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Lipid Visualization and Identification Through Collisional Cross Section Aided Correlation of MS Imaging and Ex Situ MS Data for MS-MS Identification

Technical notes | 2015 | WatersInstrumentation
Ion Mobility, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Lipidomics
Manufacturer
Waters
Key words
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[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…
Key words
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectionmobility, mobilitydefinition, definitionion, ionhdms, hdmsbiomarker, biomarkerimage, imagexenograph, xenographdesorption, desorptionionization
Intensity (arb. unit) 132% 0% 100% PS 38:1 m/z 816.5747 ± 0.0122 1/K0 1.433 ± 0.01 Intensity (arb. unit) Mobility [1/K0] 136% 0% 100% PE 20:1_22:6 m/z 816.5517 ± 0.0122 1/K0 1.404 ± 0.01 m/z 1 mm CCS-aware SpatialOMx® enables…
Key words
ccs, ccsmaldi, maldispatialomx, spatialomximaging, imagingaware, awareannotation, annotationmobility, mobilitytims, timsannotated, annotatedannotations, annotationsbucket, bucketpasef, paseflipid, lipidsegmentation, segmentationlipids
MALDI Mass Spectrometry Imaging Reveals Distinct Spatio-Molecular Phospholipid Distributions in Mouse Lungs While phospholipids play key roles in lung physiology and pathology, the complex composition and function of the lipidome in the lungs is poorly understood. We applied MALDI mass…
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imaging, imagingtissue, tissuelungs, lungsimages, imagesmaldi, maldiphospholipids, phospholipidsdistributions, distributionslung, lungwere, werenegative, negativeion, ionpositive, positivescils, scilsspatial, spatialbruker
[ APPLICATION NOTE ] DESI MS Imaging Using SONAR™: A Novel Method to Image Precursor Ions and Fragment Ions for Molecular Identification in a Single Experiment Emmanuelle Claude Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION DESI MS…
Key words
imaging, imagingsonar, sonardesi, desiquad, quadscanning, scanningwindow, windowscan, scantissue, tissueprecursor, precursormsi, msinote, noteapplication, applicationcorrelation, correlationbrain, brainspatial
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