Increasing Productivity and Confidence for N-linked Glycan Analysis of Biosimilars Using the BioAccord System

 

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IMPROVING CONFIDENCE AND PRODUCTIVITY FOR N-LINKED GLYCAN ANALYSIS IN BIOTHERAPEUTICS DEVELOPMENT USING AN INTEGRATED UPLC-FLR-HRMS SYSTEM Ximo Zhang; Corey Reed, Henry Shion, Robert Birdsall; Ying Qing Yu Scientific Operations, Waters Corporation, Milford, MA INTRODUCTION RESULTS AND DISCUSSION Due to the…
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Application Note Characterization of Released N-linked Glycans in Biosimilar mAb Drug Products Using the Xevo™ G3 QTof Kellen DeLaney, Yamin Htet, Ying Qing Yu Waters Corporation Abstract As an increasing number of biosimilar monoclonal antibodies (mAb) are being developed, there…
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[ APPLICATION NOTE ] Combining RapiFluor-MS and UNIFI Scientific Information System for a Total N-linked Glycan Solution for Innovator vs. Biosimilar Infliximab Comparisons William R. Alley, Jr. and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION This…
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BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…
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