Quick screening of intact antibody and antibody-drug conjugates with integrated microfluidic capillary electrophoresis and mass spectrometry
Applications | 2017 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Capillary electrophoresis
IndustriesClinical Research
ManufacturerThermo Fisher Scientific
Key wordsmab, nist, adc, mass, relative, zipchip, variants, exactive, biopharma, abundance, lysine, modification, conjugates, drug, sliding, electrophoresis, intact, biotin, dibo, pyroglutamination, antibodies, heterogeneous, antibodydrug, antibody, orbitrap, hmr, adducts, site, terminal, glycosylation, eof, payload, quick, intensity, modifications, conjugation, moiety, screening, through, microfluidic, capillary, glycoforms, option, distribution, charge, heterogeneity, recombinant, characterization, orders, homogenuous
Similar PDF
Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system
2017|Thermo Fisher Scientific|Brochures and specifications
A comprehensive CE/ESI-MS solution for BioPharma applications Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system Fast CE Separation Nanospray Sensitivity HRAM Spectrometry A unique and powerful combination of CE/ESI and MS technology designed for BioPharmaceutical applications Thermo…
Key words
zipchip, zipchipbiopharma, biopharmaexactive, exactiverelative, relativeabundance, abundancefinder, findermass, massmab, mabemtasine, emtasineoption, optionlysine, lysinecarbohydrates, carbohydratesides, idestrastuzumab, trastuzumabinfliximab
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers - for CE/ESI-MS Analyses
|Thermo Fisher Scientific|Presentations
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers -- for CE/ESI-MS Analyses The world leader in serving science Content ZipChip System Introduction ZipChip Separation Mechanism Biopharmaceutical Application Examples Metabolomics Application and System Test Resources and Ordering Information 2 What is…
Key words
zipchip, zipchipexactive, exactivebiopharma, biopharmaabundance, abundancerelative, relativeseparation, separationassay, assaymab, mabachieved, achievedbge, bgekit, kitchip, chipsystem, systemintact, intactnist
Characterization of intact monoclonal antibody with microfluidic chip electrophoresis mass spectrometry
2017|Thermo Fisher Scientific|Posters
POSTER NOTE 65000 Characterization of In Characterization of Chien-Hsun intact monoclonal antibody Chen1, Andreas Krupke2,with Stephane H 1Thermo Fisher Scientific, Chromatography and microfluidic chip electrophoresis mass spectrometry Authors Chien-Hsun Chen,1 Andreas Krupke,2 Stephane Houel,1 Aaron Bailey,1 Aran Paulus,1 Daniel Lopez-Ferrer,1…
Key words
relative, relativebiopharma, biopharmaintensity, intensitymab, mababundance, abundancemass, masschip, chipexactive, exactivefinder, findermicrofluidic, microfluidicglycosylated, glycosylatedantibody, antibodyprotein, proteinterminal, terminalprimed
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutic proteins
2017|Thermo Fisher Scientific|Posters
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutic proteins. Stephane Houel1, Terry Zhang1, Erin Redman2, Scott Mellors2, Aaron Bailey1, Chris Petty2, Aran Paulus1, Kai Zhou1, Jonathan Josephs1., 1Thermo Fisher Scientific, San…
Key words
zipchip, zipchipelectrophoresis, electrophoresisnist, nistmab, mabintact, intactmicrofluidic, microfluidicmass, masslysine, lysineorbitrap, orbitraptrastuzumab, trastuzumabdevice, devicepeptide, peptideemtansine, emtansineexactive, exactivesub