Dear Customers, Dear Business Partners!
We cordially invite you to visit our booth A1.500 at the <a href="https://lcms.labrulez.com/events/567">Analytica Exhibition</a>. Come to see the latest version of Clarity Chromatography Software and meet our sales and support team!
We are thrilled to showcase the latest version of <a href="https://lcms.labrulez.com/products/999">Clarity Chromatography Software</a>. Our team will be available to answer your questions and discuss your software requirements.
Explore our showcases at Analytica! Experience the unparalleled versatility of <a href="https://gcms.labrulez.com/products/999">Clarity Chromatography Software</a>, which controls 1000+ instruments and supports various applications such as <a href="https://lcms.labrulez.com/products/1001">PDA</a>, <a href="https://lcms.labrulez.com/products/1004">GPC</a>, <a href="https://lcms.labrulez.com/products/1003">MS</a>, <a href="https://lcms.labrulez.com/products/1005">CE</a>, etc. We will also present solutions for instrument manufacturers.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Data_Apex_participates_in_the_Analytica_exhibition_in_Munich_April_9_12_2024_fec53b90b2/DataApex-DataApex-participates-in-the-Analytica-exhibition-in-Munich-April-9-12-2024.jpg" alt="DataApex: DataApex participates in the Analytica exhibition in Munich, April 9-12, 2024"/>
<h3>Don&#39;t miss our special presentations at our BOOTH A1.500</h3>
<h4>Tuesday 9.4.2024 - 11:00</h4>
<h5>Which instrument? Sure, we can control it!</h5>
<ul>
<li>Experience the unparalleled versatility of Clarity Chromatography Software, capable of seamlessly controlling over 1000 instruments from various vendors, all within one user interface.</li>
</ul>
<h4>Wednesday 10.4.2024 - 11:00</h4>
<h5>Customization and automation in your hands</h5>
<ul>
<li>Discover how you can make your work in Clarity more efficient. Learn valuable tips and techniques to boost your productivity. Don&#39;t miss this opportunity to optimize your chromatography processes!</li>
</ul>
<h4>Thursday 11.4.2024 - 11:00</h4>
<h5>Always hungry for new control modules!</h5>
<ul>
<li>Join us to learn how to add /develop new drivers, empowering you to integrate additional instruments and expand Clarity&#39;s capabilities.</li>
</ul>
<blockquote>
Would you like to arrange a personal meeting with us?
</blockquote>
<blockquote>
Please <a href="sales@dataapex.com">contact</a> our sales and marketing.
</blockquote>
Detailed information about the exhibition on <a href="https://analytica.de/en/">analytica.de</a>.
We look forward to meeting you in Munich!
DataApex team

DataApex: See you at Analytica 2024

Dear customers and business partners,
We are happy to announce our latest version of Clarity 9.1. This version introduces new control modules for Chromsystems, ECOM, and Welch. It also includes updated Advion, ECOM, Labio, NETEL, Sykam, YoungIn Chromass, and Agilent ICF control modules. A detailed list of changes is available in the What is new section on our web.
This update is available to existing <a href="https://gcms.labrulez.com/products/999">Clarity 9.0</a> users at no additional cost.
<blockquote>
<h4><a href="https://www.dataapex.com/download?product_filter=3&amp;utm_campaign=Clarity%209.1&amp;utm_medium=email&amp;utm_id=MKT1871&amp;utm_source=newsletter">DOWNLOAD CLARITY</a></h4>
</blockquote>
If you are using a version prior to 9.0, please review our upgrade policy. We recommend upgrading to the latest software version. By doing so, you will not only gain access to the newest features but also benefit from our expert technical support, which is provided for free with our latest software versions.
Your DataApex team
<h3>Tha latest literature on Clarity software from DataApex in <a href="https://gcms.labrulez.com/library?from=2023&amp;mainauthorItems=95&amp;search=Clarity&amp;sources=LCMS_EN-ICPMS_EN-GCMS_EN&amp;to=2024">LabRulez Library</a></h3>
<ul>
<li>REGULATED ENVIRONMENT IN REGARD TO CLARITY (Presentations | 2023)
</li>
<li>Clarity VALIDATION (Presentations | 2023)
</li>
<li>Clarity Software + Hardware VALIDATION KIT (Manuals | 2023)
</li>
<li>Why Clarity Chromatography Software? (Presentations | 2023)
</li>
<li>Clarity Software REFERENCE GUIDE (Manuals | 2023)
</li>
<li>Clarity SST – SYSTEM SUITABILITY TEST CLARITY EXTENSION (Presentations | 2023)
</li>
<li>Declaration of Software Validation - Structural validation and Statement of compliance with 21 CFR Part 11 (Others | 2023)
</li>
</ul>

DataApex Clarity 9.1 released

<h3>Promotion Alert!</h3>
For a limited time, customers who replace their existing chromatography software or integrator with <a href="https://lcms.labrulez.com/products/999">Clarity</a> or Clarity Lite Chromatography Software will receive a 20% discount on the software! This promotion is applicable also for old DataApex software (CSW17/CSW32). The promotion is valid through August 31, 2024.
Please contact <a href="https://www.dataapex.com/">DataApex</a> or your <a href="https://lcms.labrulez.com/products/999">distributor</a> for more details.
<h4>Why migrate to Clarity/Clarity Lite?</h4>
<ul>
<li>User-friendly interface.</li>
<li>Scalable solution.</li>
<li>Comprehensive data analysis tools.</li>
<li>Wide range of over 1000 controlled instruments.</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Replace_your_current_Chromatography_Software_with_Clarity_and_Save_Big_190b40fbee.jpg" alt="DataApex: Replace your current Chromatography Software with Clarity and Save Big!"/>

Replace your current Chromatography Software with Clarity and Save Big!

<h4>Here's what Clarity 10.0 offers:</h4>For a comprehensive function overview, please refer to the full details on our website. Also, check our Upgrade policy.&nbsp;<ul style="margin-top:0px;"><li>Dual Chromatogram Mode: two samples can be measured during one analysis using dual tower or dual loop samplers.</li><li>Extended GLP options for regulated environments.</li><li>Many improvements for Clarity Extensions: MS, PDA, DHA, NGA.</li><li>Updated and new control modules.</li></ul>For a comprehensive function overview, please refer to <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/news/140846/clarity-10-released">the full details on our website</a>. Also, check our <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/product/upgrade">Upgrade policy</a>.Upgrade now and experience Clarity 10.0!<blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/product/clarity-demo">GET FREE DEMO</a><ul><li>Check the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1&amp;version=10.0">What is new</a>.</li><li>Read the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/downloads/140899/view">Clarity (Lite) 10 vs. 9.0</a> guide.</li></ul></blockquote>&nbsp;Thank you for your trust in our products,Your DataApex team<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Dataapex_Clarity_10_released_91e9897b7d.jpg" alt="Dataapex: Clarity 10 chromatography software released" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Dataapex_Clarity_10_released_91e9897b7d.jpg 227w," sizes="100vw" width="800" height="550"><h3><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">DataApex Clarity Chromatography Software</a></h3>Clarity is a chromatography data software for data acquisition, processing, and instrument control in regulated environment. Clarity is a flexible solution for devices from different vendors, supporting different applications.Optional control modules provide integrated control of selected instruments such as GCs, LCs, pumps, detectors, autosamplers, etc. Extensions provide functions for specific separation techniques or calculations such as PDA, GPC analysis, Mass spectrometry, or SST. Clarity can run in English, French, German, Russian, Spanish, and Chinese language. Support technicians and developers are close to their users and ready to provide extensive Support from DataApex.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_3_4adabdd9a6/DataApex-Clarity-Chromatograficky-Software-3.png" alt="DataApex: Clarity Chromatography Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Clarity_Chromatograficky_Software_3_4adabdd9a6/thumbnail_DataApex-Clarity-Chromatograficky-Software-3.png 230w," sizes="100vw" width="1862" height="1265">

Clarity 10 chromatography software released

From all of us at DataApex, we wish you a peaceful Christmas and a bright New Year!&nbsp;<h4>Peaks of the Year: Behind the scenes</h4>Curious about how things are kept running? Here's a glimpse behind the scenes:🤝 5 team-building events brought us closer together. 📅 26 major milestones were met. 🧪 Clarity underwent 3 rounds of testing to ensure top quality.A year of work, learning, and growth - we couldn't have done it without our team and your support! 💙<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Peaks_of_the_Year_Behind_the_scenes_d66fe51286.jpg" alt="DataApex: Peaks of the Year - Behind the scenes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Peaks_of_the_Year_Behind_the_scenes_d66fe51286.jpg 235w," sizes="100vw" width="1086" height="722"><h4>Peaks of the Year: Industry insight</h4>One of the standout advancements in Clarity 10.0 is the Dual Chromatogram Mode - a game-changer for industry professionals. 🚀 This new feature lets you:📊 Measure two samples in one analysis (creating two chromatograms) 📊 Utilize dual-tower samplers (GC) or dual-loop samplers (LC) 📊 Customize parameters for simultaneous measurements.Interested in the Dual Chromatogram Mode? Contact your distributor or us at <a href="mailto:sales@dataapex.com" target="_self" data-test-app-aware-link="">sales@dataapex.com</a> to upgrade to Clarity 10.0. 📥<h4>Peaks of the Year: Milestones of 2024</h4>Starting with what we consider to be the largest milestones of 2024:💎 Release of Clarity 9.1.1 and subsequently Clarity 10.0 💎 Support for the development of MS-MS control modules 💎 Dual chromatogram mode support 💎 Introduction of 27 new control modules (and update of 29)What are your Milestones of 2024? <a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/company/dataapex/posts/?feedView=all">Share in the comments!</a> 💬<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Peaks_of_the_Year_Merry_Christmas_and_Happy_New_Year_8a454c13da.jpg" alt="DataApex: Peaks of the Year: Milestones of 2024" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Peaks_of_the_Year_Merry_Christmas_and_Happy_New_Year_8a454c13da.jpg 236w," sizes="100vw" width="1088" height="720"><h4>Peaks of the Year: Nice to meet you!</h4>Meeting our partners and customers was among our top priorities this year. Here's what we accomplished in 2024:🤝 Participated in multiple international exhibitions 🤝 Organized and contributed to various trainings and webinars 🤝 Engaged with Clarity users from across the globeYour support has made all of this possible - thank you for being a part of our journey! 🥂<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Peaks_of_the_Year_Nice_to_meet_you_b27b9a87f7.jpg" alt="DataApex: Peaks of the Year - Nice to meet you!" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Peaks_of_the_Year_Nice_to_meet_you_b27b9a87f7.jpg 236w," sizes="100vw" width="1088" height="720"><h4>Peaks of the Year: Most popular features</h4>This year, the PDA Extension stole the spotlight as the most popular Clarity extension, included with every 10th license sold in 2024. 🌈 Designed for processing 3D data from photo-diode array (PDA) detectors, it's a must-have for every analyst. 🧑‍🔬Curious about its capabilities? <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1001">Explore the details here</a> 🧑‍💻<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Peaks_of_the_Year_Most_popular_features_aee1f1aad3.jpg" alt="DataApex: Peaks of the Year - Most popular features" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Peaks_of_the_Year_Most_popular_features_aee1f1aad3.jpg 236w," sizes="100vw" width="1088" height="720"><h4>Peaks of the Year: Customer support</h4>Our customers are our top priority. 💙 We're proud to share some highlights from this year's achievements for you:🤝 Resolved over 900 customer-reported incidents 🤝 Introduced a new support request form on our website 🤝 Released 17 new Clarity tutorial videos 🤝 Updated countless Clarity documentation topicsWere you happy with our support in 2024? <a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/company/dataapex/posts/?feedView=all">Share your thoughts in the comments!</a> 💬<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Peaks_of_the_Year_Customer_support_ebad2febff.jpg" alt="DataApex: Peaks of the Year - Customer support" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Peaks_of_the_Year_Customer_support_ebad2febff.jpg 236w," sizes="100vw" width="1088" height="720">

Peaks of the Year: Merry Christmas and Happy New Year

<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1001">The PDA Extension</a> is an optional Extension that is used for processing data that has been acquired from selected photo diode array detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis. This extension expands the capability of Clarity by providing interactive spectral analysis, peak purity analysis and compound identification that is based on a spectral library search. PDA data can be displayed in a set of optional views including 3D rendering.All data is saved in a single file; a chromatogram at any wavelength or even only a spectrum can simply be recalled for review after an analysis. UV-VIS spectra, acquired using a PDA detector, may be interactively selected from a chromatogram signal for visual inspection and comparison. The spectra may also be used for peak purity determinations, wavelength optimization and component identification through spectral libraries.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?manufacturerItems=58&amp;search=pda+extension">The PDA Extension</a> is an optional, fully integrated addition to <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity software</a>.&nbsp;</li><li>It can be ordered as a part of new software or as an extension to existing software.</li><li>The LC-PDA mode is selectable for any LC Instrument within a station.&nbsp;</li><li>The PDA Extension is also compatible with Clarity Offline software.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_PDA_Extension_776dbd48dd.jpg" alt="DataApex - PDA Extension" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_PDA_Extension_776dbd48dd.jpg 245w," sizes="100vw" width="1206" height="534"><h4>Features</h4><ul><li>PDA Data: All data is saved in a single file; a chromatogram at any wavelength or a spectrum only can be simply recalled after an analysis for review. UV-VIS spectra, acquired using a PDA detector, may be interactively selected from a chromatogram signal for visual inspection and comparison. The spectra may also be used for peak purity determinations, wavelength optimization and component identification through spectral libraries.</li><li>PDA View: The PDA view is customizable; up to four views can be displayed at one time (possible views: Isoplot, Chromatogram, Spectra, 3D Display, Peak Purity, Peak Purity Spectra, Library Spectra Search and Spectral Library). The user can easily extract chromatographic signals from PDA data to determine the optimal detection wavelength for each peak.</li><li>PDA Method: The Clarity PDA method includes an option for Spectral Library Search and Peak Purity analysis.</li><li>Peak Purity: This analysis helps to discover hidden impurities. Purity is calculated from 5 or all spectra within the peak. The similarity curve is displayed in the PDA window. Peak Purity analysis can be optimized by setting custom preferences relating to the purity threshold, wavelength restriction and absorbance threshold.</li><li>Spectral Library: The Clarity software compares the peak spectra with the spectra of an unlimited number of spectral libraries. Spectra stored in a Spectral Library include retention times and analysis parameters. The Spectral Library Search can perform automatic identification of integrated/calibrated components (peaks). The library search may be constrained by the RT Window and by Wavelength Range. A Background Correction option is also available.</li><li>Import/Export Data: Spectral data can be imported/exported in ASCII text formats to or from the Clarity software.</li><li>Reports: Users can easily include PDA options such as data 3D Display, Isoplot, Spectra, Peak Purity and Library Search results in reports using the intuitive Report Setup dialog.</li><li>Instrument Control: Control modules (p/n A24) for Agilent, Shimadzu, Knauer and Duratec DADs are available (as of May 2007). Additional control modules for other PDA detectors can be developed upon request.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_The_PDA_Window_displays_four_views_organized_in_splitters_8c614fb6f0.jpg" alt="DataApex: The PDA Window displays four views organized in splitters. Currently displayed in the example are: Isoplot, Chromatogram, Spectral, 3D Display The user can additionaly select also Peak Purity, Peak Purity Spectra, Library Spectra Search and Spectral Library." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_The_PDA_Window_displays_four_views_organized_in_splitters_8c614fb6f0.jpg 191w," sizes="100vw" width="1098" height="896"><h4>Specification</h4><ul><li>Part No.: A29</li><li>Related Products:&nbsp;<ul><li>Clarity (p/n C50) - required</li><li>Clarity offline (p/n C59)</li><li>LC Control (p/n A24) - see the list of available PDA detectors at www.dataapex.com</li></ul></li></ul>

Clarity software - PDA (Photodiode Array) Extension

<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/60">DataApex</a> is pleased to announce that Clarity 10 now supports the ECDM2000 conductivity and pH monitor from <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168">Ecom</a>! This new driver enhances Ecom instrumentation support, with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?manufacturerItems=217&amp;search=LED20M+LED20G">LED20 UV detector compatibility</a> coming in the next software update (10.1.).But this update is more than just about technology—it's about partnership. Our collaboration with Ecom goes way back. Both companies are at home in the Czech Republic, with offices nearby. Ecom purchased their first Clarity software licenses back in 1992!We deeply value our strong relationships—not just with Ecom, but with all our partners worldwide. Behind Clarity Chromatography Software stands a long history shaped by dedicated people and business partners.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_10_now_supports_ECOM_systems_36cd266637.jfif" alt="DataApex: Clarity 10 now supports the ECDM2000 conductivity and pH monitor from Ecom" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Clarity_10_now_supports_ECOM_systems_36cd266637.jfif 222w," sizes="100vw" width="1280" height="900"><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">DataApex Clarity Chromatography Software</a></h4>Optional control modules provide integrated control of selected instruments such as GCs, LCs, pumps, detectors, autosamplers, etc. Extensions provide functions for specific separation techniques or calculations such as PDA, GPC analysis, Mass spectrometry, or SST. Clarity can run in English, French, German, Russian, Spanish, and Chinese language. Support technicians and developers are close to their users and ready to provide extensive Support from DataApex.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_f77d0405d2/DataApex-Clarity-Chromatograficky-Software.jpg" alt="DataApex: Clarity Chromatography Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Clarity_Chromatograficky_Software_f77d0405d2/thumbnail_DataApex-Clarity-Chromatograficky-Software.jpg 245w," sizes="100vw" width="800" height="487"><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1480">ECOM ECDM2100 conductivity and pH monitor</a></h4>ECDM 2100 are conductivity and pH monitors suited for preparative and flash chromatography. Thanks to the unique ECOM design of the conductivity cell, it radically improves chromatography process monitoring.The monitor cell had been developed for high-pressure applications, which means it can be used in CaptureSMB applications. These applications utilize a twin-column periodic countercurrent (PCC) process used for the continuous purification of monoclonal antibodies.The unit is controlled by a printed board, which measures the conductivity of liquid passing through both the cell and the pH value.Main features and benefits<ul><li>High-pressure cell up to 17 MPa (for 1/16” version)</li><li>Simple conductivity calibration</li><li>Compact size</li><li>Powered by 12 – 24 V DC</li><li>Sophisticated diagnostic software</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ECOM_ECDM_2100_Conductivity_and_p_H_Monitors_1_03ebfb31de.jpg" alt="ECOM: ECDM2100 Conductivity and pH Monitors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ECOM_ECDM_2100_Conductivity_and_p_H_Monitors_1_03ebfb31de.jpg 156w," sizes="100vw" width="700" height="700"><h3>ECOM LED20 UV detectors</h3><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1465">LED20M FIX Dual UV Detector with display</a></h4>Why choose LED20M FIX detectors for your application<ul><li>The LED detectors allow easy and convenient detection in the UV-VIS range. They are manufactured in single or dual channel models with fixed wavelength setup.</li><li>The detectors are widely used in chromatography techniques using gravity glass columns for purification and isolation of organic small molecules and other compounds of interest. Long-lasting and reliable light source is provided by LED.</li><li>The optical flow cell is easily accessible and replaceable, this feature allows flexible choice of detection sensitivity if required. Low cell heating due to low power dissipation of LEDs makes this detector ideal for applications where analytes may be susceptible to degradation due to elevated temperatures. Absorbance information is displayed in detail on the integrated OLED display in numerical and graphical formats.</li><li>The units have convenient USB-C connectivity and power. When the detector is connected to a PC, the recorded data can be stored and processed using the ECOMAC software. ECOMAC basic software license is available with the price of the product without any additional fees. All these features and capabilities allow LED20M FIX to be an affordable, cost-effective, reliable and robust choice of an UV-VIS detector.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ECOM_LED_20_M_FIX_Dual_UV_Detector_with_display_2_e79b6687c9.jpg" alt="ECOM - LED20M FIX - UV Detector with display - 2.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ECOM_LED_20_M_FIX_Dual_UV_Detector_with_display_2_e79b6687c9.jpg 217w," sizes="100vw" width="700" height="505"><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1467">LED20M FIX Single UV Detector with display</a></h4>The LED20M FIX Single UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1469">ECOM LED20G Dual UV Detector</a></h4>LED20G Dual UV LED detector for preparative and flash liquid chromatography. LEDs (Light Emitting Diodes) are used as the light source. A unique and patented ECOM technology radically improves the detector characteristics.The LEDs themselves typically have a peak wavelength with a tolerance of +/- 5 nm and a spectral half-width of 10-20 nm, which is unacceptable for some applications, as e.g. for FPLC. This ECOM solution, however, allows the spectral width to be narrowed and, thanks to our patented technology, the exact wavelength to be selected from the LED spectrum.This version of the dual UV detector measures at two fixed wavelengths given by the installed LEDs. The default wavelengths are 254 and 280 nm. Optionally, the customer can select a wavelength in the range 254-600 nm in 1 nm steps.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ECOM_ECOM_LED_20_G_Dual_UV_Detector_e95e74b3cf.jpg" alt="ECOM: LED20G Dual UV Detector" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ECOM_ECOM_LED_20_G_Dual_UV_Detector_e95e74b3cf.jpg 156w," sizes="100vw" width="700" height="700"><h3>Webinars related to Clarity chromatography software from our LabRulez portal:</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/4696">Clarity 10 Webinar</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/3999">Clarity Chromatography Software live demo</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/3350">Clarity Tips &amp; Tricks Webinar</a></li></ul><h3>A selection of DataApex literature focusing on Clarity software <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?from=2022&amp;manufacturerItems=58&amp;search=Clarity+software&amp;to=2025">in the LabRulezLCMS library</a>:</h3><ul><li>Why Clarity Chromatography Software? (Presentations | 2023)</li><li>Clarity Software REFERENCE GUIDE (Manuals | 2023)</li><li>Clarity Software USER GUIDE (Manuals | 2022)</li><li>INTRODUCTION TO CLARITY CHROMATOGRAPHY SOFTWARE (Presentations | 2022)</li><li>Clarity DISTRIBUTOR TRAINING Installation &amp; Configuration (Presentations | 2022 )</li><li>Clarity Software + Hardware VALIDATION KIT (Manuals | 2023)</li><li>Clarity Lite Software GETTING STARTED (Manuals | 2022)</li><li>Clarity Control Module SHIMADZU NEXERA (Manuals | 2022)</li><li>Clarity VALIDATION (Presentations | 2023)</li></ul>

Clarity 10 now supports the ECDM2000 conductivity and pH monitor from Ecom

<h3>Introduction</h3>This document presents:<ul><li>a comparison of integration algorithms (IAs) available in <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/999">Clarity</a>,</li><li>a generally proposed workflow for integrating chromatograms,</li><li>description of functions that are available only in the Wave algorithm.</li></ul>Integration algorithms are a crucial component of any chromatography software. They identify peaks in a raw chromatographic curve, assign integration marks (starts, ends, apexes), and determine the peak baseline. Although it is the operator's responsibility to verify the correct peak integration after the analysis is finished, an automated peak detection facilitated by the integration algorithm can significantly streamline the workflow.Clarity since version 9.0 offers two IAs: the original algorithm, renamed Legacy, and a newly introduced algorithm named Wave, which evolved from an experimental algorithm present since version 7.0. The Wave algorithm will be regularly updated with new functions, settings, and bug fixes (updates for Legacy will only be released if a critical bug is discovered). Changes in IAs are always versioned and distinguishable by records in the audit trail.<h3>Choosing an integration algorithm</h3>Users can select either the Legacy or Wave integration algorithm for peak detection. The IA drop-down selection has been relocated to the Integration tab in both the Chromatogram window and the Method Setup dialog, highlighting the interconnection between the algorithm and the integration table.The introduction of Wave does not affect existing results or methods, as they will remain set to Legacy unless manually altered. Suppose a method was created using an older version of any integration algorithm and was not changed after the Clarity update to a newer version. In that case, the latest version of the same algorithm will be used in any newly measured chromatograms. This change will be logged in these chromatograms upon creation. To address potential issues, DataApex aims to use the algorithm version with the most bug fixes. Users are not required to re-save their methods, but if they do, the change will be logged in the method audit trail.One way to apply an integration algorithm to multiple chromatograms simultaneously is through the Batch dialog (not applicable to Clarity Lite).<h3>General Comparison</h3>Neither algorithm can be universally deemed superior; some situations may warrant using one IA over the other. Below are some examples of performance differences between the two IAs. At least the Global Peak Width and Global Threshold operations were presumed to be performed on the signal. If you encounter any issues with either of the integration algorithms, please inform DataApex via <a>support@dataapex.com</a>. This datasheet further contains an overview of a basic integration workflow.<h4>Advantages of Wave IA:</h4><ul><li>Handling of negative spikes/peaks with regard to baseline placement.</li><li>Handling of shifting baseline/signal.</li><li>Separation of unresolved peaks.</li></ul><h4>Disadvantages of Wave IA:</h4><ul><li>More sensitive to noise, requiring the use of Bunching or another filter in some cases.</li><li>Incorrect integration when peaks of significantly different widths are present (typical for GPC or EA).</li></ul><h4>Negative spikes/peaks</h4>When a chromatogram contains significant negative peaks or spikes that should not be evaluated, the default integration in the Wave algorithm will produce satisfactory results, while the Legacy algorithm will not. (In Legacy, this problem could be solved by applying several Integration Intervals.)<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_4b4372d5b8.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 1. Integration by Legacy IA considers the negative spike to be the start of the peak (or peak cluster)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_4b4372d5b8.jpg 245w," sizes="100vw" width="1063" height="548"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_11_e51da3eb48.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 2. Integration by Wave IA with the same parameters." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_11_e51da3eb48.jpg 245w," sizes="100vw" width="1061" height="554"><h4>Shifting signal/baseline</h4>Similar to the negative peaks/spikes, the same situation may arise with a shifting baseline where the peaks should be evaluated to that baseline. Legacy IA will provide unsatisfactory integration. In Legacy, this could be solved by applying Baseline Valley to several places and combining them with Integration Interval.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_13_d44f34c303.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 3. Integration by Legacy IA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_13_d44f34c303.jpg 245w," sizes="100vw" width="1064" height="551"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_14_8c3d2772fe.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 4. Integration by Wave IA with the same parameters. The fairly high number of peaks is caused by the low value of the Global Threshold." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_14_8c3d2772fe.jpg 245w," sizes="100vw" width="1062" height="553"><h4>Unresolved Peaks</h4>In Legacy IA, if a peak does not fulfill some criteria (it is too narrow or the valley to other non-resolved peaks is too low), it gets joined to a neighboring bigger peak. Meanwhile, Wave IA evaluates the valley depths much better and separates the peaks automatically, even when the small peak does not fulfill some of the criteria. Small impurities, thus, do not influence the area of the bigger peak of interest.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_10_49fded9390.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 5. Integration by Legacy IA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_10_49fded9390.jpg 245w," sizes="100vw" width="1062" height="554"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_12_6d8d9a6980.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 6. Integration by Wave IA with the same parameters." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_12_6d8d9a6980.jpg 245w," sizes="100vw" width="1062" height="551"><h4>Significant noise</h4>In some cases, the signal noise may be very significant, and the set threshold value in the Wave algorithm will be so low that one peak will be split into several peaks. The example below shows that neither of the IAs is sufficient with just Global Peak Width and Global Threshold; additional operations must be used.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_9_e020e43a49.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 7. Integration by Legacy IA with the same parameters." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_9_e020e43a49.jpg 245w," sizes="100vw" width="1062" height="552"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_8_1b275412a8.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 8. Integration by Wave IA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_8_1b275412a8.jpg 245w," sizes="100vw" width="1064" height="552"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_7_4071029dd3.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 9. Integration by Wave IA after applying Global Bunching. Sometimes, small peaks at the start/end of a bigger one may remain." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_7_4071029dd3.jpg 245w," sizes="100vw" width="1061" height="550"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_6_ee88c557f1.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 10. Integration by Wave IA after applying Global Bunching and Minimal Area parameters." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_6_ee88c557f1.jpg 245w," sizes="100vw" width="1063" height="556"><h4>Peaks with significantly different peak widths</h4>Sometimes, chromatograms have very different peak widths; when some peaks cover a significant portion of the chromatogram (e.g., in EA or GPC), Wave IA may fail to evaluate the wide peaks properly. Currently, it is recommended to integrate these chromatograms using Legacy IA.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_3_b833975244.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 11. Integration by Legacy IA with the same parameters." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_3_b833975244.jpg 245w," sizes="100vw" width="1060" height="549"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_4_660685f241.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 12. Integration by Wave IA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_4_660685f241.jpg 245w," sizes="100vw" width="1060" height="551"><h4>Peaks cut off in the middle</h4>Sometimes, random peaks get integrated strangely in Wave IA, being cut off. This happens only randomly in the Wave IA (in a series of chromatograms, most peaks are OK, but occasional chromatograms may have one or more peaks cut off). The phenomenon results from filtering the data in combination with the signal curve course. There is no 100% solution in the Wave algorithm (applying Global Bunching or other filters helps in most cases). Switching to Legacy IA helps.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_2_ce68c8dc99.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 13. Integration by Wave IA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_2_ce68c8dc99.jpg 245w," sizes="100vw" width="1064" height="553"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_5_af9302130f.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 14. Integration by Wave IA after applying Global Bunching." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_5_af9302130f.jpg 245w," sizes="100vw" width="1061" height="549"><h3>Basic integration workflow</h3>Setting at least the Integration Interval and global parameters before resorting to other operations is recommended. This strategy suffices for most chromatograms, and such integration is then applicable to all similar samples. The recommended order of operations is as follows (refer to the User Guide for a detailed description):<ol><li>Set Integration Interval(s) Some areas of the chromatograms are irrelevant to the analysis and may cause wrong integration of the rest of the chromatogram if left in operation, e.g., sudden steep signal rises/drops when lamps are switched on, mobile phase compositions suddenly changing, etc. Make sure that the Integration Interval operation does not define an interval starting or ending inside of a peak slope; in either IA, the expectation is that the chromatogram starts and ends on a baseline.</li><li>Set Global Peak Width If the chromatogram has peaks with significantly differing peak widths, applying the Local Peak Width operation may be useful later.</li><li>Use Global Bunching operation Global Bunching is calculated based on the chromatogram frequency and the set Global Peak Width, so it should be applied after setting the Global Peak Width.</li><li>Set Global Threshold Based on the Threshold value, the smallest peaks are omitted depending on the noise of the signal curve. Since Global Bunching acts as a signal filter, the automatically suggested Global Threshold value will differ after applying Global Bunching higher than 1.</li></ol><h3>Exclusive features in Wave IA</h3>Wave IA contains some Integration Table functions that are unavailable in Legacy IA. If these functions are present in the Integration Table, they will become invisible (not performed) when switching to the Legacy IA but will remain if the algorithm reverts to Wave.<h4>Peak – Show and Peak – Hide</h4>The Peak – Show and Peak – Hide functions provide a convenient way to manage the visibility of specific peaks in your data. These tools allow you to tailor your display by either showing or hiding specific peaks.By default, the Wave algorithm might automatically ignore some of the minor peaks identified during integration. However, completely eliminating these peaks could potentially affect the baseline's trajectory. Therefore, these functions offer a flexible way to handle unwanted peaks without completely removing them.Both the Peak – Show and Peak – Hide features are complemented by the Baseline – Lock function. This tool completely removes all peaks that have their maxima within a set time interval. This could affect other peaks with maxima outside the specified window, particularly if they share the same baseline.The Peak – Hide function has been designed within the Wave algorithm to address this. It merely hides peaks within the selected time interval instead of eradicating them. These peaks are considered when constructing a joint baseline but excluded from the final calculation and the Result Table. The counterpart function Peak - Show allows you to visualize a previously hidden peak or display peaks automatically hidden by the algorithm.In scenarios where a region of the chromatogram contains hidden peaks and the user executes the Peak – Add Positive/Negative operation, all automatically generated but concealed peaks within the defined time interval are replaced by the newly added peak. This could lead to the cancellation of hidden peaks in areas where the manually added peak is not displayed due to baseline crossing limitations.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Integration_Algorithms_in_Clarity_15_b934973f35.jpg" alt="DataApex: Integration Algorithms in Clarity: Figure 15. Difference between Peak Hide (left) and Baseline Lock (right)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Integration_Algorithms_in_Clarity_15_b934973f35.jpg 245w," sizes="100vw" width="1830" height="285"><h4>Global/Local Baseline Slope</h4>Automatic peak generation on a standard signal curve typically comprises three parts: Peak Start, Peak Apex, and Peak End. The highest signal point determines the location of Peak Apex. At the same time, the positioning of Peak Starts and Peak Ends can vary, potentially being either closer or farther from the Peak Apex, based on user preference. Different settings can be more effective depending on the situation.Before the introduction of the Wave IA, the automatic determination of Peak Starts and Peak Ends was governed by the instantaneous peak slope, calculated using the Global/Local Threshold parameter. If users wanted the automatically generated peak borders closer to the Peak Apex, they had to increase the Threshold value. However, this resulted in raising the detection limit for peaks on the baseline, which could prevent the identification of smaller peaks.Wave IA presents an alternative. It allows users to maintain their chosen Threshold value while separately defining the chromatographic curve slope for detecting Peak Starts and Peak Ends through the use of the Global Baseline Slope or Local Baseline Slope operations. This parameter is not mandatory; users can retain the original slope calculation method by leaving the Global Baseline Slope value set to 0. Any value other than zero will cause a shift in the positions of the Peak Starts and Peak Ends.You can find an approximate value for this function using the Chromatogram – Show Slope/Level function in the Chromatogram window menu. However, altering the Baseline Slope value may result in separating peak clusters into individual peaks or merging separate peaks, and some peaks may not be integrated at all.For specific alterations to the start and/or end positions of individual peaks, the Peak – Start and Peak – End operations remain useful. These functions override the automatically calculated positions for peak start and peak end.

Integration Algorithms in Clarity

Clarity 10.1 expands calibration capabilities to help you work more confidently and efficiently. From clearer guidance and better warnings to flexible internal standard evaluation, this update streamlines calibration development, improves traceability, and supports compliance where it matters most.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_10_1_397aba9bab.jpg" alt="DataApex: Clarity 10.1 released" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Clarity_10_1_397aba9bab.jpg 143w," sizes="100vw" width="849" height="925"><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/P063_Clarity_10_1_New_Features_283323fcd2.pdf">Clarity 10.1 highlights</a></h4><ul><li>ISTD from a different signal</li><li>Determination Coefficient (R2)</li><li>Enhanced calibration warnings and blank handling</li><li>Electronic Signature improvements</li><li>New and updated control modules</li></ul><h5>Internal standard from another signal</h5>Clarity 10.1 introduces support for evaluating results using an internal standard from a different signal within the same chromatogram. This is especially useful for workflows like ICP-MS, where some signals may lack an ISTD peak.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Internal_standard_from_another_signal_2f2ac068f8.jpg" alt="DataApex: Internal standard from another signal" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Internal_standard_from_another_signal_2f2ac068f8.jpg 228w," sizes="100vw" width="380" height="260"><h5>Determination Coefficient (R²)</h5>Clarity now displays the Determination Coefficient (R²) alongside the Correlation Coefficient in each compound's calibration curve tab.Determination Coefficient (R²) gives you a more accurate view of how well your calibration model fits the data - especially valuable during method development and validation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Determination_Coefficient_57673d0ac3.jpg" alt="DataApex: Determination Coefficient" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Determination_Coefficient_57673d0ac3.jpg 228w," sizes="100vw" width="380" height="260"><h5>Enhanced calibration warnings and blank handling</h5>Clarity 10.1 helps you catch issues earlier and set up calibration with greater confidence. Warnings are now more visible and more specific - appearing above both the Results Table and the Calibration Summary Table. When multiple issues occur, an ellipsis appears with full details available on hover.Blank handling has also been clarified: blanks are included only when Ignore Origin is selected. If the origin is used, blanks are excluded, and Clarity now clearly warns and visually shows when a blank is ignored.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Dataapex_Enhanced_calibration_warnings_and_blank_handling_e9fe7fa31e.jpg" alt="Dataapex: Enhanced calibration warnings and blank handling" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Dataapex_Enhanced_calibration_warnings_and_blank_handling_e9fe7fa31e.jpg 228w," sizes="100vw" width="380" height="260"><h5>Signature improvements</h5>Clarity 10.1 improves how signatures are handled, making it easier to understand what is and isn't signed. Chromatograms opened with a linked calibration are always marked Not Signed. Once signed, the mode switches to Stored Calibration, so you always see the final, signed result. Even historical versions now reliably show their signature state and details.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Dataapex_Signature_improvements_a2bebe7875.jpg" alt="Dataapex: Signature improvements" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Dataapex_Signature_improvements_a2bebe7875.jpg 228w," sizes="100vw" width="380" height="260"><blockquote>Explore the complete list of all changes, fixes, and additions in version 10.1.<a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">See the complete changelog</a></blockquote>

Clarity Chromatography Software 10.1 released!

<h4>1. Introduction</h4>This article provides a comprehensive and structured troubleshooting guide for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity chromatography software </a>by DataApex. Based on the instructional video titled “What to do when you have issues with Clarity”, it outlines common errors, diagnostic methods, and recommended procedures for addressing technical problems in both software and hardware configurations.<h4>2. Required Tools and Environment</h4>To effectively troubleshoot Clarity, ensure you have access to the following:<ul><li>Clarity Software (version 9.x or 10.x)</li><li>Hardware key (HW key) – for license authorization</li><li>Windows administrator privileges</li><li>Connected instrumentation (GC/LC systems, A/D converters)</li><li>Diagnostic tools:<ul><li>Windows Event Viewer</li><li>Clarity Device Configuration Manager</li></ul></li></ul><h4>3. Common Errors and Solutions</h4><h5>3.1 File Access Errors</h5>Symptom:<ul><li>Error messages such as: "Unknown error accessing ... Temp\Clarity\$ch1run.raw"</li></ul>Cause:<ul><li>Lack of write permissions to the Temp directory.</li></ul>Solution:<ol><li>Ensure the Windows user has full access to the Temp\Clarity folder.</li><li>Run Clarity as Administrator to bypass restricted permissions.</li></ol><h5>3.2 Hardware Key Not Recognized</h5>Symptoms:<ul><li>"Clarity is unable to find HW key"</li><li>"Missing keylock drivers"</li><li>"Blocked HW key"</li></ul>Causes:<ul><li>Key not plugged in, damaged USB port, or missing driver.</li></ul>Solution:<ol><li>Reinsert the HW key into a direct USB port (avoid USB hubs).</li><li>If drivers are missing or outdated, reinstall the HW key drivers and restart the PC.</li><li>Contact DataApex support if the key is blocked or invalid.</li></ol><h5>3.3 Visual C++ Redistributable Installation Fails</h5>Error:<ul><li>"Exit code: 1618" during Clarity installation.</li></ul>Cause:<ul><li>Another installation is already running (e.g., Windows Update).</li></ul>Solution:<ul><li>Wait for the current installation to finish, restart the system, and rerun the Clarity installer.</li></ul><h5>3.4 Instrument Communication Failure</h5>Error:<ul><li>"Cannot establish communication with XXX SN xxx!"</li></ul>Possible Causes:<ul><li>Instrument is turned off or disconnected.</li><li>Wrong or missing driver.</li><li>Incorrect COM port or IP address.</li></ul>Solution:<ol><li>Power on the instrument and verify all connections.</li><li>Use Clarity → System Configuration → Devices to verify driver and port settings.</li><li>Restart the driver or reassign the port if needed.</li></ol><h5>3.5 RAW File Creation Errors</h5>Error:<ul><li>"Cannot create RAW file"</li><li>"Cannot create $ch1temp.raw"</li></ul>Cause:<ul><li>Clarity fails to rename the RAW file due to a file conflict or improper termination.</li></ul>Solution:<ul><li>Ensure the previous acquisition was closed properly.</li><li>Clear error dialogs and restart the acquisition.</li></ul><h5>3.6 Project Change Requires Restart</h5>Error:<ul><li>"Changing project requires to restart instrument."</li></ul>Solution:<ul><li>Save your changes and allow the instrument to restart as prompted.</li></ul><h5>3.7 Configuration File Corruption or Version Conflict</h5>Errors:<ul><li>"Configuration file is not valid"</li><li>"Incompatible device driver"</li></ul>Cause:<ul><li>Attempting to load a project or method created in a newer software version.</li></ul>Solution:<ol><li>Use backup files provided by Clarity.</li><li>Reconfigure devices manually if needed.</li><li>Install matching drivers compatible with your current Clarity version.</li></ol><h5>3.8 Method and Table Errors</h5>Common Issues:<ul><li>"Fraction table contains overlapping time intervals"</li><li>"Too many peaks in chromatogram"</li><li>"Method file does not match instrument configuration"</li></ul>Solution:<ul><li>Adjust fraction time intervals to prevent overlaps.</li><li>Tweak peak detection settings (width, threshold).</li><li>Modify or recreate the method to reflect hardware changes.</li></ul><h4>4. General Troubleshooting Workflow</h4><ol><li>Reboot your PC – resolves many temporary issues.</li><li>Check file and folder permissions – especially the Temp and project directories.</li><li>Verify hardware connections – including USB and serial ports.</li><li>Update or reinstall drivers – HW key, devices, or Clarity modules.</li><li>Restore from backups – when configuration or method files are corrupted.</li></ol><h4>5. Analysis and Best Practices</h4><ul><li>70% of reported issues are related to permissions, HW key problems, or outdated drivers.</li><li>Always keep Clarity and related drivers updated from the official source.</li><li>Ensure project and method files are compatible with the Clarity version you are using.</li><li>Use administrative privileges when installing or configuring hardware/software.</li></ul><h4>6. Conclusion</h4>Clarity is a robust chromatography software platform, but like any system, it may encounter operational or configuration errors. This guide outlines practical and verified troubleshooting techniques derived from real-world scenarios shown in the DataApex tutorial video.For persistent or unclear issues, consult the DataApex Support Portal for documentation, driver downloads, and direct contact with technical support.<blockquote><h5>Quick Tips Recap</h5><ul><li>Always start with a reboot and check permissions.</li><li>Reinstall drivers if devices or keys are not recognized.</li><li>Use correct project/method versions matching your Clarity installation.</li></ul></blockquote>

Troubleshooting Guide: Resolving Issues with Clarity Chromatography Software

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