<p><strong>In many laboratories, researchers rely on </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1759"><strong>Thermo Scientific Compound Discoverer software </strong></a><strong>for untargeted and small molecule research. It excels at digesting raw data, uncovering unknowns, and identifying compounds with speed, flexibility and confidence. But when it comes to regulated environments, compliance and reporting are critical; that’s where </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon software</strong></a><strong> comes in.</strong></p><p>&nbsp;</p><p>Historically, moving results between the two meant: numerous manual steps, added time, increased risk of error, and a big gap between discovery research and regulated compliance.</p><p>With <strong>Chromeleon version 7.4 software and Compound Discoverer version 3.5 software </strong>that gap process is more streamlined.</p><h3><strong>How it works</strong></h3><h4><strong>1. Compliant MS data acquisition.</strong></h4><p>Chromeleon software manages all aspects of chromatography and mass spectrometry data acquisition, including:</p><ul><li>Instrument control (for LC, GC, MS, including single quadrupole, triple quadrupole and high-resolution accurate mass)</li><li>Automated sequences and sample preparation</li><li>Compliance-ready audit trails and electronic signatures</li><li>Centralized project and user management</li><li>Secure, traceable data storage ready for downstream processing</li></ul><h4><strong>2. Discovery and identification.</strong></h4><p>Raw data files can be transferred to Compound Discoverer software for advanced discovery and identification using powerful algorithms and a comprehensive suite of spectral libraries (like <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1764"><strong>mzCloud</strong></a>), chemical databases, fragment and neutral loss databases, and in-silico fragmentation prediction.</p><p>When discovery work is complete and finalized, Compound Discoverer software now has the option to export data as a Chromeleon list, giving users the option to export all ion types, base ion with fragments, or base ion with in-source fragments back to Chromeleon software.</p><h4><strong>3. Seamless return to Chromeleon software. &nbsp;</strong></h4><p>Chromeleon 7.4 software introduces an import mechanism that brings Compound Discoverer results directly into the software. Users can import the components within the Chromeleon List directly into the MS Component table of the processing method. This enables you to take the discovery work done in Compound Discoverer software, bring it into Chromeleon software, and generate reports in a fully compliant environment.</p><h3><strong>The benefits</strong></h3><ul><li><strong>Compliance you can trust:</strong> Chromeleon software provides the procedural controls, audit trails, and report generation that regulated labs demand.</li><li><strong>Discovery without compromise:</strong> Researchers can continue to use Compound Discoverer software for flexible data mining and confident compound identification.</li><li><strong>One holistic workflow:</strong> Instead of fragmented manual transfers, labs now have an end-to-end import/export mechanism connecting research and compliance.</li><li><strong>Identity confirmation across platforms:</strong> Evidence of spectra is available in both software, ensuring consistency and confidence in results.</li></ul><h3><strong>From discovery to decision</strong></h3><p>With this new connectivity, you no longer must choose between flexibility for research and rigor for compliance. Instead, you can perform advanced discovery work and seamlessly push results into Chromeleon software to finalize reports, meet procedural compliance, and share data with stakeholders.</p><p>It’s the best of both worlds: <strong>discovery and compliance, integrated.</strong></p><h3><strong>Learn More</strong></h3><p>Have questions or want to learn more? <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/chromatography-data-systems-cds/cds-software-built-mass-spectrometry.html">Contact us</a> to learn how this integrated approach can support your analytical goals, or take a look at our <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromelon software</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1759"><strong>Compound Discoverer software</strong></a> storefronts!</p><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a>&nbsp;#Chromeleon #CompoundDiscoverer #Software</p></blockquote>

Connecting Discovery and Compliance: Compound Discoverer Software Meets Chromeleon CDS

<p><strong>Proficiency testing (PT) is applicable to quantitative, qualitative and interpretative assessments, but this leaflet will concentrate on PTs for quantitative tests. Participation in PT is an essential part of the quality assurance in analytical laboratories and provides them with many benefits. In PT the provider evaluates the performance of participants against pre-established criteria defined in the design of the PT scheme.</strong></p><h4><strong>Performance evaluation&nbsp;</strong></h4><p>The majority of PT schemes involve some form of performance score, such as the <i>z</i> or similar scores<sup>1</sup> , and corresponding assessment criteria. An assigned value (<i>x<sub>pt</sub></i>) and a standard deviation for proficiency assessment (<i>s<sub>pt</sub></i>) are determined and used to calculate the performance score of the laboratory result (<i>x<sub>i</sub></i>), e.g. the <i>z</i> score with <i><strong>z = (x<sub>i</sub> - x<sub>pt</sub> ) / s<sub>pt</sub></strong></i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_How_can_proficiency_testing_help_my_laboratory_2_c1bf0b596f.jpg" alt="Eurachem: How can proficiency testing help my laboratory?" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_How_can_proficiency_testing_help_my_laboratory_2_c1bf0b596f.jpg 195w," sizes="100vw" width="952" height="761"></p><p>Assessment of <i>z</i> scores is based on the following criteria:&nbsp;</p><ul><li><strong>|</strong><i><strong>z</strong></i><strong>| ≤ 2.0</strong> is regarded as satisfactory;&nbsp;</li><li><strong>2.0 &lt; |</strong><i><strong>z</strong></i><strong>| &lt; 3.0</strong> is regarded as questionable (‘warning signal’);&nbsp;</li><li><strong>|</strong><i><strong>z</strong></i><strong>| ≥ 3.0</strong> is regarded as unsatisfactory (‘action signal’).&nbsp;</li></ul><p>This is based on the concept that normally distributed analytical results lie within <strong>two standard deviations with a probability of ca. 95 %</strong>, and within <strong>three standard deviations with a probability of 99.7 %</strong>.&nbsp;</p><p>PT providers have several options to determine <i>s<sub>pt</sub></i> such as prescribed/perceived desirable analytical performance or the observed distribution of data. The <i>s<sub>pt</sub></i> used by the PT provider may not be appropriate for all laboratories. If justified, the participants may then calculate their own <i>z</i> score using an alternative spt value which is fit for their purpose.&nbsp;</p><h4><strong>Corrective actions</strong></h4><p>Unsatisfactory performance scores (‘<strong>action signal</strong>’) indicate possible problems in the analysis undertaken. The laboratory must investigate this (e.g. by<strong> checking for transcription/calculation errors, trueness and precision</strong>) and, if necessary, address the problems through appropriate corrective actions. Participation in the PT provides very limited benefits to the laboratory, if unsatisfactory performance scores are not acted upon.</p><h4><strong>Evaluation of results over time&nbsp;</strong></h4><p>In addition to internal quality control, regular participation in PT enables laboratories to monitor their performance over time and to identify trends before these become problems. Performance scores obtained from subsequent PT rounds can be plotted in a control chart.&nbsp;</p><h4><strong>Method comparisons&nbsp;</strong></h4><p>Where PT schemes require participants to report details of the method used, the PT report may enable the participant to compare the performance of their method with that of other methods used.&nbsp;</p><h4><strong>Use of PT data to estimate bias&nbsp;</strong></h4><p>The bias of a method should be established using <strong>certified reference materials (CRMs)</strong> or comparison with a <strong>reference method.</strong> However, these may not be available for all matrices, analytes and levels, or CRMs may not be fully representative of the real test samples. Participation in PT provides the opportunity to check the bias taking into account the effects of matrix and concentration variation, provided that a reliable estimate of the “<strong>true value</strong>” is assigned in the PT. Participation in several PT rounds also provides information on the bias variability which can be used as a contribution in the laboratory evaluation of the measurement uncertainty.&nbsp;</p><h4><strong>Use of PT to check measurement uncertainties&nbsp;</strong></h4><p>The ζ (zeta) score can help to check the plausibility of the laboratory’s measurement uncertainty estimate. It is calculated as follows:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_zeta_score_calculation_b70d8b1187.jpg" alt="Eurachem: Zeta score calculation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_zeta_score_calculation_b70d8b1187.jpg 245w," sizes="100vw" width="423" height="188"></p><p>where <i>x<sub>i</sub></i> is the laboratory’s result, <i>x<sub>pt</sub></i> the assigned value, and <i>u(x<sub>i</sub>)</i> and <i>u(x<sub>pt</sub>)</i> are their respective standard uncertainties.&nbsp;</p><p>The assessment criteria for satisfactory, questionable and unsatisfactory results are the same as for the <i>z </i>score. The uncertainty reported by a laboratory for its measurement result is an estimate of the accuracy that the laboratory claims to reach. If <i>ζ</i> scores are outside the acceptable range, this shows that the laboratory is not able to fulfill its own requirements. In other words the measurement uncertainty is underestimated.&nbsp;</p><p>Additionally, the standard measurement uncertainty of a laboratory result can be expected to be lower than the reproducibility observed in the proficiency test. If the measurement uncertainty is much lower the uncertainty estimate should be reviewed.&nbsp;</p><h4><strong>Demonstration of competence&nbsp;</strong></h4><p>Successful participation in <strong>PT (| z | ≤ 2.0)</strong> is often seen as a proof of competence to customers, accreditation bodies and regulatory authorities. PT can also provide a valuable educational element to the laboratory, for example it can indicate the success of staff training or where additional training is required.&nbsp;</p><h4><strong>More information / further reading&nbsp;</strong></h4><p>B. Brookman and I. Mann (eds.) Eurachem Guide: Selection, Use and Interpretation of Proficiency Testing (PT) Schemes (3rd ed. 2021). Information about PT providers and schemes can be obtained from your national accreditation body, from the EPTIS website (www.eptis.org) or from other national or international organisations.</p>

How can proficiency testing help my laboratory?

<p><strong>The 44th International Symposium on Capillary Chromatography (ISCC), the premier meeting for pressure and electrodriven microcolumn separations and related techniques, will be held May 17 – 22, 2026 in the Congress Centre, Riva del Garda, Italy.</strong></p><p>The <strong>21st GCxGC Symposium</strong> will be organized jointly with the ISCC meeting to allow scientists to attend both meetings. The symposium will start with a short course on Sunday May 17 covering the fundamentals and applications of comprehensive GCxGC and with a plenary session on <strong>Monday May 18</strong>. Key-note lectures and posters will be included in the program of the ISCC meeting.</p><h3><strong>KeyDates</strong></h3><ul><li><strong>February 20, 2026: </strong>Abstract deadline for an Oral Presentation to be included in the Book of Abstracts.</li><li><strong>March 15, 2026:</strong> Abstract deadline for a Poster Presentation to be included in the Book of Abstracts.</li><li><strong>April 06, 2026: </strong>Within this date, information will be given on the acceptance of oral and poster presentations.<ul><li><i><strong>Please remember that if you are submitting an abstract for an oral or poster presentation, you must pay the registration fee by April 19, 2026 (with the reduced fee by April 12, 2026). If no payment is made by April 22, 2026, the abstract will not be included in the program and book of abstracts.</strong></i></li></ul></li><li><strong>April 12, 2026:</strong> Deadline for Reduced Registration</li><li><strong>April 22, 2026:</strong> Preliminary Program</li><li><strong>May 17, 2026:</strong> GCxGC and LCxLC Courses</li><li><strong>May 18, 2026:</strong> 21st GCxGC Symposium</li><li><strong>May, 19 2026:</strong> 44th ISCC Symposium</li></ul><h3><strong>Program</strong></h3><h4><strong>Invited Speakers 21st GCxGC</strong></h4><h5><strong>Beyond Resolution: GC×GC as an Enabler of Predictive, Purpose-Driven Analytical Science</strong></h5><ul><li>Chiara Cordero<ul><li>Chiara Cordero (orcid.org/0000-0003-3201-0775) is Full Professor of Food Chemistry at the Department of Drug Science and Technology, University of Turin (Italy). She was Research Fellow at the Deutsche Forschungsanstalt für Lebensmittelchemie (DFA), Technical University of Munich (Germany), and Visiting Professor at the Poznan University of Life Sciences (Poland, 2019 and 2023) and Stellenbosch University (South Africa, 2020).Her research focuses on the development of instrumental platforms based on comprehensive two-dimensional gas chromatography (GC×GC) for food-omics applications (profiling and fingerprinting), data processing tools for GC×GC interpretation, discovery of food quality markers (food metabolomics and volatilomics), and intake markers in biofluids (nutrimetabolomics and volatilomics). She also works on the design of miniaturized, fully automated, solvent-free sample preparation strategies for sensomic food characterization.In 2008, she received the “Leslie S. Ettre Award” for original research in capillary gas chromatography with emphasis on food and environmental safety. In 2014, she was awarded the “John B. Phillips Award” for achievements in GC×GC. In 2016, The Analytical Scientist included her in its “Women Power List” of the 50 most influential women in analytical science. In 2022, she received the Scientific Achievement Award in GC×GC, and in 2024, the “Giovanni Dugo Medal” from the Italian Chemical Society (GISS) for research in food analysis.</li></ul></li></ul><h5><strong>GC×GC-(HR)TOFMS Volatolomics: Advances in Disease Diagnosis</strong></h5><ul><li>Jean-François Focant<ul><li>Jean-François (Jef) Focant is Full Professor at the Chemistry Department at ULiege in Belgium. Expert in multidimensional GC coupled to MS, his team develops and validate analytical methods for the measurement of (semi)volatile molecules present in complex matrices. His Organic and Biological Analytical Chemistry Laboratory is known for its focus on solving real-life analytical challenges to serve the general society. The diversity of applications is very large and covers fields such as forensics, food control, archeology, and much more. Major recent activities include metabolomics (volatolomics, breathomics), especially oriented to biomarker discovery in medical applications. The team also specializes in specific chemometric solutions for feature selections over large data sets from multi-class studies.</li></ul></li></ul><h5><strong>Modulation in GC×GC: a journey over three decades</strong></h5><ul><li>Tadeusz Gorecki<ul><li>Tadeusz Górecki is a professor at the Department of Chemistry, University of Waterloo (ON). He obtained his M.Sc. Engineer (1981) and Ph.D. (1986) degrees from the Gdansk University of Technology, Poland, and the Professor of Chemical Sciences degree (2009) from the President of the Republic of Poland.Prof. Górecki’s main research area is separation science, with a particular focus on comprehensive multidimensional gas and liquid chromatography, as well as sample preparation and environmental analysis. He has authored/co‐authored 28 book chapters, over 180 papers published in peer reviewed journals, over 320 conference contributions (including nearly 100 invited presentations) and 6 patents.He is the recipient of the Waksmundzki Medal awarded by the Committee on Analytical Chemistry of the Polish Academy of Sciences. In 2017 he received the GCxGC Scientific Achievement Award at the 41st International Symposium on Capillary Chromatography &amp; the 14th GCxGC Symposium. His papers have been cited over 10000 times.</li></ul></li></ul><h5><strong>Preliminary feature extraction algorithm for comprehensive two-dimensional gas chromatography</strong></h5><ul><li>Leandro Wang Hantao<ul><li>Professor at the Institute of Chemistry, University of Campinas (UNICAMP). His research interests include sample preparation, comprehensive two-dimensional gas chromatography, mass spectrometry, and chemometrics.</li></ul></li></ul><h5><strong>Labrador vs. laboratory in arson investigations. GC×GC-TOFMS to the rescue</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=James+Harynuk"><strong>James Harynuk</strong></a><ul><li>Prof. James Harynuk is currently a Full Professor at the University of Alberta, Canada. His research focuses on developing advanced analytical tools to tackle challenges such as complex samples, faster analysis times, and lower detection limits.He specializes in multidimensional gas-phase separations, including GC×GC, heart-cut GC (GC-GC), and advanced data handling tools. Applications of his work span health research, metabolite profiling, forensic science, petrochemicals, and environmental science.</li></ul></li></ul><h5><strong>GC×GC-HRToFMS for the detection of organohalogen compounds in environmental samples</strong></h5><ul><li>Teruyo Ieda<ul><li>Teruyo Ieda is a senior researcher at the National Institute for Environmental Studies, Japan. Her research focuses on the development of detection methods for organohalogen compounds in environmental samples. Her research interests include comprehensive two-dimensional gas chromatography (GC x GC), high-resolution time-of-flight mass spectrometry (HRToFMS), sample preparation, and thermal desorption methods.</li></ul></li></ul><h5><strong>Using comprehensive GCxGC to improve the sensitivity and temporal resolution in food flavour analysis</strong></h5><ul><li>Hans-Gerd Janssen<ul><li>Prof. Hans-Gerd Janssen obtained his MSc degree in Chemical Engineering (1987, cum laude) and his PhD degree in analytical chemistry in 1991 (Supercritical Fluid Chromatography), both from the Eindhoven University of Technology. After obtaining his PhD degree he joined the Eindhoven University as an assistant professor and became associate professor in 1996. In 1999 he moved to Unilever R&amp;D where he currently is science leader Food Compositional Analysis. From 2004 to 2019 he was part-time professor at the University of Amsterdam at the chair ‘(bio-)macromolecular separations’. In 2019 he moved to Wageningen University where he now holds a part-time professor position in ‘recognition-based analytical chemistry’.Prof. Janssen has published more than 220 papers including four patents and seven book chapters. He is a member of the editorial advisory board of several scientific journals. He has been, or is, a member of the board of the Analytical Chemistry division of the Dutch Chemical Society and the working group Separation Methods. He also is a member of the scientific or organizing committee of several symposia including the Comprehensive GCxGC meetings, the conference series on Capillary Chromatography and the series Recent Advances in Food Analysis. His research interests are broad, ranging from theory development in chromatography to the development of advanced chromatographic systems for food analysis. Prof. Janssen was awarded the 2020 GC×GC scientific achievement award in recognition of his contribution to the field. In 2023 he received the AOCS Herbert Dutton Award for tis contribution to developments in the field of lipid analysis.</li></ul></li></ul><h5><strong>Innovations in GC×GC Modulator Design with 3D Printing, and Selected Novel Applications</strong></h5><ul><li>Philip Marriott<ul><li>Professor Marriott’s research commenced at LaTrobe University (Ph.D.), continued at Bristol (Postdoc) then had academic appointments at the National University of Singapore then in Melbourne at RMIT and Monash University. These latter two appointments accompanied invention of, and developments in cryogenic modulation in GC, leading to primary research in comprehensive two-dimensional GC (GC×GC), multidimensional GC (MDGC), and mass spectrometry.Our research includes device development, fundamental descriptions of GC×GC technology, and supports a broad applications base. As a platform technology, we apply MDGC and GC×GC to a diverse array of separations, including: pesticides; petrochemicals; pharmaceuticals; natural products; toxins; and foods, flavours and beverage analysis such as olfactometry, essential oils, wine, coffee, hop, fatty acids, polyphenols, food safety, herbs and spices etc. He has had visiting appointments in China, South Korea, Singapore, Brazil, and Malaysia.</li></ul></li></ul><h5><strong>LC-GC(×GC) a powerful toolbox in food analysis</strong></h5><ul><li>Giorgia Purcaro<ul><li>Giorgia Purcaro is a full professor of Analytical Chemistry at Gembloux Agro-Bio Tech, University of Liège (Belgium). She has a Ph.D. in Food Science from the University of Udine (Italy). She spent part of her postdoctoral work at the University of Messina (Italy) and at Dartmouth College (USA) before being appointed at Gembloux Agro-Bio Tech (Belgium) in 2018.Her main areas of research are the optimization of hyphenated chromatographic techniques and sustainable sample preparation workflows. The primary areas of application are related to contaminant analysis in food and food quality, with a primary focus on lipids and volatile compounds. Her primary goal is to demonstrate the robustness of hyphenated chromatographic techniques and facilitate their routine application, thereby ensuring more cost-effective, informative, and effective analytical methods.She has significantly contributed to the advancement in the field of MOSH and MOAH analysis in food, by developing an LC-GC×GC-FID/MS and the associated dedicated software in collaboration with LECO, and she is constantly improving the sample preparation method to increase accuracy in the determination.She received the Leslie Ettre Award in 2010 for her most outstanding contribution to capillary chromatography and the J. Phillips Award in 2015 for her contributions to the field of comprehensive two-dimensional GC. She was included in the list “Top40under40”.She has been a co-author of more than 150 papers and more than 300 conference presentations, with an H-index of 35.</li></ul></li></ul><h5><strong>Adapting Tile-based Discovery Analysis for Comprehensive Two-dimensional Gas Chromatography with Vacuum Ultraviolet Spectroscopy (GC×GC-VUV) Data of Gas Oils</strong></h5><ul><li>Robert E. Synovec<ul><li>Robert E. Synovec is a Professor of Chemistry at the University of Washington (UW) in Seattle WA, USA. He obtained his PhD in 1986 from Iowa State University under the direction of Edward S. Yeung, then joined the UW Faculty, also in 1986. At UW, he served as Associate Chair of the Chemistry Graduate Education Program from 2007-2020 and is now Co-Director of the MSACST Program (2022-present). Synovec has graduated 51 PhDs, 7 Thesis Masters, and 12 Non-Thesis Masters, with 10 Post Docs and 67 Undergraduate Researchers.His group pioneers the development of novel analytical instrumentation and methodology based upon chemical separation science, coupled with chemometric data analysis at both a fundamental and problem-solving level. He has over 300 publications (which includes over 75 publications in Analytical Chemistry, with an h-index of 60 and i10-index of 212), and over 680 research presentations which includes 280 invited lectures. The tile-based Fisher ratio software pioneered by the group to perform discovery-based analysis of GC×GC-TOFMS data was licensed by LECO corporation, commercialized as ChromaTOF Tile. In May 2013, Synovec was awarded the GC×GC Scientific Achievement Award at the 10th GC×GC International Symposium. This award has been instituted to recognize pioneering contributions in developing and promoting GC×GC instrumentation, method development and/or applications. In May 2016, Synovec received the Marcel Golay Award at the 40th ISCC meeting in Riva del Garda, Italy, presented to a scientist in recognition of a lifetime of achievement in capillary chromatography.</li></ul></li></ul><h5><strong>Major benefits of using comprehensive 2D gas chromatography-mass spectrometry in food analysis</strong></h5><ul><li>Peter Tranchida<ul><li>Peter Q. Tranchida occupies a position as Full Professor in Food Chemistry in the Department of Chemistry, Biological, Pharmaceutical and Environmental Sciences (University of Messina, Italy), and is currently Coordinator of the Master’s Degree Course in Food Science and Human NutritionHe has co-authored over 180 scientific publications (Scopus database) and has participated to over 360 oral/poster presentations in national and international meetings. In 2012, at the"9th GC×GC symposium", held in Riva del Garda, he was awarded the "John Phillips Award", for his outstanding achievements in the field of comprehensive two-dimensional gas chromatography. In 2019, at the “16th GC×GC symposium”, held in Fort Worth (Texas), he was awarded the “GC×GC Lifetime Achievement Award”. Prof. Tranchida is currently Associate Editor of Journal of Separation Science (Wiley).His research activities are focused mainly on the study of complex food samples by using advanced gas chromatography processes, in particular, multidimensional gas chromatography systems, combined with various forms of mass spectrometry Specifically, he has performed a great deal of research work in the field of classical multidimensional gas chromatography, multidimensional liquid-gas chromatography, and comprehensive 2D gas chromatography.</li></ul></li></ul><h3><strong>Short Courses</strong></h3><h4><strong>GC×GC Course</strong></h4><p>The popular GC×GC workshop Riva returns. In 2026, we will feature an updated coverage of basic principles, fundamentals, optimization strategies, key applications of GC×GC.</p><p>Presented by leading proponents of GC×GC, this course will offer opportunity to ask questions through a Q&amp;A session, share experiences, and learn of solutions that will assist your understanding of the technique, and provide tips and advice to improve your conduct of GC×GC.</p><p>Combined with a strong program of oral presentations and posters, GC×GC Riva 2026 promises to be a wealth of value-added information for the practitioner.</p><h5><strong>Target Audience</strong></h5><p>The target audience includes scientists and technologists who have an interest in GC×GC and are familiar with the technology but need additional information to assess the merits of GC×GC for their particular application or wish to further interpret the scope of GC×GC. More experienced users who wish to optimize their use of the instrument, to update their knowledge, or wish to have an opportunity to evaluate their personal practices in GC×GC will also be catered for.</p><h4><strong>Sunday - May 17, 2026</strong></h4><h5><strong>09:00 – 09:45 &nbsp;Introduction and Fundamentals</strong></h5><ul><li>Tadeusz Gorecki</li></ul><h5><strong>09:45 – 10:30 Optimization</strong></h5><ul><li>Hans-Gerd Janssen</li></ul><h5><strong>10:30 - 11:00 </strong>Coffee Break</h5><h5><strong>11:00 – 11:45 GCxGC Data</strong></h5><ul><li>James Harynuk</li></ul><h5><strong>11:45 – 12:45 Applications</strong></h5><ul><li>Philip Marriott</li></ul><h5><strong>12:45 - 13:00 Q/A Session</strong></h5>

21st GC×GC Symposium - Invited Speakers

Software

Article

Product

Events

Academy

Video

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

ISCC & GC×GC Symposium bring together global experts to discuss advances in capillary and multidimensional chromatography, mass spectrometry, and analytical technologies for complex sample analysis.

International Symposium on Capillary Chromatography (ISCC) and GCxGC Symposium

Separation Science

Agilent Technologies

Bruker

Shimadzu Corporation

Plasmion

Spectroscopy & Separation Science

<h3><strong>Direct screening enables fast identification and comparison of substances</strong></h3>
<p>Fast &amp; Direct Screening enables to identify or compare different substances without any sample preparation.</p>
<h3><strong>Screening with quantification delivers reliable concentration levels</strong></h3>
<p>Screening with quantification not only enables a fast identification of substances but also provides reliable information about concentration levels to compare with standards or thresholds.</p>
<h3><strong>Automated all-in-one workflow simplifies routine analytics</strong></h3>
<p>All-in-one-Workflow reduces effort and cost in routine analytics as it enables to only perform detailed GC-MS analysis for positively screened samples.</p>
<h4><strong>Conventional Ionization Technologies</strong></h4>
<p>With conventional atmospheric pressure methods, the ions are mostly <strong>formed outside the inlet of an MS</strong>. This implies that the substance to be analyzed (e.g. coffee) cannot be analyzed directly, but is usually &quot;sprayed&quot; into the MS in the form of a sample (liquid extract) via the ionization source.</p>
<h4><strong>SICRIT® Technology</strong></h4>
<p>The SICRIT® (Soft Ionization by Chemical Reaction In Transfer) ionization source is <strong>interfaced with</strong> the atmospheric pressure <strong>inlet of the MS</strong> and ionizes every substance which is drawn into the MS by its inherent vacuum.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Plasmion_Conventional_MS_Ionization_Technologies_vs_SICRIT_Technology_8999716e25/Plasmion-Conventional-MS-Ionization-Technologies-vs.-SICRIT(r)-Technology.png" alt="Plasmion: Conventional MS Ionization Technologies vs. SICRIT® Technology"/></p>
<h4><strong>SICRIT® Characteristics</strong></h4>
<ul>
<li>Simple extension of MS inlet</li>
<li>Concentric dielectric barrier discharge</li>
<li>Sample ionized during transfer into MS</li>
<li>Soft ionization by proton transfer and UV light</li>
<li>No consumables</li>
</ul>


Plasmion: Direct MS Screening - Get Results Faster with SICRIT

Direct MS Screening - Get Results Faster with SICRIT

<p><strong>Agilent and GERSTEL are happy to host this 4-day live virtual seminar discussing how you can assure safety, authenticity, and quality of alcoholic beverages. The focus will be on sharing the latest in technology developments and capabilities, new applications, and customer stories. Topics include spirits, wine, beer, and cider.  There is something for everyone in this seminar series and we are glad to see you here.</strong></p>
<h3><strong>Presentation 1: Characterizing free and bound monoterpene alcohols in wine fermentations</strong></h3>
<ul>
<li><strong>Presenter: Prof. Susan Ebeler</strong> (Professor, Department of Viticulture and Enology, University of California, Davis)</li>
<li><strong>Presenter: Dr. Larry Lerno</strong> (Director, Food Safety and Measurement Facility, University of California, Davis)</li>
</ul>
<p>Monoterpenes and their glycosidically boud pre-cursors contribute important aroma characteristics to many grape and wine varieties. This presentation will describe multi-dimensional approaches to characterize free and glycosidically-bound monoterpenes in grapes and wines. Glycosidically-bound terpenes are isolated from grapes and the aglycones identified by hydrolysis followed by SPME-GC/MS. The intact glycosides are tentatively identified by ultrahigh performance liquid chromatography quadrupole time of flight mass spectrometry (UHPLC-QTOF/MS). This work enhances understanding of the ways that monoterpenyl glycosides contribute to grape and wine volatile aroma composition.</p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>Role of free and glycosidically bound monoterpenes on grape and wine aroma and flavor.</li>
<li>Analytical approaches using SPME-GC/MS and UHPLC-QTOF/MS to identify and monitor glycosidically-bound monoterpenes in grapes and wines.</li>
<li>Information about impacts of fermentation conditions on glycosidically-bound monoterpenes in wine</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>Analytical chemists, food and wine chemists, anyone with interest in food and wine flavor and aroma</p>
<h3><strong>Presentation 2: Solventless Extraction Techniques for the Analysis of Wine</strong></h3>
<ul>
<li><strong>Presenter: Dr. John Stuff</strong> (Manager, Analytical Services Group, GERSTEL)</li>
</ul>
<p>This talk will focus on solventless extraction techniques for the analysis of wines. Examples of each technique will be presented. The advantages and disadvantages of each technique will be discussed.</p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>Different solventless extraction techniques for the analysis of beverages</li>
<li>Advantages and disadvantages of each technique</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>Anyone involved in the analysis of beverages, food, flavor or fragrances</p>
<h3><strong>Presentation 3: Effect of Winemaking on Element Profiles and Arsenic Species</strong></h3>
<ul>
<li><strong>Presenter: Dr. Jenny Nelson</strong> (Applications Scientist, Agilent Technologies)</li>
</ul>
<p>Metals and minerals play important roles in the production of wine and can impact the overall quality of the finished product. Although a wine’s element content is known to be influenced by environmental conditions originating in the vineyard, it is not entirely understood how winemaking processes impact the final metal concentrations. After a long 2 year study, we are ready to share findings on metals and minerals role in the production of wine and the impact on overall quality. The elemental content of wine is known to be influenced by environmental conditions originating at the vineyard, however, it is not known how winemaking processes impact the final metal concentrations.</p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>How metals and minerals play an important role in the production of wine.</li>
<li>How to use elemental fingerprinting for the geographic determination of wine.</li>
<li>How ICP-MS is used in the wine industry.</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>Anyone interested in elemental analysis of wine</p>
<blockquote>
<p><strong>Presenter: Prof. Susan Ebeler (Professor, Department of Viticulture and Enology, University of California, Davis)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Ebeler is a professor in the Department of Viticulture and Enology at UC Davis. She seeks to answer questions about food and beverage flavor, quality and health effects, using analytical tools including gas chromatography-mass spectrometry, and high-performance liquid chromatography-mass spectrometry, to study the effects of agricultural practices, fermentation, processing, and storage on composition of grapes, wines, and other foods and beverages.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Larry Lerno, PhD (Director, Food Safety and Measurement Facility, University of California, Davis)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Lerno is a specialist in the Department of Viticulture and Enology at UC Davis where he serves as the Director of Research of the UC Davis Food Safety and Measurement Facility. Dr. Lerno uses gas and liquid chromatography coupled to mass spectrometric detectors to explore the aroma, flavor, and taste compounds in foods and beverages and how agricultural, processing, and environmental factors may effect these compounds.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: John Stuff, PhD (Manager, Analytical Services Group, GERSTEL)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Stuff’s is currently Manager of the Analytical Services Group with GERSTEL, Inc in Baltimore, MD. He is responsible for methods development for sample preparation and introduction for gas chromatography-mass spectrometry. He develops and teaches customer training classes, gives seminars and posters at national and international meetings, conducts new product testing, and supports pre- and post-sales opportunities. He provides expert analytical support to a wide customer base including, food, flavor, fragrance, forensic, environmental, and chemical industries.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Jenny Nelson, PhD (Application Scientist, Agilent Technologies, Inc.)</strong></p>
</blockquote>
<blockquote>
<p>Jenny Nelson received her Ph.D. in Analytical Chemistry from the University of Cincinnati in 2007, and her MBA from Saint Mary’s College of California in 2011. Currently, Jenny is an Application Chemist for the Life Science and Chemical Analysis team at Agilent Technologies, joining in 2012 (with a step away in 2019). Jenny is also an Adjunct Professor in the Department of Viticulture and Enology at University of California, Davis since 2013. Jenny has been very active with AOAC and ASTM over the past 8 years, serving on expert review panels, chairing committees, and volunteering to develop new methods needed by the industry.</p>
</blockquote>


Agilent Technologies: Alcoholic Beverages Virtual Seminar

Alcoholic Beverages Virtual Seminar - Wine

Characterizing free and bound monoterpene alcohols in wine fermentations & Solventless Extraction Techniques & Element Profiles and Arsenic Species.

<p><strong>Agilent and GERSTEL are happy to host this 4-day live virtual seminar discussing how you can assure safety, authenticity, and quality of alcoholic beverages. The focus will be on sharing the latest in technology developments and capabilities, new applications, and customer stories. Topics include spirits, wine, beer, and cider.  There is something for everyone in this seminar series and we are glad to see you here.</strong></p>
<h3><strong>Presentation 1: Identification of Markers of Consumer Acceptability in Lager Beer</strong></h3>
<ul>
<li><strong>Presenter: Benjamin Gelinas</strong> (Postdoctoral Researcher, Ohio State University)</li>
</ul>
<p>Beer remains the largest alcoholic beverage category in terms of volume of consumption, with lager beer being the largest style. An un-targeted flavoromics approach coupling consumer acceptability ratings of 15 lager beers was used to identify markers of consumer acceptability in beer. Top variables of importance were isolated, quantified, and identified prior to recombination studies to demonstrate the effect of these compounds on consumer acceptance and preference.</p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>Improved understanding of chemical drivers of beer on acceptance</li>
<li>Improved understanding of the role of iso-humulones on bitterness in beer</li>
<li>Implications of ingredients and processing on flavor and consumer acceptance</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>Personnel involved in the production of lager beer or lager beer ingredients</p>
<h3><strong>Presentation 2: LC-MS Analysis of Hop-Derived Humulone Constituents in Beer</strong></h3>
<ul>
<li><strong>Presenter: Prof. Bruce C. Hamper</strong> (Associate Teaching Professor, University of Missouri – St. Louis)</li>
</ul>
<p>Hops are essential ingredients for the brewing of beer, providing bitter flavors, desirable taste and hops aroma in the final product. The contribution of humulones and related components in hops to bitter flavors in beer is dependent on numerous factors including the quality, variety and quantity of hops used, specific addition protocols during the brewing recipe, nature of other ingredients and details of the brewing process.  Liquid chromatography-mass spectrometry (LC-MS) using electrospray ionization coupled with selective ion monitoring (SIM-MS) is particularly useful for profiling the compounds obtained from hops utilization during brewing.  Small scale brews from university brewing courses can be compared and evaluated in an efficient manner. </p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>Importance of LC-MS using selective ion monitoring for rapid analysis of complex samples.</li>
<li>Impact of key ingredients used in the brewing of beer on beer flavor.</li>
<li>Key features of hops components and their contribution to beer bitterness.</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>This webcast will be of interest to scientists using analytical techniques for measurement of multiple components in complex mixtures.  Focusing on food analysis provides intriguing examples that can relate to everyday experience and capture the imagination.  Science educators will be interested in the application of these techniques to classroom and laboratory exercises.</p>
<h3><strong>Presentation 3: A HS-SPME Arrow/GC-MS Method for Determination of Smoke Taint-Related Volatile Phenols in Humulus lupulus</strong></h3>
<ul>
<li><strong>Presenter: Stacey Williams</strong> (Senior Chemist, New Belgium Brewing Company)</li>
<li><strong>Presenter: Justin Alexander</strong> (Analytical Chemist, New Belgium Brewing Company)</li>
</ul>
<p>With a record-breaking fire season across the Western US, an unknown number of food crops were exposed to significant quantities of smoke. Due to the length of the season, Humulus lupulus (hops) were exposed to smoke prior to harvest and during processing. Guaiacol and 4-methylguaiacol (4MG) are routinely used as markers to determine the extent of smoke-taint in the wine industry. Quantitating these compounds in smoke-exposed hops prior to use in the brewing process is needed to predict the likelihood of perceptible smoke taint in finished beer. This presentation encompasses the validated analytical method to accurately quantitate unbound guaiacol and 4-methylguaiacol in smoke-exposed hops.</p>
<h5><strong>Key Learning Objectives/What attendees will learn:</strong></h5>
<ul>
<li>Potential challenges in the raw material supply chain for the brewing industry</li>
<li>Validation of an analytical method</li>
<li>The impact of high aroma active volatiles (i.e., phenols) to beer</li>
</ul>
<h5><strong>Who Should Attend:</strong></h5>
<p>Anyone interested in potential wildfire risks to food crops, especially those handling raw materials used in the brewing industry</p>
<blockquote>
<p><strong>Presenter: Benjamin Gelinas (Postdoctoral Researcher, Ohio State University)</strong></p>
</blockquote>
<blockquote>
<p>Ben Gelinas is a postdoctoral researcher at Ohio State University whose primary research focuses on Beer and Beer acceptability. Ben’s background is in analytical flavor chemistry working at the Flavor Research and Education Center at Ohio State University.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Prof. Bruce C. Hamper (Associate Teaching Professor, University of Missouri – St. Louis)</strong></p>
</blockquote>
<blockquote>
<p>Prof. Bruce Hamper teaches courses in brewing science and general chemistry at the University of Missouri-St. Louis. He leads a research group investigating synthesis and analysis of organic compounds and potential pharmaceutical agents. Current research includes development of synthetic methods for preparation of biomolecules using continuous flow processing. His group is also involved in development of analytical methods for profiling components in fermented beverages.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Stacey Williams (Senior Chemist, New Belgium Brewing Company)</strong></p>
</blockquote>
<blockquote>
<p>Stacey Williams earned a BS in Chemistry at Metropolitan State College in Denver. She has extensive experience in high performance liquid chromatography (HPLC), gas chromatography (GC) and mass spectrometry through her work in pharma, biopharma and the beer industry. She is currently a principal scientist at New Belgium in the QA lab with responsibilities including method development, validation, gas chromatography - olfactory (GC-O) and instrument troubleshooting.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Justin Alexander (Analytical Chemist, New Belgium Brewing Company)</strong></p>
</blockquote>
<blockquote>
<p>Justin Alexander graduated from Colorado State University with a Bachelor of Science in Fermentation Science &amp; Technology with a Minor in Food Science &amp; Safety. He has multiple years of experience in ultra-performance liquid chromatography (UPLC), primarily focusing on hop bittering components, organic acids, and fermentable carbohydrates. He currently holds a Scientist role in Quality Assurance at New Belgium Brewing Company in the Analytical Chemistry Lab.</p>
</blockquote>


Alcoholic Beverages Virtual Seminar - Beer

Markers of Consumer Acceptability in Lager Beer & LC-MS Hop-Derived Humulone Constituents in Beer & HS-SPME Arrow/GC-MS of Smoke Taint-Related Volatile Phenols.

<p><strong>Per- and polyfluoroalkyl substances (PFAS), an emerging class of toxic anthropogenic chemicals persistent in the environment, are currently regulated at the low part-per-trillion level worldwide in drinking water. Quantification and screening of these compounds currently rely primarily on liquid chromatography mass spectrometry (LC-MS).</strong></p>
<p>To better meet the regulatory demands of rapid screening of these chemicals, the hyphenating of solid phase microextraction (SPME) with direct analysis in real time (DART) will be demonstrated. PFAS analysis screened rapidly by DART on the Bruker EVOQ triple quadrupole using LC free workflows demonstrates a significant increase in productivity whilst also presenting a more economical and a greener solution for the lab.</p>
<p>Join us live for the real-time analysis of PFAS with SPME-DART-MS and discover the power of our cutting-edge instrumentation and technologies. </p>
<blockquote>
<p><strong>Presenter:</strong> William Fatigante (Applications Scientist, DART-MS at Bruker Applied Mass Spectrometry)</p>
</blockquote>


Bruker Applied Mass Spectrometry - Chromatography-Free Screening of PFAS Enabled Through SPME-DART-MS

Chromatography-Free Screening of PFAS Enabled Through SPME-DART-MS

Screening of PFAS Enabled Through SPME-DART-MS

<h4><strong>PFAS in Focus</strong></h4><p><strong>Welcome to the PFAS in Focus, a comprehensive and exclusive 10-parts webinar series sponsored by Shimadzu, covering the basics and beyond about the analysis of Per- and Polyfluoroalkyl Substances (PFAS) in the environment. In these five webinars, our experts will demonstrate the suitability of various analytical techniques, such as LCMS, GCMS, CIC, and QTOF, for PFAS testing.</strong></p><p>Join our experts, live or on-demand after the original air date, to demystify the challenges of PFAS analysis and <strong>gain the insights you need to</strong>:</p><ul><li>Manage PFAS contamination in your laboratory.</li><li>Master standardized methods for PFAS testing.</li><li>Discover new analytical workflows to maximize the performance of your instruments (LC-MS/MS, GCMS, CIC, QTOF) for PFAS analysis.</li></ul><h5><strong>Who should attend:</strong></h5><ul><li><strong>Environmental industry professionals</strong> and academics currently working on PFAS analysis or looking to establish the application in their labs.</li><li><strong>Representatives </strong>from drinking and wastewater utilities.</li><li><strong>LC–MS users </strong>from any field interested in expanding their applications to include PFAS testing.</li></ul><h4><strong>Part 02: Leveraging GC-MS and CIC as Complementary Techniques to LC-MS for a Comprehensive PFAS Solution</strong></h4><p><strong>The demand for per and polyfluoroalkyl substances (PFAS) analysis is growing. To date, there are several standardized PFAS methods. Most of these methods are based on Liquid Chromatography/Mass Spectrometry (LC/MS) techniques. However, LC/MS is not suitable to analyze all PFAS compounds because of the diverse physicochemical properties of chemicals within the PFAS family. Gas Chromatography/Mass Spectrometry GC/MS as a complementary technique can address volatile PFAS compounds that are challenging to be analyzed by LC/MS.&nbsp;</strong></p><p>In this webinar, a Head-Space Solid Phase Microextraction-Triple Quadrupole Gas Chromatography/Mass Spectrometry (HS-SPME GC/MS/MS) analytical method is used to analyze volatile PFAS in water. In addition, we will discuss Adsorbable Organic Fluoride (AOF) analysis by Combustion Ion Chromatography (CIC). This method provides information on the total amount of PFAS that may not be targeted by other selective chromatography methods.</p><p>We will host a Q&amp;A session after the presentation to address any questions or comments.</p><blockquote><p><strong>Presenter: </strong>Andy Sandy (GCMS Application Scientist, Shimadzu Scientific Instruments)</p><p>Andy Sandy is a Gas chromatography-Mass Spectrometry (GC-MS) Applications Scientist at Shimadzu Scientific Instruments, USA. In 2016, he joined the company. At Shimadzu he is a part of a dynamic application group, which is responsible for developing applications that provide solutions to complex analytical issues. Prior to working at Shimadzu, he completed a post-doctoral study at University of Illinois at Chicago, where he focused on developing environmental analytical methods for identifying and measuring emerging contaminant in the environment.</p><p><strong>Presenter:&nbsp;</strong>Andriy Savka (Shimadzu Scientific Instruments)</p><p>Andriy is an accomplished Product Specialist in the HPLC product group at Shimadzu Scientific Instruments, specializing in Ion Chromatography and other HPLC applications. He developed his chromatography expertise through roles in the pharmaceutical industry and Shimadzu's service team. In his current role within the HPLC group at headquarters, he works on various IC projects providing technical support for customers and developing IC applications for environmental, chemical, and other markets. He combines his technical and scientific background with his emerging business acumen to align product development with market needs, thereby enhancing customer satisfaction. Andriy holds a bachelor’s degree in chemistry from Saint Joseph's University and is currently pursuing an MBA at the University of Maryland Global Campus, with anticipated graduation in March 2025.</p><p><strong>Presenter:&nbsp;</strong>Alan Owens (GC &amp; GCMS Product Manager, Shimadzu Scientific Instruments)</p><p>Alan Owens is the GC and GCMS Product Manager at Shimadzu Scientific Instruments. Alan received his B.S. degree in Biology and Chemistry from Hampden-Sydney college. He then joined Shimadzu as a GCMS Product Specialist at the corporate headquarters in Columbia, MD. Before his time with Shimadzu, he comes from a flavor and fragrance background with expertise in advanced sample introduction techniques such as SPME and Dynamic headspace. He has since expanded into all sample introduction techniques specifically tailored towards Pyrolysis with a heavy influence of plastics and polymers.</p></blockquote>

Leveraging GC-MS and CIC as Complementary Techniques to LC-MS for a Comprehensive PFAS Solution

In this webinar, a HS-SPME GC/MS/MS analytical method is used to analyze volatile PFAS in water. 

GC-MS and CIC as Complementary Techniques to LC-MS for PFAS

<p><strong>There is increased concern regarding the authenticity of basmati rice throughout the world. For years, traders have been passing off a lesser quality rice as the world&#39;s finest long-grained, aromatic rice, basmati, in key markets like the US, Canada and the EU.</strong></p>
<p>In this on-demand webinar, we describe a proof of principle method to assess the authenticity of basmati rice using the latest advancements in high resolution GC-MS and informatics technologies. Volatile compounds of interest were extracted from heated dry rice via SPME and headspace. Following a generic GC separation, detection was performed using a SYNAPT G2-Si MS run in HDMSE mode. Collection of a HDMSE dataset offers a high level of specificity owing to the orthogonal nature of the ion mobility separation to the GC separation.</p>
<p>Progenesis QI, the latest OMICS informatics package from Waters, is designed to utilize the 4-dimensional data produced during a SYNAPT G2-Si HDMSE acquisition. Initially, alignment of all injections was performed followed by the unique peak co-detection process resulting in the same number of analyte measurements in every sample and no missing values. Data from all isotopes and adducts of a parent compound were then deconvoluted giving a single robust and accurate quantitative measurement for that parent compound. The peak picking and deconvolution algorithms ensure a high quality compound table where adducts and isotopes are grouped with the parent m/z. Compounds of interest from the rice samples were highlighted using various multivariate statistical techniques such as PCA and identified using elucidation tools and relevant database searches within the software platform.</p>
<p>This workflow has general applicability to many areas of discovery OMICS and food research where biomarkers differentiating between two or multiple groups are required.</p>
<h3><strong>What will I learn?</strong></h3>
<ul>
<li>An experimental workflow to evaluate the authenticity of foodstuffs</li>
<li>A basic workflow for the discovery of volatile biomarkers between multiple groups of samples</li>
<li>The basics of HDMSE data independent acquisition</li>
<li>How Progenesis QI is used to analyze metabolomics data</li>
</ul>
<h3><strong>Who should attend?</strong></h3>
<ul>
<li>Food research scientists</li>
<li>Metabolomics research scientists</li>
<li>Biomarker research scientists</li>
</ul>
<blockquote>
<p><strong>Presenter: Robert Tonge, Ph.D. (Senior Product Manager, OMICS Informatics, Waters Corporation)</strong></p>
</blockquote>
<blockquote>
<p>Dr Robert Tonge is Senior Product Manager for OMICS Informatics at Waters Corporation, Manchester UK. Robert has been at Waters for 4 years in both Product Development and Field Marketing and has approaching 20 years experience in OMICS science. He trained initially in Biochemistry and Toxicology before moving to &#39;Big Pharma&#39; where he worked in Discovery and Translational Research across a wide variety of disease areas from cancer, cardiovascular disease and infection research.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Gareth Cleland, Ph.D. (Principal Scientist, Food &amp; Environmental Business, Waters Corporation)</strong></p>
</blockquote>
<blockquote>
<p>Dr Gareth Cleland is a Principal Scientist within the Food and Environment Business Operations at Waters Headquarters, USA. Following his Chemistry studies, he started his professional career working as a Development Chemist for a small coatings company in Oxfordshire, UK. He joined Waters Corporation in 2002 and has held various roles within the organization, both UK and US based, over the last 12 years.</p>
</blockquote>


Pixabay/Trung Hieu Dang: Discovery OMICS and Progenesis QI for Food Authenticity Testing

Discovery OMICS and Progenesis QI for Food Authenticity Testing

<p><strong>Food samples that are fatty/oily, dried or highly complex matrices often pose challenges in the analytical process. Therefore, an efficient sample preparation providing a reliable removal or suppression of matrix components is the basis for accurate and reproducible results. In addition, the maintenance demand of the chromatographic systems should be reduced to a minimum.</strong></p>
<p>In this presentation, sample preparation tools based on zirconia-silica adsorbents for the QuEChERS methodology as well as in form of solid phase extraction (SPE) cartridges will be introduced. Their applicability and improved fat and pigment removal will be demonstrated for pesticide analysis in samples like avocado and spices, as well as for polycyclic aromatic hydrocarbons (PAHs) in edible oils. A special QuEChERS mix for green samples (e.g. for spinach) containing zirconia-coated material in combination with a specialized carbon adsorbent ensures sufficient chlorophyll removal while maintaining recovery for planar pesticides.</p>
<p>Furthermore, solid phase microextration (SPME), an easy-to-automate sample preparation technique, using overcoated (OC) adsorbent fibers will be discussed with application examples. These allow efficient adsorptive extraction of semi-volatile compounds from complex matrices like food samples by direct immersion.</p>
<h3><strong>Attend this presentation to learn about:</strong></h3>
<ul>
<li>the use and mechanisms behind zirconia-coated silica adsorbents</li>
<li>choosing a suitable material/tool for sample cleanup</li>
<li>how direct immersion SPME can be used for adsorptive extraction of less volatile compounds from complex food samples, expanding the applicability of SPME</li>
</ul>
<blockquote>
<p><strong>Presenter: Klaus Buckendahl (Analytical Sciences Liaison, Advanced Analytical Europe, Merck KGaA, Darmstadt, Germany)</strong></p>
</blockquote>
<blockquote>
<p>Klaus Buckendahl received a degree in engineering from the FH Münster University of Applied Science in Germany, majoring in instrumental analysis. He started his career in the technical service at Sigma-Aldrich providing support for the Supelco® line of analytical products. Over the last 20+ years, he held various positions within the company including Product Specialist and Technical Marketing Manager for Sample Preparation in Europe, among others. Currently he works as an Analytical Science Liaison at Merck in the analytical chemistry business unit.</p>
</blockquote>


Pixabay/Jill Wellington:  Sample Preparation for Fatty and Complex Food Matrices

LCMS webinars focusing on SPME - page 1