Agilent LC/MS Single Quadrupole Detectors in LabRulez Bazaar

Liquid Chromatography coupled with Mass Spectrometry (LC/MS) is an essential tool for sensitive, selective analysis of non-volatile and thermally labile compounds. The single quadrupole (SQ) detector is the most widely used LC/MS configuration, balancing robust performance with cost efficiency.

What is a Single Quadrupole LC/MS?

The quadrupole mass analyzer employs four parallel rods with oscillating electric fields to filter ions by mass-to-charge ratio (m/z). This allows analysts to detect specific compounds with high selectivity and sensitivity in complex mixtures.

Main Components

• Ion Source – typically electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI)
• Quadrupole Mass Filter – the core analytical element filtering ions by m/z
• Detector – electron multiplier converting ions into measurable signals
• Vacuum System – pumps maintaining high-vacuum conditions
• Electronics & Software – controlling acquisition, polarity switching, and data processing

Advantages

• Robust, reliable design – built for routine labs
• High sensitivity – trace analysis across many sample types
• Fast polarity switching – measure positive and negative ions in one run
• Broad applicability – pharma, environmental, food, chemical industries
• Cost-effective – lower investment and maintenance than MS/MS or HRMS

Applications

• Drug purity and QC testing
• Food safety (residues, contaminants, additives)
• Environmental monitoring (pesticides, pollutants)
• Chemical analysis in research labs

Available SQ LC/MS bazaar products:

1. Agilent 6140 Quadrupole LC/MS System (Refurbished)

High-performance LC/MS for precise, reliable and sensitive mass analysis. Part of the 6100 Series, suitable for both routine and complex tasks.

• Price: on request
• Detailed offer can be found here

2. Agilent 6120 Series (G6120B) LC/MSD (Refurbished)

Compact, robust, and ideal for routine applications. Features fast polarity switching and integration with OpenLab software.

• Price: on request
• Detailed offer can be found here

3. Agilent 6130 Series (G6130B) LC/MSD (Refurbished)

Flexible, precise single quadrupole LC/MS with excellent sensitivity and rapid data acquisition, supporting both routine and advanced analyses.

• Price: on request
• Detailed offer can be found here