Applications from the field of Pharma & Biopharma from Thermo Fisher Scientific - page 12

Automated, compliance-ready, intact mass confirmation of modified oligonucleotides using an LC-MS platform

Applications

| 2023 | Thermo Fisher Scientific

LC/MS, LC/SQ

Instrumentation

LC/MS, LC/SQ

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

A simple and robust LC-MS method for determination of poly(A) tail length using the Orbitrap Exploris MS systems

Posters

| 2023 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Genotoxic impurity analysis

Technical notes

| 2023 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Coupling ion exchange chromatography with mass spectrometry to characterize charge heterogeneity of mAbs under near-native conditions using a ProPac 3R SCX column

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables

Instrumentation

LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Salt gradient analysis of Protein G using a 3 μm monodisperse SAX chromatography column

Applications

| 2023 | Thermo Fisher Scientific

HPLC, Consumables, LC columns

Instrumentation

HPLC, Consumables, LC columns

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Novel applications of multi-detector HPLC systems in pharmaceutical analysis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Instrumentation

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Myth busting: “You cannot sequence oligonucleotides over 20 to 30 nucleotides long by LCMS/MS” Learn how to routinely sequence 100 nt oligonucleotides

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

LC/UV/HRMS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

3μm monodisperse particles for Ion Exchange Chromatography stationary phases and their impact on the separation of biomolecules

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

Consumables, LC columns

Instrumentation

Consumables, LC columns

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Proteomics

Semi-preparative reversed-phase liquid chromatographic purification of oligonucleotides

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

HPLC, PrepLC

Instrumentation

HPLC, PrepLC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma