopharma fundamentals masterclasses are a year-long educational series designed for scientists who want to strengthen their knowledge, compare analytical strategies, and apply best practices across regulated workflows.</p><p>Each session focuses on a real analytical challenge — from quantitation and metabolite identification to biopharma characterization and extractables and leachables — with practical guidance from SCIEX experts.</p><p>Attend live or watch on demand and choose the sessions most relevant to your work.</p><h4><strong>Available now:</strong></h4><h5><strong>Pharma fundamentals: Metabolite Identification Metabolite identification is essential in drug discovery, supporting confident decisions in compound design and toxicology</strong></h5><p>This session shows how alternative fragmentation strategies can overcome limitations of traditional CID and improve MetID accuracy for complex metabolites.</p><ul><li><strong>Speaker: </strong>Heather Chassaing, Senior Accurate Mass Workflow Specialist, SCIEX</li></ul><h4><strong>Upcoming sessions</strong></h4><h5><strong>2. Biopharma fundamentals: Fragment analysis by CE</strong></h5><p>This masterclass introduces protein fragment analysis using capillary electrophoresis, with a focus on CE-SDS in biopharmaceutical workflows. Learn the core principles behind size-based separation, along with practical guidance on sample preparation, method optimization, and data interpretation to support reliable characterization and quality control in regulated biopharma environments.</p><blockquote><p><strong>Speaker:</strong> Stephen Lock, Sr. Market Development Manager – Biopharma, SCIEX</p><p>Steve obtained his PhD in Physical Organic Chemistry from the University College of Swansea in 1993 and is a chartered chemist and a member of the Royal Society of Chemistry. He has worked for SCIEX in various technical roles for over 20 years and has presented at over 80 international meetings around the world. He currently works closely with customers in the biopharmaceutical industry. Steve is also currently an Adjunct Professor at the University of Pannonia.</p></blockquote>

SCIEX: Pharma and biopharma fundamentals masterclasses

Biopharma fundamentals: Fragment analysis by CE

Biopharma masterclass on fragment analysis by CE-SDS, covering protein separation, method optimization, and QC in regulated environments.

<p><strong>In the third webinar of the Small Molecules, Big Impact series, we will explore how MaxPeak Premier Columns are being applied in discovery workflows, with real-world examples of recently approved drug compounds analyzed using this technology.</strong></p><p>Attendees will see how improved surface chemistry can enable more accurate and reliable characterization of in-flight drug products, helping scientists generate high-quality chromatographic data when it matters most. This session is designed for analytical scientists supporting discovery programs who want a deeper understanding of current LC technologies on the market and how MaxPeak Premier Columns can be leveraged to strengthen confidence in their analytical results. Examples will also be given to how Waters technologies can improve throughput using ultra-short columns.</p><h4><strong>Who should attend</strong></h4><ul><li>Analytical scientist supporting discovery groups.</li></ul><h4><strong>Why you should attend</strong></h4><ul><li>Understand how MaxPeak Premier Columns can be used to improve. characterization of new and in-flight drug compounds during discovery workflows</li><li>Review examples of recently approved drugs analyzed with MaxPeak Premier technology and the resulting improvements in chromatographic performance.</li><li>Learn where and how to apply MaxPeak Premier Columns within discovery.&nbsp;</li></ul><h4><strong>What you will walk away with</strong></h4><ul><li>A stronger understanding of how MaxPeak Premier Columns can help characterize new compounds more easily and accurately.</li><li>Expert insights and perspectives on applying this technology to real-world drug development challenges.</li><li>Access to resources that enable you to further evaluate and research MaxPeak Premier technology for your own analytical workflows.</li><li>Learn practical strategies for increasing throughput in discovery experiments, including the use of ultra-short UPLC columns.</li></ul><blockquote><p><strong>Speaker: </strong>Kenneth Berthelette (Principal Scientist, Waters Corporation)</p><p>Ken earned his Bachelor of Science in Professional Chemistry from Bridgewater State University in Bridgewater, Massachusetts in 2010.</p><p>He joined Waters Corporation in March 2012, where he contributed to multiple product launches as part of the Research and Development team. In 2021, Ken transitioned into a role supporting Chemistry Aftermarket initiatives.</p><p>With a strong focus on applications and customer education, he has delivered numerous seminars and webinars covering topics such as method development, method modernization and transfer, HILIC separation techniques, and LC system troubleshooting.</p></blockquote>

Enhancing Next-Gen Drug Discovery with High-Performance Inert LC Solutions

Discover how MaxPeak Premier Columns improve LC analysis of new drugs, enhancing accuracy, performance, and throughput in discovery workflows.

Next-Gen Drug Discovery with Inert LC Solutions

<p><strong>Bringing innovative antibody therapeutics to market quickly requires more than upstream efficiency. It demands adaptable and robust downstream purification strategies.</strong></p><p>As novel mAb formats increase in complexity, purification challenges grow. Achieving required purity and yield often extends beyond traditional 2–3 step platform processes, requiring expanded chromatography options and optimized buffer systems.</p><h5><strong>In this webinar, we will discuss:</strong></h5><ul><li>Practical strategies for designing a flexible downstream purification toolkit</li><li>Approaches to buffer optimization for challenging antibody molecules</li><li>Ways to streamline process development while maintaining performance</li></ul><p>Register to learn how a well-designed purification toolkit can help accelerate development timelines and improve process robustness.</p><blockquote><p><strong>Speaker:&nbsp;</strong>Chantelle Gaskin (Field Application Scientist, Purification, Thermo Fisher Scientific)</p><p>Chantelle Gaskin is a Field Applications Staff Scientist specializing in protein and viral vector purification. She previously held leadership roles at Applied Genetic Technology Corporation and Brammer Bio before joining Thermo Fisher Scientific in 2020. With over 10 years of gene therapy experience, she has extensive knowledge of industry practices and regulatory standards, contributing to therapies for ocular, CNS, and systemic diseases. Chantelle holds a Master’s in Chemistry from the University of Florida and a Bachelor’s from Smith College.</p><p><strong>Speaker:</strong> Carlos Ferrero (Field Application Scientist, Thermo Fisher Scientific)</p><p>Biotechnology graduate from Madrid with a Master’s in Biochemical Engineering from London. He brings over 5 years of experience in the biopharmaceutical industry—over three years in downstream manufacturing and two years as a Field Application Scientist specializing in process liquids at Thermo Fisher Scientific. Passionate about bridging technical expertise with real-world application to support innovation in bioprocessing.</p><p><strong>Speaker:</strong> Ryan Hubbell (Product Manager, Process Liquids, Thermo Fisher Scientific)</p><p>Ryan Hubbell serves as the Associate Product Manager for Process Liquid Preparation Services at Thermo Fisher. He has professional experience in Quality Control, Operations, and Clinical Research. Ryan holds a master’s degree in biomedical engineering and is set to complete his MBA in May 2025.</p></blockquote>

Thermo Fisher Scientific: Supporting Efficient mAb Development with a Flexible Downstream Purification Toolkit

Supporting Efficient mAb Development with a Flexible Downstream Purification Toolkit

Optimize downstream purification for complex mAb formats. Learn buffer and chromatography strategies to streamline development and boost yield

Flexible Downstream Toolkit for Efficient mAb Development

<div><p><strong>Persistent challenges in RNA manufacturing—such as immunogenic double-stranded RNA (dsRNA) impurities and unreliable quantitation methods—can limit product quality, scalability, and confidence in process decisions. These bottlenecks are increasingly critical as RNA is applied beyond vaccines into therapeutics and gene editing.</strong></p><p>This webinar explores practical strategies to reduce immunogenicity and improve RNA quality across manufacturing workflows. Attendees will gain insight into how purification and analytical approaches can enhance consistency and yield, alongside advances in quantitation methods that enable more reliable measurement.&nbsp;</p><p>Join to better understand how to optimize RNA purity and analysis to strengthen process control and downstream success.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>Identify and characterize dsRNA impurities in RNA manufacturing workflows</li><li>Apply purification strategies to reduce immunogenic byproducts and improve RNA quality across applications</li><li>Evaluate and validate analytical methods for accurate and reliable RNA quantitation</li><li>Use decision frameworks to integrate purification and measurement approaches for scalable, reproducible manufacturing</li></ul><blockquote><p><strong>Presenter:</strong> Nathaniel Clark, PhD ( Senior Scientist at Repligen Corporation)</p><p>Dr. Nathaniel Clark is a senior scientist at Repligen. He has a doctorate in biochemistry and structural biology from UMass Amherst and studied RNA as a postdoctoral researcher at the University of Texas. At Repligen, he uses structural biology, protein engineering, and modeling to design novel affinity resins.</p></blockquote></div>

Repligen: Improving RNA Purity and Measurement for Reliable Bioprocessing

Improving RNA Purity and Measurement for Reliable Bioprocessing

Optimize RNA purity and analysis. Learn to reduce immunogenic dsRNA impurities and validate analytical methods for reliable quantitation in RNA manufacturing

Improving RNA Purity and Measurement for Bioprocessing

<p><strong>Ion chromatography remains central to environmental water analysis, but the way established methods such as EPA 300 A/B and perchlorate are being applied today has evolved. Advances in eluent generation, column design, and system configuration are changing how laboratories approach sensitivity, robustness, and method reliability often without formally changing the method itself.</strong></p><p>This webinar focuses on recent, practical developments in the most widely used environmental IC applications. Topics include updated perchlorate workflows using potassium hydroxide eluents, modernized EPA 300 A/B approaches enabled by the most current column formats, and emerging strategies for haloacetic acid (HAA) analysis. The discussion goes beyond method names to examine how implementation options influence performance in routine laboratory use.</p><p>The session will be led by Metrohm IC experts Jay Gandhi and Linx Waclaski, who bring extensive hands‑on experience supporting environmental laboratories and developing practical IC workflows for regulated water analysis. Drawing from real‑world method optimization, troubleshooting, and application support, the speakers will connect today’s IC hardware and column advances to the challenges labs encounter every day. Attendees can expect technically grounded guidance that goes beyond theory, with insights shaped by direct experience helping environmental labs improve method performance, reliability, and efficiency.</p><h4><strong>Key Learning Objectives:</strong></h4><ul><li>Optimize IC methods for key environmental applications, including perchlorate, EPA 300 A/B, and haloacetic acids (HAAs)&nbsp;</li><li>Apply best practices to improve data quality, robustness, and reproducibility&nbsp;</li><li>Compare eluent and column strategies, including carbonate vs. hydroxide (KOH) workflows&nbsp;</li><li>Identify opportunities to increase sample throughout</li></ul><h4><strong>Who Should Attend:</strong></h4><ul><li>Environmental lab analysts performing water analysis by ion chromatography</li><li>Lab managers and supervisors seeking to improve data quality, robustness, and consistency</li><li>Laboratories looking to increase sample throughput and reduce analysis time</li><li>IC users interested in optimizing methods, including modern column strategies</li></ul><blockquote><p><strong>Speaker: </strong>Jay Gandhi, Ph.D. (Vertical Market Manager, Metrohm USA)</p><p><strong>Speaker:&nbsp;</strong>Linx Waclaski (Product Manager for Ion Chromatography, Metrohm USA)</p><p><strong>Speaker:</strong>&nbsp;Melissa O'Meara (Forensic Science Consultant, ACS Media Group)</p></blockquote>

Metrohm: New Approaches to Established Environmental IC Methods

New Approaches to Established Environmental IC Methods

Optimize environmental water analysis by ion chromatography. Learn advanced column strategies and workflows for perchlorate, EPA 300 A/B, and HAAs.

<p><strong>In this webinar, Fred Foster, Applications Scientist at GERSTEL, Inc., will introduce GERSTEL’s automated sample preparation systems, then transition to a multi-omics presentation by Noah Smeriglio, Ph.D. Candidate in Chemistry, and Gwangbin Lee, Ph.D. in Chemistry, Postdoctoral Associate at the University of Maryland.</strong></p><p>This presentation will highlight an automated, integrated multi-omics workflow for extracting proteins, lipids, and metabolites from a single sample using the GERSTEL MPS platform. Validated across cell and tissue samples and coupled with LC-MS/MS analysis, the workflow enables reproducible, high-throughput multi-omics studies in complex biological applications.</p><h5><strong>You will learn how to:</strong></h5><ul><li>Optimize key parameters in your workflow</li><li>Improve recovery and reproducibility of proteins, lipids, and metabolites</li><li>Increase throughput for complex biological samples</li></ul><h5><strong>Full Abstract</strong></h5><p>Mass-spectrometry-based omics technologies have enabled the comprehensive characterization of diverse types of molecules, such as proteins, lipids, and metabolites, across biological systems. Integration of multiple molecular classes from the same sample reduces variability and enables system-level insights into biology and disease. However, conventional sample preparation methods using Folch or MTBE extraction are labor-intensive, susceptible to variability, and difficult to scale for high-throughput applications. Here, we developed an automated and integrated multi-omics sample preparation workflow using the GERSTEL MPS platform. Key experimental parameters were systematically optimized to achieve robust and reproducible recovery of proteins, lipids, and metabolites from a single sample. The workflow was validated across both cell and tissue samples, demonstrating strong reproducibility and scalability. Coupled with LC-MS/MS analysis, this platform was used to analyze over 60 brain samples from a neurodevelopmental disorder mouse model, achieving the identification and quantification of over 10,000 proteins, 2,000 lipids, and 700 metabolites. In summary, this automated multi-omics workflow provides a robust and scalable solution for high-throughput MS-based multi-omics studies.</p><blockquote><p><strong>Presenter: </strong>Fred Foster (Applications Scientist, GERSTEL, Inc.)</p><p><strong>Presenter: </strong>Noah Smeriglio, Ph.D. (Candidate, Chemistry, University of Maryland)</p><p><strong>Presenter: </strong>Gwangbin Lee (Postdoctoral Associate, Ph.D. in Chemistry, University of Maryland)</p></blockquote>

GERSTEL: An Automated Sample Preparation Platform for Integrated Proteomics, Lipidomics, and Metabolomics

An Automated Sample Preparation Platform for Integrated Proteomics, Lipidomics, and Metabolomics

Automate multi-omics sample prep. Learn to extract proteins, lipids, and metabolites from a single cell or tissue sample using the GERSTEL MPS platform

Automated Sample Prep for Multi-Omics Workflows

<h4><strong>Key Learning Points</strong></h4><ul><li>Understand the correct steps to take when first receiving a new column, including inspection procedures and initial test runs.</li><li>Learn practical techniques to extend column lifetime and maintain performance over time.</li><li>Identify when a column should be retired by recognizing key end-of-life indicators.</li><li>Apply best practices for column conditioning, activation, and proper storage.</li></ul><h4><strong>Who Should Attend</strong></h4><p>Any analysts and scientists routinely working with HPLC/UHPLC columns who want practical care, maintenance, and lifetime‑extension tips.&nbsp;</p><blockquote><p><strong>Presenter: </strong>Duilio Romanello (Senior Technical Specialist, Phenomenex)</p><p>Duilio Romanello earned his MSc in Pharmaceutical Chemistry and Technology from the University of Bologna. He joined Phenomenex in 2008 as an Inside Technical Sales Consultant, later leading GC/SPE and Env/Food teams in Italy. Since 2016, he has been Account Manager for Southern Italy and GC Specialist. In 2023, he became Senior Technical Specialist for Phenomenex’s Technical team supporting scientists globally with method development, troubleshooting, and application support.</p></blockquote>

Phenomenex: Tips for Getting the Best Out of Your LC Phenomenex Column

Tips for Getting the Best Out of Your LC Phenomenex Column

Discover best practices for HPLC/UHPLC column care, conditioning, storage, troubleshooting, and lifetime extension.

Getting Best Out of Your LC Phenomenex Column

<p><strong>Join us for an insightful webinar exploring reliable quantitation of GLP 1 analogues in bioanalysis and IP 2026 updates.</strong></p><p>This session will cover the strategic approaches for robust quantitation of GLP 1 analogues, emphasizing control strategy and method robustness over sensitivity. It also covered challenges such as matrix effects and analyte instability, along with key updates on Indian Pharmacopoeia monograph development, harmonization, and global recognition. in short as per the guideline's</p><blockquote><p><strong>Speaker: </strong>Dr. Pankaj Partani (Head-Application Support at SCIEX, PhD in Pharmaceutical Sciences)</p><p><strong>Key highlights</strong></p><ul><li>Robust GLP 1 quantitation is not about pushing limits—it’s about making the right strategic choices at every step.</li><li>Reliable GLP 1 data is built on control strategy, robustness, not just sensitivity.</li><li>Challenges in GLP 1 quantitation arise from matrix effects, instability, and non specific losses, not instrument capability.</li></ul><p>Dr. Gaurav Pratap Singh Jadaun, Ph.D. (Senior Principal Scientific Officer<br>Indian Pharmacopoeia Commission, Ghaziabad)</p><p><strong>Key highlights</strong></p><ul><li>The monograph development process</li><li>Their revision and harmonization, updates of the general chapters, international recognition of the IP, and IP Online portal</li></ul></blockquote>

SCIEX: Reliable quantitation of GLP‑1 analogues in bioanalysis and IP 2026 updates

Reliable quantitation of GLP‑1 analogues in bioanalysis and IP 2026 updates

Join us for an insightful webinar exploring reliable quantitation of GLP 1 analogues in bioanalysis and IP 2026 updates.

Quantitation of GLP‑1 analogues in bioanalysis

<p><strong>Migrating legacy LC Method doesn't have to introduce risk</strong></p><p>In regulated QC environments, LC method migration requires confidence, consistency, and control. This webinar explores how a structured, automated approach can help QC laboratories transition legacy LC methods to Alliance™ iS while maintaining compliance, method integrity, and operational continuity.</p><h5><strong>What you will learn</strong></h5><ul><li>How an automated Empower™ workflow enables confident, compliant migration of legacy LC methods to Alliance™ iS in regulated QC environments</li><li>Best practices for transitioning legacy LC methods while preserving method intent, system suitability, and data integrity</li><li>How a risk‑based migration strategy can support long‑term QC efficiency, performance, and laboratory scalability</li></ul><h5><strong>Who should attend</strong></h5><ul><li>Analyst, Supervisors and Lab Managers working in QC Pharmaceuticals Quality Control Labs<br>&nbsp;</li></ul><blockquote><p><strong>Presenter: </strong>Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)</p><p>Andrea Gheduzzi, is a principal LC market development manager for EMEA at Waters Corporation. Andrea Gheduzzi has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab manager position, and technical manager for chromatography columns.</p><p>He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his previous role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications.</p><p>Since 2023 he became principal LC market development manager for EMEA and member of the AQbD working party at the EDQM.</p></blockquote>

Waters Corporation: De‑Risking LC Method Migration: Transitioning Legacy Methods to Alliance™ iS System in Regulated QC Labs

De‑Risking LC Method Migration: Transitioning Legacy Methods to Alliance™ iS System in Regulated QC Labs

Smooth LC method migration to Alliance iS. Discover automated Empower workflows to maintain compliance and data integrity in regulated pharma QC labs

De‑Risking LC Method Migration

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Join us for a free, hands-on Thermo Scientific™ Proteome Discoverer™ software online workshop. This session is designed to walk you through the latest best practices for Data Independent Acquisition (DIA) analysis, featuring the powerful new DIA-NN node.</strong></p><p>Whether you are a novice or an intermediate user, this workshop provides the practical knowledge needed to leverage the novel InfinDIA mode for ultra-fast analysis against unlimited search spaces</p><h4><strong>What We’ll Cover</strong></h4><ul><li><strong>Proteome Discoverer 3.3 SP1 updates: </strong>A deep dive into the latest release, including news, installation, and licensing.</li><li><strong>DIA-NN &amp; InfinDIA:</strong> Guest speaker Vadim Demichev introduces DIA-NN 2.5 and the breakthrough InfinDIA mode for handling near-unlimited search spaces and selected applications.</li><li><strong>Practical processing walkthrough: </strong>Michaela Scigelova leads a step-by-step guide using DIA-NN:<ul><li>training materials, study, analysis</li><li>workflow parameter settings</li><li>DIA-NN node (discussion of all parameters, recommendet settings)</li><li>Results review</li></ul></li><li><strong>Tips for efficient data processing</strong></li></ul><p><i>Can’t attend the live broadcast? Register anyway! All registrants will receive a link to the session recording.</i></p><blockquote><p><strong>Presenter: </strong>Michaela Scigelova (Product Support, Thermo Fisher Scientific)</p><p>Michaela provides customer support to Thermo Scientific Proteome Discoverer software users.</p><p><strong>Presenter: </strong>Vadim Demichev (MSTARS Group Leader, Charité - Universitätsmedizin Berlin)</p><p>Vadim Demichev is a founder of Aptila Biotech and a research group leader at the Charité – Universitätsmedizin Berlin, focusing on developing of LC-MS methods and data analysis approaches for quantitative proteomics.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Join this workshop to explore DIA-NN, InfinDIA, and Proteome Discoverer 3.3 SP1 for efficient DIA proteomics data analysis and review.

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