<p><strong>Multiscale materials are assembled from different types of nanomaterials, which themselves have unusual properties. By combining and integrating them into higher-order hierarchies, smart matter with unique functionalities and surprising applications in many different fields can be obtained. A consortium of eight partners from academia and research, led by the J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, has received financial support from the Programme Johannes Amos Comenius of the Ministry of Education, Youth and Sports in the amount of CZK 480 million for research with this focus. Specifically, it was the Excellent Research Call aimed at supporting research with the potential for excellent results applicable in practice.</strong></p>
<p>The development of advanced materials with the required parameters and their integration into functional structures while maintaining their maximum utility value is the common denominator of modern materials research. Current directions in materials science draw inspiration from nature, where beyond naturally occurring elements and compounds, nature enables so-called material genetics, i.e. the targeted folding and &quot;cross-breeding&quot; of material components in 3D space.</p>
<p>Scientists are combining zero-dimensional (quantum dots), one-dimensional (e.g. nanotubes), and two-dimensional (e.g. graphene) materials in the lab to give them new and unusual properties. The challenge is to develop advanced, so-called multiscale materials with a wide range of applications, e.g. in electrical engineering, medicine, or environmental technologies.</p>
<p>Eight partners cooperate in the AMULET (Advanced MUltiscaLe materials for key Enabling Technologies) project. The coordinator is the <a href="https://www.jh-inst.cas.cz/"><strong>J. Heyrovsky Institute of Physical Chemistry of the CAS</strong></a>. Other members of the consortium involve the Institute of <a href="https://lcms.labrulez.com/companies/62"><strong>Organic Chemistry and Biochemistry of the CAS</strong></a> (PI: <a href="https://cigler.group.uochb.cz/cs"><strong>Dr. Petr Cígler</strong></a>), the Faculty of Science of Jan Evangelista Purkyně University in Ústí nad Labem, the Institute of Photonics and Electronics of the CAS, the Institute of Physics of the CAS, the Faculty of Mathematics and Physics and the Faculty of Science of Charles University, the Nuclear Physics Institute of the CAS and the <a href="https://lcms.labrulez.com/companies/11"><strong>University of Chemistry and Technology in Prague</strong></a>.</p>
<p>Linking the above institutions aims to promote the widest possible use of the anticipated newly developed unique materials. Experts will investigate how multiscale materials interact with the biological environment, whether they can be used for electrochemical or optical sensors, in electro-photochemical catalysis for the removal of pollutants from air and water, and last but not least, they will test new nano/micro-devices that can be used for energy conversion, production, and storage.</p>
<p>The AMULET project succeeded in the competition of 66 projects submitted to the Excellent Research call in the Programme Johannes Amos Comenius. This call is aimed at supporting research with the potential for excellent results applicable in practice. In total, 26 projects were supported for a total value of CZK 12.2 billion. The money is earmarked for excellent research teams, which will help Czech scientific institutions deepen their relations with foreign partners and strengthen the Czech Republic&#39;s competitiveness in the long run.</p>


Material genetics will be pursued by the AMULET project, which succeeded in the Excellent Research Call

<h3><strong>Chiral ION-QN &amp; Chiral ION-QD</strong></h3><p><i>Weak Anion-Exchanger (WAX) stationary phases for reliable chiral separation of acidic compounds</i></p><h4><strong>Transform Your Chiral Analysis</strong></h4><p>One of the main challenges of today’s liquid chromatography is chiral separation of ionised and ionisable analytes, e.g., organic acids, amino acids, N-protected amino acids, amino acid mimics, etc. The most efficient approach to purify and resolve such troublesome racemates utilises ion exchange-type stationary phases that facilitate strong interactions between the chiral selector and the analyte.</p><p>Galochrom introduces its own generic series of weak anion-exchangers, based on <i>tert</i>-butyl-carbamoylated Cinchona alkaloids quinine (QN) and quinidine (QD). These chiral phases have demonstrated excellent selectivity and improved peak resolution, resulting in highly accurate and replicable analyses. Our innovative manufacturing and strict quality control ensure that these generic columns not only outperform commercial alternatives, but also meet your technical requirements.</p><blockquote><p><span style="font-size:20px;"><strong>Chiral ION-QN &amp; Chiral ION-QD represent the most efficient approach to purify and resolve even the most challenging mixtures.</strong></span></p></blockquote><h4><strong>Applications</strong></h4><p>Chiral ION-QN &amp; Chiral ION-QD are ideal for enantioseparations of:</p><ul><li><strong>N-protected amino acids</strong></li><li><strong>Aminophosphonic &amp; Aminosulfonic acids</strong></li><li><strong>Lactic &amp; Thiolactic acids</strong></li><li><strong>Clenbuterol &amp; Thyroxin</strong></li></ul><h4><strong>Upgrade your separation performance and gain:</strong></h4><ul><li><strong>Premium enantioselectivity</strong></li><li>Elegant <strong>switch of the elution order of enantiomers</strong></li><li><strong>High-stability</strong> against all common HPLC solvents</li><li><strong>Seamless method transfer</strong></li></ul><h3><strong>Powerful Selectivity</strong></h3><p><i>Aim for the best resolution and selectivity possible</i></p><p>In collaboration with dozens of researchers, we have selected the best-performing derivatives of both quinine (QN) and quinidine (QD). As a result, the Chiral ION-QN features O-9-(tert-butylcarbamoyl)quinine, which is immobilized on fully-porous spherical silica (see below). The unique chiral scaffold of the cinchona backbone provides exceptional selectivity for wide array of acidic compounds.</p><p>The Chiral ION-QD features structurally similar selector to Chiral ION-QN. As a result, these selectors, while being diastereomers, act as pseudo-enantiomers. <strong>This feature enables elegant switch of elution order of enantiomers, which is often challenging for other chiral stationary phases.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_3_18e49ab8ee.jpg" alt="Galochrom: Chiral ION-QN &amp; Chiral ION-QD HPLC columns - Transform Your Chiral Analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_3_18e49ab8ee.jpg 241w," sizes="100vw" width="1908" height="1238"></p><h4><strong>Molecular recognition</strong></h4><p>The prime driving force for specific molecular association are electrostatic or ionic interactions. Once analyte reaches close proximity of the selector, weaker non-bonding interactions such as H-bonding, <span class="symbol">π</span>−<span class="symbol">π</span> stacking and steric interactions apply. These directive interactions result in different column retention per each enantiomer.</p><p><strong>Since analytes differ in combination and strength of these binding increments, our chiral stationary phase delivers superior molecular recognition.</strong></p><h4><strong>Supporting professionals across many industries</strong></h4><ul><li>Forensic Science</li><li>Chemical Manufacturing</li><li>Biotechnology</li><li>Agriculture</li><li>Academic Research&nbsp;</li><li>Pharmaceuticals</li><li>Food &amp; Quality Control</li></ul><h3><strong>Popular chiral columns</strong></h3><p><i>Essential tools with a wide range of applications</i></p><h4><strong>Find your best match</strong></h4><p>There are hundreds of chiral stationary phases available on the market. The selection of chiral HPLC columns below represents the most popular and top-performing choices for analysis and resolution of chiral acidic compounds. Displayed data are relevant to analytical and semi-preparative scale</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_4_5d48236baa.jpg" alt="Galochrom: Chiral ION-QN &amp; Chiral ION-QD HPLC columns - Transform Your Chiral Analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_4_5d48236baa.jpg 224w," sizes="100vw" width="1508" height="1052"></p><h4><strong>Take Full Advantage Of Unique Selectivity And Expand Your Research Possibilities</strong></h4><p>Chiral ION-QN &amp; Chiral ION-QD now available at <strong>ANALYTICAL &amp; PREPARATIVE</strong> scale</p><h3><strong>Order information</strong></h3><h4><strong>Analytical Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION01-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION02-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><p><span style="font-size:12px;">*As an alternative, we can also offer 150x3 mm, 3 μm with 120 Å</span></p><h4><strong>Preparative Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION03-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION04-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION05-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION06-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><blockquote><h3><strong>SPECIAL OFFER 1+1</strong></h3><p><span style="font-size:22px;"><strong>Buy 1 preparative column and get analytical column for FREE</strong></span></p><p>You can choose 150x4 or 250x4 column with the same sorbent as your preparative column.</p></blockquote>

Chiral ION-QN & Chiral ION-QD HPLC columns - Transform Your Chiral Analysis

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The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Galochrom is a chromatography pioneer, providing custom solutions for HPLC separations, compound purification and method development.

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