<p><strong>The Preliminary Program is available below.</strong></p>
<ul>
<li><a href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/15mdcw_guidebook_final_99c11401e3/15mdcw_guidebook_final.pdf"><strong>15th MDCW 2024 - Guidebook</strong></a></li>
<li><a href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/abstract_book_15mdcw_final_010224_3d8a7b7258/abstract_book_15mdcw_final-010224.pdf"><strong>15th MDCW 2024 - Abstract book</strong></a></li>
</ul>
<p>The Guidebook and the Abstract book can be downloaded when available. The Guidebook contains the program and all other pertinent conference information.</p>
<blockquote>
<p><strong>Historical content from the workshop can be found on YouTube via the LabRulez platform: <a href="https://www.youtube.com/playlist?list=PLg-M6fM-05MrGrDggkl_UKzzcHPWPmssh"> 14 MDCW Content (LabRulez)</a></strong></p>
</blockquote>
<p><strong>Thank you to our sponsors for making this event possible</strong>. It is your generous support that enriches the conference program and allows us to operate the conference with <strong>free registration for all attendees</strong>.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_Sponzors_and_Partners_15th_Multidimensional_Chromatography_Workshop_MDCW_2024_b46a541625/MDCW-Sponzors-and-Partners-15th-Multidimensional-Chromatography-Workshop-(MDCW)-2024.jpg" alt="MDCW: Sponzors &amp; Partners: 15th Multidimensional Chromatography Workshop (MDCW) 2024"/></p>
<blockquote>
<h3><strong>Sponsors 2024</strong></h3>
<ul>
<li><strong>SepSolve Analytical</strong></li>
<li><a href="https://gcms.labrulez.com/library?instrumentationItems=2&amp;manufacturerItems=24"><strong>JEOL</strong></a></li>
<li><a href="https://gcms.labrulez.com/library?instrumentationItems=2&amp;manufacturerItems=25"><strong>LECO</strong></a></li>
<li><a href="https://gcms.labrulez.com/library?mainauthorItems=41&amp;search=GC+image"><strong>GC Image</strong></a></li>
<li><strong>SpectralWorks</strong></li>
<li><a href="https://gcms.labrulez.com/library?instrumentationItems=2&amp;manufacturerItems=9"><strong>Restek</strong></a></li>
<li><strong>NSF CREST CATSUS</strong></li>
<li><strong>OFFICE OF RESEARCH, SCHOLARSHIP AND CREATIVE ACTIVITIES</strong> (CAL STATE LA)</li>
<li><strong>SIKAND SITI CENTER</strong> (CAL STATE LA)</li>
<li><a href="https://gcms.labrulez.com/library?mainauthorItems=3"><strong>Thermo Fisher Scientific</strong></a></li>
<li><a href="https://gcms.labrulez.com/library?mainauthorItems=40"><strong>Trajan Scientific</strong></a></li>
<li><strong>Vici</strong></li>
<li><strong>Chemistry matters</strong></li>
</ul>
<h4><strong>MEDIA PARTNERS 2024</strong></h4>
<ul>
<li><strong>The Analytical Scientist</strong></li>
<li><a href="https://gcms.labrulez.com/"><strong>LabRulezGCMS</strong></a></li>
<li><a href="https://lcms.labrulez.com/"><strong>LabRulezLCMS</strong></a></li>
<li><strong>LCGC</strong></li>
</ul>
</blockquote>
<h3><strong>Preliminary Program</strong></h3>
<h4><strong>WEDNESDAY January 10, 2024</strong></h4>
<h5><strong>8:30 - 9:00 AM</strong> Registration</h5>
<h5><strong>9:00 - 9:30 AM Opening Remarks</strong></h5>
<h5><strong>9:30 - 10:00 AM KL-1 - From research to routine analysis - the role of GC×GC in the regulatory space</strong></h5>
<ul>
<li>Sarah Prebihalo</li>
</ul>
<h5><strong>10:00 - 10:30 AM KL-2 - Two-dimensional liquid chromatography for small molecule pharmaceutical analysis – more knowledge in less time</strong></h5>
<ul>
<li>Qinggang Wang</li>
</ul>
<h5><strong>10:30 - 11:00 AM</strong> Coffee Break</h5>
<h5><strong>11:00 - 11:20 AM O-1 - Applications of multi-dimensional liquid chromatography in modern day pharmaceuticals</strong></h5>
<ul>
<li>CJ Venkatramani</li>
</ul>
<h5><strong>11:20 - 11:40 AM O-2 - Essential separations: analysis of aroma oils by one-dimensional and two-dimensional gas chromatography and mass spectrometry</strong></h5>
<ul>
<li>Robert Cody</li>
</ul>
<h5><strong>11:40 - 12:00 PM O-3 - Developing a breath test to diagnose valley fever, an endemic fungal pneumonia</strong></h5>
<ul>
<li>Emily Higgins</li>
</ul>
<h5><strong>12:00 - 1:30 PM</strong> Lunch (<strong>Sponsored by JEOL</strong>)</h5>
<h5><strong>1:30 - 1:50 PM O-4 - Sampling body odor for healthcare monitoring: how to avoid the pitfalls of individual&#39;s odor variations and contaminations by the sampling environment</strong></h5>
<ul>
<li>Elsa Boudard</li>
</ul>
<h5><strong>1:50 - 2:10 PM O-5 - A holistic view of river water quality using passive sampling and GC×GC–TOFMS</strong></h5>
<ul>
<li>Matthew Edwards</li>
</ul>
<h5><strong>2:10 - 2:30 PM O-6 - Non-target screening and contaminant profiling of house dust collected across Europe by comprehensive two-dimensional gas chromatography - mass spectrometry and multi-variate statistical evaluation</strong></h5>
<ul>
<li>Peter Haglund</li>
</ul>
<h5><strong>2:30 - 2:50 PM O-7 - Chemical characterization of the aircraft cabin environment utilizing GC×GC-TOFMS and hard and soft ionization</strong></h5>
<ul>
<li>Kevin Hayes</li>
</ul>
<h5><strong>2:50 - 4:00 PM</strong> Coffee Break and Poster session</h5>
<h5><strong>4:00 - 5:30 PM Guided Discussion 1 - Advantages and Limitations of GC×GC in Government and Industrial Laboratories</strong></h5>
<h5><strong>6:30 PM Networking Event (Food sponsored by Chemistry Matters Inc)</strong></h5>
<h4><strong>THURSDAY January 11, 2024</strong></h4>
<h5><strong>8:30 - 9:00 AM</strong> Registration</h5>
<h5><strong>9:00 - 9:30 AM Opening Remarks</strong></h5>
<h5><strong>9:30 – 10:00 AM KL-3 - On-line multi-dimensional LC/MS: the next-generation tool for real-time monitoring of antibody quality attributes in biopharmaceutical processes</strong></h5>
<ul>
<li>Tomas Bouvarel</li>
</ul>
<h5><strong>10:00 - 10:30 AM KL-4 - From wildfire origins to courtroom verdicts: Exploring arson investigations with multi-dimensional chromatography</strong></h5>
<ul>
<li>Gwen O&#39;Sullivan</li>
</ul>
<h5><strong>10:30 - 11:00 AM</strong> Coffee Break (<strong>Sponsored by SepSolve Analytical</strong>)</h5>
<h5><strong>11:00 - 11:20 AM O-8 - Don’t let the reality of GC×GC-MS data burst your bubble! Or how the &amp;@$#%^&amp; am I supposed to manage all these bits and bytes?!?</strong>*</h5>
<ul>
<li>James Harynuk</li>
</ul>
<h5><strong>11:20 - 11:40 AM O-9 - Streamlining group type analysis with standard GC×GC templates through computer vision-assisted alignment</strong></h5>
<ul>
<li>Daniel Geschwender</li>
</ul>
<h5><strong>11:40 - 12:00 PM O-10 - Chromatographic and statistical workflows for GC×GC-MS data processing</strong></h5>
<ul>
<li>Scott Campbell</li>
</ul>
<h5><strong>12:00 - 1:30 PM</strong> Lunch (<strong>Sponsored by Cal State LA’s California Forensic Science Institute</strong>)</h5>
<h5><strong>1:30 - 1:50 PM 0-11 - Off-line LC×SFC-HRMS/MS method for the non-target analysis of depolymerised lignin</strong></h5>
<ul>
<li>Eliise Tammekivi</li>
</ul>
<h5><strong>1:50 - 2:10 PM 0-12 - Using two-dimensional gas chromatography for determining biogenic components in renewable transportation fuel blends</strong></h5>
<ul>
<li>Rafal Gieleciak</li>
</ul>
<h5><strong>2:10 - 2:30 PM 0-13 - Alkene quantification in plastic waste-derived alternative fuels using GC×GC-FID</strong></h5>
<ul>
<li>Genesis Barzallo</li>
</ul>
<h5><strong>2:30 - 2:50 PM 0-14 - Characterization and quantitative hydrocarbon group-type analysis of plastic-derived pyrolysis oils by GC×GC-TOFMS/FID</strong></h5>
<ul>
<li>Christina Kelly</li>
</ul>
<h5><strong>2:50 – 3:00 - Cutting the ribbon: A visit inside the LECO Complex Chemical Composition Analysis Laboratory</strong></h5>
<ul>
<li>Petr Vozka</li>
</ul>
<h5><strong>3:00 - 4:00 PM</strong> Coffee Break and Poster Session</h5>
<h5><strong>4:00 - 5:30 PM Guided Discussion 2 - Standard Reference Test Mixture for Comprehensive Two-Dimensional Gas Chromatography</strong></h5>
<h5><strong>6:00 PM Wine Tasting Event (Sponsored by LECO)</strong></h5>
<h4><strong>FRIDAY January 12, 2024</strong></h4>
<h5><strong>8:30 - 9:00 AM</strong> Registration</h5>
<h5><strong>9:00 - 9:10 AM Opening Remarks</strong></h5>
<h5><strong>9:10 - 9:40 AM O-15 Robert Synovec - Expanding the scope of tile-based GC×GC–TOFMS data analysis</strong></h5>
<h5><strong>9:40 - 10:10 AM O-16 - Workflow democratization of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry data</strong></h5>
<ul>
<li>Michael Sorochan Armstrong</li>
</ul>
<h5><strong>10:10 - 10:45 AM</strong> Coffee &amp; Brunch</h5>
<h5><strong>10:45 - 11:05 AM O-17 - Investigating sensory-classified roasted arabica coffee with GC×GC-TOFMS and chemometrics to understand potato taste defect</strong></h5>
<ul>
<li>Caitlin Cain</li>
</ul>
<h5><strong>11:05 - 11:25 AM O-18 - Exploring the cup of coffee using GC×GC-MS combined with multiple combination of headspace extractions</strong></h5>
<ul>
<li>Michael Wilde</li>
</ul>
<h5><strong>11:25 - 11:45 AM O-19 - Advancing fingerprint deposition modeling through the integration of comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry for age estimation</strong></h5>
<ul>
<li>Elena Mosham</li>
</ul>
<h5><strong>11:45 - 12:00</strong> AM Break</h5>
<h5><strong>12:00 - 12:20 PM O-20 Cai Huamin - Direct flow modulation method for comprehensive two-dimensional gas chromatography</strong></h5>
<ul>
<li>Cai Huamin</li>
</ul>
<h5><strong>12:20 - 12:40 PM O-21 - LC×SFC valve technologies: guidelines towards a successful online modulation</strong></h5>
<ul>
<li>Margaux Sanchez</li>
</ul>
<h5><strong>12:40 - 1:00 PM O-22 - Extending analyte boiling point range using thinner film porous layer open tubular columns paired with GC×GC-MS</strong></h5>
<ul>
<li>Lina Mikaliunaite</li>
</ul>
<h5><strong>1:00 - 1:20 PM O-23 - Introducing automated online multicolumn two-dimensional liquid chromatography screening as a rapid and efficient tool for method development of multiple pipeline modalities</strong></h5>
<ul>
<li>Heather Wang</li>
</ul>
<h5><strong>1:20 – 1:40 PM</strong> Closing</h5>
<h5><strong>1:40 PM Food Truck Farewell</strong></h5>
<h3><strong>POSTER LIST</strong></h3>
<h5><strong>P-1 Development of a fisher ratio contrast metric for simultaneous discovery of compounds indicating either molding kinetics or bean geographical region in moisture damaged cocoa beans</strong></h5>
<ul>
<li>Lina Mikaliunaite</li>
</ul>
<h5><strong>P-2 Multi-omics workflow for blood serum screening using GC×GC-TOFMS</strong></h5>
<ul>
<li>Pierre-Hugues Stefanuto</li>
</ul>
<h5><strong>P-3 From data to decisions: using novel software tools for automated pairwise comparison of GC×GC data</strong></h5>
<ul>
<li>Matthew Edwards</li>
</ul>
<h5><strong>P-4 Assessment of exhaled breath voc stability on TENAX® GR thermal desorption tubes</strong></h5>
<ul>
<li>Trenton Davis</li>
</ul>
<h5><strong>P-5 Characterization and comparison of fresh and dried herbs with GC, GC×GC, and TOFMS</strong></h5>
<ul>
<li>Elizabeth Humston-Fulmer</li>
</ul>
<h5><strong>P-6 Comparison of new and used vacuum pump oil using two-dimensional gas chromatography and high-resolution time-of-flight mass spectrometry</strong></h5>
<ul>
<li>Kirk Jensen</li>
</ul>
<h5><strong>P-7 Non-targeted analysis of environmental samples using comprehensive gas chromatography (GC×GC-) with high-resolution time-of-flight mass spectrometry (HRTOFMS)</strong></h5>
<ul>
<li>David Alonso</li>
</ul>
<h5><strong>P-8 Identifying putative volatile biomarkers for S. aureus methicillin-resistant and small-colony variant subtypes</strong></h5>
<ul>
<li>Daniela Gutierrez-Munoz</li>
</ul>
<h5><strong>P-9 Automated QC pooling by thermal desorption tube recollection of gaseous mixtures for metabolomic studies</strong></h5>
<ul>
<li>Allison Ferranti</li>
</ul>
<h5><strong>P-10 Identifying the primary sources of variance in a breath biomarker experiment</strong></h5>
<ul>
<li>Darakshan Zabin</li>
</ul>
<h5><strong>P-11 A feasibility study of sample recollection in the analysis of selected volatile organic compounds in breath samples using GC×GC-ToFMS</strong></h5>
<ul>
<li>Nina Nouribakikomarolya</li>
</ul>
<h5><strong>P-12 Development and application of a web-based simulator for two-dimensional liquid chromatography separations</strong></h5>
<ul>
<li>Dwight Stoll</li>
</ul>
<h5><strong>P-13 Flow modulated GC×GC in combination with atmospheric pressure mass spectroscopy using the SICRIT ionization source</strong></h5>
<ul>
<li>Taylor Hayward</li>
</ul>
<h5><strong>P-14 Comparison of diesel samples measured by using GC×GC-HRTOFMS</strong></h5>
<ul>
<li>John Dane</li>
</ul>
<h5><strong>P-15 Optimization of headspace solid-phase microextraction of bronchoalveolar lavage samples from people with cystic fibrosis and method evaluation</strong></h5>
<ul>
<li>Antao Gao</li>
</ul>
<p><em>The poster list will be updated with last minute posters.</em></p>
<h4><strong>Keynote Speakers 2024</strong></h4>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_Keynote_Speakers_2024_Dr_Gwen_O_Sullivan_Dr_Sarah_Prebihalo_Dr_Qinggang_Wang_Dr_Thomas_Bouvarel_1d428b3bb9/MDCW-Keynote-Speakers-2024-Dr.-Gwen-O'Sullivan-Dr.-Sarah-Prebihalo-Dr.-Qinggang-Wang-Dr.-Thomas-Bouvarel.jpg" alt="MDCW: Keynote Speakers 2024: Dr. Gwen O&#39;Sullivan, Dr. Sarah Prebihalo, Dr. Qinggang Wang, Dr. Thomas Bouvarel"/></p>
<h5><strong>Dr. Gwen O&#39;Sullivan</strong></h5>
<ul>
<li>Professor &amp; Vice Dean Research &amp; Scholarship, Mount Royal University</li>
</ul>
<p><strong>Title of Keynote Lecture: From Wildfire Origins to Courtroom Verdicts: Exploring Arson Investigations with Multidimensional Chromatography</strong></p>
<p>Gwen is an environmental chemist specializing in Environmental Forensics, particularly in wildfire forensics, arson investigation, air monitoring, and risk assessment. She combines analytical chemistry and environmental science to study the origins and behavior of pollutants and their environmental impacts.  Over the course of her career, in industry, consultancy, and academia, Gwen has developed technical expertise in the areas of wildfire forensics, environmental chemistry, environmental forensics, air quality, and contaminated land and groundwater. She has worked environmental forensic investigations involving compounds of concerns including ignitable liquids, drilling fluids, petroleum hydrocarbons, polycyclic aromatic hydrocarbons, polychlorinated biphenlys, polychlorinated dibenso-p-dioxins and dibenzofurans, methane, and nitrates. She has also authored numerous scientific articles, edited book series, and successfully competed for research grants both nationally and internationally.​</p>
<h5><strong>Dr. Sarah Prebihalo</strong></h5>
<ul>
<li>Chemist, U.S. Food and Drug Administration</li>
</ul>
<p><strong>Title of Keynote Lecture: From research to routine analysis - The role of GC×GC in the regulatory space</strong></p>
<p>​​​Sarah Prebihalo is a Chemist at the U.S. Food and Drug Administration in Maryland as a part of the Office of Regulatory Science at the Center for Food Safety and Applied Nutrition (CFSAN). Sarah worked as a laboratory technician at Procter and Gamble for 2 years after obtaining her Bachelor’s in Chemistry, before moving to Pennsylvania to obtain her Masters in Forensic Chemistry at Penn State. In 2015 she began working towards her PhD in Chemistry at the University of Washington in Seattle, which she obtained in 2020. After completing a 2 year postdoctoral fellowship at the U.S. Food and Drug Administration, she transitioned to her current role as Chemist and is involved in non-targeted method development for foods and dietary supplements using GC×GC. ​</p>
<h5><strong>Dr. Qinggang Wang</strong></h5>
<ul>
<li>Scientific Director, Chemical Process Development, Bristol Myers Squibb</li>
</ul>
<p><strong>Title of Keynote Lecture: Two-dimensional liquid chromatography for small molecule pharmaceutical analysis – more knowledge in less time</strong></p>
<p>​​​Qinggang Wang, Ph.D., is a Scientific Director in Chemical Process Development in Bristol-Myers Squibb Company.  He received his B.S. in Chemistry and Ph. D. in Analytical Chemistry from Tsinghua University, Beijing, China.  His work has been focused on CMC analytical supports for various projects within BMS portfolio, inclding small molecules, synthetic peptides and oligonuleotides.  He has authored or co-authored 18 peer-reviewed publications and three book chapters in analytical science. His research focuses on application of novel analytical techniques to pharmaceutical analysis.  He is the recipient of BMS BMSIARC award for outstanding achievement in analytical science in 2019.</p>
<h5><strong>Dr. Thomas Bouvarel</strong></h5>
<ul>
<li>Senior Scientist, Department of Analytical Protein Chemistry, Genentech</li>
</ul>
<p><strong>Title of Keynote Lecture: On-line Multi-Dimensional LC/MS: The Next-Generation Tool for Real-Time Monitoring of Antibody Quality Attributes in Biopharmaceutical Processes</strong></p>
<p>Thomas Bouvarel is currently Senior Scientist in the Department of Analytical Protein Chemistry at Genentech (a member of Roche group) in South San Francisco, California. He received his Ph.D. in analytical chemistry from Sorbonne University, France. After completing a postdoctoral fellowship at the University of Geneva, Switzerland, he joined Genentech. His research involves the development and implementation of novel multi-dimensional liquid chromatography methodologies for the characterization and on-line monitoring of biomacromolecules.</p>
<h3><strong>Guided Discussion Groups 2024</strong></h3>
<h5><strong>Advantages and Limitations of GC×GC in Government and Industrial Laboratories</strong></h5>
<ul>
<li>Haleigh Boswell (Chevron Technology Center)</li>
<li>Sarah Prebihalo (U.S. Food and Drug Administration)</li>
</ul>
<p>​Comprehensive gas chromatography (GC×GC) is a common technique used in government and industrial laboratories; however, it has struggled to gain widespread acceptance due to perceived complexity and a lack of standardized and validated methods. Furthermore, the technique is not directly comparable to historical data sets and previously used analytical techniques. Overcoming these challenges and limitations in non-academic laboratories is a critical aspect of research by experts and advanced GC×GC users. Advanced users must be vocal advocates, highlighting the advantages of GC×GC in cases where the additional separation data can be advantageous. By addressing the benefits and limitations of this technique, this discussion will aim to address how we may elevate GC×GC in industrial and government laboratories, including, but not limited to, the role of obtaining employment in these sectors, allowing for further integration into the GC×GC community.</p>
<h5><strong>Preliminary Results in the Development of a System Performance Standard Reference Test Mixture for Comprehensive Two-Dimensional Gas Chromatography</strong></h5>
<ul>
<li>Jean-Marie D. Dimandja (FDA/ORA)</li>
<li>Pierre-Hugues Stefanuto (University of Liege)</li>
</ul>
<p>GC×GC system performance is influenced by many parameters, including modulator type, column set, detection method, and data processing software. This discussion will be focused on the development of a standard test mixture that can be used to compare GC×GC system performance across instruments and laboratories.</p>


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The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

15th MDCW 2024 (Preliminary Program)

Upcoming events

SCIEX at EPRW 2026

Restek at EPRW 2026

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Biopharma fundamentals: Fragment analysis by CE

Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Improving RNA Purity and Measurement for Reliable Bioprocessing