<h3><strong>Chiral ION-QN &amp; Chiral ION-QD</strong></h3><p><i>Weak Anion-Exchanger (WAX) stationary phases for reliable chiral separation of acidic compounds</i></p><h4><strong>Transform Your Chiral Analysis</strong></h4><p>One of the main challenges of today’s liquid chromatography is chiral separation of ionised and ionisable analytes, e.g., organic acids, amino acids, N-protected amino acids, amino acid mimics, etc. The most efficient approach to purify and resolve such troublesome racemates utilises ion exchange-type stationary phases that facilitate strong interactions between the chiral selector and the analyte.</p><p>Galochrom introduces its own generic series of weak anion-exchangers, based on <i>tert</i>-butyl-carbamoylated Cinchona alkaloids quinine (QN) and quinidine (QD). These chiral phases have demonstrated excellent selectivity and improved peak resolution, resulting in highly accurate and replicable analyses. Our innovative manufacturing and strict quality control ensure that these generic columns not only outperform commercial alternatives, but also meet your technical requirements.</p><blockquote><p><span style="font-size:20px;"><strong>Chiral ION-QN &amp; Chiral ION-QD represent the most efficient approach to purify and resolve even the most challenging mixtures.</strong></span></p></blockquote><h4><strong>Applications</strong></h4><p>Chiral ION-QN &amp; Chiral ION-QD are ideal for enantioseparations of:</p><ul><li><strong>N-protected amino acids</strong></li><li><strong>Aminophosphonic &amp; Aminosulfonic acids</strong></li><li><strong>Lactic &amp; Thiolactic acids</strong></li><li><strong>Clenbuterol &amp; Thyroxin</strong></li></ul><h4><strong>Upgrade your separation performance and gain:</strong></h4><ul><li><strong>Premium enantioselectivity</strong></li><li>Elegant <strong>switch of the elution order of enantiomers</strong></li><li><strong>High-stability</strong> against all common HPLC solvents</li><li><strong>Seamless method transfer</strong></li></ul><h3><strong>Powerful Selectivity</strong></h3><p><i>Aim for the best resolution and selectivity possible</i></p><p>In collaboration with dozens of researchers, we have selected the best-performing derivatives of both quinine (QN) and quinidine (QD). As a result, the Chiral ION-QN features O-9-(tert-butylcarbamoyl)quinine, which is immobilized on fully-porous spherical silica (see below). The unique chiral scaffold of the cinchona backbone provides exceptional selectivity for wide array of acidic compounds.</p><p>The Chiral ION-QD features structurally similar selector to Chiral ION-QN. As a result, these selectors, while being diastereomers, act as pseudo-enantiomers. <strong>This feature enables elegant switch of elution order of enantiomers, which is often challenging for other chiral stationary phases.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_3_18e49ab8ee.jpg" alt="Galochrom: Chiral ION-QN &amp; Chiral ION-QD HPLC columns - Transform Your Chiral Analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_3_18e49ab8ee.jpg 241w," sizes="100vw" width="1908" height="1238"></p><h4><strong>Molecular recognition</strong></h4><p>The prime driving force for specific molecular association are electrostatic or ionic interactions. Once analyte reaches close proximity of the selector, weaker non-bonding interactions such as H-bonding, <span class="symbol">π</span>−<span class="symbol">π</span> stacking and steric interactions apply. These directive interactions result in different column retention per each enantiomer.</p><p><strong>Since analytes differ in combination and strength of these binding increments, our chiral stationary phase delivers superior molecular recognition.</strong></p><h4><strong>Supporting professionals across many industries</strong></h4><ul><li>Forensic Science</li><li>Chemical Manufacturing</li><li>Biotechnology</li><li>Agriculture</li><li>Academic Research&nbsp;</li><li>Pharmaceuticals</li><li>Food &amp; Quality Control</li></ul><h3><strong>Popular chiral columns</strong></h3><p><i>Essential tools with a wide range of applications</i></p><h4><strong>Find your best match</strong></h4><p>There are hundreds of chiral stationary phases available on the market. The selection of chiral HPLC columns below represents the most popular and top-performing choices for analysis and resolution of chiral acidic compounds. Displayed data are relevant to analytical and semi-preparative scale</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_4_5d48236baa.jpg" alt="Galochrom: Chiral ION-QN &amp; Chiral ION-QD HPLC columns - Transform Your Chiral Analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Chiral_ION_QN_and_Chiral_ION_QD_HPLC_columns_Transform_Your_Chiral_Analysis_4_5d48236baa.jpg 224w," sizes="100vw" width="1508" height="1052"></p><h4><strong>Take Full Advantage Of Unique Selectivity And Expand Your Research Possibilities</strong></h4><p>Chiral ION-QN &amp; Chiral ION-QD now available at <strong>ANALYTICAL &amp; PREPARATIVE</strong> scale</p><h3><strong>Order information</strong></h3><h4><strong>Analytical Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION01-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION02-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><p><span style="font-size:12px;">*As an alternative, we can also offer 150x3 mm, 3 μm with 120 Å</span></p><h4><strong>Preparative Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION03-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION04-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION05-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION06-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><blockquote><h3><strong>SPECIAL OFFER 1+1</strong></h3><p><span style="font-size:22px;"><strong>Buy 1 preparative column and get analytical column for FREE</strong></span></p><p>You can choose 150x4 or 250x4 column with the same sorbent as your preparative column.</p></blockquote>

Chiral ION-QN & Chiral ION-QD HPLC columns - Transform Your Chiral Analysis

<h3><strong>Method Development</strong></h3><p><i>Develop robust methods that are easily transferable across laboratories</i></p><h4><strong>Engineered for reliable method development</strong></h4><p>Successful methods rely on results that can tolerate minor variations in chromatographic parameters. It is very important<br>to have proper tools to easily and quickly develop robust methods. Chiral ION-QN and Chiral ION-QD are designed to<br>provide you with accurate and consistent results, that are transferable across different LC system platforms. You can<br>rapidly develop methods in several chromatographic modes:</p><ul><li><strong>Normal-phase</strong></li><li><strong>Reversed-phase</strong></li><li><strong>Polar organic</strong></li><li><strong>SFC</strong></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1241"><strong>Chiral ION-QN</strong></a><strong> &amp; </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1240"><strong>Chiral ION-QD</strong></a></h4><ul><li><strong>Consistent performance:</strong> Make your results easily transferable</li><li><strong>Remarkable selectivity:</strong> Easily separate closely eluting peaks</li><li><strong>Ideal for method development:</strong> Reduce your time and costs spent</li></ul><h4><strong>How can Galochrom columns enhance your methods?</strong></h4><ul><li><strong>Consistent reproducibility: </strong>Eliminate process variance and achieve your results with confidence</li><li><strong>Seamless method scale-up: </strong>Transform your analytical method into preparative purification</li><li><strong>Save time and money: </strong>Spend more time on efficient separations and less time on troubleshooting</li><li><strong>Better peak shapes: </strong>Easily resolve even the most challenging mixtures</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Method_Development_and_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_Consistent_reproducibility_Seamless_method_scale_up_Save_time_and_money_Better_peak_shapes_4b220cd029.jpg" alt="Galochrom: Consistent reproducibility, Seamless method scale-up, Save time and money, Better peak shapes." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Method_Development_and_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_Consistent_reproducibility_Seamless_method_scale_up_Save_time_and_money_Better_peak_shapes_4b220cd029.jpg 245w," sizes="100vw" width="921" height="175"></p><h3><strong>Preparative columns</strong></h3><p><i>Obtain higher throughput while maintaining your product quality</i></p><h4><strong>Optimized loading parameters</strong></h4><p>Our preparative columns provide optimized properties for the purification of wide array of compounds. Some of their inherent parameters include:</p><ul><li>High surface area for increased loading</li><li>Smooth silica for stable packed beds</li><li>Optimal particle and pore size for outstanding performance</li><li>Exceptional quality of silica for column longevity</li></ul><h4><strong>Uniform media with intact particles</strong></h4><p>Our state-of-art packing process eliminates potential bed collapse and ensures longer column lifetime. The combination of optimal slurry amounts and packing<br>pressure significantly reduces column-to-column variability. As a result, each column contains uniform stationary phase with optimal packing density.</p><h4><strong>Technical information</strong></h4><ul><li><strong>Particle Size [μm]:</strong> 5</li><li><strong>Pore Size [Å]:</strong> 120</li><li><strong>Surface Area [m²/g]:</strong> 300</li><li><strong>pH Stability:</strong> 2-8</li><li><strong>Max. Pressure [bar]: </strong>200</li><li><strong>Max. Temperature:</strong> 50 °C</li><li><strong>Silica Morphology:</strong> Spherical, fully porous</li><li><strong>Endcapping:</strong> Yes</li></ul><p>Moreover, you can order custom column dimensions along with preferred particle size.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Galochrom_Method_Development_and_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_ac8fd1acff.jpg" alt="Galochrom: Preparative Chiral ION-QN &amp; Chiral ION-QD columns." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Galochrom_Method_Development_and_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_Preparative_Chiral_ION_QN_and_Chiral_ION_QD_columns_ac8fd1acff.jpg 245w," sizes="100vw" width="2026" height="1229"></p><h3><strong>Order information</strong></h3><h4><strong>Analytical Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION01-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 3</strong></li><li>Porosity: [Å] 200</li><li>Cat. No.: ION02-A150</li><li><strong>Price [€]: 1 300</strong></li></ul><p><span style="font-size:12px;">*As an alternative, we can also offer 150x3 mm, 3 μm with 120 Å</span></p><h4><strong>Preparative Columns</strong></h4><h5><strong>Chiral ION-QN</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION03-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION04-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><h5><strong>Chiral ION-QD</strong></h5><ul><li><strong>Dimensions [mm]: 150 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION05-P150</li><li><strong>Price [€]: 9 800</strong></li></ul></li><li><strong>Dimensions [mm]: 250 x 20</strong><ul><li>Porosity: [Å] 120</li><li>Cat. No.: ION06-P250</li><li><strong>Price [€]: 11 300</strong></li></ul></li></ul><blockquote><h3><strong>SPECIAL OFFER 1+1</strong></h3><p><span style="font-size:22px;"><strong>Buy 1 preparative column and get analytical column for FREE</strong></span></p><p>You can choose 150x4 or 250x4 column with the same sorbent as your preparative column.</p></blockquote>

Method Development & Preparative Chiral ION-QN & Chiral ION-QD columns

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Method Development & Preparative Chiral ION-QN & Chiral ION-QD columns

Chiral ION-QN & Chiral ION-QD HPLC columns - Transform Your Chiral Analysis

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