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Assessing metabolic profiles in chimeric PXB mouse with humanized livers following oral dosing of troglitazone

 

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PO-CON1252E Mass spectrometry based assessment chimeric mouse liver metabolite profiles following oral dosing of troglitazone IMSC 2012 PWe-093 Alan Barnes1; Neil J Loftus1; Kirsten Hobby1; Ian Wilson2; Yoshio Morikawa3 1 Shimadzu MS/BU, Manchester, UK; 2 Astra Zeneca, Alderley Park, Cheshire,…
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[ APPLICATION NOTEBOOK ] UNTARGETED METABOLOMICS AND LIPIDOMICS 1 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Development of a Metabolomic Assay for the Analysis…
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A strategy using isotopic fine structure to reveal potential biomarkers showing the effects of traditional Chinese medicines on Alzheimer disease in rats Alzheimer disease (AD) is a progressive, unremitting, neurodegenerative disease characterized by progressive memory decline and subsequent loss of…
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ASMS 2019 ThP-400 Oxygen Attachment Dissociation MS/MS for Differentiation between Cis and Trans Fatty Acids Hidenori Takahashi1; Yuji Shimabukuro2; Daiki Asakawa3; Shosei Yamauchi1; Shinichi Iwamoto1; Motoi Wada2; Koichi Tanaka1 [1] Shimadzu corp., Kyoto, Japan; [2] Doshisha University, Kyoto, Japan; [3]…
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