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Keep Your LC Systems Performing: Essential Spare Parts for HPLC

Tu, 19.8.2025
| Original article from: LabRulezLCMS Bazaar
Find essential HPLC spare parts including pumps, valves, thermostats, and detectors. Keep your LC systems running smoothly with reliable Agilent replacements.
<p><strong>LabRulez:</strong> Keep Your LC Systems Performing: Essential Spare Parts for HPLC</p>

LabRulez: Keep Your LC Systems Performing: Essential Spare Parts for HPLC

High-performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) are indispensable techniques across pharmaceuticals, biochemistry, food safety, and environmental testing. An LC system consists of pumps, autosamplers, columns, detectors, and thermostats – each designed to deliver precise flow rates, reproducible injections, and stable detection.

Like all precision instruments, HPLC systems face wear and tear. Mechanical stress, high pressure, solvent exposure, and continuous operation gradually degrade critical parts.

Which Parts Break Down Most Often and Why?

  • Pumps and valves: Solvent contact and pressure cycling cause seals, pistons, and valves to wear over time, leading to leaks or unstable flow.
  • Autosamplers: Moving parts such as syringe motors, turret motors, and thermostats can fail after thousands of injection cycles.
  • Detectors (UV, RID, FLD): Optical units, lamps, and flow cells degrade with time and exposure, reducing sensitivity and stability.
  • Electronics and boards: Mainboards, flow sensors, and temperature controllers ensure precise operation, but age-related failures may occur.

What Needs to Be Replaced Frequently?

  • Pump seals, pistons, frits, and valves – regular maintenance items due to solvent and pressure stress.
  • Autosampler consumables such as syringe assemblies, motor belts, and needles.
  • Detector lamps, cells, and optical units to maintain sensitivity.
  • Electronics modules when errors or instability appear in the system.

Routine replacement of these parts reduces downtime, improves system stability, and ensures high-quality chromatographic data.

Offered HPLC Spare Parts

1. Agilent: Spare Parts Kit for LC Pumps, R007101667 (New)

Complete spare parts kit (R007101667) designed for LC systems, supporting a maximum flow rate of 10 mL.

2. Agilent: HPLC/UHPLC Vacuum Pump, G1311-60007 (Refurbished)

Vacuum pump for HPLC/UHPLC systems; ensures efficient solvent degassing for stable baselines and reliable chromatography.

3. Agilent: Gradient Valve Assembly for 1100 HPLC, G1311-67701 (Refurbished)

Gradient valve for Agilent 1100 HPLC; provides accurate solvent mixing and consistent delivery in gradient applications.

4. Agilent: Optical Unit Assembly, RID Infinity II, G7162-60001 (Tested)

Factory-aligned optical unit for Agilent G7162 RID. Ensures stable and accurate RI detection in InfinityLab LC systems.

5. Agilent: Mainboard for Autosampler, G7167-65850 (Tested)

Mainboard (G7167-65850), central control board for Agilent 1260 Infinity II Multisampler.

Agilent: Mainboard for Autosampler, G7167-65850Agilent: Mainboard for Autosampler, G7167-65850

6. Agilent: Optical Unit for HPLC RI Detectors, G1362-60002 (Tested)

Micro optical unit for Agilent 1260 Infinity III RID; 2.5 µL cell, LED light, up to 148 Hz, temp control to 55 °C, built-in diagnostics.

7. Agilent: Capillary Puller Tool (40 mm), G1964-60345 (Tested)

Specialized tool for safe and precise extraction or installation of 40 mm capillaries in Agilent LC/MS instruments.

8. Agilent: Flow Sensor 100 µL, G1376-60002 (New)

Precision flow sensor enabling capillary LC pumps to operate at up to 100 µL/min.

9. Agilent: Sample Thermostat, G7167-60101 (Refurbished)

Repair part for Agilent InfinityLab Sample Thermostat; ensures precise vial temperature control in LC systems.

Agilent: Sample Thermostat, G7167-60101Agilent: Sample Thermostat, G7167-60101

10. Agilent: Infinity II Sample Thermostat, G7167-60201 (Refurbished)

Dedicated thermostat for 1260/1290 Infinity II Multisamplers; maintains vial and plate thermal stability before injection.

11. Agilent: Infinity II Sample Thermostat, G7167-60201 (Repair Part)
Replacement module for 1260/1290 Infinity II Multisamplers; ensures optimal sample integrity via thermal stability of vials/plates.

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