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Enhanced Specificity Provides Increased Quantitative Accuracy When Using SONAR for the Analysis of Low Level Lipids in Plasma-Based Extracts

 

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[ TECHNOLOGY BRIEF ] Analysis of Plasma Proteome for a Respiratory Disease Cohort Using SONAR on a SYNAPT XS Mass Spectrometer Christopher Hughes, 1 Lee Gethings,1 Joanne Ballantyne,1 and Robert Plumb 2 1 Micromass UK Limited, Wilmslow, Cheshire, UK; 2…
Key words
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[ TECHNOLOGY BRIEF ] Increased Specificity, Improved Lipidomic Clarity, and Identification Confidence with SONAR Adam King,¹ Lee A. Gethings,¹ Robert S. Plumb,¹ and Ian D. Wilson² ¹Waters Corporation; ²Imperial College London Implementing SONAR improves spectral clarity and thereby increases certainty…
Key words
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[ APPLICATION NOTE ] Rapid Qualitative Analysis and Absolute Quantification of Plasma Proteins Using SONAR with Biognosys PQ500 for Proteomic Clinical Research Studies Christopher J. Hughes, 1 Sarah Lennon,1 Lee A. Gethings,1 Florian Marty, 2 Sebastian Müller, 2 Lukas Reiter,…
Key words
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[ TECHNOLOGY BRIEF ] Effect of SONAR Quadrupole Window Size on LC-MS Sensitivity and Selectivity Robert S. Plumb, 2 Adam King,1 Lee A. Gethings,1 and Giorgis Isaac2 Waters Corporation, Wilmslow, UK; 2Waters Corporation, Milford, MA, USA 1 SONAR DIA is…
Key words
sonar, sonardia, diawindow, windowquadrupole, quadrupolepeak, peaksensitivity, sensitivitynoise, noisescanning, scanningbrief, briefacquisition, acquisitionsignal, signalmse, mseintensity, intensitycount, countmode
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