Identification of novel pyrimidine ring cleavage metabolites of Buspirone via Spectral Similarity correlation score
Posters | | ShimadzuInstrumentation
LC/TOF, LC/MS, LC/MS/MS, LC/IT
IndustriesPharma & Biopharma, Metabolomics
ManufacturerShimadzu
Key wordsloses, pyrimidine, metabolites, neutral, msn, cleavage, formula, parent, predicted, ring, fragments, unknown, unexpected, identify, spectral, drug, metabolic, similarity, identifying, dealkylation, explicit, metid, fragment, novel, therefore, search, scrutiny, buspirone, cleavages, looks, common, unlikely, empirical, similarities, scoring, oxidative, scientist, data, scores, process, peaks, solutions, attributed, combinations, simplicity, metabolism, score, reactions, literature, knowledge
Similar PDF
Isotope modeling routines applied to empirical formula prediction
|Shimadzu|Posters
C146-E090 Isotope modeling routines applied to empirical formula prediction Simon Ashton1 ; Richard Gallagher2 ; Neil Loftus1 ; John Warrander1 ; Ichiro Hirano3 ; Shinichi Yamaguchi3 ; Norio Mukai3 1 Shimadzu ISS, Manchester, UK ; 2AstraZeneca, Alderley Park, Macclesfield, UK…
Key words
msn, msnmass, masscandidate, candidateempirical, empiricaldata, datacomplement, complemention, ionaccuracy, accuracylikelihood, likelihoodfragment, fragmentprediction, predictionformulae, formulaeexperimentally, experimentallyisotope, isotopecandidates
Assessing metabolic profiles in chimeric PXB mouse with humanized livers following oral dosing of troglitazone
|Shimadzu|Posters
Assessing metabolic profiles in chimeric PXB mouse with humanized livers following oral dosing of troglitazone. Alan Barnes1; Neil J Loftus1; Kirsten Hobby1; Ian Wilson2; Yoshio Morikawa3 1Shimadzu MS/BU, Manchester, UK; 2Astra Zeneca, Alderley Park, Cheshire, UK; 3PhoenixBio Co. Ltd, Higashi-Hiroshima,…
Key words
pxb, pxbscid, scidhydroxy, hydroxytgz, tgzglucuronide, glucuronidediacylglycerophosphocholine, diacylglycerophosphocholinesulfate, sulfatetroglitazone, troglitazonemetid, metidhydrated, hydratedmice, miceglycerophosphocholine, glycerophosphocholinemsn, msnenabled, enabledliver
High Resolution Designer Drug Screening using a High-Sensitivity Q-TOF Mass Spectrometer and an Extended Tandem Mass Spectrum Library
2019|Shimadzu|Posters
PO-CON1880E High Resolution Designer Drug Screening using a High-Sensitivity Q-TOF Mass Spectrometer and an Extended Tandem Mass Spectrum Library ASMS 2019 Jeff Dahl1, Rachel Lieberman1, Yuka Fujito1, Joseph Kahl2 and Alex Giachetti2 1 Shimadzu Scientific Instruments, Columbia Maryland, 2 Miami-Dade…
Key words
designer, designerlibrary, libraryspectrum, spectrumtof, tofmass, masshigh, highauthentic, authenticextended, extendedtandem, tandemchminaca, chminacaspectrometer, spectrometerdrug, drugscreening, screeningsensitivity, sensitivityresolution
LCMS-IT-TOF Analysis of Amoxicillin
|Shimadzu|Applications
Liquid Chromatography Mass Spectrometry LCMS-IT-TOF Analysis of Amoxicillin The Shimadzu LCMS-IT-TOF incorporates the higher MS stages available with an ion trap and the high resolution and mass accuracy of a time-of-flight (TOF) mass spectrometer, leading to the only mass spectrometer…
Key words
tof, toflcms, lcmsmass, massamoxicillin, amoxicillintrap, trapaccuracy, accuracyion, ionions, ionstissues, tissuesconfirming, confirmingshimadzu, shimadzuanimal, animalfocused, focusedshimpack, shimpacklcmssolution