SIELC’s Alltesta™ Analyzer is an affordable HPLC analytical system that provides both scientific and educational environments with a convenient, simple solution for measuring small and trace concentrations of various chemicals in products such as milk, baby formula, pet food, pills, household formulations, and more.No difficult sample preparation is necessary, and no prior experience in chromatography or analytical chemistry is required for the operator. Measurements typically take less than 5 minutes, and the Alltesta™ comes with a set of supplies sufficient for 200 analyses.<ul><li>Small foot-print, light-weight, can be used on a small table</li><li>No difficult sample preparation</li><li>Takes only a few minutes to start operating</li><li>No chemical experience is required for instrument user</li><li>User friendly, self explanatory cloud-based software</li><li>Produces easy-to-understand results within 5-10 minutes</li></ul><h4>Alltesta Gradient Automated HPLC Analyzer includes:</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1249">Alltesta™ Power Tower</a> (provides power and cloud connectivity)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1244">Alltesta Mini Autosampler</a> (includes <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1245">Alltesta High-Pressure Switching Valve</a>)</li><li>Two <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1247">Alltesta™ Ultra High Pressure Mini Syringe Pumps</a> for gradient flow</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1248">Alltesta UV-Vis Detector</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_Alltesta_automaticky_HPLC_gradientovy_analyzator_2_6aec49522f.jpg" alt="Bioanalytic / SIELC: Alltesta Gradient Automated HPLC Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_Alltesta_automaticky_HPLC_gradientovy_analyzator_2_6aec49522f.jpg 107w," sizes="100vw" width="1969" height="2881"><h3>Application examples using Alltesta HPLC</h3><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1242">Alltesta HPLC</a> Method for Berberine on <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?manufacturerItems=243&amp;search=Primesep+B">Primesep B</a> by SIELC Technologies</h4>Berberine is a naturally occurring alkaloid found in several plants, including the roots, rhizomes, and stem bark of plants such as Berberis species (barberry), Coptis chinensis (goldthread), and Hydrastis canadensis (goldenseal).<ul><li>Medicinal Properties: Berberine has been used in traditional medicine for its various medicinal properties, including antimicrobial, anti-inflammatory, and antioxidant effects.</li><li>Blood Sugar Regulation: Some studies suggest that berberine may help regulate blood sugar levels and improve insulin sensitivity, making it of interest in diabetes research.</li><li>Cholesterol Management: It has been investigated for potential benefits in managing cholesterol levels.</li><li>Anticancer Properties: Berberine has also shown promise in preclinical studies for its potential anticancer properties.</li></ul>Berberine supplements are available and marketed for various health purposes. In traditional medicine, berberine-containing plants have been used for treating various conditions.<h5>HPLC Method</h5><ul><li>Column: Primesep B, 3.2 x 150 mm, 5 µm, 100 A</li><li>Mobile Phase: MeCN/H2O – 20/80%</li><li>Buffer: H3PO4 -0.1%</li><li>Flow Rate:&nbsp;0.5 ml/min</li><li>Detection:&nbsp;UV 275 nm</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_SIECL_Alltesta_HPLC_metoda_proanalyzu_Berberinu_na_kolone_Primesep_B_od_SIELC_Technologies_444d7c3d9c.jpg" alt="Bioanalytic / SIELC: Alltesta HPLC Method for Berberine on Primesep B by SIELC Technologies" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_SIECL_Alltesta_HPLC_metoda_proanalyzu_Berberinu_na_kolone_Primesep_B_od_SIELC_Technologies_444d7c3d9c.jpg 241w," sizes="100vw" width="775" height="500"><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1242">Alltesta HPLC</a> Method for Prednisone, Methylprednisolone, Prednisolone on <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?manufacturerItems=243&amp;search=Primesep+B">Primesep B</a> by SIELC Technologies</h4>All three compounds have potent anti-inflammatory effects, making them valuable in treating conditions where inflammation plays a role.Prednisone:<ul><li>Mechanism of Action: Prednisone is a synthetic corticosteroid that mimics the action of cortisol, a natural steroid produced by the adrenal glands. It primarily exerts its effects by binding to glucocorticoid receptors and regulating gene expression.</li><li>Medical Uses: It is commonly used to treat inflammatory conditions, autoimmune disorders, allergic reactions, and certain cancers.</li></ul>Prednisolone:<ul><li>Derived Form: Prednisolone is the active form of prednisone. When prednisone is ingested, the liver converts it into prednisolone.</li><li>Mechanism of Action: Similar to prednisone, it has anti-inflammatory and immunosuppressive properties.</li></ul>Methylprednisolone:<ul><li>Potency: Methylprednisolone is considered to be more potent than prednisone.</li><li>Medical Uses: It is used in various conditions, including severe allergic reactions, inflammatory conditions, and as a part of immunosuppressive regimens.</li></ul>HPLC Method<ul><li>Column:&nbsp;Primesep B, 3.2 x 150 mm, 5 µm, 100 A</li><li>Mobile Phase: MeCN/H2O – 35/35%</li><li>Buffer: H3PO4 -0.1%</li><li>Flow Rate:&nbsp;0.5 ml/min</li><li>Detection: UV 275 nm</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_SIELC_Alltesta_HPLC_metoda_pro_Prednison_Methylprednisolon_Prednisolon_na_kolone_Primesep_B_od_SIELC_Technologies_019e25f09c.jpg" alt="Bioanalytic / SIELC: Alltesta HPLC Method for Prednisone, Methylprednisolone, Prednisolone on Primesep B by SIELC Technologies" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_SIELC_Alltesta_HPLC_metoda_pro_Prednison_Methylprednisolon_Prednisolon_na_kolone_Primesep_B_od_SIELC_Technologies_019e25f09c.jpg 224w," sizes="100vw" width="775" height="540"><h4>More examples of Alltesta™-based HPLC methods are available in the LabRulez Library</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/HPLC_Method_for_Analysis_of_Aspirin_in_Alka_Seltzer_Extra_Strength_Effervescent_Aspirin_on_Primesep_100_Column_d33816ae83.pdf">HPLC Method for Analysis of Aspirin in Alka-Seltzer Extra Strength Effervescent Aspirin</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/HPLC_Method_for_Analysis_of_Phenylephrine_Hydrochloride_1_in_Equate_Nasal_Spray_on_Primesep_100_Column_02f2983c25.pdf">HPLC Method for Analysis of Phenylephrine Hydrochloride 1% in Equate – Nasal Spray</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/HPLC_Method_for_Analysis_of_Rockstar_Zero_Carbs_Energy_Drink_with_Caffeine_and_Taurine_on_Primesep_100_Column_c87a85a0b4.pdf">HPLC Method for Analysis of Rockstar Zero Carbs Energy Drink with Caffeine and Taurine</a></li></ul>See this cloud-based example of the 2-Naphthalenesulfonic acid, Allura red, Fast Green FCF, 1,5-Naphthalenedisulfonic acid, Tartrazine separation method <a target="_blank" rel="noopener noreferrer" href="https://chrom.app/share/#/samples/11972/injection/21307/?t=a992fefcdd3647b19f6bed81e182d3d8">here</a>.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_SIELC_Alltesta_Gradient_Automated_Analyzer_example_of_the_2_Naphthalenesulfonic_acid_Allura_red_Fast_Green_FCF_1_5_Naphthalenedisulfonic_acid_Tartrazine_separation_b96e648d63.jpg" alt="Bioanalytic / SIELC: SIELC Alltesta™ Gradient Automated Analyzer - example of the 2-Naphthalenesulfonic acid, Allura red, Fast Green FCF, 1,5-Naphthalenedisulfonic acid, Tartrazine separation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_SIELC_Alltesta_Gradient_Automated_Analyzer_example_of_the_2_Naphthalenesulfonic_acid_Allura_red_Fast_Green_FCF_1_5_Naphthalenedisulfonic_acid_Tartrazine_separation_b96e648d63.jpg 245w," sizes="100vw" width="1914" height="1134">

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Bioanalytic started its operations in 1998. The company was born from a passion for science and the need to provide innovative solutions in the laboratory equipment market, from a small business to a dynamically developing company with an established position.

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