MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part I will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction of Presenter, James Little</li>
<li>Table of Contents </li>
<li>Series Topics</li>
<li>NIST MS Software and MSMS (Tandem) Libraries</li>
<li>Help Files for NIST Search</li>
<li>NIST Software Windows Compliant Features</li>
<li>Saving and Restoring User Configurations</li>
<li>Main Functions on Toolbar</li>
<li>View of Search Options Employed</li>
<li>Main Window in Lib Search View</li>
<li>Tabs for Other Functions Accessed at Bottom of Main Library Window</li>
<li>Names Search Tab </li>
<li>Setting Up search Parameters for MSMS Searches</li>
<li>InChiKey Field Link to PubChem on Web </li>
<li>Molecular Formulae for Fragments Shown in High Resolution Spectra</li>
<li>Live Demo on YouTube of Software </li>
<li>References (Internet Links)</li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part II: NIST MSMS Search Software and Libraries</li>
<li>Part III: More Detailed Discussion of MSMS Hybrid Search</li>
<li>Part IV: Importing MSMS Spectra</li>
<li>Part V: NIST Structure Searches</li>
<li>Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</li>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part I: Overview of Software and User-Customized Configurations

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part II will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction to Presenter, James Little</li>
<li>Table of Contents </li>
<li>Series of Talks: LCMS Unknown Identifications Using MSMS Libraries</li>
<li>Help Files for NIST Search</li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>NIST Tandem Quick Start Guide</li>
<li>Overview: NIST Mass Spectrometry Software and MSMS Libraries </li>
<li>Limitations of MSMS Searches for Unknown Identifications </li>
<li>Three Basic Types of NIST MSMS (Tandem) Searches </li>
<li>Overall Description for Searching Libraries and Displaying Results</li>
<li>NIST MSMS (Tandem) Libraries 2020 Release </li>
<li>Minimizing Number of Results After Search Performed </li>
<li>Two Types of Ions Filtered with MSMS Hit List Filter Option </li>
<li>Setting Default Parameters for Similarity Search (7 Steps)</li>
<li>Setting Default Parameters for Identify MS/MS Search (8 Steps) </li>
<li>Setting Default Parameters for MS/MS Hybrid Search (9 Steps) </li>
<li>Searching Demonstration (Live YouTube) </li>
<li>Presentation References (Internet Hyperlinks)</li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part III: More Detailed Discussion of MSMS Hybrid Search</li>
<li>Part IV: Importing MSMS Spectra</li>
<li>Part V: NIST Structure Searches</li>
<li>Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</li>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part II: NIST Search Software and Libraries

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part III will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction to Presenter, James Little</li>
<li>Table of Contents</li>
<li>Series of Talks: LCMS Unknown Identifications Using MSMS Libraries</li>
<li>Help Files for NIST Search</li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>Presentation Topics</li>
<li>Program Description and My Personal Experience</li>
<li>Comparison to Standard versus Neutral Loss Spectrum</li>
<li>Hybrid Search Results for Example</li>
<li>Using DotProduct Instead of Score for Viewing Results</li>
<li>DeltaMass Table</li>
<li>Simple Examples Using Structures to Show DeltaMass</li>
<li>Viewing Peak Matching Results by Sorting in Hybrid Search Results</li>
<li>Merging Hybrid with Peak Matching Results</li>
<li>Detailed Explanation of Hybrid Head to Tail Display</li>
<li>Alternate Neutral Loss Comparison in Head to Tail Format</li>
<li>Other Things to Consider with Hybrid Search for Unknown Identification</li>
<li>Setting Up CriticalDefault Parameters for MS/MS Hybrid Search</li>
<li>Live Searching Demonstration YouTube Video</li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part IV: Importing MSMS Spectra</li>
<li>Part V: NIST Structure Searches</li>
<li>Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</li>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part III: More Detailed Discussion of MSMS Hybrid Search

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part IV will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction of Presenter, James Little</li>
<li>Table of Contents </li>
<li>Series Topics</li>
<li>Help Files for NIST Search</li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>Abbreviations Used in Text and Useful Keyboard Sequences </li>
<li>Methods for ImportingSpectra Directlyin MSP Format to NIST</li>
<li>Mass Spec Manufactures Current Use of NIST Search</li>
<li>Example of Capability Utilized by Agilent</li>
<li>Example of Imported Agilent Spectrum</li>
<li>Example of Mult-Spectra Import of Agilent Spectra </li>
<li>Importance of Proper Settings in NIST Spectrum Import Options</li>
<li>Importing Spectra Manually Indirectlyin MSP and Other Formats </li>
<li>Exporting Spectra Manually in MSP and Other Formats </li>
<li>Example of Typical NIST Entry in *.MSP Format</li>
<li>Live YouTube Demonstration </li>
<li>References with Internet Links </li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part V: NIST Structure Searches</li>
<li>Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</li>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part IV: Importing MSMS Spectra

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part V will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction of Presenter, James Little </li>
<li>Table of Contents</li>
<li>Series Topics</li>
</ul>
-Help Files for NIST Search 
<ul>
<li>NIST Software in General is “Windows Compliant”</li>
<li>Session Topics and Choice of Drawing Program</li>
<li>Critical Settings for Similar Structure Searches</li>
<li>Critical Settings for Exact Structure Searches </li>
<li>Critical Settings Turn Off Any Filtering Options Initially</li>
<li>Obtaining Structure from Drawing Program </li>
<li>Pasting Structure into NIST Search </li>
<li>Search for Similar Structures after Inserting Clipboard Structure </li>
<li>Search for Exact Structures </li>
<li>Tips for Displaying Similar and Exact Search Result with DeltaMass </li>
<li>Reverse Process: Sending Structures from NIST to Drawing Program </li>
<li>Using Compare Window to Display Multiple Spectra </li>
<li>Sending Structures Directly to Drawing Program</li>
<li>Live Demo YouTube Presentation</li>
<li>Presentation References (Internet Links)</li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</li>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>
<h3>The past sections have focused on:</h3>
<ul>
<li><a href="https://lcms.labrulez.com/article/1068">Part I: Overview of Software and User-Customized Configurations</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1088">Part II: NIST Search Software and Libraries</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1110">Part III: More Detailed Discussion of MSMS Hybrid Search</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1130">Part IV: Importing MSMS Spectra</a>
</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part V: NIST Structure Searches

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part VI will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction of Presenter, James Little</li>
<li>Table of Contents</li>
<li>Series Topics</li>
<li>Help Files for NIST Search </li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>Session Topics </li>
<li>Adding a Structure to a Spectrum</li>
<li>Sending Spectrum with Structure to MS Interpereter </li>
<li>Processing Data in MS Interpreter </li>
<li>Suggested Default Settings</li>
<li>Displaying the Propose Substructures Correlated to Ions </li>
<li>Stepping through More Than One Proposed Structure </li>
<li>Lassoing Structures Manually </li>
<li>Processing Any Entry in NIST Search with structure/spectrum</li>
<li>Direct Structure Paste in MS Interpreter </li>
<li>Processing MS/MS Spectra Containing Isotopic Clusters</li>
<li>Live YouTube Demonstration</li>
<li>References with Internet Links</li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part VII: Using and Creating Other MSMS Libraries</li>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>
<h3>The past sections have focused on:</h3>
<ul>
<li><a href="https://lcms.labrulez.com/article/1068">Part I: Overview of Software and User-Customized Configurations</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1088">Part II: NIST Search Software and Libraries</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1110">Part III: More Detailed Discussion of MSMS Hybrid Search</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1130">Part IV: Importing MSMS Spectra</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1162">Part V: NIST Structure Searches</a>
</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part VI: MS Interpreter Correlation of Substructure to MSMS Ions

Liquid chromatography and gas chromatography coupled with mass spectrometry (LC/MS, GC/MS) are two major analytical techniques for identifying compounds in complex mixtures. This symposium provides a forum for experts from industry, academia and government agencies to share their novel experimental methods, creative data analysis techniques including mass spectral library searching and software development, and the applications of these techniques, with special emphasis on the use of LC/MS/MS in metabolomics, proteomics, lipidomics, forensics, pharmaceutical and environmental studies.
<h3>Abstract</h3>
For the last 20 years, Eastman has routinely employed the NIST search for the identification of unknowns. Initially, we primarily utilized EI searches, but in recent years, the increase in the availability and quality of tandem libraries plus associated software has greatly enhanced LC-MS library search results. More than 50 instruments and associated users are networked at Eastman world-wide. Our corporate library of &gt;55K entries in NIST format is automatically updated and distributed nightly.
The 2020 edition of the NIST library utilized with the NIST MS 2.4 search software offers many major enhancements. NIST for the last six years has had an ambitious program to acquire and analyze targeted chemicals (&gt;50,000). In addition, the novel <a href="https://gcms.labrulez.com/article/1128">hybrid GCMS EI and MSMS search</a> and <a href="https://lcms.labrulez.com/article/1110">LC/MS/MS Hybrid Search</a> expands the scope of all EI and tandem libraries.
PDF Presentation <a href="https://gcms.labrulez.com/paper/13187">for download</a>.
<h3>Detailed lectures from the series using the new version of NIST in GCMS and LCMSMS:</h3>
<ul>
<li><a href="https://gcms.labrulez.com/articles?search=nist&amp;tags=34">James Little - Wiley GCMS Seminar</a> at LabRulezGCMS
</li>
<li><a href="https://lcms.labrulez.com/articles?search=nist&amp;tags=34">James Little - LC/MS Unknown Identifications Using MSMS Libraries Seminar</a> at LabRulezLCMS
</li>
</ul>

Identification of Unknowns by GC-MS and LC-MS Using NIST Search with Commercial and User Libraries

MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release. 
I will attempt to introduce the user to the use of the NIST Version 2.4 search software employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the identification of unknowns.
NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. 
See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a>
This involves a very comprehensive process for selecting pertinent compounds for purchase and subsequent analyses. The problem with variability of the spectra is reduced by analyzing the samples on a variety of instruments at a variety of energy levels (20 steps). In addition, many different precursor ions and fragment ions are characterized (MSⁿ). This has already led to a very large high quality library of accurate mass MS/MS spectra in the 2020 release version (31K compounds/1.3 M spectra) and the effort is ongoing.
<h3>The Part VII will cover:</h3>
Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.
<ul>
<li>Introduction to Presenter, James Little</li>
<li>Table of Contents </li>
<li>Series of Talks: LCMS Unknown Identifications Using MSMS Libraries</li>
<li>Read This Before Utilizing Handout </li>
<li>Philosophy on Incorporating User and Commercial Libraries in Identifications</li>
<li>User Libraries Converted and Approach </li>
<li>NIST Lib2NIST Utility for Library Conversions</li>
<li>Accessing Lib2NIST Utility </li>
<li>Quality of MoNA and Converting to NIST format</li>
<li>Low Resolution (lr_) versus High Resolution MSMS NIST Libraries</li>
<li>Problems Converting and Searching User Libraries and “Work-Arounds” </li>
<li>Composition of the MoNA Libraries and Structures in MoNA GCMS Library</li>
<li>Conversion of Wiley Commercial Libraries with Lib2NIST </li>
<li>Conversion of Personal User Library with no Precursor_m/z field </li>
<li>PowerShell Script for Adding Precursor_m/z to Personal User Library</li>
<li>Creating/Adding User Library within NIST Search Program </li>
<li>What If My Imported Library Spectrum Contained No Precursor_m/z Field?</li>
<li>What IF I Need to Add Several Different Fields for a Set of Spectra? </li>
<li>“Re(Index)” Library Indices After Additions or Creating New Library </li>
<li>Automatic Distribution of Eastman Libraries Over Network</li>
<li>Live Demo on YouTubeWebinar References (Internet Links) </li>
<li>Acknowledgements</li>
</ul>
<h3>Future parts will focus on:</h3>
<ul>
<li>Part VIII: Identification of Unknowns with “Spectraless” Libraries</li>
</ul>
<h3>The past sections have focused on:</h3>
<ul>
<li><a href="https://lcms.labrulez.com/article/1068">Part I: Overview of Software and User-Customized Configurations</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1088">Part II: NIST Search Software and Libraries</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1110">Part III: More Detailed Discussion of MSMS Hybrid Search</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1130">Part IV: Importing MSMS Spectra</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1162">Part V: NIST Structure Searches</a>
</li>
<li><a href="https://lcms.labrulez.com/article/1221">Part VI: MS Interpreter Correlation of Substructure to MSMS Ions</a>
</li>
</ul>

LC/MS Unknown Identifications Using MSMS Libraries Part VII: Using and Creating Other MSMS Libraries

Article

Product

Events

Webinars

Application

Academy

Video

Poster

Scientists

Plastics

Environment

Food

Water

Health

Presentation

Scientific article

Interview

Toxicology

Popularization

Science and research

Software

Covid-19

Career

Laboratories

Various

Zaměření

Type of News

Focus

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Introduction to HPLC

GPC & SEC Training 2026

Thermo Fisher Scientific at CFSRE 2026

Transform Your Daily Lab Operations with Automation - Proteomics Workflows

Keeping Up with Evolving Regulatory Requirements: Addressing Analytical Challenges for Known and Unknown Nitrosamines

Assessing biotherapeutic stability through forced degradation using intact and subunit icIEF-UV/MS workflows