Quantitative Analysis of Polysorbate 20/80 in Protein-Based Biopharmaceuticals Using A One-Pot RPLC-MS Based Platform Method
Applications | 2021 | WatersInstrumentation
LC/MS, LC/SQ
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordspolysorbate, methyl, hydrolysis, qda, acquity, laurate, based, oleate, fatty, sir, detection, neighboring, myristate, method, stearate, palmitate, methylation, minimal, raw, elsd, platform, profile, peaks, like, preparation, products, constituents, illustrates, sensitivity, can, sample, efficiency, conditions, could, methanolysis, detector, material, developing, specificity, methylate, gradient, esterase, sans, target, lipase, efficacious, eicosenoate, resolved, amenability, sufficient
Similar PDF
An Efficient UV-Based Method for the Assessment of Oleic Acid Content in Biotherapeutic Drug Products Containing Polysorbate-80 
2018|Waters|Applications
[ APPLICATION NOTE ] An Efficient UV-Based Method for the Assessment of Oleic Acid Content in Biotherapeutic Drug Products Containing Polysorbate-80 Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ A robust and…
Key words
oleic, oleicacid, acidbiotherapeutic, biotherapeuticassessment, assessmenttuv, tuvinfliximab, infliximabefficient, efficientneat, neatdrug, drugacquity, acquitycontent, contentmecn, mecnsir, sirbased, basedtrastuzumab
Excipients: QUALITY ASSESSMENT OF POLYSORBATES 80 AND 20 PHARMACEUTICAL RAW MATERIALS BY MEASURING FATTY ACIDS COMPOSITION USING HPLC WITH MASS DETECTION
2022|Waters|Posters
QUALITY ASSESSMENT OF POLYSORBATES 80 AND 20 PHARMACEUTICAL RAW MATERIALS BY MEASURING FATTY ACIDS COMPOSITION USING HPLC WITH MASS DETECTION Authors: Margaret Maziarz, Paul Rainville, Isabelle VuTrieu, Andrew Leightner Affiliations: Waters Corporation, Milford, MA The U.S. Pharmacopoeia specifies a gas…
Key words
apex, apexoleic, oleicpalmitic, palmiticfatty, fattystearic, steariclinoleic, linoleicacid, acidmyristic, myristicpalmitoleic, palmitoleicminutes, minutesintensity, intensityvaccenic, vaccenicpolysorbates, polysorbatesacids, acidselaidic
Comparing ELSD and CAD Performance on Polysorbate Quantification in Infliximab Drug Products
2022|Waters|Applications
Application Note Comparing ELSD and CAD Performance on Polysorbate Quantification in Infliximab Drug Products Duanduan Han, Robert E. Birdsall, Jennifer Simeone, Michael Fogwill, Ying Qing Yu Waters Corporation Abstract This application note reports a baseline subtraction processing method in Empower…
Key words
polysorbate, polysorbateelsd, elsdcad, cadinfliximab, infliximabcomparing, comparingdrug, drugquantification, quantificationproducts, productsperformance, performanceintact, intactsubtraction, subtractionaerosolized, aerosolizedprocessing, processingconcentration, concentrationmanufacturing
Quality assessment of Polysorbates 80 and 20 Pharmaceutical Raw Materials by Measuring Fatty Acids Composition using HPLC with Mass Detection
2023|Waters|Posters
Quality assessment of Polysorbates 80 and 20 Pharmaceutical Raw Materials by Measuring Fatty Acids Composition using HPLC with Mass Detection M123008-52 Margaret Maziarz, Paul Rainville Waters Corporation, 34 Maple Street, Milford MA CONTACT INFORMATION: [email protected], [email protected] PURPOSE Polysorbates are non-ionic…
Key words
fatty, fattyoleic, oleicpalmitic, palmiticpolysorbates, polysorbatesacids, acidsstearic, stearicpalmitoleic, palmitoleicpolysorbate, polysorbatecomposition, compositionmyristic, myristicminutes, minuteslinoleic, linoleicexcipients, excipientshydrolyzed, hydrolyzedhplc