An Efficient UV-Based Method for the Assessment of Oleic Acid Content in Biotherapeutic Drug Products Containing Polysorbate-80

 

Similar PDF

Toggle
AN EFFICIENT METHOD FOR THE DETERMINATION OF TRACE EXCIPIENT IMPURITIES IN BIOTHERAPEUTIC DRUG PRODUCTS CONTAINING POLYSORBATE Robert Birdsall, Brooke Koshel, Ximo Zhang, Scott Berger, Ying Qing Yu Waters Corporation, Milford, MA RESULTS INTRODUCTION Figure 2. Dynamic range and internal standard…
Key words
oleic, oleicneat, neatmecn, mecnsir, sirretention, retentionacid, acidtuv, tuvarea, areamin, minpolysorbate, polysorbatetime, timeppm, ppmvolume, volumeexperimental, experimentalyes
AN EFFICIENT METHOD FOR THE DETERMINATION OF TRACE EXCIPIENT IMPURITIES IN BIOTHERAPEUTIC DRUG PRODUCTS CONTAINING POLYSORBATE Robert Birdsall, Brooke Koshel, Scott Berger, Ying Qing Yu, and Weibin Chen Waters Corporation Milford, MA INTRODUCTION RESULTS AND DISCUSSION Polyoxyethylene sorbitan-based nonionic surfactants…
Key words
oleic, oleicmecn, mecnneat, neatretention, retentiontuv, tuvmin, minsir, sirformulated, formulatedpolysorbate, polysorbateacid, acidtime, timearea, areavolume, volumeyes, yessurfactants
[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…
Key words
acquity, acquityqda, qdauplc, uplcdetector, detectormass, massarc, arcdetection, detectionbound, boundcetrimonium, cetrimoniumusing, usingminutes, minuteswaters, watersintensity, intensityclass, classanalysis
Application Note Quantitative Analysis of Polysorbate 20/80 in Protein-Based Biopharmaceuticals Using A One-Pot RPLC-MS Based Platform Method Robert E. Birdsall, David Dao, Brooke M. Koshel, Ying Qing Yu, Aude Smeets, Michel Gerodez, Xavier Taillieu Waters Corporation, GlaxoSmithKline Abstract A high…
Key words
polysorbate, polysorbatemethyl, methylhydrolysis, hydrolysisqda, qdaacquity, acquitylaurate, lauratebased, basedfatty, fattyoleate, oleatesir, sirdetection, detectionneighboring, neighboringmyristate, myristatemethod, methodmethylation
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o., all rights reserved.