RECIPE Calibrators & Controls Quality Assurance - Product Catalogue II

Importance of the Topic

Accurate calibration and quality control in clinical and bioanalytical laboratories are essential to ensure the reliability of patient results and to meet regulatory requirements. Matrix-matched calibrators and controls compensate for sample preparation losses and matrix effects, supporting traceable measurements across analytical platforms such as HPLC, LC-MS/MS and photometry.

Goals and Overview of the Article

This summary presents an overview of RECIPE Chemicals’ ClinCal® calibrators and ClinChek® controls product lines. ClinCal® offers over 300 calibrators in urine, plasma, serum, whole blood and dried blood spot matrices, covering therapeutic drug monitoring, porphyrins, amino acids, trace elements and more. ClinChek® provides matching quality control materials across the same analyte panels to verify daily method performance and precision.

Methodology and Instrumentation

ClinCal® calibrators are prepared from matrix-matched materials and lyophilized to preserve stability. ClinChek® controls use carefully selected native human matrices, undergo lyophilization and are packaged under an ISO 13485-certified quality system. Typical analytical platforms include:

• HPLC and LC-MS/MS for small molecule quantitation
• Photometric assays for porphyrins, vitamins and enzymatic tests
• Immunoassays for proteins, hemoglobins and transferrins

Main Results and Discussion

The ClinCal® range features single-analyte and multi-analyte calibrator sets available in multiple concentration levels (0–6), enabling accurate method calibration across clinical decision ranges. ClinChek® controls mirror these levels to monitor precision and accuracy daily. Matrix consistency reduces bias from protein binding, ion suppression and preparation variability.

Benefits and Practical Applications

The use of matrix-matched calibrators and controls enhances result accuracy, compensates for extraction inefficiencies, and streamlines method validation. Broad analyte coverage and multiple concentration levels simplify inventory management for clinical chemistry, therapeutic drug monitoring, toxicology, endocrinology and occupational health laboratories.

Future Trends and Opportunities

Emerging trends include integration with laboratory automation and digital QC tracking, cloud-based performance dashboards, and development of calibrators and controls for dried blood spot sampling, multi-omics biomarkers and point-of-care testing. These innovations will support personalized medicine and high-throughput diagnostics.

Conclusion

RECIPE’s ClinCal® and ClinChek® product lines deliver comprehensive, matrix-matched calibrators and controls tailored to a wide range of clinical assays. Their rigorous manufacturing, multi-level formats and broad analyte panels reinforce analytical robustness, traceability and compliance in modern laboratories.

References

No external references were provided.