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Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System

 

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[ APPLICATION NOTE ] High-Performance Vion IMS QTof for Monoclonal Antibody Intact and Subunit Mass Analysis Henry Shion and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Minimal tuning effort for intact protein Biotherapeutic protein products,…
Key words
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[ APPLICATION NOTE ] An Integrated LC-MS Platform for Multi-Attribute Monitoring of CQA’s of mAbs at the Subunit Level Nilini Ranbaduge, Henry Shion, Ying Qing Yu, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Streamlined workflows…
Key words
subunit, subunitcqa, cqascfc, scfcplatform, platformattribute, attributecqas, cqasmonitoring, monitoringmabs, mabsfucosylation, fucosylationintegrated, integratedmodifications, modificationsunifi, unifivion, vionlevel, levelglcnacs
Application Note Establishment of a Robust mAb Subunit Product Quality Attribute Monitoring Method Suitable for Development, Process Monitoring, and QC Release Samantha Ippoliti, Ying Qing Yu, Nilini Ranbaduge, Weibin Chen Waters Corporation Abstract This application note presents a subunit MAM…
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BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…
Key words
unifi, unifibiopharmaceutical, biopharmaceuticaluplc, uplcglycan, glycanacquity, acquityglycoworks, glycoworksplatform, platformglycans, glycanspeptide, peptidebiosimilar, biosimilaranalysis, analysissolution, solutionintact, intactwaters, watersinnovator
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