High Sensitivity Intact Monoclonal Antibody (mAb) HRMS Quantification
Applications | 2018 | WatersInstrumentation
Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordsintact, quantification, mab, hrms, monoclonal, antibody, note, sensitivity, peaks, application, trastuzumab, vion, high, ims, window, qtof, tolerance, uplc, acquity, biotherapeutics, desolvation, ligandbinding, zng, surrogate, peak, class, assays, waters, approach, sensitive, mass, number, based, complimented, highly, method, level, multifaceted, traction, composition, effect, described, results, processing, name, tolerances, emerged, clusters, outcomes, bsa
Similar PDF
Intact Trastuzumab Monoclonal Antibody Quantification Using the Xevo G2-XS QTof High Resolution Mass Spectrometer
2018|Waters|Applications
[ TECHNOLOGY BRIEF ] Intact Trastuzumab Monoclonal Antibody Quantification Using the Xevo G2-XS QTof High Resolution Mass Spectrometer Yun Wang Alelyunas, Henry Shion, Ian Edwards, and Mark Wrona Waters Corporation, Milford, MA, USA In this study, a monoclonal antibody is…
Key words
intact, intactquantification, quantificationhrms, hrmsquantitative, quantitativebrief, briefplatform, platformtrastuzumab, trastuzumabunifi, unifibiotherapuetics, biotherapueticstriplicate, triplicatemonoclonal, monoclonalantibody, antibodydiscovery, discoverymultiple, multiplemolecule
High-Performance Vion IMS QTof for Monoclonal Antibody Intact and Subunit Mass Analysis
2017|Waters|Applications
[ APPLICATION NOTE ] High-Performance Vion IMS QTof for Monoclonal Antibody Intact and Subunit Mass Analysis Henry Shion and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Minimal tuning effort for intact protein Biotherapeutic protein products,…
Key words
intact, intactvion, vionsubunit, subunitims, imsqtof, qtofmab, mabcomposition, compositionmonoclonal, monoclonalantibody, antibodymass, massunifi, unifianalysis, analysisuplc, uplcacquity, acquityglycosylation
Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System
2017|Waters|Applications
[ APPLICATION NOTE ] Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…
Key words
subunit, subunitintact, intactunifi, unifimodification, modificationvion, vionqtof, qtofnist, nistims, imsmass, massmonoclonal, monoclonalantibody, antibodyprotein, proteincharacterization, characterizationmab, mabautomated
PEPTIDE AND PROTEIN BIOANALYSIS
2016|Waters|Guides
[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…
Key words
ionkey, ionkeypeptide, peptideplasma, plasmaquantification, quantificationhuman, humanarea, areaxevo, xevoinsulin, insulinprotein, proteinuplc, uplcpeptides, peptidesmrm, mrmproteinworks, proteinworksantibody, antibodyusing